LOCUS       NM_001003402            6540 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus EMAP like 5 (Eml5), mRNA.
ACCESSION   NM_001003402 XM_243280
VERSION     NM_001003402.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6540)
  AUTHORS   Takizawa,C., Minematsu,T., Nakagami,G., Kitamura,A., Koudounas,S.,
            Kunimitsu,M. and Sanada,H.
  TITLE     Expression levels of NPPB, ITGB6, CPNE4, EML5, and ITSN1 in fresh
            exudates swabbed from critically colonised and infected
            full-thickness wounds in rats
  JOURNAL   Int Wound J 20 (4), 1088-1097 (2023)
   PUBMED   36307995
  REMARK    GeneRIF: Expression levels of NPPB, ITGB6, CPNE4, EML5, and ITSN1
            in fresh exudates swabbed from critically colonised and infected
            full-thickness wounds in rats.
REFERENCE   2  (bases 1 to 6540)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 6540)
  AUTHORS   O'Connor,V., Houtman,S.H., De Zeeuw,C.I., Bliss,T.V. and
            French,P.J.
  TITLE     Eml5, a novel WD40 domain protein expressed in rat brain
  JOURNAL   Gene 336 (1), 127-137 (2004)
   PUBMED   15225882
  REMARK    GeneRIF: Eml5 may play a role in the regulation of cytoskeletal
            rearrangements during neuronal development and in adult brain.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Aug 30, 2012 this sequence version replaced NM_001003402.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-576               JAXUCZ010000006.1  123904963-123905538 c
            577-736             JAXUCZ010000006.1  123885726-123885885 c
            737-835             JAXUCZ010000006.1  123878053-123878151 c
            836-904             JAXUCZ010000006.1  123876899-123876967 c
            905-1090            JAXUCZ010000006.1  123872595-123872780 c
            1091-1226           JAXUCZ010000006.1  123870905-123871040 c
            1227-1428           JAXUCZ010000006.1  123869433-123869634 c
            1429-1566           JAXUCZ010000006.1  123867109-123867246 c
            1567-1823           JAXUCZ010000006.1  123863106-123863362 c
            1824-2036           JAXUCZ010000006.1  123859788-123860000 c
            2037-2204           JAXUCZ010000006.1  123856290-123856457 c
            2205-2311           JAXUCZ010000006.1  123855586-123855692 c
            2312-2430           JAXUCZ010000006.1  123855072-123855190 c
            2431-2617           JAXUCZ010000006.1  123853855-123854041 c
            2618-2723           JAXUCZ010000006.1  123847556-123847661 c
            2724-2817           JAXUCZ010000006.1  123845133-123845226 c
            2818-2918           JAXUCZ010000006.1  123843994-123844094 c
            2919-3121           JAXUCZ010000006.1  123829980-123830182 c
            3122-3233           JAXUCZ010000006.1  123828914-123829025 c
            3234-3361           JAXUCZ010000006.1  123827823-123827950 c
            3362-3503           JAXUCZ010000006.1  123823599-123823740 c
            3504-3656           JAXUCZ010000006.1  123818280-123818432 c
            3657-3788           JAXUCZ010000006.1  123817049-123817180 c
            3789-3877           JAXUCZ010000006.1  123815043-123815131 c
            3878-4054           JAXUCZ010000006.1  123814039-123814215 c
            4055-4256           JAXUCZ010000006.1  123811956-123812157 c
            4257-4383           JAXUCZ010000006.1  123811020-123811146 c
            4384-4398           JAXUCZ010000006.1  123808118-123808132 c
            4399-4407           JAXUCZ010000006.1  123806422-123806430 c
            4408-4486           JAXUCZ010000006.1  123803979-123804057 c
            4487-4616           JAXUCZ010000006.1  123802116-123802245 c
            4617-4715           JAXUCZ010000006.1  123799538-123799636 c
            4716-4736           JAXUCZ010000006.1  123795355-123795375 c
            4737-4910           JAXUCZ010000006.1  123789288-123789461 c
