LOCUS       NM_001113785            1223 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ER membrane protein complex subunit 2 (Emc2),
            mRNA.
ACCESSION   NM_001113785 XM_001062644 XM_343234
VERSION     NM_001113785.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1223)
  AUTHORS   Christianson,J.C., Olzmann,J.A., Shaler,T.A., Sowa,M.E.,
            Bennett,E.J., Richter,C.M., Tyler,R.E., Greenblatt,E.J.,
            Harper,J.W. and Kopito,R.R.
  TITLE     Defining human ERAD networks through an integrative mapping
            strategy
  JOURNAL   Nat Cell Biol 14 (1), 93-105 (2011)
   PUBMED   22119785
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1223)
  AUTHORS   Hoja,M.R., Wahlestedt,C. and Hoog,C.
  TITLE     A visual intracellular classification strategy for uncharacterized
            human proteins
  JOURNAL   Exp Cell Res 259 (1), 239-246 (2000)
   PUBMED   10942595
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158805.1.
            
            On or before Jan 27, 2008 this sequence version replaced
            XM_001062644.1, XM_343234.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158805.1, FQ215024.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1223
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q31"
     gene            1..1223
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /note="ER membrane protein complex subunit 2"
                     /db_xref="GeneID:362905"
                     /db_xref="RGD:1310430"
     exon            1..64
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..918
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /note="tetratricopeptide repeat protein 35; TPR repeat
                     protein 35; tetratricopeptide repeat domain 35"
                     /codon_start=1
                     /product="ER membrane protein complex subunit 2"
                     /protein_id="NP_001107257.1"
                     /db_xref="GeneID:362905"
                     /db_xref="RGD:1310430"
                     /translation="MAKVTERYDVTWEEMRDKMRKWREENSRNSEQIMEVGEELINDY
                     ASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMER
                     YDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHE
                     LAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQA
                     LKLNNRNMRALFGLYMSASHIASNPKASAKMKKDNIRYAGWAANQINRAYQFAGRSKK
                     ETKSSLKAVEDMLETLQITQS"
     exon            65..178
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            179..243
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            244..329
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            330..387
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            388..473
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            474..533
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            534..615
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            616..726
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            727..831
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
     exon            832..1198
                     /gene="Emc2"
                     /gene_synonym="RGD1310430; Ttc35"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgctgcctc taggttctag gaagatggcg aaggtcactg agcgttacga tgtgacttgg
       61 gaagaaatgc gagataaaat gagaaaatgg cgagaagaaa attcaagaaa tagtgaacaa
      121 attatggaag ttggagaaga attaattaat gattatgcat ctaagcttgg ggacgacatt
      181 tggatcatat atgagcaggt gatgattgca gccctagact atggtcggga tgacttggca
      241 ttgttttgtc ttcaggagtt aagaagacaa ttccctggta gtcacagagt taagcggtta
      301 acgggaatgc ggtttgaagc tatggaaaga tatgatgatg ctatacaact gtatgatcgg
      361 attttgcaag aagatccaac taatactgct gccagaaagc gtaagattgc cattcgaaaa
      421 gcccagggga aaaatgtgga ggccattcgg gagctgaatg agtatctgga acagttcgtt
      481 ggagaccaag aagcctggca tgaacttgca gaactttata ttaatgagca tgactatgcc
      541 aaagcagcct tttgcttaga ggagctgatg atgacaaatc cacataacca cttgtactgt
      601 caacagtacg cagaggtcaa atacacccaa ggtggacttg aaaacctgga gctttcaaga
      661 aagtattttg cacaggcact gaaactcaac aacagaaaca tgagagctct gtttgggctt
      721 tacatgtctg caagtcatat tgcttctaat ccaaaagcaa gtgcaaagat gaaaaaagac
      781 aacatcagat atgctggttg ggctgctaat caaataaaca gggcttatca gtttgcaggt
      841 cgaagtaaga aggaaaccaa atcctctctt aaggcagttg aagacatgtt ggagacattg
      901 cagatcactc agtcttaagg tttcaggaac tctctgacgt tagatttcaa aactgcacag
      961 ttgaacttct tggcctgtga cttaatttac tgactgccta gtgctatttg tattctaatt
     1021 ttttctgaag gggtcattgt aaagaatgtg tctaaataaa cctcaacttg ccttgtgctg
     1081 ggcgtaagcg ggaagatgga ggtgtccgtg ggacagagat tgaagaccta ttgattgtat
     1141 ttccatcctc atcgatcacc ccacacctta ttaaataaac catgcttgag taaactcaaa
     1201 aaaaaaaaaa aaaaaaaaaa aaa
//
