LOCUS       NM_001108590            2568 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus erythrocyte membrane protein band 4.2 (Epb42),
            mRNA.
ACCESSION   NM_001108590 XM_001076442 XM_342503
VERSION     NM_001108590.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Robledo RF, Ciciotte SL, Gwynn B, Sahr KE, Gilligan DM, Mohandas N
            and Peters LL.
  TITLE     Targeted deletion of alpha-adducin results in absent beta- and
            gamma-adducin, compensated hemolytic anemia, and lethal
            hydrocephalus in mice
  JOURNAL   Blood 112 (10), 4298-4307 (2008)
   PUBMED   18723693
REFERENCE   2  (bases 1 to 2568)
  AUTHORS   Peters LL, Jindel HK, Gwynn B, Korsgren C, John KM, Lux SE,
            Mohandas N, Cohen CM, Cho MR, Golan DE and Brugnara C.
  TITLE     Mild spherocytosis and altered red cell ion transport in protein 4.
            2-null mice
  JOURNAL   J Clin Invest 103 (11), 1527-1537 (1999)
   PUBMED   10359562
REFERENCE   3  (bases 1 to 2568)
  AUTHORS   Bouhassira EE, Schwartz RS, Yawata Y, Ata K, Kanzaki A, Qiu JJ,
            Nagel RL and Rybicki AC.
  TITLE     An alanine-to-threonine substitution in protein 4.2 cDNA is
            associated with a Japanese form of hereditary hemolytic anemia
            (protein 4.2NIPPON)
  JOURNAL   Blood 79 (7), 1846-1854 (1992)
   PUBMED   1558976
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168935.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001108590.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168935.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..2568
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /note="erythrocyte membrane protein band 4.2"
                     /db_xref="GeneID:362202"
                     /db_xref="RGD:1305306"
     exon            1..131
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..2191
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /note="erythrocyte protein band 4.2"
                     /codon_start=1
                     /product="protein 4.2"
                     /protein_id="NP_001102060.1"
                     /db_xref="GeneID:362202"
                     /db_xref="RGD:1305306"
                     /translation="MGQALSIKSCDFHAAENNKEHHTDAISSQHLILRRGQSFTITLN
                     FRAPAHIFLSALKKVALIAQTGEQPSKTSKTQAIFPISSLGDKKGWSAAVVERDAQHW
                     TISVTTPVDAVIGHYSLLLQVSGKKQYPLGQFTLLFNPWNRDDAVFLQNEVQRTEYVL
                     NQDGFIYLGTADCIQEEPWDFGQFERDVMDLSLNLLSVDKQVKDWSQPAHVACIVGAL
                     LHALKKKSVLPISQTQAAQQGALLYKRRGSVPILRQWLTGRGRPVYESQAWVFAAVAC
                     TVLRCLGIPARVVTTFDSAQGTNGSLLVDEYYNEEGLQNGEGQRGHIWVFQTSVECWM
                     NRPDLSPGYDGWQILHPRAPNGVGVLGSCNLVPVKAVKEGDLQLDPAVPELFAAVNAS
                     CVVWKCCEDGKLELTNSNRKNVGNSISTKVVGSDRCEDITQNYKYPEGSLQEKEVLER
                     VQKERMKLGEDTCPPSCEPGDPLHLFLEVPSSQPLRGNGRLSVALINPTDKEKEVELV
                     IAAQALYYNGVLATGLWRQKQFLMLGPNQVLRLSTSLSFSCFEQNPPENTFLRVTAMA
                     RHSHAGFSCFAQEDVVISRPNLVIEMPKRATQYQPLTASVRMHNSLDAPMQNCIISIF
                     GRGLIHREKRYGLGSVWPGSSLHTQFQFTPTHLGLQRLTVEVDCDMFQNLTGHRSVLV
                     VAPEVSV"
     exon            132..317
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            318..551
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            552..670
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            671..775
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            776..953
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1092
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1196