            4911-5119           JAXUCZ010000006.1  123787726-123787934 c
            5120-5277           JAXUCZ010000006.1  123785915-123786072 c
            5278-5392           JAXUCZ010000006.1  123783422-123783536 c
            5393-5581           JAXUCZ010000006.1  123781120-123781308 c
            5582-5754           JAXUCZ010000006.1  123780800-123780972 c
            5755-5917           JAXUCZ010000006.1  123778876-123779038 c
            5918-6021           JAXUCZ010000006.1  123778335-123778438 c
            6022-6175           JAXUCZ010000006.1  123777570-123777723 c
            6176-6276           JAXUCZ010000006.1  123776863-123776963 c
            6277-6540           JAXUCZ010000006.1  123776368-123776631 c
FEATURES             Location/Qualifiers
     source          1..6540
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..6540
                     /gene="Eml5"
                     /note="EMAP like 5"
                     /db_xref="GeneID:444982"
                     /db_xref="RGD:1303275"
     exon            1..576
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     CDS             380..6313
                     /gene="Eml5"
                     /note="EMAP-5; EMAP-like protein 5; echinoderm microtubule
                     associated protein like 5"
                     /codon_start=1
                     /product="echinoderm microtubule-associated protein-like
                     5"
                     /protein_id="NP_001003402.2"
                     /db_xref="GeneID:444982"
                     /db_xref="RGD:1303275"
                     /translation="MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVG
                     VVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLK
                     DVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIFDISWDL
                     YQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNG
                     DIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLTFKPITVIDLRE
                     TEQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVH
                     PTKPLAVTGSDDRSVRIWSLVDHALIARCNMDEPIRCAAVNADGVHLALGMKDGSLTV
                     LRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGS
                     LSFITHLDWSSDSKYLQTNDGSGKRLLYKMPGGKEVTSKEEVKGMHWASWTCVAGLEV
                     NGIWPKYSDINDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHV
                     TNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLTESNSDESDSDLS
                     DVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFI
                     HGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKD
                     YVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGIDDSHTI
                     VLWDWKKGEKLSVARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGY
                     VGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEK
                     GFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHIL
                     VGTKNGEILEVDKSGPVTLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPS
                     HCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDVISDI
                     QFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGA
                     KEQLFFEAPRGKKQTIPSVEVEKISWATWTSVLGLCCEGIWPIIGEVTDVTASCLTSD
                     KMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMS
                     LMVWTSEVERHREKKNCDSEESDTDSEEDGGYDSDVTRENEISYTIRALSTNIRPMFG
                     VKPHLQQKEPSVDERQGVVRGSRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFG
                     YRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKF
                     INIVATGQVGDSADMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLS
                     VGLDPEHTVTIWRWQEGAKIASRGGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAG
                     RALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHILCRVVARAHN
