LOCUS       XM_006227692            3978 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus ectonucleotide
            pyrophosphatase/phosphodiesterase 1 (Enpp1), transcript variant X1,
            mRNA.
ACCESSION   XM_006227692
VERSION     XM_006227692.4
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086019) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_006227692.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3978
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..3978
                     /gene="Enpp1"
                     /gene_synonym="Npps; Pc1"
                     /note="ectonucleotide pyrophosphatase/phosphodiesterase 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 16 ESTs, 69 long SRA reads, 14
                     Proteins"
                     /db_xref="GeneID:85496"
                     /db_xref="RGD:628825"
     CDS             25..2742
                     /gene="Enpp1"
                     /gene_synonym="Npps; Pc1"
                     /codon_start=1
                     /product="ectonucleotide pyrophosphatase/phosphodiesterase
                     family member 1 isoform X1"
                     /protein_id="XP_006227754.1"
                     /db_xref="GeneID:85496"
                     /db_xref="RGD:628825"
                     /translation="MERDGEQAGQGPRHGPAGNGRELESPAAASLLAPMDLGEEPLEK
                     AERARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFSNC
                     RCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVCSCADDCKAHNDCCI
                     NYSSVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVIS
                     KLKNCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKE
                     KFNPLWYKGQPIWVTANHQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILA
                     VLEWLQLPSYERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDL
                     GLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYS
                     FNYEALAKNLSCRETNQHFRPYLKHFLPKRLHFAKNDRIEPLTFYLDPQWQLALNPSE
                     RKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPN
                     NGSHGSLNHLLKKPIYTPSHPKEESFLSQCPIKSVSSDLGCTCDPSIVPIMDFEKQFN
                     LTTDAEDVYSMTVPNGRPRNLQKQHRVCLLHQQQFLTGYSLDLLMPLWTSYTFLSNDQ
                     FSTDDFSNCLYQDLRIPLSPMHKCSYYKSTSKLSYGFLTPPRLNRVSRQIYSEALLTS
                     NIVPMYQSFQVIWQYLHDTVLRRYAQERNGVNVVSGPVFDFDYDGRYDSSEILKQNTR
                     VIRSQENLIPTHFFIVLTSCKQLSESPLKCTALESSAFLLPHRPDNIESCTHGKQESA
                     WVEELLALHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED"
     polyA_site      3978
                     /gene="Enpp1"
                     /gene_synonym="Npps; Pc1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 ggccggcggg ggcagagcgg ggcgatggag cgcgacggcg aacaggcagg gcaagggccc
       61 cggcatgggc cagcgggaaa cggccgcgag ctggagtctc cagccgccgc ttcgctgctg
      121 gcgcccatgg acctagggga ggagccgctg gagaaggcgg agcgtgcgcg caccgccaaa
      181 gaccccaaca cctacaaagt gctgtcgctg gttttgtcag tatgcgtgct aacaactatt
      241 cttggttgta tctttgggtt gaaaccaagc tgtgccaaag aagtgaaaag ttgcaaaggc
      301 cgctgctttg aaaggacgtt cagcaattgt cgctgcgatg ctgcctgtgt cagccttggg
      361 aactgctgtc tggatttcca agagacctgt gtggaaccaa cacatatatg gacttgcaac
      421 aagttcaggt gcggcgagaa gaggctgtcc agatttgtgt gctcctgtgc ggacgactgc
      481 aaagcccaca atgactgttg catcaactac agttcagtgt gccaagaaaa gaagagttgg
      541 gtagaagaag cctgcgaaac catcgatgca ccacagtgtc cagcagagtt tgaatcaccc
      601 cctactctct tgttttcttt ggatggattc agagctgaat atttgcacac ttggggtgga
      661 cttcttcctg tcattagcaa gctgaaaaac tgtggaacgt acactaaaaa catgaggcct
      721 gtgtacccta ccaagacgtt tcccaatcat tacagcatcg tcacaggact ttatccagaa
      781 tcacatggca taattgacaa caagatgtat gatcctaaaa tgaacgcttc tttctcactt
      841 aaaagtaaag agaaattcaa ccctctgtgg tacaaaggac agccgatctg ggtgaccgct
