LOCUS       NM_001024768            1976 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus E74 like ETS transcription factor 3 (Elf3), mRNA.
ACCESSION   NM_001024768 XM_222659
VERSION     NM_001024768.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1976)
  AUTHORS   Wang,J., Shen,X., Liu,J., Chen,W., Wu,F., Wu,W., Meng,Z., Zhu,M.
            and Miao,C.
  TITLE     High glucose mediates NLRP3 inflammasome activation via
            upregulation of ELF3 expression
  JOURNAL   Cell Death Dis 11 (5), 383 (2020)
   PUBMED   32439949
  REMARK    GeneRIF: High glucose mediates NLRP3 inflammasome activation via
            upregulation of ELF3 expression.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1976)
  AUTHORS   Kageyama,S., Liu,H., Nagata,M. and Aoki,F.
  TITLE     The role of ETS transcription factors in transcription and
            development of mouse preimplantation embryos
  JOURNAL   Biochem Biophys Res Commun 344 (2), 675-679 (2006)
   PUBMED   16630543
REFERENCE   3  (bases 1 to 1976)
  AUTHORS   Brown,C., Gaspar,J., Pettit,A., Lee,R., Gu,X., Wang,H., Manning,C.,
            Voland,C., Goldring,S.R., Goldring,M.B., Libermann,T.A.,
            Gravallese,E.M. and Oettgen,P.
  TITLE     ESE-1 is a novel transcriptional mediator of angiopoietin-1
            expression in the setting of inflammation
  JOURNAL   J Biol Chem 279 (13), 12794-12803 (2004)
   PUBMED   14715662
REFERENCE   4  (bases 1 to 1976)
  AUTHORS   Cabral,A., Fischer,D.F., Vermeij,W.P. and Backendorf,C.
  TITLE     Distinct functional interactions of human Skn-1 isoforms with Ese-1
            during keratinocyte terminal differentiation
  JOURNAL   J Biol Chem 278 (20), 17792-17799 (2003)
   PUBMED   12624109
REFERENCE   5  (bases 1 to 1976)
  AUTHORS   Kim,J.H., Wilder,P.J., Hou,J., Nowling,T. and Rizzino,A.
  TITLE     Activation of the murine type II transforming growth factor-beta
            receptor gene: up-regulation and function of the transcription
            factor Elf-3/Ert/Esx/Ese-1
  JOURNAL   J Biol Chem 277 (20), 17520-17530 (2002)
   PUBMED   11893733
REFERENCE   6  (bases 1 to 1976)
  AUTHORS   Ng,A.Y., Waring,P., Ristevski,S., Wang,C., Wilson,T., Pritchard,M.,
            Hertzog,P. and Kola,I.
  TITLE     Inactivation of the transcription factor Elf3 in mice results in
            dysmorphogenesis and altered differentiation of intestinal
            epithelium
  JOURNAL   Gastroenterology 122 (5), 1455-1466 (2002)
   PUBMED   11984530
REFERENCE   7  (bases 1 to 1976)
  AUTHORS   Brembeck,F.H., Opitz,O.G., Libermann,T.A. and Rustgi,A.K.
  TITLE     Dual function of the epithelial specific ets transcription factor,
            ELF3, in modulating differentiation
  JOURNAL   Oncogene 19 (15), 1941-1949 (2000)
   PUBMED   10773884
REFERENCE   8  (bases 1 to 1976)
  AUTHORS   Neve,R., Chang,C.H., Scott,G.K., Wong,A., Friis,R.R., Hynes,N.E.
            and Benz,C.C.
  TITLE     The epithelium-specific ets transcription factor ESX is associated
            with mammary gland development and involution
  JOURNAL   FASEB J 12 (14), 1541-1550 (1998)
   PUBMED   9806763
REFERENCE   9  (bases 1 to 1976)
  AUTHORS   Oettgen,P., Alani,R.M., Barcinski,M.A., Brown,L., Akbarali,Y.,
            Boltax,J., Kunsch,C., Munger,K. and Libermann,T.A.
  TITLE     Isolation and characterization of a novel epithelium-specific
            transcription factor, ESE-1, a member of the ets family
  JOURNAL   Mol Cell Biol 17 (8), 4419-4433 (1997)
   PUBMED   9234700
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097980.1.