                     GPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVC
                     RGKGKILVGTRNSEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTV
                     RLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDR
                     RCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADS
                     RHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADV
                     TCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVV
                     SAGGDDCSLLVWKCVHTPH"
     exon            577..736
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            737..835
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            836..904
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1090
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1226
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1428
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1566
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1823
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            1824..2036
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2037..2204
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..2311
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2430
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2431..2617
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2618..2723
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2817
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2818..2918
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            2919..3121
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            3122..3233
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            3234..3361
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            3362..3503
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            3504..3656
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            3657..3788
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            3789..3877
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            3878..4054
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4055..4256
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4257..4383
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4384..4398
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4399..4407
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4408..4486
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4487..4616
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4617..4715
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4716..4736
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4737..4910
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            4911..5119
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            5120..5277
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            5278..5392
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            5393..5581
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            5582..5754
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            5755..5917
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            5918..6021
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            6022..6175
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            6176..6276
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
     exon            6277..6540
                     /gene="Eml5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgagcgcc gcaggtgacc cgggcaggga gtccggtgcg cggagccggc tgagaaggag
       61 caggctggag gcgggtcccc gtcccccctc ttagcttggt tgtctcctag cctaggcact
      121 gggctgaggg gacacggcga gctcccagac gcgcgaggct cccggacggc cggcggcgct
      181 cgcggccctc agcatgtttg gtgaggcgag gcttttcctc ccgcccgtgg gctgaggcga
      241 cgacggcggc cacgcaagcg agatgcacct gccgggctcg gcttagagga gcgtcccggc
