LOCUS       XM_017602395            9500 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ecto-NOX disulfide-thiol exchanger 2
            (Enox2), transcript variant X1, mRNA.
ACCESSION   XM_017602395
VERSION     XM_017602395.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017602395.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017602395.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9500
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..9500
                     /gene="Enox2"
                     /note="ecto-NOX disulfide-thiol exchanger 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 7 ESTs, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 6 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:302817"
                     /db_xref="RGD:1563643"
     CDS             6568..8520
                     /gene="Enox2"
                     /codon_start=1
                     /product="ecto-NOX disulfide-thiol exchanger 2 isoform X1"
                     /protein_id="XP_017457884.1"
                     /db_xref="GeneID:302817"
                     /db_xref="RGD:1563643"
                     /translation="MFLVQYTGLNQLPFDPANNNEPLQFGSASGPLVPEGLIENGGES
                     SKKRKRTNAPSADNTRTLNVDSAAMTLPVSDPTAWATAMNNLGMAPLGIAGQPILPEF
                     DPALGMMTGIPPITPMMPGLGIVPPPIPPDMPVVKEIIHCKSCTLFPPNPNLPPPATR
                     ERPPGCKTVFVGGLPENGTEQIIVEVFEQCGEIIAIRKSKKNFCHIRFAEEYMVDKAL
                     YLSGYRIRLGSSTDKKDTGRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERMR
                     PPSPPPVVHYSDHECSIVAEKLKDDSKFSEAVQTLLTWIERGEVNRRSANHFYSMIQS
                     ANSHVRRLVNEKAAHEKEMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTK
                     AQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEETTETKETEESALVSQA
                     EALKEENDSLRWQLDAYRNEVELLKQEQGKAHREDDPNKEQQLKLLQQALQGMQQHLL
                     KVQEEYKKKEAELDRIKDDKLQVEKLLENLHEKQENCTSRLCASSQESDHPLEKAIIG
                     NPVKSEREALLVGIISTFLHVHPFGASIEYICSYLNRLDNKICTSDVESLMSRLQHTF
                     RQEMTGVGASLEKRWKFCGFEGLKLT"
ORIGIN      
        1 gacagacaga cagttagttg gtatgtatgt gtgtatacca tagcatatac atgcaggtta
       61 gaagacaact tgtggatcag actcagttca tgagatttgg tggcaagtgc cttcaccggc
      121 taagccattt tgccagtccc tgtatttctt tttattacct gcattgccac ctattcatcc
      181 tcttatgcct ttcaaactaa gttttaccat aactacaatt tttctaaata cttcagtatt
      241 catatcatta gctgcataaa gaaatgtttt tgtgctctga aatcaatcaa accctccaat
      301 tatacctgca ttcgctatat gctgccaaaa ctctaatctg cttggatgtt gtaggtctgc
      361 ttttcaatgg aacatgtatt tctttgacta attttgaaat gtcctcctgt tttatctagt
      421 gcagtgccag gcacatagtc cataaatacc acttgatgtt gttgaacaga gacagcgtta
      481 ggtcatgggg aagaaatgct aaaagtcaga atacacagag gaagggaggg ggaaaggagt
