LOCUS       NM_001191735            2448 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus E74 like ETS transcription factor 4 (Elf4), mRNA.
ACCESSION   NM_001191735 XM_229125
VERSION     NM_001191735.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2448)
  AUTHORS   Ayuso,M.I., Martinez-Alonso,E., Regidor,I. and Alcazar,A.
  TITLE     Stress Granule Induction after Brain Ischemia Is Independent of
            Eukaryotic Translation Initiation Factor (eIF) 2alpha
            Phosphorylation and Is Correlated with a Decrease in eIF4B and
            eIF4E Proteins
  JOURNAL   J Biol Chem 291 (53), 27252-27264 (2016)
   PUBMED   27836976
  REMARK    GeneRIF: Low eIF4E and eIF4B expression is associated with Brain
            Ischemia.
REFERENCE   2  (bases 1 to 2448)
  AUTHORS   Gronli,J., Dagestad,G., Milde,A.M., Murison,R. and Bramham,C.R.
  TITLE     Post-transcriptional effects and interactions between chronic mild
            stress and acute sleep deprivation: regulation of translation
            factor and cytoplasmic polyadenylation element-binding protein
            phosphorylation
  JOURNAL   Behav Brain Res 235 (2), 251-262 (2012)
   PUBMED   22917528
  REMARK    GeneRIF: The eEF2 phosphorylation was decreased in all brain
            regions after sleep deprivation and enhanced
REFERENCE   3  (bases 1 to 2448)
  AUTHORS   Cho,J.Y., Akbarali,Y., Zerbini,L.F., Gu,X., Boltax,J., Wang,Y.,
            Oettgen,P., Zhang,D.E. and Libermann,T.A.
  TITLE     Isoforms of the Ets transcription factor NERF/ELF-2 physically
            interact with AML1 and mediate opposing effects on AML1-mediated
            transcription of the B cell-specific blk gene
  JOURNAL   J Biol Chem 279 (19), 19512-19522 (2004)
   PUBMED   14970218
REFERENCE   4  (bases 1 to 2448)
  AUTHORS   Hedvat,C.V., Yao,J., Sokolic,R.A. and Nimer,S.D.
  TITLE     Myeloid ELF1-like factor is a potent activator of interleukin-8
            expression in hematopoietic cells
  JOURNAL   J Biol Chem 279 (8), 6395-6400 (2004)
   PUBMED   14625302
  REMARK    Erratum:[J Biol Chem. 2006 Mar 31;281(13):8996]
REFERENCE   5  (bases 1 to 2448)
  AUTHORS   Lacorazza,H.D., Miyazaki,Y., Di Cristofano,A., Deblasio,A.,
            Hedvat,C., Zhang,J., Cordon-Cardo,C., Mao,S., Pandolfi,P.P. and
            Nimer,S.D.
  TITLE     The ETS protein MEF plays a critical role in perforin gene
            expression and the development of natural killer and NK-T cells
  JOURNAL   Immunity 17 (4), 437-449 (2002)
   PUBMED   12387738
REFERENCE   6  (bases 1 to 2448)
  AUTHORS   Aryee,D.N., Petermann,R., Kos,K., Henn,T., Haas,O.A. and Kovar,H.
  TITLE     Cloning of a novel human ELF-1-related ETS transcription factor,
            ELFR, its characterization and chromosomal assignment relative to
            ELF-1
  JOURNAL   Gene 210 (1), 71-78 (1998)
   PUBMED   9524226
REFERENCE   7  (bases 1 to 2448)
  AUTHORS   Miyazaki,Y., Sun,X., Uchida,H., Zhang,J. and Nimer,S.
  TITLE     MEF, a novel transcription factor with an Elf-1 like DNA binding
            domain but distinct transcriptional activating properties
  JOURNAL   Oncogene 13 (8), 1721-1729 (1996)
   PUBMED   8895518
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            [WARNING] On Oct 18, 2024 this sequence was replaced by
            NM_001191735.2.
            
            On Jul 17, 2010 this sequence version replaced XM_229125.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.68753.1,
                                           SRR26643284.21629.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                JAXUCZ010000021.1  132478413-132478484 c
            73-244              JAXUCZ010000021.1  132475317-132475488 c
            245-337             JAXUCZ010000021.1  132474885-132474977 c
            338-526             JAXUCZ010000021.1  132473375-132473563 c
            527-610             JAXUCZ010000021.1  132472409-132472492 c
            611-803             JAXUCZ010000021.1  132472132-132472324 c
            804-1181            JAXUCZ010000021.1  132471138-132471515 c
            1182-2448           JAXUCZ010000021.1  132468539-132469805 c
FEATURES             Location/Qualifiers
     source          1..2448
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq36"
     gene            1..2448
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /note="E74 like ETS transcription factor 4"
                     /db_xref="GeneID:302811"
                     /db_xref="RGD:1560743"
     CDS             1..1983
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /note="E74-like factor 4 (ets domain transcription
                     factor)"
                     /codon_start=1
                     /product="ETS-related transcription factor Elf-4"
                     /protein_id="NP_001178664.1"
                     /db_xref="GeneID:302811"