      301 cgccagcggg agagctttcg tcacccggcc ccggcggcga tcgcgggccc gagccgcagc
      361 gacgggtggg cgcacggaca tggcggctcg gagcgccccg agctgccacc tgcggctcga
      421 gtgggtgtac ggctaccggg gccaccagtg ccgcaacaac ctctactaca ccgcggccaa
      481 ggagatcgtg tacttcgtgg cgggggtcgg cgtcgtgtat agcccgcggg agcatcggca
      541 gaagttctac cgcggccaca gcgacgacat catcagtctc gcactgcatc ctgagcgcgt
      601 gttggtagca acaggacaag ttgggaaaga gccttacatc tgtgtttggg attcttacac
      661 ggtccagact gtgtcggttc tgaaggacgt tcatacacat ggtatagctt gtttagcatt
      721 tgacttggat ggacagcgct tagtttcagt tggactcgat tcaaagaatg cagtttgtgt
      781 ttgggactgg aaaaggggga aaatgctgtc tatggctcct ggtcacacag acagaatatt
      841 tgatatttct tgggatttgt accagccaaa taagctcgtc agctgcggtg ttaaacacat
      901 caagttctgg agtttgtgtg gaaatgctct gaccccaaaa cgaggagttt ttggtaaaac
      961 aggtgacctt cagacaatat tgtgcctagc ctgtgctcgg gacgaattaa catattctgg
     1021 tgcactcaat ggcgatatat atgtttggaa aggaatcaat cttatacgaa caatacaagg
     1081 agcccatact gcagggattt ttagtatgaa tgcttgtgaa gaaggctttg ctactggagg
     1141 cagagatggc tgtattcgtc tttgggattt aacttttaaa ccaattactg tgattgatct
     1201 cagggaaaca gaacagggat acaaaggttt atctgtgagg agtgtttgtt ggcgaggtga
     1261 ccacatttta gtgggaacac aggacagtga aatttttgaa attgttgtgc atgaaagaaa
     1321 taaacctttc ctaattatgc aagggcattg cgaaggtgaa ctttgggcgc ttgctgttca
     1381 ccctactaag cctttggctg taaccggaag tgatgatcgt tcagtcagga tttggagcct
     1441 tgtagatcat gctctaatag cgagatgtaa tatggacgag ccaatccgat gtgccgctgt
     1501 caatgccgac ggagtccacc tcgcccttgg aatgaaggat gggtcactca ctgtccttag
     1561 agtgagagat atgactgaag ttgtacatat taaagacagg aaagaagcaa tccatgagct
     1621 gaaatattct ccagatggca cttaccttgc ggttggctgc aatgacagct cagttgacat
     1681 ctatggagtt gctcagcgtt acaaaaaagt gggtgaatgc gtcggttccc ttagcttcat
     1741 cactcatttg gattggtctt cagacagtaa atacttacag acaaatgacg gcagtgggaa
     1801 acgacttctc tacaagatgc caggaggaaa ggaagtgaca agcaaagaag aagtaaaagg
     1861 catgcactgg gcttcatgga cgtgtgttgc aggccttgaa gtcaatggaa tttggcccaa
     1921 gtattctgac atcaatgata taaactcagt agatggaaac tatgttggcc aggttttagt
     1981 tacagctgat gactatggag ttgtaaaatt attccgatat ccatgtttaa gaaaaggggc
     2041 caagttcaga aaatacattg gccattcagc tcatgtaact aatgtcagat ggtcacatga
     2101 ttaccagtgg gttatttcta ttggtggagc ggatcactct gtctttcagt ggaaatttat
     2161 tcctgagaga aaattaaaag atgctcttca catagcaccg caagaaagtc tgactgagtc
     2221 caacagcgat gaatcagatt cagatctgtc tgatgttccg gaactagatt ctgagattga
     2281 gcaagagaca cagcttactt accaccggca ggtttacaaa gaagatctac ctcaactcaa
     2341 agaacaatgc aaagagaagc agaaaagtgc tacttctaaa cgaagagaac gtgctccagg
     2401 aaatagtatt cgattacact tcattcatgg ttacagaggt tatgactgtc gaagcaatct
     2461 tttctacact caaattggtg aaattgtgta ccatgtagca gcagtgggtg tcatatataa
     2521 tagacaacag aacactcagc gtttttactt gggtcatgat gatgatatcc tgtgtctggc
     2581 tattcatcct ttgaaagact atgtggcaac aggccaggtt ggtagagatc cctcaattca
     2641 cgtctgggac acagaaacca ttaaaccatt gtctatatta aagggctacc accaatatgg
     2701 catctgtgct gtggatttct cagctgatgg gaaacgccta gcttcagttg gaatagatga
     2761 cagccacacc attgtattgt gggattggaa gaaaggggag aaactttcag tggcaagagg
     2821 cagtaaagat aagatttttg ttgtgaaaat gaacccctat gtgcctgata aactaattac
     2881 agctgggatt aaacacatga aattttggcg tagagcaggg ggagggctaa ttggaagaaa
     2941 aggctacgtc ggcactctgg ggaaaaatga cacaatgatg tgtgcagtgt atggatggac
     3001 tgaagagatg gctttttctg gaacatccac aggagatgta tgcatctgga gagatgtctt
     3061 tcttgtaaaa acagttaaag cccatgatgg gcccgtgttc agtatgcacg cattggagaa
     3121 aggatttgta actggaggaa aagatggcgt ggtagccctt tgggatgatt cctttgaaag
     3181 atgtctcaag acttatgcta taaaaagagc tgatttagcc ccaggatcta aaggtctgct
     3241 cttggaagat aacccatcta tacgtgccat atcattagga catggtcata ttctggttgg
     3301 cacaaagaac ggtgagatat tggaagtgga taaaagtggc ccagtcactc tgctggtcca
     3361 gggacacatg gaaggagagg tgtggggttt ggccacacat ccttatctgc ccatctgtgc
