LOCUS       NM_001108743            3825 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ETS transcription factor ELK3 (Elk3), mRNA.
ACCESSION   NM_001108743 XM_001080272 XM_343198
VERSION     NM_001108743.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3825)
  AUTHORS   Kerr,N., Pintzas,A., Holmes,F., Hobson,S.A., Pope,R., Wallace,M.,
            Wasylyk,C., Wasylyk,B. and Wynick,D.
  TITLE     The expression of ELK transcription factors in adult DRG: Novel
            isoforms, antisense transcripts and upregulation by nerve damage
  JOURNAL   Mol Cell Neurosci 44 (2), 165-177 (2010)
   PUBMED   20304071
REFERENCE   2  (bases 1 to 3825)
  AUTHORS   Gupta,M., Sueblinvong,V., Raman,J., Jeevanandam,V. and Gupta,M.P.
  TITLE     Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a
            purine-rich negative regulatory element of the alpha-myosin heavy
            chain gene and control transcriptional and translational regulation
            of the gene expression. Implications in the repression of
            alpha-myosin heavy chain during heart failure
  JOURNAL   J Biol Chem 278 (45), 44935-44948 (2003)
   PUBMED   12933792
REFERENCE   3  (bases 1 to 3825)
  AUTHORS   Zheng,H., Wasylyk,C., Ayadi,A., Abecassis,J., Schalken,J.A.,
            Rogatsch,H., Wernert,N., Maira,S.M., Multon,M.C. and Wasylyk,B.
  TITLE     The transcription factor Net regulates the angiogenic switch
  JOURNAL   Genes Dev 17 (18), 2283-2297 (2003)
   PUBMED   12975317
REFERENCE   4  (bases 1 to 3825)
  AUTHORS   Yamazaki,Y., Kubota,H., Nozaki,M. and Nagata,K.
  TITLE     Transcriptional regulation of the cytosolic chaperonin theta
            subunit gene, Cctq, by Ets domain transcription factors Elk-1,
            Sap-1a, and Net in the absence of serum response factor
  JOURNAL   J Biol Chem 278 (33), 30642-30651 (2003)
   PUBMED   12788937
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473960.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001080272.1, XM_343198.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN11044071,
                              SAMN16676785 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3825
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..3825
                     /gene="Elk3"
                     /note="ETS transcription factor ELK3"
                     /db_xref="GeneID:362871"
                     /db_xref="RGD:1307764"
     exon            1..210
                     /gene="Elk3"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..1230
                     /gene="Elk3"
                     /note="ELK3, member of ETS oncogene family; ELK3,
                     ETS-domain protein; ELK3, ETS transcription factor"
                     /codon_start=1
                     /product="ETS domain-containing protein Elk-3"
                     /protein_id="NP_001102213.1"
                     /db_xref="GeneID:362871"
                     /db_xref="RGD:1307764"
                     /translation="MESAITLWQFLLHLLLDQKHEHLICWTSNDGEFKLLKAEEVAKL
                     WGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPDILKMDPHAVEISR
                     ESLLLQDSDCKVSPEGREIHKHGLSSLKSASRNEYIHSGLYSSFTINSLQNAPEAFKA
                     IKTEKLEEPCDDSPPVEEVRTVIRFVTNKTDKHITRPVVSLPSTSEAAAAASAFLASS
                     VSAKISSLMLPNAASVSSASPSSSRSPSLSPNSPLPSEHRSLFLEAACHDADSLEPLN
                     LSSGSKTKSPSLPPKGKKPKGLEISAPQLLLSGTDIGSIALNSPALPSGSLTPAFFSA
                     QTPSGLLLTPSPLLPSIHFWSSLSPVAPLSPARLQGPNTLFQFPTLLNGHMPMPLPSL
                     DRAPSPVLLSSSSQKS"
     exon            211..1008
                     /gene="Elk3"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1131
                     /gene="Elk3"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..3825
                     /gene="Elk3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtatggaga gtgcaatcac cctgtggcag ttccttttgc acttgctgct ggaccagaaa
       61 catgagcacc tcatctgctg gacgtctaac gatggcgagt tcaaactcct caaggctgaa
      121 gaagtggcca aactgtgggg cctccgcaag aacaagacaa acatgaacta cgacaagctg
      181 agcagggctc tgagatacta ttacgacaag aacattatca agaaagtgat cgggcagaag
      241 tttgtgtaca agttcgtctc tttcccggat atcctaaaaa tggatcctca cgcggtagag
      301 atcagccggg agagcctcct gctgcaggac agcgactgta aggtgtcccc ggaaggccga
      361 gagatccaca agcacggctt gtcttccctc aaaagcgcga gccgcaacga atacatccac
