LOCUS       NM_001400843            5756 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus EMSY transcriptional repressor, BRCA2 interacting
            (Emsy), mRNA.
ACCESSION   NM_001400843 XM_006229813
VERSION     NM_001400843.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5756)
  AUTHORS   Ekblad,C.M., Chavali,G.B., Basu,B.P., Freund,S.M., Veprintsev,D.,
            Hughes-Davies,L., Kouzarides,T., Doherty,A.J. and Itzhaki,L.S.
  TITLE     Binding of EMSY to HP1beta: implications for recruitment of HP1beta
            and BS69
  JOURNAL   EMBO Rep 6 (7), 675-680 (2005)
   PUBMED   15947784
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 28, 2022 this sequence version replaced XM_006229813.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.1797189.1,
                                           SRR26360194.1571648.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               JAXUCZ010000001.1  162364604-162364707 c
            105-213             JAXUCZ010000001.1  162362902-162363010 c
            214-313             JAXUCZ010000001.1  162356417-162356516 c
            314-388             JAXUCZ010000001.1  162355046-162355120 c
            389-430             JAXUCZ010000001.1  162353811-162353852 c
            431-606             JAXUCZ010000001.1  162350236-162350411 c
            607-866             JAXUCZ010000001.1  162346496-162346755 c
            867-1143            JAXUCZ010000001.1  162338872-162339148 c
            1144-1461           JAXUCZ010000001.1  162335229-162335546 c
            1462-1611           JAXUCZ010000001.1  162330031-162330180 c
            1612-1782           JAXUCZ010000001.1  162327957-162328127 c
            1783-1919           JAXUCZ010000001.1  162321117-162321253 c
            1920-2093           JAXUCZ010000001.1  162318490-162318663 c
            2094-2292           JAXUCZ010000001.1  162316230-162316428 c
            2293-2457           JAXUCZ010000001.1  162308249-162308413 c
            2458-2613           JAXUCZ010000001.1  162306332-162306487 c
            2614-2765           JAXUCZ010000001.1  162302818-162302969 c
            2766-3329           JAXUCZ010000001.1  162300853-162301416 c
            3330-3809           JAXUCZ010000001.1  162299434-162299913 c
            3810-5756           JAXUCZ010000001.1  162295169-162297115 c
FEATURES             Location/Qualifiers
     source          1..5756
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..5756
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /note="EMSY transcriptional repressor, BRCA2 interacting"
                     /db_xref="GeneID:361607"
                     /db_xref="RGD:1310712"
     exon            1..104
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            105..213
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..4004
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /note="EMSY BRCA2-interacting transcriptional repressor"
                     /codon_start=1
                     /product="BRCA2-interacting transcriptional repressor
                     EMSY"
                     /protein_id="NP_001387772.1"
                     /db_xref="GeneID:361607"
                     /db_xref="RGD:1310712"
                     /translation="MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKE
                     KKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHKMNLSLYLGERPSYSMSGPNS
