LOCUS       NM_001134955            4578 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus engulfment and cell motility 2 (Elmo2), mRNA.
ACCESSION   NM_001134955 XM_342579
VERSION     NM_001134955.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4578)
  AUTHORS   Hiramoto-Yamaki N, Takeuchi S, Ueda S, Harada K, Fujimoto S,
            Negishi M and Katoh H.
  TITLE     Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent
            mechanism
  JOURNAL   J Cell Biol 190 (3), 461-477 (2010)
   PUBMED   20679435
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000120.1.
            
            [WARNING] On Mar 31, 2024 this sequence was replaced by
            NM_001134955.3.
            
            On Feb 10, 2021 this sequence version replaced NM_001134955.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                JACYVU010000120.1  8633341-8633392     c
            53-164              JACYVU010000120.1  8623722-8623833     c
            165-205             JACYVU010000120.1  8623475-8623515     c
            206-278             JACYVU010000120.1  8622991-8623063     c
            279-329             JACYVU010000120.1  8622300-8622350     c
            330-511             JACYVU010000120.1  8619507-8619688     c
            512-611             JACYVU010000120.1  8617960-8618059     c
            612-763             JACYVU010000120.1  8616675-8616826     c
            764-842             JACYVU010000120.1  8612642-8612720     c
            843-878             JACYVU010000120.1  8611568-8611603     c
            879-929             JACYVU010000120.1  8609796-8609846     c
            930-1052            JACYVU010000120.1  8606431-8606553     c
            1053-1187           JACYVU010000120.1  8606038-8606172     c
            1188-1292           JACYVU010000120.1  8605318-8605422     c
            1293-1401           JACYVU010000120.1  8605129-8605237     c
            1402-1538           JACYVU010000120.1  8604631-8604767     c
            1539-1702           JACYVU010000120.1  8603241-8603404     c
            1703-1815           JACYVU010000120.1  8603010-8603122     c
            1816-1923           JACYVU010000120.1  8602782-8602889     c
            1924-2006           JACYVU010000120.1  8601978-8602060     c
            2007-2084           JACYVU010000120.1  8600314-8600391     c
            2085-4578           JACYVU010000120.1  8595896-8598389     c
FEATURES             Location/Qualifiers
     source          1..4578
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..4578
                     /gene="Elmo2"
                     /note="engulfment and cell motility 2"
                     /db_xref="GeneID:362271"
                     /db_xref="RGD:1305784"
     exon            1..52
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            53..164
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..2285
                     /gene="Elmo2"
                     /note="engulfment and cell motility 2, ced-12 homolog;
                     engulfment and cell motility protein 2-like"
                     /codon_start=1
                     /product="engulfment and cell motility protein 2"
                     /protein_id="NP_001128427.1"
                     /db_xref="GeneID:362271"
                     /db_xref="RGD:1305784"
                     /translation="MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASVIKEVCDGWSLP
                     NPEYYTLRYADGPQLYVTEQTRSDIKNGTILQLAISPSRAARQLMERTQSSSMETRLD
                     AMKELAKLSADVTFATEFINMDGIVVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDH
                     GIVSWDLVSITFIKQIAGYVSQPMADVSVLQRSLAILESMVLNSQSLYQKIAEEITVG
                     QLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDKHLNPLDLPATDMANAFAQKHLR
                     SIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRI
