LOCUS       NM_001105913            4178 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus extracellular leucine-rich repeat and fibronectin
            type III domain containing 1 (Elfn1), mRNA.
ACCESSION   NM_001105913 XM_001074045 XM_221954
VERSION     NM_001105913.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4178)
  AUTHORS   Sylwestrak,E.L. and Ghosh,A.
  TITLE     Elfn1 regulates target-specific release probability at
            CA1-interneuron synapses
  JOURNAL   Science 338 (6106), 536-540 (2012)
   PUBMED   23042292
REFERENCE   2  (bases 1 to 4178)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001105913.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676786
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-357               JAXUCZ010000012.1  19838081-19838437   c
            358-4178            JAXUCZ010000012.1  19773914-19777734   c
FEATURES             Location/Qualifiers
     source          1..4178
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..4178
                     /gene="Elfn1"
                     /gene_synonym="Ppp1r28; RGD1308787"
                     /note="extracellular leucine-rich repeat and fibronectin
                     type III domain containing 1"
                     /db_xref="GeneID:288512"
                     /db_xref="RGD:1308787"
     exon            1..357
                     /gene="Elfn1"
                     /gene_synonym="Ppp1r28; RGD1308787"
                     /inference="alignment:Splign:2.1.0"
     exon            358..4178
                     /gene="Elfn1"
                     /gene_synonym="Ppp1r28; RGD1308787"
                     /inference="alignment:Splign:2.1.0"
     CDS             622..3111
                     /gene="Elfn1"
                     /gene_synonym="Ppp1r28; RGD1308787"
                     /note="leucine rich repeat and fibronectin type III,
                     extracellular 1; extracellular leucine-rich repeat and
                     fibronectin type-III domain-containing protein 1; protein
                     phosphatase 1, regulatory subunit 28"
                     /codon_start=1
                     /product="protein ELFN1 precursor"
                     /protein_id="NP_001099383.1"
                     /db_xref="GeneID:288512"
                     /db_xref="RGD:1308787"
                     /translation="MAGHGWGAPWVLVAAATLLHACGLAQGDCWLIEGDKGFVWLAIC
                     SQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDG
                     AFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVN
                     IDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRV
                     QCESPPVYAGYFLLGQGRHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHS
                     PPPPPPEPSDMPCADDECFSGDGTTPLVVLTTLVPQTEARPSMKVKQLTQNSATIMVQ
                     LPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNH
                     TCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKH
                     KKAVAAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQ
                     YKLVESGETPKATKGNYIEVRTGEPPERRGCELSRPAPETQSSVAEISTIAKEVDRVN
                     QIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGG
                     LQRHHSVEAATGPPRASTSSSGSARSPRTFRAETAGAHKAPATETKYIEKSSPVPETI
                     LTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPPPPPPTHEGLGGRKASILEP
                     LTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAG
                     HALRKKVQFAKDEDLHDILDYWKGVSAQHKS"
ORIGIN      
        1 cggccgcccc gcctgcccga ccggtccggg gctgctccga tcgcgcggtc cccggctctt
       61 gacgcagtga gcgccgcagc ccggctcccg caggctcctc tccgctccgg gcgagaggcc
      121 gatccccaag cccggcgggc tccgggaggg gcgggcaaca cgggaagggg aggaggtctg
      181 tctggagcca gcgagaaccc caaggaggaa gaggaggagg aagccggggc agccgccacc
      241 gccgccgccg ccgccgccgc cgccgccgcc tccacagtcg ccggggcgct tcggggactt
      301 gggcgcgcgc tagcgggcga ccgagctttc agccctgggg gccacaagcc ggttcagcag
      361 agaacacttc aggcagagga accgggcgaa gccaccagga cacacaggcc catggaaaag
      421 caagctgtgg tcacctcagg acccgggagg acgacaaggg gcggtgggca gtgagggagc
      481 cattctccct cccagcacct gcgccatgca gcttgggaca ggacatctct gacagtgcag
      541 gcagtgctat atcccatccc taagtcccct ggggagggac cactgcccat cccccgcatc
      601 cccaaggcag agtgtcccaa gatggctggg cacgggtggg gtgcaccgtg ggtacttgtg
      661 gcagccgcca cattactgca cgcttgtggg ctggcccaag gtgactgctg gctgattgag