      541 gtattagaag gtcacagtgg aatgggaggt agtcattcag gacttgaagt attctgggaa
      601 gaaggatgct acagttcact aagtactccc tgcagtacct ctattttctt agctctctct
      661 ttagaagcag tggttctagg aaactagaca aaattgttgc ttggtatagc acatggtaag
      721 tctccttgtt aaataccacc aattaatatt tcgttctcct ttattaacca atgcacctta
      781 attttggaca ccgtggttgg gctatctgtg ctatatcctt tagagcacct gagctctgta
      841 accctggttt ctgttttcct cataacattt cctcttttgc catatcactt aagttacaaa
      901 gagaactcta atctgctttg attgagcagt aattttgtgt caagtattgt gctagctgct
      961 atcacatcag taacacttta caaaaatctg acaacacact tctttctcca ttcgccagac
     1021 accccaaccc ccacaaacaa aacaaaacaa aacacaagtt agaattcatg aagctcaagt
     1081 ctgtccacct agagaaccta acagtctcaa gtattacatt agatcatctg atggcatttt
     1141 aaaacatcaa ttaacaaata accacaacag cacaaccagg gaccagagag gtggcttaat
     1201 gggttaagat actttctgcc agtcctgatg agctgaatta aacccctgga attcacaaag
     1261 tagaatgaga gaaccactcc ctttgatcca cacgtgctgt atgtaatatt tatgtccatg
     1321 tgcaagcaca caagtgcaca tgagcgaaca caaagacaat aaacaaaggt tagaaaagac
     1381 aaatagaaat acaaggaact ctacctttac ttggtggctc agcatgtgat ttattcatta
     1441 agcattttca gttgtatgat tgaattagaa agtatgccct aatcattaag atgttggttt
     1501 agtaaggatt ctggttgctt gagttcaaat ctcaatcttt tcatggtagt tgattgacta
     1561 agttctcatt taacataagg tggccaattt tcttgcttag aaatgtatat aatacctaaa
     1621 caacattgta ttgtgtggac tgattaatgc aactatttga aatactgtgc cgtgtctagt
     1681 atacactaga tgatcaccat attttagatt actcccctcc tttcatattt ttttgggggg
     1741 aatcacactg ttcaactata actttcactt gaaaatgaca aagttgtaaa tgtaactttt
     1801 attgactaaa tgtaattgtc tcagaggctg actgctgaat aagctcaccc tttctagttc
     1861 tttctgaact ctggctggct ggttcaactc aactgttttt gctcaaactt ctctccgtgc
     1921 taactgatac aaactggctt ctcttgcctt ctccctgaat ttctctggtc tcaaagtaat
     1981 tttggcaatt tgttttaatc ttctagctcc ttctgattct ctgactttaa ctgcctctgc
     2041 tgaactgcac tgtacaaact gcacaaactg aactccactg cattgtttga acttaacatc
     2101 actctagcct tccatttcct gacatctctg tcaaatcttt ctctgattcc tcactgtgtc
     2161 tgcccctgtt ggattgatta tatatcattt caaataccgc tgctttcttt cacaaactaa
     2221 ctttaccttc actgtttaag attaaaggtg tggggctggg gatttagctc agtggtagag
     2281 cgcttaccta ggaagcgcaa ggccctgggt tcggtcccca gctccgaaaa aaaaaaagaa
     2341 caaaaaaaaa gattaaaggt gtatactaag ggagtgtttg tattccagca gattatactg
     2401 taatccagaa tgtgactgaa tttctgccag atcacatagg cctagaacat ttttggacct
     2461 gatcccttgc cagagtagct atgttactgg attaaaattc ctctacacaa agtgtcccta
     2521 aaacattttt ttcgagcaaa tatcttttta aaaaaggact gttgaggtgc tttttctttt
     2581 gagtcttaac aagacaagct accaactctt atgtaaaacc tatttcaaaa taagctatgt
     2641 aaaataggag gtatcaattc acaagacagc tagttgtggt aaggataggc actgagggag
     2701 tattgacaag ttgtatagct tggtgttctt atgcgactcc caacaggatg agtcttttac
     2761 ctgactcttt tgcctgctct tgggaccctt ttttcctgct gggttgcctc ctccaacttt