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1439
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1733
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1734..1894
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..2028
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2548
                     /gene="Epb42"
                     /gene_synonym="Epb4.2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctttaaacca gaagtccacc atcttcgccg gtgtggaggt agatttggag agagaatcca
       61 gagagaagca acagagggag gtcagcgtct cctgagctgt ggactcaagt agcctgcagc
      121 catgggacaa gctctgagta tcaagagctg cgacttccac gcagcagaaa acaacaagga
      181 gcaccacacc gacgccatca gctcccagca ccttattttg aggaggggac agtccttcac
      241 catcaccctg aacttccgtg ccccggccca catatttctg tctgccctga agaaagtggc
      301 tctcattgca caaactggag agcaaccttc caagaccagt aagacccaag ccatattccc
      361 tatttcctcc ctgggggaca aaaaagggtg gagtgcagca gtggtggaaa gagatgccca
      421 acattggacc atctctgtga ccacgcccgt ggatgctgtc attggccact actcactcct
      481 gcttcaggtt tccggcaaga aacaataccc cttgggccaa ttcacactgc tctttaatcc
      541 atggaataga gatgatgctg tatttctgca gaacgaggtt caacgcactg aatatgtact
      601 gaatcaggat ggctttatct acctgggcac agctgactgc attcaagaag agccctggga
      661 cttcggtcag tttgagagag acgtcatgga cctcagcctg aacttactga gtgtggacaa
      721 gcaagtgaaa gactggagcc agcctgcaca cgtggcctgc atagtgggcg ccttgttgca
      781 tgccctcaag aagaagagtg tcctgcctat ttcacagacc caggctgccc agcaaggtgc
      841 cttgttgtac aaacgacgag gcagtgtgcc catcctgagg cagtggctca ctggccgagg
      901 acgacctgtg tatgagagcc aggcgtgggt gtttgctgct gttgcttgca cagtgctacg
      961 atgcctgggc atcccagctc gagttgttac cacatttgac tcagcccaag gtaccaatgg
     1021 gagcctgctg gtggatgagt actacaatga ggaggggctc cagaatggag aaggacagag
     1081 gggccatatc tgggtcttcc aaacttctgt agaatgctgg atgaacagac ctgatttgtc
     1141 cccgggttat gatggatggc agattctgca cccaagagct cctaatggag ttggagtcct
     1201 gggatcctgc aatctggtcc cagtcaaagc agtcaaagag ggggacctgc agctggaccc
     1261 ggcagtacca gagctctttg ccgcagtgaa tgcctcgtgc gtggtctgga agtgctgtga
     1321 ggatgggaag ttggagttga ccaactccaa cagaaagaat gttggcaaca gcatcagcac
     1381 caaggtcgtg ggcagtgacc gctgcgaaga catcacccag aactacaaat atcctgaagg
     1441 atctcttcaa gaaaaggagg tactggagag agtccaaaaa gaaagaatga aacttgggga
     1501 agacacgtgt cctcctagtt gtgagcctgg ggatcctctg cacctgttct tggaagtacc
     1561 tagctcccag cctctgagag gaaatggtcg gctctcagtg gccttgatta accccacaga
     1621 caaggagaag gaggtagaac tggtgattgc ggcccaggct ttgtactaca atggagtcct
     1681 tgctactggg ctctggaggc agaagcagtt cctcatgctc ggacccaacc aggttctgag
     1741 actctccacc agcctgtcct tctcctgttt cgaacaaaac ccacctgaga acacctttct
     1801 cagagtcaca gcaatggcaa ggcactccca cgctggcttc agctgctttg ctcaggaaga
     1861 tgtggtcatc agtagaccga atcttgtcat tgagatgcca aagagagcaa cacagtatca
     1921 gccccttact gcctcagtta gaatgcacaa ctccttagac gcccccatgc agaactgcat
     1981 catctccatc tttggaaggg gactcattca cagagaaaag agatacggat tgggttctgt
     2041 gtggccagga agcagcctgc atactcagtt ccagttcacc ccaacacatc tggggctcca
     2101 aaggctcact gtggaagtag attgtgacat gttccagaac ctgaccggcc acagaagtgt
     2161 ccttgtggtg gcccctgaag tttctgttta aactccaaac aaccttcaga cttctaaagc
     2221 tagacatgct ccagagggaa actctaccta tcagacaaat gagtctatac taaagttgaa
     2281 cagaccggtg accaaaaacc aaaattcatt tttttcttgt ttttttttgg gggggtggtt
     2341 tgtttttgtt tgtttgtttg tttgtttttg ttgttgttgt tttttggtta tttggtgggt
     2401 attttcgaaa cagagtttct ctatgtagtc ctggtggtcc tggaactcac gctgtagatc
     2461 aggctggcct tgaactcaga gatccacctg cctctccctc ccgagtgctt ccattaaagg
     2521 catgtgccac cattgtctgg ctccaaaaaa aaaaaaaaaa aaaaaaaa
//
