LOCUS       NM_001034145            2762 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus elongator acetyltransferase complex subunit 2
            (Elp2), mRNA.
ACCESSION   NM_001034145 XM_003751750 XM_226098
VERSION     NM_001034145.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2762)
  AUTHORS   Close,P., Gillard,M., Ladang,A., Jiang,Z., Papuga,J., Hawkes,N.,
            Nguyen,L., Chapelle,J.P., Bouillenne,F., Svejstrup,J., Fillet,M.
            and Chariot,A.
  TITLE     DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and
            migration of melanoma cells as subunits of Elongator
  JOURNAL   J Biol Chem 287 (39), 32535-32545 (2012)
   PUBMED   22854966
REFERENCE   2  (bases 1 to 2762)
  AUTHORS   Hawkes,N.A., Otero,G., Winkler,G.S., Marshall,N., Dahmus,M.E.,
            Krappmann,D., Scheidereit,C., Thomas,C.L., Schiavo,G.,
            Erdjument-Bromage,H., Tempst,P. and Svejstrup,J.Q.
  TITLE     Purification and characterization of the human elongator complex
  JOURNAL   J Biol Chem 277 (4), 3047-3052 (2002)
   PUBMED   11714725
REFERENCE   3  (bases 1 to 2762)
  AUTHORS   Collum,R.G., Brutsaert,S., Lee,G. and Schindler,C.
  TITLE     A Stat3-interacting protein (StIP1) regulates cytokine signal
            transduction
  JOURNAL   Proc Natl Acad Sci U S A 97 (18), 10120-10125 (2000)
   PUBMED   10954736
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100661.1.
            
            On or before Dec 15, 2013 this sequence version replaced
            XM_003751750.2, XM_226098.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100661.1, SRR8487231.60875.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2762
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..2762
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /note="elongator acetyltransferase complex subunit 2"
                     /db_xref="GeneID:307545"
                     /db_xref="RGD:1306419"
     exon            1..164
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..2492
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /note="stIP1; SHINC-2; STAT3-interacting protein 1; signal
                     transducer and activator of transcription interacting
                     protein 1; elongation protein 2 homolog"
                     /codon_start=1
                     /product="elongator complex protein 2"
                     /protein_id="NP_001029317.1"
                     /db_xref="GeneID:307545"
                     /db_xref="RGD:1306419"
                     /translation="MVSSVLEVSYVFCCPNRARGALSWNSGPGGLLAFGTSCSVVLYD
                     PQKKVVITNLNGHTARVNCLHWIRTEDGSPSTELVSGASDNRVIHWELENNQVLKSVR
                     LQGHEGPVYAVHGIYQSGPSDGEQHALIASAASDSTVRLWSKKGSEVKCLQILKFGDG
                     FVLTVCLSTLPDTDAPVLACGDDGGRIHLFVQQDDWFQKMLSLCGHEDWIRGVEWATF
                     GRDLFLASCSQDCLIRIWRLYMKPTSLETEDGSIRLKENTFTIKDGGVSTTVAVILET
                     VLAGHENWVNAIHWQPSFYKDGVLHQPVRLLSASMDKTMILWAPDEESGVWLEQVRVG
                     EVGGNTLGFYGCQFGENGSMIIAHAFHGAMHLWKQSTVNPRQWAPEIVISGHFDGVQD
                     LIWDPEGEFIITTSTDQTTRLFAPWKKKNQSQVTWHEIARPQIHGYNLKCLAMIDRFQ
                     FVSGADEKVLRVFSAPRNFVENFSVISRQSLSHMLYDEDNDLPEGATVPALGLSNKAV
                     FEGDMTYLTSEEEELLSPAFGYPQVIFQPAVLSEPPTEDHLLQNTLWPEVQKLYGHGY
                     EIFCVTCNNSKTLLASACKAAQKEHAAIILWSTTSWKQVQSLAYHTLTVTQMAFSPDD
                     KFLLAVSRDRTWSLWKRQDVTSAEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDSKYF
                     FTGSRDKKVVVWGECNSSYNPMEHPINPCSSILDVGSCVTAVSVCPVLNPAQRYIVAV
                     GLESGKICIYSWSKTNQETKDWTSCVETTPSQSHTLGIRRLCWKSCSGSTEQSEEGTE
                     WLDFASCGEDHTVKIYRVNRCAL"
     exon            165..243
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            244..314
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            315..471
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            472..549
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            550..614
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            615..681
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            682..819
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            820..915
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1016
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1148