     2821 gttatgaggg tttgtgccta gtcttatcaa aagttgatat gccatgtttg gttgatatcc
     2881 ctgggcagct ggctcttttc tgaagggaaa ctggaggagg agtggctaga ggagagatga
     2941 gtggggactg gaaggagagt agacagggga aacttcagtt gggatgtaat gtataagaga
     3001 cgaatgagag caagagagac ttgtgatgag tatctgtgct tcttagctct cggggccaag
     3061 ttgcgatgtc atttaatttt ttcactacac tagatattga caatactagc acaggccgtt
     3121 tcaaagccag caagacaagg ctaagagaat ggaagtgact tgaacaaggt caaactgcta
     3181 aaaaaataaa aatgaataaa acagaagagt ctgttctcct gattcttttc ccctttgaga
     3241 gcttttaagc ttttaagtct gcttacagta tgccctttac agaaacttga actgtatgtt
     3301 ctatgagggt ttgtcaaatg tgatggattc caaaaacctg aaggttagtc atggttcaaa
     3361 ttagttcatt atttcttact ttactgtatt cttaaatttt cattttaagg tttagcaaat
     3421 taatgttgtt cctttctgtt gaagtttatg gcttggttca aattcttgat tcagttacat
     3481 cttccattgg gacttttgtt tttgacaaat acacctggaa tcccagatgg ttaatgacct
     3541 aatttatgtg accagtgact tgcgatatgg agtgactgct gaggggaagc tcaaggatct
     3601 cattcatgct tgggttttaa catttgaagt cagggtaata tgaacattgc agtagttact
     3661 ggcatttcgt ctcctcagga tactttgatt ttccattttg gctcatgtgg gttgaaggag
     3721 ctgcacaccc cacctcacag gaacacacat tattgtcatt gtgaatagtc tatcagtcgt
     3781 cttttacaca gggcccttat atttggactg aaggaatagt gctgacaaaa gaaatcattt
     3841 ttctagtcct tttgccttta ctttgtgtgg cacttctgag gaacttgagg gatttgaatt
     3901 tcaaacttga atttgtataa gttctttata atgcccaaag atagaacacc ctgattccaa
     3961 agtacagcca ttatttcagt cctatcatgc ccaatttaaa gcttcagcaa ccgccttttg
     4021 tggaatccat agttgggctg gtacctttct ttgcagccag ccatactaag gtgagcttgt
     4081 gatagagggt tgtagctggg cctctgggga tctgtacttg acattttagg ctttctgtac
     4141 gccagtggaa gaaagcaaac gctggcgtta ggacctccag tgttgtgagc tcttgtttat
     4201 ccatataagc agctggaagg cgaggttgca gctttggtta taaaaagtat cactcacagt
     4261 gcttccaaag ggaagcagga aagatttgcc acgatacggc aagtgtgtga ttagaaagag
     4321 aagtcactta ttctctcttc tcctttctcc ccctgctggc ctgtttcctc tctcatcttt
     4381 ctagcctctc cttccctttt ccccttaaat ggctcttttg gtcttaagct actagtcagg
     4441 taaccctttg tgtttcatat catctacttt ccccgttgat ttaaaataga tttcagataa
     4501 atattttact ggcattttta gcaatgccaa tggtattttt tttagcaatg ccaatggtat
     4561 ttgagagaac aattagaaag ttttctttct tattgcaagg attgcctaaa cacttgtttg
     4621 aagtcacaga tggcactgga gggggccaag atgagctgac atctgatatt tctgcttttt
     4681 ttttttggcc gtttcacatt tgtctcatgt ggacagacac acacttgggt aaccaccata
     4741 cagatggaaa tcaggacatg tgggatttgg ctgaaccaga ggtccccaaa cattgcctgg
     4801 atcatttagt accccaggtg tggccacccc aggacttcat gtgctaaaat tgcgtcccag
     4861 tataagccag ctggtcactg tatatatagt atcaaggcaa cttgtagcct tagaaagcat
     4921 gacttttgat ttttaccttg tggatttaga cataaccaac ttaaatcttt tccctacata
     4981 gtgagcatag aggatgtggc aggtaaatag aaaggtttag caaaaggaga cgtttatgtt