            
            On Jun 10, 2005 this sequence version replaced XM_222659.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097980.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1976
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..1976
                     /gene="Elf3"
                     /note="E74 like ETS transcription factor 3"
                     /db_xref="GeneID:304815"
                     /db_xref="RGD:1310687"
     exon            1..87
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     exon            88..255
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..1283
                     /gene="Elf3"
                     /note="E74-like factor 3"
                     /codon_start=1
                     /product="ETS-related transcription factor Elf-3"
                     /protein_id="NP_001019939.1"
                     /db_xref="GeneID:304815"
                     /db_xref="RGD:1310687"
                     /translation="MAATCEISNVFSNYFNAMYSSEDPTLAPAPLTTFGTEDFVLTLN
                     NQHMSPEGPVGCVGPQTRSQRDRTEPPAVLHLAEKASWTGERPQFWSKTQVLDWISYQ
                     VEKNKYDASSIDFSRCDMDGATLCNCALEELRLVFGPLGDQLHAQLRDLTSSSSDELS
                     WIIELLEKDGMTFQEGLGDSGPFDQGSPFAQELLDDGRQASPYYGSSYGPGAPSPGSS
                     DFSTSGTDTPQSSHSSDSGGSDVDLDLTDSKVFPRDGFPDYKKGEPKHGKRKRGRPRK
                     LSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEA
                     VAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVGE
                     SQN"
     exon            256..549
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     exon            550..645
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     exon            646..765
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     exon            766..855
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     exon            856..972
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1168
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1953
                     /gene="Elf3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggagcctt ccaccgctta gatttcttcc cttcctgtgg cctcagaagc ctgcttacct
       61 gcctgccaca ccggaccctg acactcgggg gcctcatggc tgccacctgt gagatcagca
      121 acgtttttag caactacttc aacgccatgt acagttcaga agaccccacc ctggctcctg
      181 ctcctctgac tacttttggc actgaagact ttgtgttgac cctgaacaac caacacatgt
      241 ccccagaagg tccagtaggt tgtgtaggac ctcagacaag atcccaaagg gacagaactg
      301 agcctccggc tgtactccac cttgcagaga aggcaagctg gaccggagag cggccccagt
      361 tctggtcgaa gacccaggta ctggattgga tcagctacca agtggagaag aacaagtatg
      421 atgccagttc cattgacttc tcgcgctgcg acatggacgg cgccaccctc tgcaactgtg
      481 cgctggagga gctgcgacta gtctttggcc ctctgggaga ccaactccat gcccagcttc
      541 gggacctcac ctccagctct tctgatgaac ttagttggat catcgagctg ctggagaagg
      601 acggcatgac cttccaagag ggcctaggag actcgggtcc ctttgaccag ggaagccctt
      661 ttgcccagga gctactggat gatggccgtc aggccagccc ctactacggc agttcctatg
      721 gccctggagc gccctctcca ggtagctctg atttctccac ttcagggacc gatactcccc
      781 agagttccca ctcctctgac tccggtggaa gtgatgtgga cctggacctc accgatagca
      841 aggtcttccc tagagatggc tttcctgact ataagaaggg agaacccaag catggaaaga
      901 ggaaacgggg gcgtccccga aagctgagca aagaatactg ggactgtctg gagggcaaga
      961 agagcaagca tgcccccaga ggtactcacc tgtgggagtt catccgggac attcttatcc
     1021 accctgagct caacgaaggc ctcatgaaat gggagaaccg gcacgagggc gttttcaagt
     1081 ttcttcgttc agaggctgtg gcccaactat ggggccaaaa gaagaagaat agcaacatga
     1141 cctatgagaa gctgagccgg gccatgaggt actactacaa acgggagatc ctggaacggg
     1201 tggatggccg tcggctcgtc tacaagtttg gcaagaactc cagtggctgg aaggaagaag
     1261 aggttggaga gagtcagaat taagggtcag ggctggcccc ggacctgatt caggcatgaa
     1321 ctccagaact gaagccttcc tggaaggaca ggcaggcctg aaggcccctc gatgtggatg
     1381 tgtttccctg tgtgctgcag agaggaggaa cctgttgggt gtggcctctg cagtatcctg
     1441 agcctttggc ctctcctcgc cctcttggga ttacgagccc ccgggtttga cttcacaaac
     1501 tctccagctg tgaatccagt tccttccagt cccaacgttg actgcagaag agattcacct
     1561 gcagatgcct gggctcagcc aaggaggctg gagagactgt gggaggagac tacagggaca
     1621 gaggggacag gattgtgttc tctagagctt cttggactgg cttccacctc tctgctcagt
     1681 actcaggctc cacagacaca ggggtcagag caaccctaat ttatgtgcta taaatattcc
     1741 aggtgtatat agagagctat tttttctaaa gcgtttcccc ctccctgttc ttctctactg
     1801 agtgctggtg gccagaccaa ttgttctagg gcccctaact ggaccaggga gaagtagggt
     1861 gataccagag tccccaagat ggggctcttg gacccccttt cctgtgattg gaggttgaaa
     1921 cctccaataa agcgccttct gggctttttc taaaaaaaaa aaaaaaaaaa aaaaaa
//
