LOCUS       NM_012949               1457 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus enolase 3 (Eno3), mRNA.
ACCESSION   NM_012949
VERSION     NM_012949.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Chen,S., Lu,F.F., Seeman,P. and Liu,F.
  TITLE     Quantitative proteomic analysis of human substantia nigra in
            Alzheimer's disease, Huntington's disease and Multiple sclerosis
  JOURNAL   Neurochem Res 37 (12), 2805-2813 (2012)
   PUBMED   22926577
REFERENCE   2  (bases 1 to 1457)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   3  (bases 1 to 1457)
  AUTHORS   Uys,G.M., Ramburan,A., Loos,B., Kinnear,C.J., Korkie,L.J.,
            Mouton,J., Riedemann,J. and Moolman-Smook,J.C.
  TITLE     Myomegalin is a novel A-kinase anchoring protein involved in the
            phosphorylation of cardiac myosin binding protein C
  JOURNAL   BMC Cell Biol 12, 18 (2011)
   PUBMED   21569246
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1457)
  AUTHORS   Obermajer,N., Doljak,B., Jamnik,P., Fonovic,U.P. and Kos,J.
  TITLE     Cathepsin X cleaves the C-terminal dipeptide of alpha- and
            gamma-enolase and impairs survival and neuritogenesis of neuronal
            cells
  JOURNAL   Int J Biochem Cell Biol 41 (8-9), 1685-1696 (2009)
   PUBMED   19433310
REFERENCE   5  (bases 1 to 1457)
  AUTHORS   Seweryn,E., Bednarz-Misa,I.S., Danielewicz,R., Saczko,J.,
            Kulbacka,J., Dawiskiba,T. and Pietkiewicz,J.
  TITLE     Distribution of beta-enolase in normal and tumor rat cells
  JOURNAL   Folia Histochem Cytobiol 46 (4), 519-524 (2008)
   PUBMED   19141407
  REMARK    GeneRIF: The cellular localization of the muscle-specific isoform
            of the enolase in normal rat cardiomyocytes (H9c2, an embryonic rat
            heart-derived cell line) and a rat sarcoma (R1) cell line is
            reported here.
REFERENCE   6  (bases 1 to 1457)
  AUTHORS   Sun,H., Liu,J., Ding,F., Wang,X., Liu,M. and Gu,X.
  TITLE     Investigation of differentially expressed proteins in rat
            gastrocnemius muscle during denervation-reinnervation
  JOURNAL   J Muscle Res Cell Motil 27 (3-4), 241-250 (2006)
   PUBMED   16752196
REFERENCE   7  (bases 1 to 1457)
  AUTHORS   Keller,A., Rouzeau,J.D., Farhadian,F., Wisnewsky,C., Marotte,F.,
            Lamande,N., Samuel,J.L., Schwartz,K., Lazar,M. and Lucas,M.
  TITLE     Differential expression of alpha- and beta-enolase genes during rat
            heart development and hypertrophy
  JOURNAL   Am J Physiol 269 (6 Pt 2), H1843-H1851 (1995)
   PUBMED   8594891
REFERENCE   8  (bases 1 to 1457)
  AUTHORS   Sakimura,K., Kushiya,E., Ohshima-Ichimura,Y., Mitsui,H. and
            Takahashi,Y.
  TITLE     Structure and expression of rat muscle-specific enolase gene
  JOURNAL   FEBS Lett 277 (1-2), 78-82 (1990)
   PUBMED   2269373
REFERENCE   9  (bases 1 to 1457)
  AUTHORS   Ohshima,Y., Mitsui,H., Takayama,Y., Kushiya,E., Sakimura,K. and
            Takahashi,Y.
  TITLE     cDNA cloning and nucleotide sequence of rat muscle-specific enolase
            (beta beta enolase)
  JOURNAL   FEBS Lett 242 (2), 425-430 (1989)
   PUBMED   2914621
REFERENCE   10 (bases 1 to 1457)
  AUTHORS   Kato,K., Shimizu,A., Semba,R. and Satoh,T.