     5041 tcaatagtta gtttcaacat ttctttttac aaaatccttt tctggagacg tctaagaaca
     5101 aacaatgatc ctaactttaa aattggaaga attgaacagt gctttttaaa aaaaaatata
     5161 ttagtccttt ctgcctacct gtgtgagagc ggtgcttcac ttgagcattt aagcaggagt
     5221 tgggtcctag tgcactaatc actttactca ggtgtctgtc cctttccagt ttacagaaga
     5281 gccttaacta ttatctcctg agcttcttag gataggtaaa gcagtccggc tccctactgg
     5341 catctccaac ttataagtaa ggaagcttag gctcagagca gttttgtttc ttgtctgtat
     5401 cacaaagctg tagaaatgga atccctactt tccctgaaac ccgcccctag atgttccttg
     5461 aagtgtgtca ttttcttcat aagaaagtcc ttccttgctg tttctattca tagatcattt
     5521 taaaaatcag tctgaagaag tgtgcttcac tttagcagat gaacaaaagc aaagcatttt
     5581 ctgattaagg tcacttagca tatgagtcct gcagtagcct tgctttctta gcttggtttt
     5641 aaatgaattg tttggagaga gattgttttc agtgttaaac agatgcacaa aagttgtctg
     5701 attataggtg aggatgctgc acctggagaa tgggagtaag gttgaaaagt tggcttaaaa
     5761 taattagcct cttgtgtttt tgttaagaga tgccatgttc aatagaattt aatttcttta
     5821 tacttcccgt gctgtcagct tttaaaatat aattctttag tgaaaaggag caaatatcca
     5881 ttcagagtgt tgatctgtca ggaacagggg tagccagagg gaaaagaaag tagaggggtg
     5941 actgtctata ccctgaagtg tgggtaagtg ttattttgtt tggagctgcg agctaagatt
     6001 tcttttaagg catgcaaatg gtaaagttgt gatttgtcaa ctgcacgctg tttctttagg
     6061 cactgatgta tgaaatcctg aacgaattct ccaatgaaca tactgctaat tgcttctcca
     6121 cctgctctcc aacctcccct caccccaccc cctccactct caattcagcc tataagtgtc
     6181 cgtcattgga gatggatggt gacacatgca gtaatagcaa ttcataaaag gcagttccag
     6241 cccttgtctt caaggctcct ggatttccca ctgcctgctt ttgtgtaagt gaagtggatg
     6301 gaagtgctac tggcatcaga atccacctcc ccgtgctccg gcgctagagc tcagttgctc
     6361 ggctggagct gagcttaaca gaagcatcgg atctgagcag aattgtagca gcagtgattt
     6421 tctcccccct ccatgggggg tgggttaggg atagtgtgta gtgggggctt aggttgtttt
     6481 agcttttctt tttgaggaca gagacggtcg ggagagaata actcccggca ggatacaacg
     6541 tgaaacagtt ccctgaagag tgtaacaatg ttcctggtac agtatacagg attgaatcag
     6601 ctgccctttg accctgccaa caacaacgaa cccctgcagt ttggtagtgc cagtggccct
     6661 ctggtcccag aaggcctcat tgagaatgga ggggaatcaa gcaagaaaag aaagagaaca
     6721 aatgctcctt cagctgataa tactagaact ctgaatgtag attctgctgc aatgacgcta
     6781 cctgtatctg atccaactgc atgggccaca gcaatgaata atcttggaat ggcgcctctg
     6841 ggaattgctg gacaaccaat tttacctgaa tttgatcccg cccttggaat gatgactgga
     6901 ataccaccaa taactccaat gatgcctggt ttgggaatag tacctccacc aattcctcca
     6961 gatatgcctg tagtaaagga gatcatacac tgcaaaagct gcacgctctt ccctcccaac
     7021 ccaaatctcc cgccacctgc aacacgagaa agaccaccag gctgtaagac tgtatttgtg
     7081 ggtggcctgc ctgaaaatgg gacagagcag atcattgtgg aagtgtttga gcagtgtgga
     7141 gagatcattg ctatccggaa gagcaaaaag aacttctgtc acattcgctt tgctgaggag
     7201 tacatggtgg acaaagccct ctatctgtct ggttacagaa ttcgcctggg ctctagtact