     3421 tactgtaagt gatgataaga ccttaagaat atgggatctc tctcctagtc attgtatgtt
     3481 ggcagtccgg aaactgaaga agggtgggcg gtgctgctgc ttttcccctg atggcaaagc
     3541 tttggctgta ggactcaatg atggaagctt cttgatggcc aacgcagaca ctctagagga
     3601 tcttgtgtcc tttcaccaca gaaaagatgt tatttcagac atccagtttt cacctggttc
     3661 tgggaaatac ctcgctgtgg cgtcccatga cagcttcgtt gatatataca atgtgacaag
     3721 tagcaagcga gtgggagttt gcaaaggagc aacaagctac atcacccaca tcgactggga
     3781 cagcagagga aagcttttac aggtcaacac tggtgctaaa gaacagctat tcttcgaagc
     3841 tcccagaggg aaaaaacaaa ccatccccag tgtggaggtg gaaaaaatta gttgggcgac
     3901 atggacaagt gttcttggtt tatgttgtga gggaatttgg ccaataattg gagaagtcac
     3961 agatgtaacc gcctcttgcc tcaccagtga caaaatggtc ctagctacag gggatgactt
     4021 gggattcgtg aagctgttca gatacccagc taaaggaaaa tttggaaagt ttaagaagta
     4081 tgtggctcac agcacacacg tcacaaatgt tcgctggact tacgatgaca gcatgctggt
     4141 taccctggga ggagcagata tgtccttaat ggtatggaca agtgaagtgg agagacatcg
     4201 ggaaaagaag aactgtgaca gtgaagagtc tgatacagat tctgaagaag atggaggcta
     4261 tgacagcgat gttacaagag agaatgaaat tagctacacc atcagagcct tatcaactaa
     4321 tatccgccca atgtttggag tcaagcctca tttgcaacag aaagagccct cagttgatga
     4381 aagacagggg gtagtaagag gatccaggcc tccagtgagt agggccccac cacagcccga
     4441 gaaacttcag tcaaacaatg taggcaagaa gaagagaccc atagaggacc ttgtgttgga
     4501 gctcgctttt ggctatcggg gcagagactg caggaacaat gtgcactact taaatgacgg
     4561 tgatgatata atttatcaca ccgcctctgt tggaattctg cacaatgttg ccacagggac
     4621 tcagagtttt tatcaagagc ataatgatga tattctgtgc ctcactgtaa atcagcaccc
     4681 caagtttatc aacatagtgg caactggcca agtaggtgat tctgcagaca tgtcagctac
     4741 agccccatct gtccacatct gggatgcagt gaacaagcag acattgtcta tactaagatg
     4801 ctcccattca aagggcgtgt gttctgtcag cttcagtgct actgggaagc tgctgctgtc
     4861 tgtagggcta gacccagagc acactgttac catttggaga tggcaggaag gggccaaaat
     4921 tgccagcaga ggtgggcaca accaacgtat ttttgtagca gaatttcgac cagattcaga
     4981 tacccagttt gtctctgtgg gtataaagca cgtgaagttc tggaccctgg caggaagggc
     5041 tcttctcagc aaaaaggggc ttctgagcac cctggaggat gcccggatgc agacgatgct
     5101 cgctgttgca tttggtgcaa ataacttgac gtttacaggt accatcagtg gtgatgtctg
     5161 tgtgtggaaa gatcacatat tgtgtagagt ggtggctaga gcacacaatg ggcctgtgtt
     5221 tgccatgtac accaccctgc gagatggact gattgtgacc ggtggcaaag aaaggccgtc
     5281 aaaggaagga ggtgcggtta aactgtggga tcaggaactg cggcgatgcc gggccttcag
     5341 gcttgagacg ggacaagtca cagattgtgt tcggtctgtg tgcagaggca aaggcaagat
     5401 actagttgga acaaggaatt cggaaataat tgaagttggg gagaaaaatg cagcatgtaa
     5461 cattttagtt aatggtcatg tggatggacc aatctgggga ctagcaacac atccttccag
     5521 ggatttcttc ctttctgctg ctgaagatgg aacagtgaga ctctgggaca ttgctgataa
     5581 aaagatgcta aacaaagtga atttgggaca tgctgctcgg acagtatgtt acagccccga
     5641 aggcgacatg gtggctattg gaatgaaaaa tggagaattt attatattac ttgtgagttc
     5701 tctaaaaata tggggaaaga agagagacag gcgatgtgca atccatgata tcagatttag
     5761 tccagattcc cggtatttgg cagtgggttc cagtgagaac tcggtggact tttatgacct
     5821 gacattgggt cccaccctta acagaatcag ctactgcaaa gacattccaa gctttgtcat
     5881 tcagatggac ttctctgcag atagcagaca tctccaggtt tctagtggct gctataaacg
     5941 gcatgtctat gaagtgcctt caggaaaaca ccttgtggat catgctgcca ttgacaggat
     6001 cacgtgggct acctggacta gtattctagg tgatgaagtt atgggaatct ggtccagaca
     6061 tgctgagaag gcagatgtca cctgtgcctg tgtgtctcac tcaggaatca gccttgtgac
     6121 aggagatgac tttggcatgg ttaaattata tgactttcca tgcccagaaa aatttgcaaa
     6181 acacaagagg ttcttgggtc attcccctca tgtgacaaat attcgattta ccagtggtga
     6241 tcgacatgtt gtcagtgctg gaggcgatga ctgcagcttg cttgtctgga aatgtgtaca
     6301 cacgcctcat tgaaagttac gatgctgaga agactaaaca aatctcacct caagagagca
     6361 gttccacgtc ggaaaaacca aaaccaaact gtgtggtcaa gtggtgctaa ctgaagactg
     6421 tgacagggag ggatgtccag aatcatccac acagcagcag acagttcaaa atgcttgctg
     6481 tgcgtaccaa cccatagtcc acacactgcc agataattac actacaagga atgactgagc
//
