LOCUS       NM_001191844            1128 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ELOVL fatty acid elongase 7 (Elovl7), mRNA.
ACCESSION   NM_001191844 XM_342192
VERSION     NM_001191844.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Ohno,Y., Suto,S., Yamanaka,M., Mizutani,Y., Mitsutake,S.,
            Igarashi,Y., Sassa,T. and Kihara,A.
  TITLE     ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid
            synthesis
  JOURNAL   Proc Natl Acad Sci U S A 107 (43), 18439-18444 (2010)
   PUBMED   20937905
REFERENCE   2  (bases 1 to 1128)
  AUTHORS   Tamura,K., Makino,A., Hullin-Matsuda,F., Kobayashi,T., Furihata,M.,
            Chung,S., Ashida,S., Miki,T., Fujioka,T., Shuin,T., Nakamura,Y. and
            Nakagawa,H.
  TITLE     Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth
            through saturated long-chain fatty acid metabolism
  JOURNAL   Cancer Res 69 (20), 8133-8140 (2009)
   PUBMED   19826053
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jul 17, 2010 this sequence version replaced XM_342192.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO568810.1, SRR26643297.6682.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                JAXUCZ010000002.1  41562862-41562925
            65-255              JAXUCZ010000002.1  41572582-41572772
            256-336             JAXUCZ010000002.1  41576861-41576941
            337-393             JAXUCZ010000002.1  41578237-41578293
            394-499             JAXUCZ010000002.1  41580684-41580789
            500-636             JAXUCZ010000002.1  41585936-41586072
            637-1128            JAXUCZ010000002.1  41589800-41590291
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..1128
                     /gene="Elovl7"
                     /note="ELOVL fatty acid elongase 7"
                     /db_xref="GeneID:361895"
                     /db_xref="RGD:1310560"
     CDS             1..846
                     /gene="Elovl7"
                     /EC_number="2.3.1.199"
                     /note="elongation of very long chain fatty acids protein
                     7; ELOVL FA elongase 7; 3-keto acyl-CoA synthase Elovl7;
                     very long chain 3-oxoacyl-CoA synthase 7; very long chain
                     3-ketoacyl-CoA synthase 7"
                     /codon_start=1
                     /product="very long chain fatty acid elongase 7"
                     /protein_id="NP_001178773.1"
                     /db_xref="GeneID:361895"
                     /db_xref="RGD:1310560"
                     /translation="MAFSDLTSRTVRFYDNWIKDADPRVENWLLMSSPLPQTIILGLY
                     VYFVTSLGPKLMENRKPFELKKAMITYNFFIVLFSVYMCYEFVMSGWGTGYSFRCDIV
                     DYSQSPRAMRMVHTCWLYYFSKFIELFDTIFFVLRKKNSQVTFLHVFHHTIMPWTWWF
                     GVKFAAGGLGTFHALLNTAVHVVMYFYYGLCAMGPAYQKYLWWKKHLTSLQLVQFVLV
                     TVHIGQIFFMEDCNYQYPVFLYIIMSYGCIFLLLFLHFWYRAYTKGQRLPKTMENGNC
                     KSKHH"
     exon            1..64
                     /gene="Elovl7"
                     /inference="alignment:Splign:2.1.0"
     exon            65..255
                     /gene="Elovl7"
                     /inference="alignment:Splign:2.1.0"
     exon            256..336
                     /gene="Elovl7"
                     /inference="alignment:Splign:2.1.0"
     exon            337..393
                     /gene="Elovl7"
                     /inference="alignment:Splign:2.1.0"
     exon            394..499
                     /gene="Elovl7"
                     /inference="alignment:Splign:2.1.0"
     exon            500..636
                     /gene="Elovl7"
                     /inference="alignment:Splign:2.1.0"
     exon            637..1128
                     /gene="Elovl7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcgttca gcgatcttac atcgaggact gtgcgttttt atgataattg gatcaaagat
       61 gctgatccaa gagttgaaaa ctggctcctc atgtcctcgc ctctgccaca aaccatcatc
      121 ctggggctct acgtctattt tgttacatct ctgggaccaa agctcatgga gaaccggaag
      181 ccctttgaac tcaagaaagc gatgataacg tacaattttt tcatagtact gttttctgtg
      241 tatatgtgct atgagtttgt gatgtctggc tggggtacag gttattcgtt tcgatgcgac
      301 attgtggact attctcagtc gccaagagca atgaggatgg tacacacctg ctggctttat
      361 tacttctcca aatttatcga gctgtttgac actatctttt ttgttctgcg caagaaaaat
      421 agccaagtga ctttccttca tgtcttccat cacacgatca tgccatggac ctggtggttt
      481 ggagtcaaat ttgctgcagg tggtttgggg acattccacg cccttttaaa tacagctgtg
      541 cacgtggtca tgtatttcta ctatggactg tgtgcaatgg gaccagccta ccagaagtat
      601 ttatggtgga aaaagcatct gacctctttg cagcttgtcc agtttgttct tgtcactgtc
      661 cacataggac agatcttctt catggaagac tgcaattacc agtacccagt tttcctgtat
      721 atcatcatga gctatggatg catcttcctg ctactctttc tccacttttg gtaccgtgct
      781 tacaccaagg gtcaaaggtt gcccaaaact atggaaaacg ggaattgcaa aagcaagcac
      841 cactaaatcg caaacacagc ctggatttac aatggagact gctatcttgc cttccttgac
      901 aatcaagaca tacttgccta tgcagtgcat tttgtatatt tttcaaaacc aagagcttgt
      961 atttttatca taagctattt gggtttctga tctctgagag tccaaagctc ccagataagt
     1021 cttctcactg gaagagcctg gaacagccag gaggttccct gttgcctttc aaaccaatca
     1081 gaggtcttaa ttcatcttgc taacagggac aggaggatat gaagtgat
//