      721 ggtgacaagg gcttcgtgtg gctggccatc tgcagtcaga accagccgcc ctatgaggcc
      781 atcccccagc agatcaacaa caccatcgtg gacctgcggc ttaacgagaa ccgcatccgc
      841 agcgtgcagt acgcgtccct cagccgcttc gggaacctca catacctcaa cctcaccaag
      901 aatgagatag gctacatcga ggacggggcc ttctctggcc agttcaacct ccaggtgctg
      961 cagctgggtt acaaccggct gcgcaacctt acggagggca tgctgagggg cctgagcaag
     1021 ctcgagtacc tgtatctgca ggccaacctc atcgaggtgg tgatggccag cgccttctgg
     1081 gagtgcccca acatagtcaa catagatctc tccatgaacc gcatccagca gcttggcagt
     1141 ggcaccttcg cgggcctgac caagctctcg gtgtgcgaga tttacagcaa ccctttctac
     1201 tgctcctgcg agctgctggg tttcctgcgc tggctggcag ccttcaccaa cgccacccag
     1261 acccacgacc gtgtgcagtg tgagtctcct cccgtctacg cgggctactt cctcctgggc
     1321 caaggccgcc acggccacca acgtagcatc cttagcaagc tgcagtccgt gtgcactgag
     1381 ggctcctaca ctgctgaagt gcttggcccg ccccgcccgg tgcccggccg atcacagcca
     1441 ggacattcgc cacctccgcc tcctccagag cccagtgaca tgccctgcgc tgatgacgag
     1501 tgcttctctg gagacggcac cacgccactg gtggtcctga cgacactggt ccctcagaca
     1561 gaggcccgtc cctccatgaa agtcaagcag ctgacccaga actcagccac catcatggtg
     1621 cagctgccca gccctttcaa ccgcatgtac acactggagc agtacaacaa cagtaaatcg
     1681 ttcacggtgt ccaagctgac tcagcctcag gaggagatcc gcctcaccaa tctctacacg
     1741 ctcaccaact acacgtactg cgtggtctcc acgagttctg gcacccatca taaccacacc
     1801 tgccttacca tctgcctgcc caagccaccc agcccacccg gccccgtgcc cagcccctcc
     1861 acagccaccc actacatcat gaccatcctg ggctgcctct tcggcatggt gctggtgctg
     1921 ggtgccgtgt actactgcct gcgaaagcgg aggcgacagg aggagaaaca caagaaggcc
     1981 gtggcagcag ccgctggcag cttgaaaaag accatcattg aacttaagta cggccctgag
     2041 atcgaggcac ccgggctggc tccgctgacc cagggcccgc tgctgggccc tgaggctgtg
     2101 actcgaatac cctacctgcc agctgccacc agcgacgtgg agcagtataa gctggtggag
     2161 agcggcgaga cccccaaggc caccaagggg aactacattg aagtgcgcac aggggagccg
     2221 ccggaacgca gaggctgtga gctgagccgg cctgcccctg aaacccagag ctcggtagcc
     2281 gagatctcca ccattgccaa ggaagtggac agagtcaacc agatcattaa caactgcata
     2341 gacgcactca agtcagaatc cacctccttc cagggcgcca aatcaggggc cgtgtccgcg
     2401 gctgagccgc agctggtgct gctgtccgag cctctggcca gcaagcacag cttcctatcc
     2461 cctgtataca aagatgcctt tggccatggt ggcctgcagc ggcaccacag tgtggaggct
     2521 gcgaccgggc ccccgagggc cagcacttca tccagcggtt ctgcacgcag ccctcgcacc
     2581 ttccgggctg agacggccgg cgcacataag gccccagcca ccgagaccaa gtacattgaa
     2641 aaaagctcac ctgtgcccga gaccatcctc actgtgacac ccgcggccac tgtgctgcgg
     2701 gcggaggccg acaagagtcg ccagtatggc gagcatcggc actcgtaccc cggctctcac
     2761 cctgccgagc cacctgctcc gccaccacct ccacccactc atgagggttt gggaggccga
     2821 aaggcatcta tcttggagcc tctgacccgg ccacgacccc gagacctcgt ctactcgcaa
     2881 ctgtccccgc agtaccacaa cctgagctat tcatccagcc ccgagtacac ctgcagggca
     2941 tccccaagca tctgggagcg tctcagacta agccggcgga gacacaagga tgatgcggag
     3001 ttcatggcgg ctggccacgc cctgcgcaag aaggtccagt ttgctaaaga cgaggacctg
     3061 catgacatcc tagactactg gaaaggcgtg tctgcccagc acaagtcctg aacctcccca
     3121 cccccacctc ccaccccccc acccccccac cccccacccc gttagcaggg ccaaaggcag
     3181 cctggccctg tcctctccga aactcgtgat gccctttgga ccaaaaagga cagaccatcc
     3241 acagcagcta tccctgactg agactcaaca ctaaatccaa cgtatgtgca caatcagggg
     3301 ccgctgcgtt ccgcacctgg cccacaggga cagcttgagg aggccgcagg tggccgcaac
     3361 agtagatata ctaatttcca tgtaaactgt aatgtgcctg ctgcctggtg caagcaagca
     3421 agcaagacac acacacacac acacacacac acacacactc acacacacac acacacactc
     3481 acacacaaat gcatacacat gcatgtgcgc gtgcacacac aaacatacgc acatgcatgc
     3541 acacactctc acacacacac atgcacagac atgcacacat gggacttcgg aaaactgtgt
     3601 cttaggggtg ggggtggggg aggggaagtt tttccattat ctttcctgtt ttgagtcttc
     3661 tctttctttt cctcctttct tctctctctc tctctctctc tctctctctc tctctctctc
     3721 tttattttct tcctttttaa aaatatatat ataaaaatga aaatcttaaa aaaaaaagaa
     3781 agaaaaaaag aaaggagaaa gaactaaatc acctagcgtg gggtgcgtga ccagtatagc
     3841 cagcttcaag gcacccccta aatatgatct ccaggctgtg gagtgcaaag gggtggagcc
     3901 aaggcagatg ggccactggc ccttggcagc atccagaggc tgtgggactc tagtggggag
     3961 gtggagactg tgcctgggga ccggtcaggg tggcaagagg ggtgcaggct gggaaacatt
     4021 gtgggtcccc cccacctcgg ccccatcttc attgtatact gtagttgttc tattgtacag
     4081 aaaaaaaatc tatatttgca aagtttgctg taaaatgaga gagaaaaaaa gactatgtct
     4141 acttaaaaaa aaaaaaactc agcaaagaaa aaaaatcc
//