     7261 gacaagaagg acacaggccg gctccatgtt gactttgccc aggctcggga tgacttatac
     7321 gaatgggagt gtaaacagcg tatgctagca agagaggagc ggcaccgtag acggatggaa
     7381 gaagaaagaa tgcgtccacc atccccaccc ccagtggtcc actattcaga tcatgaatgc
     7441 agcattgttg ctgaaaaact aaaagatgat tccaaattct cagaagctgt gcagactttg
     7501 ctcacctgga tagagagggg ggaggtgaac cgccgcagtg ccaaccactt ctactcgatg
     7561 atccagtcag ccaacagcca tgtccgccga ctagtgaatg agaaagctgc ccacgaaaaa
     7621 gaaatggagg aagcaaaaga gaagttcaag caggcccttt ctggaattct cattcagttt
     7681 gagcagatag tagctgtgta ccattccgct tccaaacaga aggcatggga ccacttcaca
     7741 aaagcacaac gtaaaaacat cagcgtttgg tgcaaacaag ctgaggaaat tcgcaacatt
     7801 cataatgatg aattaatggg aatcaggaga gaagaagaaa tggaaatgtc tgatgatgaa
     7861 atagaagaga caacagaaac aaaagaaaca gaagaatcag ccttagtgtc acaggctgaa
     7921 gctctgaagg aggaaaacga tagcctccgt tggcagctgg atgcctaccg gaatgaggta
     7981 gaactgctca agcaggaaca aggcaaggct cacagggagg atgacccaaa caaggagcag
     8041 cagctgaaac ttctgcagca agccctacag gggatgcagc agcatctgct caaagtccaa
     8101 gaggaataca aaaagaaaga agctgaactt gacagaatca aagacgacaa gttacaggtg
     8161 gaaaaactgt tggaaaatct tcatgaaaag caggaaaact gtacttcaag actgtgtgca
     8221 tcaagccaag aaagtgacca ccctcttgag aaggccataa tcggcaaccc tgtcaaatcg
     8281 gaacgtgagg cactgctagt ggggatcatc tccacattcc ttcacgtgca cccatttgga
     8341 gcaagcattg aatacatctg ttcctacttg aatcgtcttg ataataagat ctgcaccagt
     8401 gatgtggaat ctctcatgag tagactccaa cataccttca ggcaggaaat gaccggagtt
     8461 ggagccagcc tagagaagag atggaaattc tgtggttttg aaggcttgaa gctgacctga
     8521 agctctttga ctaataattt gggatcctgg aaaaaaatgc gtgctggaca agcttaggat
     8581 gtgatttttt tttttattct cagtggtttt caagaggaca ttgctttcaa tttgtcaatt
     8641 cattcctgaa tatctttcaa cttaaaataa ggatcctaga acagcatctc aagctacagg
     8701 tcctaaaaga tattgcctca aaccacaagt gctgtaactt cctcctattt ctggcaattg
     8761 gttgacttct cttaagtaat agtgaaaaat tcctgagact aaagagtatt tggcgtgtgt
     8821 tcagtgttgt actactgttg tagaccttgt actttgtcag cgctgttaac tgcaatgttt
     8881 tgatgatctg taagtgcttt gtgtttccag atttctctcc acatgttgct actggtaaaa
     8941 ggagtgagag cattgctagg accccctata actgccattg tcttctccat ctgcagtaaa
     9001 cactaactga ataatccatc agtgtcttct ataaggtgct tcaccagttc acctttgaaa
     9061 taaaaaagca tgaactgtgg ctttttgtaa aaatactgtg aaccaaaagt tgacaaacgt
     9121 tccaaagtta ttttctctaa tagataaaag gtctatctca gaattttaaa acaagaaatc
     9181 tagatggact catggaaagt ctccagtata actaccgtgt ctgtgctttt cagaattact
     9241 tgtaaatagt ctgcttttaa aagagggcat gtttagtttt ctatgaatta aaatgcagtc
     9301 aggcgtgggc acatgtgtgc tcacattggc agaagggatt tattttaata gtccttccta
     9361 ctgtctgttg gtccattttt tcctgctgtt agtgtgttga attacaaact gtgtactgct
     9421 gtaaatgctg tttactttgt gctggatgtt tgtaaacaac tgatgtgagt attgaaagta
     9481 aagaactaat gaataaatga
//