      421 tcaggcctgt actcgtcctt caccatcaac tccctgcaga acgctccaga ggccttcaag
      481 gccatcaaga cagagaagct ggaggagcca tgtgatgaca gcccccctgt ggaagaagtc
      541 aggactgtga tcaggtttgt gaccaataaa accgacaagc acatcaccag gcctgtggtg
      601 tccctgcctt ccacatccga ggccgccgcg gcggcatccg ctttcctggc ctcgtctgtt
      661 tcagccaaga tctcctcttt aatgttgcca aatgctgcca gcgtttcgtc tgcatcaccc
      721 tcttcatctc ggtccccatc cctgtccccc aactctcccc tcccttccga acatagaagc
      781 ctcttcctgg aggcagcctg ccatgacgcg gattctctgg agcccctaaa tctgtcatcg
      841 ggctccaaaa ccaagtctcc atctcttccc ccaaaaggca aaaaacccaa aggcttggaa
      901 atctccgcgc cccaactgtt gctctccggc accgacatcg gctccatcgc cctcaacagc
      961 ccagccctcc cctcaggatc cctcactcca gctttcttca gtgcacagac gccaagtgga
     1021 ctgcttctga ccccaagtcc gctgctcccc agcatacatt tctggagcag ccttagtccg
     1081 gtcgccccgc tgagtcccgc taggctgcaa gggccaaaca cacttttcca gttccccaca
     1141 ctgctcaatg gtcacatgcc catgccgctc cccagtctgg atagagcccc atctccagta
     1201 ctgctgtcct ccagctctca gaaatcatga tgacagccac cgccactgtc agcgactaag
     1261 gactcacaga actgatgatg ccagtttgtc cctctgggct agtttacctg tgtcatgaga
     1321 aggacgtcgt gaaacccggt caatttggtt tgcacttttc ataacacgga taatctagat
     1381 gtatgtcacc attttaaaag acggttttat atatatatat atatatatat atatatatat
     1441 atatatatat acatatatat atatatatat ttcagctctc tatggaagtc tgttttgcat
     1501 caagtggatt ttaatgtttg ttttttatcc tgttagctct ggagtgttga acactgacag
     1561 tgaggagcct ttcttaatgt tttcagtgta actaataagg ctgtgaagct ttctatcgct
     1621 ttaaatctac atatgctgag ctctgcttgt atacacggta taaccagctg tgccttcctt
     1681 tgcatttagt tttatgtaca tgaacttgtg tatttctagt attgagagga aatgtttgaa
     1741 ggacgcattg gcatcaaaca gctctcagta gagtgctatt ttctcacgta gacaccatca
     1801 aagtgtactt ctatcactaa gaactgcctt aggacttctt ttgaactgaa atccagtaaa
     1861 tacaatgtcc aagtaatgtt tttataagaa tgaacgaagc catatttaga caataaacat
     1921 tctttaaaga acatgttcca aagtgcattt tttaaaagga gaactttgag aggccagtgg
     1981 cttagtcatc tatagaggcc tttctaaccc cccggcagaa gtctgggctg ctaaggctat
     2041 gttaagtcca tgccagccaa actctcgagg ggacttccca ggtttgtgtt taatttaaag
     2101 actagccctg ccttcttcat ttcctacaac cacagccatc tgggatctta tcactgctgg
     2161 gagttaaggt ttcttaagat tcctggcacg gcaattaata tttaaaacct aatgttgtag
     2221 ggctgaggac ttagctcagt agaatgtgtg ccctgcatgt gctgaggcag tgggtacaaa
     2281 ccccaggaat ctgtctccct gcctctccca aagagggggc tgggagacaa actaagaatg
     2341 ttttggagag atgctcacag atggcgaatt caaacaaaga aacgattata taataccagc
     2401 tttctgtaga tatacttcct gtgtataggt aatttttggt ggattaaagc aaaatgcgtt
     2461 actaagatct ggaggaactg aaagccttgc ttctcaagat gagcgcccga gagacactgc
     2521 tttctgtatt caattggtgg cgagaaggaa ggcaatccga taaaggaaaa ctcttcagga
     2581 atctcactct gaatccgagg cagcagctcc tcggatgctc tgcagggaag gcttcatgtg
     2641 ccgtgggtca gggctgtgaa ggcggcaggc cctcatctgg taaaacccag aaggtagcag
     2701 cacatttgtg cttaagggga agtcctgatg taagactatg gactcaaagt gctttcaatt
     2761 taagatcagg tgagctgaaa cactacttat ccacaagtag ttaaaaaaaa ccaaaaacaa
     2821 aaaccaaagt acaatttgaa atgtgcctca acagaataga taaataacaa atcataaggg
     2881 ggctaaaaaa aagtttatgc aaaaaaaatc tgaattttaa acaattaaaa ttatgtttag
     2941 atacttacaa attgagactt agtaccggaa tgggactatc tttctaaggg gtgtgtgctt
     3001 actaagagaa gagaaaaagc ctctgactgt aaggccatga agacagctcc aagcccataa
     3061 atagacaccc tgccactccc tcatggcaaa gaataaatgt gtactaaaat aaaaaggatc
     3121 tggttcaggg gactataatt actgaacgca gtgtcagagc tgggaggggc tttcagaggg
     3181 cgtgcttccg ctgttctccg gtcaagacag gcccacagaa ccaggtgaga ggcagggagc
     3241 ggcctggggc cacagcattc actgagggta gagtgggagt ggttcaacac ctacggaaac
     3301 atcaggctgg agtgctgaaa attgcttgat gagggtgcgt ttgatatgca agattcttag
     3361 gaaggaacaa ggagtgtgca ggaatctcaa cagaatgact ttttgtagac ttttaaacta
     3421 taaatgctgg ctggaaatgt tcatgtgact gtaagtctgc ctgctgtttc cttgtcctcc
     3481 aattactgtg attatcctgt attctagata cactgtgtca ttcttggtga gtccaaatac
     3541 tcaagggaga actgaagatg gagaataaca gcttcgccgt cttctgtgtt tttaacagga
     3601 ttaatttagc cagaaaatag gctgcaaaaa gcatccccgg ctcttatgct tgcttaatca
     3661 gtgttcagct gctgcagctg ccgttggagc tctagaacct cactgtggaa gctgaactca
     3721 gtccctgcgc agcttcccta cagctgagaa gcttcctccg ctgccacatg ggtgtcgttt
     3781 ttttactgtc atattgtttt gttgaataaa tactttgtaa taaaa
//
