LOCUS       NM_001108782            1303 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus elongator acetyltransferase complex subunit 6
            (Elp6), mRNA.
ACCESSION   NM_001108782 XM_001075724 XM_343489
VERSION     NM_001108782.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1303)
  AUTHORS   Close,P., Gillard,M., Ladang,A., Jiang,Z., Papuga,J., Hawkes,N.,
            Nguyen,L., Chapelle,J.P., Bouillenne,F., Svejstrup,J., Fillet,M.
            and Chariot,A.
  TITLE     DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and
            migration of melanoma cells as subunits of Elongator
  JOURNAL   J Biol Chem 287 (39), 32535-32545 (2012)
   PUBMED   22854966
REFERENCE   2  (bases 1 to 1303)
  AUTHORS   Bolukbasi,E., Vass,S., Cobbe,N., Nelson,B., Simossis,V.,
            Dunbar,D.R. and Heck,M.M.
  TITLE     Drosophila poly suggests a novel role for the Elongator complex in
            insulin receptor-target of rapamycin signalling
  JOURNAL   Open Biol 2 (1), 110031 (2012)
   PUBMED   22645656
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166773.1.
            
            On May 11, 2008 this sequence version replaced NM_001108782.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166773.1, EV770366.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1303
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1303
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /note="elongator acetyltransferase complex subunit 6"
                     /db_xref="GeneID:363150"
                     /db_xref="RGD:1305478"
     exon            1..76
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..823
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /note="UPF0405 protein C3orf75 homolog; elongator complex
                     protein 6 homolog; transmembrane protein 103"
                     /codon_start=1
                     /product="elongator complex protein 6"
                     /protein_id="NP_001102252.1"
                     /db_xref="GeneID:363150"
                     /db_xref="RGD:1305478"
                     /translation="MFPELNNLLSITPDRTEQGKLTLLCDAKTDGSFLVHHFLSFYLK
                     ANCKVCFVALVQSFSHYNIVGQKLGVSLTAARERGQLVFLEGLKSSVEVLFHSQEEPH
                     PLQFLREAGAGNLQSLYTFIQDTLKPADSGESPWKCPVLLVDNLSVLLSLGVGAVAVL
                     DFMQYCRATVCCELKGNVVALVHDTEGAEDEENNILLNGLSHQSHLILRTQGLATGFC
                     KDVHGQLSILWRRSSQPTAQRARSLTYQYKIQDKNVSFFAKGMSRAVL"
     exon            77..155
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /inference="alignment:Splign:2.1.0"
     exon            156..226
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /inference="alignment:Splign:2.1.0"
     exon            227..345
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /inference="alignment:Splign:2.1.0"
     exon            346..547
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /inference="alignment:Splign:2.1.0"
     exon            548..694
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /inference="alignment:Splign:2.1.0"
     exon            695..1230
                     /gene="Elp6"
                     /gene_synonym="RGD1305478; Tmem103"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcattttta tcccagttca taatgttccc ggaactcaac aaccttctca gcatcacccc
       61 agacaggacc gagcagggga aactgactct cctctgtgac gccaagacag acggcagctt
      121 ccttgtgcat cacttcctgt ccttctacct gaaagctaat tgtaaagtct gcttcgtggc
      181 acttgtccag tctttcagcc attacaatat tgtgggacag aaactgggcg tcagcttgac
      241 cgcagcgcgg gagcgagggc agcttgtgtt cctggagggc ctcaagtcct ccgtggaagt
      301 cctcttccac tctcaggagg agcctcaccc cctgcagttt ctcagggagg ctggtgcagg
      361 gaacctacag tcgctgtata cgtttataca ggacaccctg aagcccgcgg acagtgggga
      421 gtcgccatgg aagtgcccag tcctgttggt ggacaacctc agtgtgctgc tgagcctggg
      481 tgtgggggca gttgccgtgc tggatttcat gcagtactgc agggccacgg tgtgctgcga
      541 actgaaggga aatgtggtag ccctcgtgca cgacactgaa ggtgctgagg atgaagagaa
      601 taacatccta ctgaatggcc tcagtcatca aagtcacctg atcctgcgga ctcagggcct
      661 ggccaccgga ttctgcaagg acgtgcatgg gcagctgagc attctctgga ggaggtcgtc
      721 gcagcccaca gcccagcggg ctcgaagtct cacttaccaa tacaagatac aggataagaa
      781 tgtgtccttt tttgccaaag gaatgtctcg tgctgttctg tgacctaatt ccggacaacc
      841 gaagtgactt tggacagctg tgggtgtgga agataaagca cccggtggaa tgcgccctca
      901 gacctttgac tcactcttca ggcttcacca cagcagccgt gacccgggac gatggtgctg
      961 tgagcacctg ctttgtcccc agggctctgc tcaggaaaca cagtgaggaa ctgcgtgagg
     1021 ctcctgctga gagagactgc atggtgaacc ccagcagagc ggtcctttgg ggcatcccat
     1081 gtgacttcgg ccttacctgc ctatttttgg aggttgtgac attgagagcc acactgtggg
     1141 cagaaggagg cagtcaggaa gttgcctgaa tggcagccat actggctgac ggctaggacc
     1201 atgatgggtg gaataaagaa ggttcccaca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1261 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