                     SSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAVQHNASLPVPAETASKEGVSCSD
                     EDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPP
                     HMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVI
                     ASTTQKPPVVITASQASLVTSSSNGNSNSTSSSISSTVAVTAVVSSTPSVVMSTVAQG
                     VSTSAIKVASTRLPSPKSLVSGPTQILAQFPKQHQQSPKQQLQQVPPQTPQPGAQPSS
                     VSQQQQQQQQQQQQQQQQQQQQQQQQQPQHSPLPPGIKPTIQIKQESGVKIITQQVQP
                     SKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSLGRVA
                     TTPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVV
                     QKTTGKGTTIQGLPGKNVVTTLLNAGGEKTLQTVPTGAKPAIITATRPITKMIVTQPK
                     GIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASR
                     VAEAGNSSAQEGKEEPQGYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAME
                     TSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQ
                     EKRHSPESPSIAVVESELVAEYITTVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVV
                     VKSIPASSPGAVTHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSAL
                     TQSQSTKQQKLSQPQLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLTQMPQLSVRH
                     QKLTPLQQEQAQPKPDAQHTQHTVVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQ
                     QAPNQPKIYVQPQAPQSQMALPTSSEKQPASQVEQPIITQGSSVTKITFEGRQPPTVT
                     KITGGSSVPKLTSPVTSISPIQASEKTAVSDILQMSLMEAQIDTNVEHMVVDPPKKAL
                     ATSVLTGEAGALPSTHVVVAGMTKCRESCSSPSAVGPPLTTRKVEAAGVPTTGQFMRI
                     QNVGQKKAEESPTEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDDETAM
                     EQDVDSSTEDGTEPSPSQSAVERS"
     exon            214..313
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            314..388
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            389..430
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            431..606
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            607..866
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1143
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1461
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1611
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1782
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1919
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            1920..2093
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            2094..2292
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            2293..2457
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            2458..2613
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            2614..2765
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            2766..3329
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            3330..3809
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
     exon            3810..5756
                     /gene="Emsy"
                     /gene_synonym="RGD1310712"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcgccatct tgccccttct gaggcaccgc aaacaaacct aattcctggt gtcccctagt
       61 cttggcggag gagcctttta gatgagcccc gaaaggccgg gcagtgagaa caagctcttt
      121 ggggctacca aacagaagca ccaatgcctg ttgtgtggcc aacccttttg gatctcagca
      181 gggatgaatg caaacggatt cttcgaaaat tggaattgga ggcatatgct ggagttatca
      241 gtgcacttcg ggcacaaggg gacctcacca aggaaaagaa agatcttctt ggagaactct