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1298
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1487
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1557
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1650
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1708
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1781
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1782..1974
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2096
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2097..2230
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2231..2338
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2339..2733
                     /gene="Elp2"
                     /gene_synonym="Statip1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctgggcca gtgaccatct ggcatcatgg tttcttctgt gttggaggtg tcttatgtgt
       61 tttgctgccc gaaccgggct cgaggagctt tgagttggaa ttccgggccc ggagggctcc
      121 tggccttcgg cacatcctgc tccgttgttc tctatgaccc tcagaaaaag gtagttatta
      181 ccaatctgaa tggtcatacc gctcgagtca actgcctaca ctggatacgt acagaggatg
      241 gctccccgtc cacagagctg gtgtctggag cttctgacaa tcgggtgatt cactgggaac
      301 tggagaacaa tcaggtttta aaatcagtcc gtctccaagg ccatgaagga ccggtttatg
      361 ctgtgcatgg tatttaccag agcgggccat ccgatggcga gcagcatgcc ctgatagctt
      421 ctgcagcttc cgattccaca gttcgactct ggtctaaaaa ggggtctgaa gtgaaatgcc
      481 ttcagatctt gaaattcggg gatggattcg ttctgactgt ctgcctgtcc actttgcctg
      541 atactgatgc gccagtgtta gcatgtggtg atgatggcgg cagaattcac ctgtttgttc
      601 agcaggatga ctggtttcag aaaatgcttt ctctgtgcgg acacgaggac tggataagag
      661 gcgtggaatg ggcaaccttc ggtagagacc ttttcctggc aagctgttca caggattgcc
      721 tcataagaat atggagactg tatatgaaac cgacatcttt agaaactgag gacggtagca
      781 taagactgaa ggaaaataca ttcactataa aagatggcgg tgttagcacg acggttgcag
      841 ttatcctgga gacagtgctg gctggacatg aaaactgggt gaatgccatt cactggcagc
      901 cttcgtttta caaagatggc gttctgcacc agccagtgag attgctgtct gcctccatgg
      961 acaaaaccat gattctttgg gctccagatg aagagtcagg ggtttggtta gagcaggtcc
     1021 gagtaggtga agtaggtgga aataccctgg ggttctatgg ttgccagttc ggtgaaaatg
     1081 gctccatgat catcgctcat gccttccacg gagcaatgca cctttggaaa caaagcacag
     1141 taaatccacg gcagtgggct ccagagatcg tcatttcagg acacttcgat ggtgtccaag
     1201 acctaatttg ggatccagag ggagagttca tcatcaccac cagcaccgat cagacaactc
     1261 gcctttttgc cccgtggaag aagaagaacc aatctcaggt gacgtggcat gagatcgcaa
     1321 ggcctcagat acatgggtac aacctcaagt gtttggcgat gattgatcgg tttcagttcg
     1381 tgtctggagc agatgaaaaa gttctccgtg ttttttctgc tcctcggaat tttgtggaaa
     1441 attttagtgt catttctcga cagtcgctga gtcacatgct ctatgatgaa gacaatgatc
     1501 ttccagaagg agccactgtt cctgcattag gactatcaaa taaagctgtc tttgagggag
     1561 acatgaccta cctgacttct gaagaggagg agctcttaag ccctgccttc gggtatcccc
     1621 aggtgatctt tcagcctgcc gtcctcagtg aaccccccac tgaggaccac cttctgcaga
     1681 acaccctgtg gcctgaggtt cagaaactgt atggacatgg ctatgagata ttttgtgtta
     1741 cttgtaacaa ttcaaagact ctacttgcct ctgcatgcaa ggcggctcag aaggaacacg
     1801 cagctatcat tctttggagc acgacatctt ggaaacaagt gcagagtctt gcttaccaca
     1861 ctctgaccgt cacacagatg gccttctcgc ctgatgacaa gttcttactg gctgtttcca
     1921 gagatcgaac ctggtctttg tggaagagac aggatgtgac ctcagcggag tttgatccgt
     1981 tttttagtct ttttgcattc accaacaaaa tcacttctgt gcatagtaga atcatttggt
     2041 cttgtgactg gagtcctgat agcaagtact tcttcactgg aagtcgagac aagaaggtgg
     2101 tggtctgggg cgagtgtaac tccagctata accccatgga gcaccccatt aatccctgct
     2161 cctcgatcct ggatgtgggc agttgtgtga cagctgtcag tgtctgccct gtgcttaacc
     2221 cagcccaaag atacattgtg gcagttggat tggagagtgg gaagatttgt atatactcct
     2281 ggagcaagac caatcaagaa accaaagact ggactagctg tgtagaaaca actccaagcc
     2341 aaagtcacac gctgggtatc agaaggttat gctggaagag ctgcagcggc agcactgagc
     2401 agagtgaaga ggggaccgag tggttggatt ttgcaagctg tggcgaggac catactgtga
     2461 agatttatag ggttaacaga tgtgcactgt gaaaacttga cctcaccctg cctgtcttga
     2521 ttgtcttaaa cgtttgttat gtaaatagat caccctttcc ttaccttagt gattgaatga
     2581 gtttccctgt ctactatctg atataggtca cgggctcttt cccttgtttt atcgcatgta
     2641 tgtaacctcc cagaacctta cccatgctgt cagagacgct tgggtctacc tctgtgtgtt
     2701 tcagattaag aacactttta atttgtgccc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2761 aa
//