                     AFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPALDFTQTPPGMLALDNMLYL
                     AKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMF
                     FTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFK
                     SKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSS
                     FRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTG
                     KDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDM
                     SSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG"
     exon            165..205
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            206..278
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            279..329
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            330..511
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            512..611
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            612..763
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            764..842
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            843..878
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            879..929
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1052
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1187
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1292
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1401
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1538
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1702
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1815
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1923
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2006
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            2007..2084
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..4578
                     /gene="Elmo2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccagagcgg cggcgggacg cgggcgagga gctgggcctc ggcaggcgcc gggcagctga
       61 gtcctgaagt agggccactg ggaacaatgc cacctccgtc ggacattgtc aaggtggcca
      121 ttgaatggcc aggtgctaat gcccagctcc ttgaaattga ccagaaacgg cccctggcat
      181 ctgtcatcaa ggaagtgtgc gatgggtggt cactgccaaa cccggagtac tacacgctcc
      241 gctatgcaga tgggccccag ctctatgtca ccgagcagac ccgaagcgac attaaaaatg
      301 ggacaatctt acaactggcc atctccccgt cccgggctgc acgccagctg atggaaagga
      361 cccagtcatc tagtatggag acccggctgg atgccatgaa ggagctggct aagctctcag
      421 ctgacgtgac tttcgccacc gagttcatca acatggatgg catcgttgtg ctgacaaggc
      481 tcgtggagag tgggaccaag ctcctgtccc actacagtga gatgctggca ttcaccctga
      541 ctgccttctt agagctcatg gaccatggca ttgtctcctg ggacttggtt tcaatcacct
      601 ttattaagca gattgcaggg tacgtgagcc agcccatggc cgatgtgtct gtcctccagc
      661 ggtccctggc catcctagag agcatggtac tgaacagcca gagcctatac cagaagatag
      721 cggaggagat caccgtggga cagctcatct cccacctgca ggtctccaac caggagatcc
      781 agacctacgc cattgctctg attaacgcgc tgttcctgaa ggccccggaa gacaagagac
      841 aggacaagca ccttaaccct ctagacctgc ccgccactga catggccaac gcctttgcac
      901 agaagcacct ccggtccata atcctgaacc atgtgatcag agggaatcga ccaatcaaaa
      961 cagagatggc ccatcagctc tatgtccttc aagtcttgac ctttaacctt ttggaagaaa
     1021 gaatgatgac caagatggat cccaatgacc aggctcaaag agacatcata tttgagctga
     1081 ggaggattgc attcgacgca gagtctgacc ccagcaatgc ccctgggagt gggaccgaga
     1141 agcgcaaggc catgtatacc aaggactata aaatgctagg gttcactaac catatcaacc
     1201 cagccttgga cttcacccag actcctcctg gaatgctggc tctggacaac atgctgtacc
     1261 tggccaaagt ccaccaggac acctacatcc ggatcgtgct ggagaacagt agccgggagg
     1321 acaaacacga gtgtccattc ggacgcagtg ctattgaact caccaagatg ctctgcgaga
     1381 tcctgcaggt cggggagctc ccaaacgaag gacgcaatga ctaccacccg atgttcttca
     1441 cccacgaccg agcgttcgag gagctctttg ggatctgcat ccagctgctg aacaagacct
     1501 ggaaagagat gagggcgacg gctgaggact tcaacaaggt tatgcaagtt gtccgagagc