      301 caaaagtcct tagcatctca acagagcgcc accgtgctga agttcggaga gcagtaaacg
      361 atgaacggtt aacaacaatt gcacataaaa tgaatttatc cttatatttg ggtgaaagac
      421 caagttacag tatgtctgga cctaatagtt cttcagagtg gtccatcgaa gggcgtagat
      481 tggtaccact gatgcccagg ctggttcccc agactgcctt cactgtgaca gcgaatgctg
      541 tggccaatgc agctgtccag cacaatgcat ctcttcctgt gcctgcagag acagcaagca
      601 aagaaggtgt tagctgctca gatgaagatg aaaaacccag aaaacgcagg cgaacaaact
      661 cttctagctc ctcccctgtt gtcctgaagg aagttccaaa ggctgttgtt ccggtctcaa
      721 agactatcac tgtgcccgtg agcggaagtc ccaagatgag caacattatg cagagcattg
      781 ccaactcctt accaccccac atgtcacctg tgaaaataac tttcaccaag ccatcaacac
      841 agacaacaaa caccacaaca cagaaggtga ttatagtgac cacatcaccg agttcaacat
      901 ttgtgcccaa cattctctcc aaatcccata actatgcagc agtcactaag cttgtaccaa
      961 catcagtcat tgcctccacc actcagaagc cacctgttgt tataactgca tcccaggcct
     1021 ctctggtcac cagtagcagc aatggcaaca gcaattctac gtcatcatct atttctagta
     1081 cagttgcagt aacagcagtg gtatcttcca caccatccgt ggtcatgtca acagtagcac
     1141 aaggtgtatc cacatcagca atcaaagtgg cgtcgacaag actcccttcc cccaaaagct
     1201 tagtgagcgg ccctacccag atcctcgcgc agtttcctaa gcagcatcag cagtctccga
     1261 agcagcagtt acagcaagtg ccaccacaga caccgcagcc aggggcccag ccttcctcag
     1321 tgtcgcagca gcagcagcag cagcagcagc agcaacaaca acaacagcag cagcagcagc
     1381 agcaacagca acagcaacag cctcagcact caccactgcc acctggtatc aaacccacca
     1441 tccagatcaa acaggagtca ggtgttaaaa tcatcacaca gcaggttcaa ccaagtaaaa
     1501 tcttacccaa accagtgact gcaactctac ccaccagtag caattcccca attatggtgg
     1561 ttagcagtaa tggtgcaatt atgacaacta aactggtaac tactcctacc ggtactcagg
     1621 caacctatac ccggccaaca gtgagcccat ctttaggtcg agtagccaca acccctggag
     1681 ctgcaaccta tgtgaaaact accagcggta gcatcattac tgtggtgccc aaatcattag
     1741 ctaccttggg aggcaagata atcagcagta atattgtttc tggaacaact accaaaatca
     1801 ctacaatccc aatgacttcc aagcccaatg tgattgttgt acaaaagact acaggaaaag
     1861 gaacgaccat tcaaggcctc cctggcaaaa acgttgtcac aacattgcta aatgctggag
     1921 gagaaaagac tcttcagaca gtgccaactg gagcaaagcc agctataatt actgctacac
     1981 gacccatcac caaaatgatt gtaacacagc ccaaaggaat aggctccaca gttcagccag
     2041 cagctaaaat catcccgaca aaaattgtct atgggcaaca agggaaaaca caggttctca
     2101 ttaaacccaa accagtgaca tttcaagcta cagttgttag tgaacaaaca aggcagctgg
     2161 taacagaaac attacagcaa gcatccaggg tagcagaggc cggtaattca tctgctcagg
     2221 aaggaaaaga agaaccacag ggctacacag acagtagttc ctcttctaca gagtcctccc
     2281 agagttccca agattcccag cctgtagttc atgtaattgc ttcccggcgt caggattggt
     2341 cagaacatga gattgcaatg gagactagcc ccaccataat atatcaggat gtatccagtg
     2401 aatcacaatc agctacttca acaatcaaag ccctgttaga actccaacag acaacagtaa
     2461 aggaaaaatt ggaatctaaa ccaagacaac ccactattga cttgagtcaa atggcagtac
     2521 ctattcagat gacccaggaa aagagacatt ctcctgagag tccgtccatt gctgtggtag
     2581 agtcagaact agttgctgag tacatcacca cggtcagcca tcgctcccaa ccccaacagc
     2641 cttcccagcc tcagcgaacc ctgctccaac atgttgctca gtcacagact gcgacacaga
     2701 cgtcagtggt agtcaagtcc atcccagcgt cttcccctgg agccgtcacc cacatcatgc
     2761 agcaggcatt aagcagtcac actgctttta ccaaacacag tgaggaactt ggaactgagg
     2821 agggtgaggt tgaggagatg gacacattgg atcctcagac aggtctgttt taccgatctg
     2881 ccctgacgca gtcacagtca actaaacagc aaaaacttag ccagccccag ctggaacaga
     2941 ctcagctgca ggtgaaaacc ctgcagtgct tccagaccaa acagaagcag accatccacc