      901 aatcatcagg aggtcaggtc tggcacatac ttctggccag gatcagacgt ggaaattgat
      961 gggattctgc cagatatcta caaagtgtat aatgggtcag taccatttga agaaaggatt
     1021 ttagctgttc tcgagtggct acagcttcct agctatgaaa gaccacactt ttacactctg
     1081 tatttagaag aaccagattc ttcagggcat tcacacggac cagtaagcag tgaggtcatc
     1141 aaggccctgc agaaggttga ccacatagtt ggcatgctga tggatggcct gaaggacctg
     1201 ggcttggata aatgcctgaa cctcattctc atttcagatc acggcatgga acaaggcagt
     1261 tgtaagaagt acgtgtacct gaataagtac ctgggggatg tgaacaatgt caaggttgtg
     1321 tatggacctg ctgctcgatt gagacccacc gaggttccgg agacatacta ttcgtttaac
     1381 tatgaagccc ttgcaaaaaa tctttcttgc cgggaaacaa accagcactt ccggccttat
     1441 ctgaaacact tcttacccaa gcgcttacac tttgctaaaa atgacaggat tgagccactg
     1501 accttctatc tggaccctca atggcaactt gccttgaatc cgtcagaaag gaaatattgt
     1561 ggaagtggat ttcatggctc tgacaacctg ttttcaaaca tgcaagctct cttcattggc
     1621 tatggacctg ccttcaagca cggtgctgag gttgactcct ttgaaaatat cgaggtctat
     1681 aacttaatgt gtgatttatt gggtttgatc ccagctccta ataatggaag tcacggcagt
     1741 ctcaaccatc ttctaaagaa acccatttat accccaagtc atcccaaaga agagagcttc
     1801 ctgtcccagt gtccaatcaa atcagtgtcc agtgacctcg gctgcacatg tgacccctcg
     1861 attgtgccga tcatggactt cgagaagcag ttcaatctga ccacggatgc tgaggatgtt
     1921 tactctatga ctgtgcccaa cgggaggccc cggaatctgc agaagcagca ccgcgtctgt
     1981 ctgctccatc agcaacagtt tttgactggg tacagcctgg acctcctcat gcccctgtgg
     2041 acgtcttaca cctttctcag taatgaccag ttctccacag atgacttttc caactgtttg
     2101 taccaggacc ttcggattcc ccttagtccc atgcataaat gttcctatta taaaagcact
     2161 tctaagctca gttatgggtt ccttacaccg ccaagactaa acagagtctc acgtcaaata
     2221 tattctgaag ccttgcttac ttctaacata gtgccaatgt accagagttt tcaagttata
     2281 tggcaatacc ttcatgacac cgtactgcga aggtatgccc aagaaaggaa tggcgtcaat
     2341 gttgtcagcg gccccgtgtt cgactttgat tatgatggac ggtatgattc ctcagagatc
     2401 ctgaaacaaa acaccagagt catccgcagt caagaaaatc tgattcccac tcacttcttc
     2461 attgtgctta ccagctgcaa gcagctgtct gagagcccct taaagtgtac agccttagag
     2521 tcttcagcct tcctcttgcc tcacaggcct gataacatcg agagctgtac acatggaaag
     2581 caggagtctg catgggttga agagttgctg gcattgcaca gagctcgggt cacagacgtt
     2641 gagctcatca cgggtctcag cttctaccag gaccgacagg agtcagtttc agaactgctg
     2701 aggttgaaaa cacacttacc aatcttcagc caagaagact gattgttttt tattaaaaaa
     2761 aaaaaaacaa aacaccatag atctttttga aagagtctta tattttatac agtcctctac
     2821 acttttgcaa tgtttggaag ctgtaaagtg gagttaaaac tgggagtccc atgtggtgct
     2881 ggtgtctcca ggctgtgcga caaccccaca cgtctgtaga gtgttcctgt cctgtgccgt
     2941 gcagatttcc tgtctaagaa ttagatgtgt tcctaatgcg ctaggagtaa agacacttca
     3001 cctcacaccc agaagtgctc ttgggtctcc cttatgggac aaggggcagt gaacatggtc
     3061 tggggacctg atgttggaat cgtgctattg ttaataaaac taggtaaagg actggggtag
     3121 ctcatgaccc attaagaaaa agggaaaact gtcttggatt aatttttatc tagagactga
     3181 gttttaattc agtgaggtcc tatttctatc ttttctttct cctccgccaa taaccaaata
     3241 gttggccttg tgcttttaaa acaaattgtg atcggatctc ttcaggtgta gtgactttca
     3301 aaaattggac tttgatggaa aatttgtgag ttgagtgtat ctagctttta taaaaaatca
     3361 gactctacat ttgtatacac ctgaacaagt gcacatgtac atgctcttgc acatgcacac
     3421 acacacacac acacacacac tcacactcac acacgtgtac atgtgcacgc tctcccaata
     3481 cgcgtcccag ttctcttcac tagaaataaa tgaagaccaa aaaagagccc tgagcatggc
     3541 tttctcaggc cattaaaatt aggcttcgtt tgggtgaaac cccagagaac tattggcatt
     3601 tacaaagtga cattttttca tcgagaagag tgtttcctcg cacaagagac cggccagtgg
     3661 aagaaggact ttacctggcc tagctcttca atttgaagct gtgtcgataa gaagagaatg
     3721 tgtcacccct cacttaacat cttcactatg cacacaacga atgacacgct gatgtaattt
     3781 cccctctgca ttgattctgc ccttgttcca accggtgatc ctccagaggc tgtgttacat
     3841 tttaggtttc ctgggtccat tttgatataa tattacccta ccaaagattt tcatatgtcc
     3901 ttcctaggat aatcattcct tttgtcatct gtaaagatgt ttaggtaata aaacttgcaa
     3961 tcaacattgc catgataa
//