     1561 agatcacccg ggctctgccc tctaaaccca actctttgga tcagttcaag agtaagcttc
     1621 gtagcctgag ctactcagaa atcctgcggc tgcgccagtc tgagaggatg agtcaggacg
     1681 acttccagtc cccgccaatc gtggagctcc gagagaagat ccagcctgag atcctggaac
     1741 tgatcaagca gcagcgcctg aatcggctat gtgagggcag cagcttccgg aagatcggga
     1801 accgtcgccg gcaagaaagg ttctggcact gccgcttggc gctgaaccac aaggttttgc
     1861 attatggtga cttggatgac aaccctcaag gggaggtgac attcgaatcc ctgcaggaga
     1921 aaatccctgt tgcagatatt aaggccattg tcactgggaa agactgtcct cacatgaaag
     1981 agaagagtgc cctgaaacag aacaaggagg tgttggaatt ggccttctcc atcctgtatg
     2041 atcctgatga gacactgaat ttcatcgctc ctaataagta tgagtactgc atctggatcg
     2101 atggcctcag cgcccttctg gggaaggata tgtccagcga gctaaccaag agcgacttgg
     2161 acacactgct gagcatggag atgaagctgc ggcttctgga cttggagaac attcagatcc
     2221 ctgaggcacc acctccagtc cccaaggagc ccagcagcta cgacttcgtc tatcactatg
     2281 gctgagcggg aagggactag ggcccaggag agacactggc agcccgtgcc ttgccctcca
     2341 tttgtacaaa ctactcctca aactcagtgg gacctggagc ttctctgtcc caaccattag
     2401 gagtcatgaa gtcagggcat gctgccctcc tcagcaccac agagcctggg tcgggttgga
     2461 ggagtgaact caagatgttc ttgcctccca cgctgagtct gcatctgcat ctggtactgg
     2521 acctaccgac agccatcccc tttcctttca agcctcctct ctggttggct ggagaaccca
     2581 catgggctgg agctggtcca tgaaaggctg cccgtggggg cgagaggctt ggggatgggg
     2641 agagccttgg agtgactgtc ttcaggtgac tcaggcaaga acagccttga gctcttgctt
     2701 cataggtctt tgagggctca ttccagcctt atcctgtgcc aagatgctgc tgcctctggg
     2761 tttaccacct ctactctcta gagatacccg tctctcttgt ccatgcaggt atcaggacag
     2821 gtagtaactt tcccccaagc actcagtctc atcctgccca ggcagaggcc tccagcttga
     2881 gtcttgctct ctcgggctct aggaatgctg caaggaaagg cgaggtgaga cctctagctc
     2941 accccttcag ttctgtcttg tccttgctgt ggaagaatgc tcccatcccc cttagttaca
     3001 ggcccttcta tttgtgcccc tcttgccgca gacgaggggc gttgccttcc ctctctcctt
     3061 cctggcactg tggtttctgc cgttagccat gatttcaaga agtaccgggg ccacagctgt
     3121 gccatgggcc ttcattggtg ctgcagcact tgaagcacgc gcacagcctc cttccttgga
     3181 cgcatgttaa atggtggtat tcagcattgg cagcctagcg tggcgggtac tgcccaatga
     3241 agagtgtact atatattttc tttactatag gccatactta tgcagacatg tatatatatt
     3301 tatataagat cttcctatcc taggatagga tgtttaagag gaataaagtt gagagcaaag
     3361 ctgctgtgct ctcagtcgtg agttgagtgt aaccagagag cagccagggg cttcctgtca
     3421 gtcacagtgt tttcaataaa tactctttca tgtagactgg ttcctgtcaa cacctcttcc
     3481 tctacacttg ttccctgccc caagggtagg gagccacctg gcggtcttca cttcagtgtg
     3541 cctgggagcg tctggagagc tccagccacc ttccaagagc atctccctct cccctggttg
     3601 atcctgctct gtcacgcaca gactactcac acctgctggc tgaggatgct cacagactgt
     3661 ggtacaggac agagcgtttc ctgctcagcc ctgctgggta caacgtggaa aggcatactg
     3721 tacaccccca agaacccatc ctcccttttt tccctgccag ggacacagcc agggaacaga
     3781 tcaagtactt gtgcctttca aagaagacat gttctgcacc ccgtgtgttg cctgcgctca
     3841 gtacccagcc ttccagctgg tgctttaagc tgttgctcct accagcagcc tcggtagcgg
     3901 ggaggtttga atgagagcag tgatgaaaat agatacttcc tcttgccgct gtcagaaggg
     3961 gggggggggg tgaggacagg cgctttcaga aggcatagaa agtgcatgca acacaggcct
     4021 tgagcactga atgaagccag gaccttgggc tgcaatgggc accactgtag gtcttaggaa
     4081 gcattgaata aactaaagct ttcgtggtgc cagctggcag cagcctgcag cagcagtgcg
     4141 cacaaagcac agcttacact ctggccttga gccttctgct aggagccagg agcccagcca
     4201 agtcatgtgc aagaatctct gtttgcagcc agtcctagta gagcccggat gagcagaagc
     4261 ccagaagtgg gccagctcgg gtttgcagcc ctagcttgct tggcttaaga gattatcttg
     4321 ctcacgtacc ctgttcctaa aatgaatcaa atccaggtat gctaaattgt tctgaggcca
     4381 cctgtcttcc tgggctccca gtaagactag atccttctca tccacttcct ttcgggttcc
     4441 atttcctctg ggatgaactt cccgtactca gcttattgaa taattctcac aaaagtatag
     4501 gcacatgtaa tttcacaaag tgtccattat tactttgcca agatctttta cctctaaaat
     4561 ttaatggttg tcaaatca
//
