LOCUS       NM_001011957            1660 bp    mRNA    linear   ROD 06-MAY-2024
DEFINITION  Rattus norvegicus elongation factor for RNA polymerase II 3 (Ell3),
            transcript variant 1, mRNA.
ACCESSION   NM_001011957 XM_230508 XM_347326
VERSION     NM_001011957.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Lin,C., Garruss,A.S., Luo,Z., Guo,F. and Shilatifard,A.
  TITLE     The RNA Pol II elongation factor Ell3 marks enhancers in ES cells
            and primes future gene activation
  JOURNAL   Cell 152 (1-2), 144-156 (2013)
   PUBMED   23273992
REFERENCE   2  (bases 1 to 1660)
  AUTHORS   Luo,Z., Lin,C. and Shilatifard,A.
  TITLE     The super elongation complex (SEC) family in transcriptional
            control
  JOURNAL   Nat Rev Mol Cell Biol 13 (9), 543-547 (2012)
   PUBMED   22895430
  REMARK    Review article
REFERENCE   3  (bases 1 to 1660)
  AUTHORS   Ahn,H.J., Cha,Y., Moon,S.H., Jung,J.E. and Park,K.S.
  TITLE     Ell3 enhances differentiation of mouse embryonic stem cells by
            regulating epithelial-mesenchymal transition and apoptosis
  JOURNAL   PLoS One 7 (6), e40293 (2012)
   PUBMED   22768269
REFERENCE   4  (bases 1 to 1660)
  AUTHORS   Smith,E.R., Lin,C., Garrett,A.S., Thornton,J., Mohaghegh,N., Hu,D.,
            Jackson,J., Saraf,A., Swanson,S.K., Seidel,C., Florens,L.,
            Washburn,M.P., Eissenberg,J.C. and Shilatifard,A.
  TITLE     The little elongation complex regulates small nuclear RNA
            transcription
  JOURNAL   Mol Cell 44 (6), 954-965 (2011)
   PUBMED   22195968
REFERENCE   5  (bases 1 to 1660)
  AUTHORS   Miller,T., Williams,K., Johnstone,R.W. and Shilatifard,A.
  TITLE     Identification, cloning, expression, and biochemical
            characterization of the testis-specific RNA polymerase II
            elongation factor ELL3
  JOURNAL   J Biol Chem 275 (41), 32052-32056 (2000)
   PUBMED   10882741
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC084693.1.
            
            On or before Feb 11, 2005 this sequence version replaced
            XM_230508.2, XM_347326.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC084693.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132269,
                                           SAMD00132279 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..1660
                     /gene="Ell3"
                     /note="elongation factor for RNA polymerase II 3"
                     /db_xref="GeneID:296102"
                     /db_xref="RGD:1309917"
     exon            1..184
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..1216
                     /gene="Ell3"
                     /note="isoform 1 is encoded by transcript variant 1; RNA
                     polymerase II elongation factor ELL3; elongation factor
                     RNA polymerase II-like 3"
                     /codon_start=1
                     /product="RNA polymerase II elongation factor ELL3 isoform
                     1"
                     /protein_id="NP_001011957.1"
                     /db_xref="GeneID:296102"
                     /db_xref="RGD:1309917"
                     /translation="MEGTQEALSGKMRLLFTPAARTSLLMLRLNEAALRALQECQQQQ
                     VRPVIAFQGQRGYLRLPGPGWSCLFSFIVSQCGQEGGGLDLVYQRLGRSGPNCLHCLG
                     SLRERLTIWAAMDTIPAPLLAQEHLTEGTRESESWQDSEDEPEGHPQMALQEVSDPLA
                     SNHEQSLPGSSSEPMAQWEVRNHTYLSNREPDQPLPSSASQKRLDKKRSAPITTEEPE
                     EKRPRALPLASSPLQGLSNQDSPEEQDWGQDADGDSRLEQSLSVQSASESPSPEEVPD
                     YLLQYSTIHSAEQQQAYEQDFETDYAEYRILHARVGAASQRFTELGAEIKRLQRGTPE
                     HKVLEDKIVQEYKKFRKRYPSYSEEKRRCEYLHEKLSHIKGLILEFEEKNRGS"
     exon            185..220
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            221..327
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            328..514
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            515..594
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            595..670
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            671..845
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            846..888
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            889..1060
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1105
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1628
                     /gene="Ell3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggtggccc tcgcctgtgg tcccagatct gcatgtgcgc gactttggca ccatggaggg
       61 gacccaggaa gctctgagtg ggaaaatgcg gctcctcttc acccctgctg ctcgaaccag
      121 cctcctgatg ctaagactca acgaggcggc gctgcgggca ctacaagagt gtcagcagca
      181 acaggtacgg ccagtgatcg ctttccaagg ccaacgaggg tatctaaggc tcccaggtcc
      241 tggatggtcc tgcctcttct ccttcatagt atcccagtgt ggccaagagg gtggtggctt
      301 ggaccttgtg taccaacgct taggcagatc tgggcctaac tgtctccact gcctgggctc
      361 actgagagag cgacttacta tttgggcagc catggatacg atcccagctc cactgttagc
      421 tcaggaacac ctgactgaag gtaccagaga gtctgagagc tggcaggaca gcgaagatga
      481 acctgaaggc catccccaga tggcactaca agaggtgtct gacccactgg caagcaacca
      541 tgaacagtca ctcccaggat cctccagtga gcccatggca cagtgggaag tgagaaacca
      601 cacttacctt tcaaacagag agcctgatca gccactgcct tcctctgcta gccagaaacg
      661 cctggacaag aaacgttcag cacctataac cactgaagaa ccagaggaaa aaaggcccag
      721 agctctgcct ctagcctcaa gtccactaca aggactatca aatcaggact caccagagga
      781 acaagactgg gggcaagatg cagatggaga ttccaggctg gagcagagtc tctcagttca
      841 atcagcttct gaatccccaa gccctgagga ggtaccagat tatctcctgc aatacagcac
      901 catccacagt gcagagcagc agcaggccta cgagcaggac tttgagaccg actatgctga
      961 ataccgcatt ctgcacgccc gtgtcggggc tgcaagccag aggttcacag agctgggggc
     1021 agagatcaag agacttcagc gaggaactcc agagcacaag gtgctagaag acaagatagt
     1081 ccaggagtat aaaaagttca gaaagcggta tcccagttac agcgaggaga agcggcgctg
     1141 tgagtacctg catgagaaac tgtcccacat taaaggtctc atcctggaat ttgaggaaaa
     1201 gaacaggggc agctgaaact gtccagaggg cttgaccctt ccttccccag tgattaacca
     1261 aacagctgaa agatggagcc catctgtgtt tcttatatcc gcggtggcag gagagccatg
     1321 ctaggttctt gcaggttgat ttttgatgtt gccgtaattt tttagggtgt gggcatggta
     1381 tcatctcctc agctgtgccc aggggactag gaaagtagga gacgcttggc ttcttcaact
     1441 ttattttagc taagtcattt tcagatcctg aaaagtgaca tttccaggtt aaccttgaga
     1501 atgttaggca agcaagcaag tttagtaaag ttgccttgca ggaatgagaa cttctggtgg
     1561 tggagctcat tggacttaca gtgtacctag atgtaacatg actgaaaaat taaaactgat
     1621 tgcttctgaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