     3001 tgcaggctga ccagctccag cacaaactca cacagatgcc tcagctctcc gtcaggcatc
     3061 agaaactgac tcctctccag caggaacaag cacagcccaa gccagatgca cagcacacac
     3121 agcataccgt ggtggccaaa gacaggcagc ttcctacctt aatggcacag cccccgcaga
     3181 ctgtagtaca ggttcttgcc gtaaaaacca cacagcagct tcctaaacta cagcaagctc
     3241 cgaaccaacc aaaaatctac gtgcaacccc aagctcccca gagccaaatg gcgctcccca
     3301 cttcatcaga gaaacagcct gcaagccagg tggagcagcc aattataacc caaggatcct
     3361 ctgttacaaa gataacattt gaggggcgcc agcctcccac agttacaaag ataactggtg
     3421 gcagttctgt tcctaagctg acgtcaccag ttacaagcat atctcccatt caggcctctg
     3481 agaagacagc agtgtcagac attttgcaaa tgtctttgat ggaagctcag attgatacaa
     3541 atgtagaaca tatggtagtg gatcccccaa agaaggctct agccaccagt gtgctcactg
     3601 gtgaggcagg agctctaccc tccacccatg tggtggtggc agggatgacg aaatgtagag
     3661 agtcctgttc aagtccatct gctgttggcc ctcccctaac gaccagaaaa gtggaagcag
     3721 caggagtgcc tacgacaggc cagttcatgc gtattcagaa tgtaggccaa aagaaagctg
     3781 aagagagccc aacagaaatt atcatccagg ccattcccca gtatgctatt ccctgtcact
     3841 ccagctccaa cgtggtggtg gagcccagcg ggcttcttga attgaacaac ttcaccagtc
     3901 agcagctaga cgacgatgag acagctatgg agcaagatgt agacagcagc acggaggatg
     3961 ggactgagcc cagcccctct cagagcgctg tagagcggtc ctagtgtgca gatgccacca
     4021 gagtgcactt tagagcctgc ttggttacct accacgtgtc cagggaaact tacaatttgt
     4081 tatggtaaaa gaaaaaagca ctttgctcat acttaggctg gggacctaga aacagtgttt
     4141 cactgagatg ttgctgcagg agcagcattt taacaggatt aaactcacag aggaatgtac
     4201 tttaaaaaaa aaaaatagaa gaaaaaaaaa agcaaaggaa gagatgcacc ccgtggaggc
     4261 ctggtctctt gttggtgctg ggcagtggac agtttgtctg cactgaagag acttcctgcg
     4321 agtggctctc ggctgctttc cactgagcaa atgccaccag agaacattaa gaggaaaaga
     4381 aaggagactg tgaagagttt gtatttttga aatgatgtat ctgaacagtt ttttaaaaat
     4441 cgtgttttgt ttttgcaaat ccctggaaat gttgatttgg ctaacatttt acatttgctc
     4501 agttcatgat tagtttatga atacctagga aagttctggc attaaagagt ccttgctgga
     4561 gggtaaacat cagattgttg accaggaagt atttggggta gcttgtacat gtgctccttg
     4621 gttgtatact aatttattgt ggagttccac acttgtctat ttatttaatg taaatgtttt
     4681 caagcaggct aaaatccctt ctcctacatg ttctgggaag ctggattgcc gggtctggcc
     4741 acctcccctt tctccccttt aagacgacgg atttgagaag gcttggtcag gaagcagagg
     4801 ggaagacatt tctagcccaa aggaaatgtt cagtggtgtt aatgaaagtg aactctgctc
     4861 gtttgatgct ttctcaacac ggaagttgca catccatgtt ggactaagac tttgaaaaca
     4921 actcttactt actcactttg gtttaaatcc ctttgaaatg tatgaaagtg ttcacttaca
     4981 attctaaatg taatgttttt aatctttact tttttagggc gcagtttgtt tacatgctgg
     5041 tttggtcttg tgattgctga cacaagtaga gtgaagggta agggatggga gggtaagaat
     5101 tttgacaagc tatggcaaag gaaactatac ttttcatttt taaaaaagtg taaatagaaa
     5161 aagtttttaa cggttttata tgaatttcac tataaataag cattttaaga ctgacaaatg
     5221 ttgaactgta tatacattta tcagcataac tgcccaattt ttggtgctga agtactgtaa
     5281 ttagaattta tcagtagcgt cctaattttg gcaactacac acggggagaa gctctgatgc
     5341 tgtagttaat aaactcacac tagctagtgt gacactgaaa gtctcagcag gagcacccct
     5401 gagacacttt gctcctggtg gcctctccat ttctactggg tgaaagtcac tcacccatag
     5461 gtggagctgt tggatagcat tttactgtac aaatatattt caaccacctt gtgactgtcc
     5521 tagctaagga aaaaattaac ttctcttggg tcataaacat ctttaagaat ctgattaaac
     5581 tatgaactct ctcaccaaaa aaatacacat gccagtaccc gtgttaagat ttttgcatac
     5641 aatttcaggg acttatgggc tcccaagacc atccatgtac cccaggttaa gccttctgtt
     5701 atggtcaatc cttacttgca gttgtaagtt ttattaaata aactatcttt tgaata
//
