LOCUS       NM_001115047            1531 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus elongator acetyltransferase complex subunit 4
            (Elp4), mRNA.
ACCESSION   NM_001115047 XM_001079792
VERSION     NM_001115047.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Close P, Gillard M, Ladang A, Jiang Z, Papuga J, Hawkes N, Nguyen
            L, Chapelle JP, Bouillenne F, Svejstrup J, Fillet M and Chariot A.
  TITLE     DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and
            migration of melanoma cells as subunits of Elongator
  JOURNAL   J Biol Chem 287 (39), 32535-32545 (2012)
   PUBMED   22854966
REFERENCE   2  (bases 1 to 1531)
  AUTHORS   Kim JH, Lane WS and Reinberg D.
  TITLE     Human Elongator facilitates RNA polymerase II transcription through
            chromatin
  JOURNAL   Proc Natl Acad Sci U S A 99 (3), 1241-1246 (2002)
   PUBMED   11818576
REFERENCE   3  (bases 1 to 1531)
  AUTHORS   Hawkes NA, Otero G, Winkler GS, Marshall N, Dahmus ME, Krappmann D,
            Scheidereit C, Thomas CL, Schiavo G, Erdjument-Bromage H, Tempst P
            and Svejstrup JQ.
  TITLE     Purification and characterization of the human elongator complex
  JOURNAL   J Biol Chem 277 (4), 3047-3052 (2002)
   PUBMED   11714725
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158667.1.
            
            On Mar 12, 2008 this sequence version replaced NM_001115047.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158667.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q33"
     gene            1..1531
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /note="elongator acetyltransferase complex subunit 4"
                     /db_xref="GeneID:687694"
                     /db_xref="RGD:1566052"
     exon            1..224
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..1273
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /note="elongation protein 4 homolog"
                     /codon_start=1
                     /product="elongator complex protein 4"
                     /protein_id="NP_001108519.1"
                     /db_xref="GeneID:687694"
                     /db_xref="RGD:1566052"
                     /translation="MAAAATCGAGTLSSECVASEAGQSRTSSFQRRGKASGAPGGGPR
                     LLSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTLLLIEEDKYNIYSPLLFKYFL
                     AEGIVNGHTLLVASAKENPANILQELPAPLLDDNGKKELEDVHSAKPPEADANMKIAW
                     RYQLQPRMEVGPVLSSRFGHYYDVSRRIPQELLESSNWHGFFLPEHTPPGLKGEPCFL
                     SCGYMKLLQFFQNIIYTEGFDGANPQKKQKNILRIGIQNLGSPLWGDDICCKENSDNH
                     HRLTKFLYILRGLLRSSLSACIITMPAQLVQNKAITTRVRNLSDTVVGLESFIGSERE
                     TNPLYKDYHGLIHIRKIPRLNNLTCDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVG
                     RSSRQDLAPSTTLLGTGCSGMTGGKKRLDF"
     exon            225..260
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            261..382
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            383..511
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            512..651
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            652..736
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            737..925
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1034
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1141
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1508
                     /gene="Elp4"
                     /gene_synonym="RGD1566052"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caagatggcg gcggcagcca cctgcggcgc gggtaccctc agctccgaat gtgtggcttc
       61 cgaggcgggc cagagccgca cctctagctt ccagaggaga ggcaaggctt ctggggcccc
      121 cggagggggt ccccggctgc tgtccatcgc aggcacgcga ccgtcggtgc ggaatggaca
      181 actgctggtg tcaaccgggc tcccagccct ggaccagctt ttaggtggag gtttagctgt
      241 tggaacactt cttctgatcg aagaggataa atataatatc tattcgcctt tgctcttcaa
      301 gtatttcctg gcagaaggaa tcgtcaatgg acacactctg ttggttgcat ctgctaaaga
      361 aaatcctgcc aacattttac aggaactccc tgcaccacta cttgatgaca atggtaaaaa
      421 ggagcttgaa gatgtacaca gcgctaaacc cccagaggca gacgctaaca tgaagatagc
      481 ctggcggtac cagctacaac ccaggatgga ggttgggcca gtcttatcgt cacgatttgg
      541 tcactattat gatgtatcaa gaaggattcc tcaggagcta ctagagagtt cgaattggca
      601 tggattcttc cttccagaac acacccctcc aggtcttaaa ggagaaccct gctttttgtc
      661 ctgtggctac atgaagctgc ttcagttctt tcagaacatc atttatactg aaggatttga
      721 tggagctaat ccccagaaaa aacagaaaaa cattttaagg ataggaattc agaaccttgg
      781 ctcaccatta tggggagatg acatttgctg taaagaaaac agtgacaacc atcacaggct
      841 taccaagttc ctctacattc tccgtggcct tctaagatcc tcactgtcag cctgcatcat
      901 cacaatgcca gcacaacttg tccagaataa agcaattact acccgtgtga gaaatttgtc
      961 agatacagta gttggtctgg aatcttttat tggttcagag agagagacca acccattgta
     1021 taaggattat catggtctaa tccatatacg gaagattcct cggcttaata acttgacttg
     1081 tgatgaatcg gatgtcaaag acttagcttt taagttaaaa aggaagctgt tcaccattga
     1141 gcgactgcat ctgcctccag acttgtcaga cacagtgggc cgttcaagca gacaggacct
     1201 ggcaccatcc accactctgc tgggcacagg ctgtagcggg atgaccggag gcaagaagcg
     1261 cctggacttc tagggacgct ccttggccac cttgtgcgaa gttatctgac cctctaatct
     1321 ttgagaaaca cagggttaca aagtagagtc accattcttc agtttgggtt gtttcattat
     1381 ttgttttttt ctactagctt ctgtacaaaa ataaatatgg cagaaatgct gtcatttgac
     1441 atttagctgc tgttatgttt ttttaaatac taattaattt ttaaataaac accaaaaaat
     1501 acctaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