                     /db_xref="RGD:1560743"
                     /translation="MAIALQPSDLVFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPEL
                     VHLYSGLDLDEVHSGIIRDRTLCMTQDQILEGSILLTDDNVSTSNNSSSTEVLFNVAT
                     PSDVLDEKQIFSTPEVLPDSNSVQAINLPNFLLSTPEPDDPKKTSDAGDQKEYSLEEV
                     SREENLRKIGKSRKRNRKTKNNRSTSPVTDPSVPIRKKSKDGKGSTIYLWEFLLALLQ
                     DRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGIL
                     AKVEGQRLVYQFKEMPKDLVVIDDEEESTETPEDSSQASTSSTPSTSTTRRPSSRVVT
                     RASPEDKDSPSWEKPKVEHTGLQPSASLELGLSVDEEVPTTSTMIVSPLQSQAKPAKT
                     VSTSAPSNIHLGVAPVGPGSTVTLQTIPLTTVLTNGPPAGTTAPAQLVLQSVPQVSTF
                     KDTLTLQTSFPLNASLQENQVATQGTPLILSGLPQLLAGANHQSNPVTSQVIGAGSAG
                     PSSQPPGTVIAAFIRTSNGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLREL
                     LRDQAHLQPLQSQALSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSSSGSLLVT
                     EPNMTTSGSLLTRSPTQAPFSPFNPTSLIKMEPHDI"
     exon            1..72
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
     exon            73..244
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
     exon            245..337
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
     exon            338..526
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
     exon            527..610
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
     exon            611..803
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
     exon            804..1181
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..2448
                     /gene="Elf4"
                     /gene_synonym="RGD1560743"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctattg ccctgcagcc cagcgatctg gtctttgagt tcgcaagcaa cgggatggat
       61 gatatccacc agctggaaga cccttcagtg ttcccagctg tgatcgtgga acaggtcccc
      121 tatcctgaat tagtacatct gtactcagga ctggatctgg atgaagtcca cagtggcatc
      181 ataagggaca ggaccttgtg catgacacag gatcagatct tagaaggcag tattttgctg
      241 acagatgaca atgtgtccac ctcaaataac tcgtcatcta ctgaagtcct attcaatgtg
      301 gcaactccca gtgatgtcct ggatgagaag cagatcttca gcacaccgga agtgcttcca
      361 gactccaact ctgttcaggc catcaatctg cccaacttcc tgctttccac ccctgaacct
      421 gatgacccaa agaagacaag tgatgctggt gaccagaagg agtattctct ggaggaggtt
      481 tccagagagg aaaatcttag gaagattggg aagtcacgga agagaaaccg aaagacaaag
      541 aacaaccgaa gtacctcacc tgtcactgac cccagcgtgc ccatccggaa gaaatccaag
      601 gatggcaaag gcagcaccat ttatctgtgg gagttcctcc tggctcttct gcaagataga
      661 aacacctgcc ccaaatacat caagtggacg cagcgagaga aaggcatctt caagttggtg
      721 gactccaaag ctgtgtccaa gctgtggggc aagcagaaaa acaaacctga tatgaactat
      781 gagactatgg ggcgggccct aagatattac tatcagagag gaatcctggc caaagtggaa
      841 gggcagaggc tggtatacca gttcaaggag atgcctaagg acttggtggt gattgacgat
      901 gaggaggaga gtactgaaac accagaagac tcttcccagg cctctacttc ctccacaccc
      961 tctaccagta ccacccggag acccagctcc agggttgtaa ccagagcctc ccccgaggac
     1021 aaggatagtc cttcctggga gaagccaaag gttgaacaca ctggtctcca gccctctgca
     1081 agcctggagt taggattatc tgtggatgag gaggtcccga ctacctccac catgattgtc
     1141 agtccactac agagccaggc caagcccgcc aaaactgtga gtacttcagc gcccagtaac
     1201 atccacctag gagtagcccc agtggggccc ggctccacgg ttaccctgca gaccatccca
     1261 ctgactacgg tgctgaccaa tgggcctcct gccggtacta ctgctcctgc tcagctcgtt
     1321 cttcagagtg tcccacaggt gtcaacgttc aaggacaccc tcactttgca gacttccttt
     1381 cccctgaatg ccagtttgca agagaaccag gtggcaaccc aagggacccc attgatcctc
     1441 agtggtctcc cccaacttct ggccggggcc aaccatcaga gcaacccggt aacatcccag
     1501 gtcataggtg ctgggtcagc aggacccagc tctcagcccc ctgggactgt cattgctgcc
     1561 tttatcagga cttctaatgg cacttcagtg cctgtggtta aggaggggcc cttgaggtcc
     1621 tcttcatatg tgcagggtgt ggtaactggg gccccagtgg aggggctgtt ggtccctgaa
     1681 gagaccctaa gagagctcct gagagatcag gctcatcttc agccacttca gagtcaggcg
     1741 ctctcaagag gttcccataa cctgagcctt gtggggaacc agactttatc tccccctagc
     1801 caccccactg ttgggctaac tccggtggct gaacttgagc tctcatccag ctcagggtcc
     1861 ctgttggtaa ctgagcctaa tatgaccaca tctgggagcc tgctgaccag atcccccacc
     1921 caggcccctt tctccccatt caatcccact tccctcatta agatggagcc ccatgacata
     1981 taaacaaagg gatcaaaagt atgaccctcc ggggcaaaat tgtgaaacat tttcgtgtgg
     2041 acttaagtag agtacccgcc cttacatcta gtgcggtgag agaaaatttg attccaagtt
     2101 ccctagacct atctggcgtc gttatgacca aagtacgccc agctcaagca tcgctggcat
     2161 cagacatggc cttcaagagc actagggagt ggataggctc ttgaaaggat aatgagatga
     2221 cttggtgatg gagggacatc cacaagccag gaagccgctt gtggtcagag ctggtcagct
     2281 tcccaagaag agttaagtct ggtcatactt cgctatctat attccttaca cagggaactt
     2341 accatccgat atgtgaatat cttcttcgta tgcatttgtg tgcacttgtg gttctgtatc
     2401 ttcatttctt tggggaggat gggatttaga tgtcaggtct tttcttcg
//