  TITLE     Tissue distribution, developmental profiles and effect of
            denervation of enolase isozymes in rat muscles
  JOURNAL   Biochim Biophys Acta 841 (1), 50-58 (1985)
   PUBMED   3893549
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY321069.1 and BC083566.1.
            
            On Mar 8, 2007 this sequence version replaced NM_012949.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ215526.1, Y00979.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                DY321069.1         1-13
            14-1457             BC083566.1         1-1444
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1457
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /note="enolase 3"
                     /db_xref="GeneID:25438"
                     /db_xref="RGD:2555"
     exon            1..49
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            50..136
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1356
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /EC_number="4.2.1.11"
                     /note="muscle-specific enolase; skeletal muscle enolase;
                     2-phospho-D-glycerate hydro-lyase; Muscle specific enolase
                     (beta beta enolose) (two splicing products); enolase 3,
                     beta, muscle"
                     /codon_start=1
                     /product="beta-enolase"
                     /protein_id="NP_037081.2"
                     /db_xref="GeneID:25438"
                     /db_xref="RGD:2555"
                     /translation="MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIY
                     EALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTEN
                     KSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAG
                     NKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNIL
                     ENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKL
                     GELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEK
                     KACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQ
                     IKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK"
     exon            137..232
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            233..291
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            292..361
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            362..495
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            496..718
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            719..916
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1118
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1227
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1286
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1435
                     /gene="Eno3"
                     /gene_synonym="BBE; MSE"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagctgctac ctaggcactc tactcaaagt tccaaagaag acattacagc catggccatg
       61 caaaaaatct ttgcccgaga aatcctggac tccaggggca accccacagt ggaggtggac
      121 ctgcacacag ccaagggtcg attccgagcg gctgtgccaa gcggagcttc cacgggtatc
      181 tatgaagcac tggagctacg agatggagac aaatcacgat acctggggaa aggagtgctg
      241 aaggctgtgg agcacatcaa caagactctc ggccctgctc tgctggaaaa gaaactaagt
      301 gttgtggatc aagaaaaagt tgacaaattt atgattgagc tggacggaac cgagaataag
      361 tccaagtttg gggccaatgc catcctgggt gtgtccctgg ctgtttgtaa ggctggagca
      421 gctgagaaag gggtccctct ctaccgacac attgcagacc tcgcagggaa tcccgacctt
      481 gtacttcccg tgcctgcctt caatgtgatc aacgggggct ctcatgctgg aaacaagttg
      541 gccatgcagg agttcatgat tctgccagtg ggagccagct ctttcaagga agccatgcgc
      601 attggcgctg aggtctacca ccacctcaag ggggtcatca aagccaagta tgggaaggat
      661 gccaccaatg tgggggacga gggtggcttt gcacccaaca tcctggagaa caatgaggcc
      721 ctggaactac taaagacagc cattcaggca gctggttacc cagacaaggt ggtgattggc
      781 atggatgtgg cagcatctga attctatcgc aatgggaagt atgatctgga cttcaagtca
      841 cctgatgatc ctgcgaggca catcagtggg gagaagctcg gggagctgta caagtccttc
      901 atcaagaact atcccgtggt ctccattgaa gacccctttg accaggatga ctgggcaaca
      961 tggacctcat tcctctctgg ggtggacatc cagattgtgg gagatgacct gacagtcacc
     1021 aaccccaaga ggattgctca ggctgttgag aagaaggcct gcaattgcct gctgctgaag
     1081 gtcaaccaga tcggctctgt gacagaatcc atccaggcct gtaaactggc acagtctaat
     1141 ggctggggag tgatggtgag ccaccgctct ggggagaccg aagacacttt cattgctgat
     1201 cttgtggtgg gactctgcac aggacagatc aagactggtg ctccctgccg ttcagagcgt
     1261 ctggcaaaat acaaccagct tatgaggatt gaggaggctc tcggagacaa agctgtcttt
     1321 gctggacgaa agttccgtaa tccaaaggcc aaatgagaag ctggagattc caggattcca
     1381 caggacagac acaggccttc aagcccttct cccagaaata aacactgcca aacaaaaaaa
     1441 aaaaaaaaaa aaaaaaa
//
