LOCUS       NM_001033909            3199 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus E74 like ETS transcription factor 2 (Elf2),
            transcript variant 1, mRNA.
ACCESSION   NM_001033909 XM_574938
VERSION     NM_001033909.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Gronli J, Dagestad G, Milde AM, Murison R and Bramham CR.
  TITLE     Post-transcriptional effects and interactions between chronic mild
            stress and acute sleep deprivation: regulation of translation
            factor and cytoplasmic polyadenylation element-binding protein
            phosphorylation
  JOURNAL   Behav Brain Res 235 (2), 251-262 (2012)
   PUBMED   22917528
  REMARK    GeneRIF: The eEF2 phosphorylation was elevated in all brain regions
            after sleep deprivation
REFERENCE   2  (bases 1 to 3199)
  AUTHORS   Fujisawa T, Moriwaki A, Matsushita M, Tomizawa K and Matsui H.
  TITLE     Colocalization of oxytocin and phosphorylated form of elongation
            factor 2 in the rat hypothalamus
  JOURNAL   Acta Med Okayama 61 (3), 161-166 (2007)
   PUBMED   17593952
  REMARK    GeneRIF: Oxt is colocalized with the phosphorylated form of Elf2 in
            the hypothalamus.
REFERENCE   3  (bases 1 to 3199)
  AUTHORS   Cho JY, Akbarali Y, Zerbini LF, Gu X, Boltax J, Wang Y, Oettgen P,
            Zhang DE and Libermann TA.
  TITLE     Isoforms of the Ets transcription factor NERF/ELF-2 physically
            interact with AML1 and mediate opposing effects on AML1-mediated
            transcription of the B cell-specific blk gene
  JOURNAL   J Biol Chem 279 (19), 19512-19522 (2004)
   PUBMED   14970218
REFERENCE   4  (bases 1 to 3199)
  AUTHORS   Oettgen P, Akbarali Y, Boltax J, Best J, Kunsch C and Libermann TA.
  TITLE     Characterization of NERF, a novel transcription factor related to
            the Ets factor ELF-1
  JOURNAL   Mol Cell Biol 16 (9), 5091-5106 (1996)
   PUBMED   8756667
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC083585.1.
            
            On Oct 4, 2005 this sequence version replaced XM_574938.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083585.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3199              BC083585.1         153-3351
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q26"
     gene            1..3199
                     /gene="Elf2"
                     /note="E74 like ETS transcription factor 2"
                     /db_xref="GeneID:361944"
                     /db_xref="RGD:1310585"
     exon            1..88
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     exon            89..310
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             239..2014
                     /gene="Elf2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ETS-related transcription factor Elf-2; E74-like factor 2"
                     /codon_start=1
                     /product="ETS-related transcription factor Elf-2 isoform
                     1"
                     /protein_id="NP_001029081.1"
                     /db_xref="GeneID:361944"
                     /db_xref="RGD:1310585"
                     /translation="MASAVVGGGGSVLELSSNGVENQEGGDTVPEFPAVIVEPVPSAR
                     LEQGYAAQVLVYDDETYMMQDVAEEQEVETENSETVEASVHSSNAHCTDKTIEAAEAL
                     LHMESPTCLRDSRSPVEVFVPPCISTPEFIHAAMRPDVITETVVEVSTEESEPMDASP
                     IPTSPDSHEPMKKKKVGRKPKTQQSPVSNGSPELGVKKKAREGKGNTTYLWEFLLDLL
                     QDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGI
                     LAKVEGQRLVYQFKDMPKNIVVIDDDKSETCPEDLAAAADDKSLERVSLSAESLLKAA
                     TAVRGGKNSSPMNCSRAEKGVTRVVNITSPAHDASSRCPTTTAPVSAAAAPRTVRVAM
                     QVPVVMTSLGQKISTVAVQSVNAGTPLITSTSPATASSPKVVIQTVPTVMPASAENGD
                     RITMQPAKIITIPATQLAQCQLQTKSNLTGSGSISLVGTPLAVRALTPVSIAHGTPVM
                     RLSVPAQQASGQTPPRVISAVIKGPEVKSEAKKQEHDVKTLQLVEEKGADGNKTVTHV
                     VVVSAPSAIALPVTMKTEGLVTCEK"
     exon            311..476
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     exon            477..590
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     exon            591..764
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     exon            765..851
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     exon            852..1044
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1395
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..3172
                     /gene="Elf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtagctcca gagagctgct ggtttagagt tcagctcttg ggagtgtgga aacggtgaag
       61 gatgcttaga ctacttaacc gtcaaactac cctctggtta atcatcttta gaagactgga
      121 cttctggatg tctactccat cactattgaa ttagaacatg aaaccgataa ccctggcaat
      181 catctgagcc gtaattacat tgattcgcag cgttcgaaac ttgctcaggg aagacgcgat
      241 ggcatcagca gtggttggcg gcggaggctc tgttctggag ctttccagca atggagtaga
      301 aaatcaagag ggaggggaca cggtccctga atttccggca gtgattgtgg agcccgtccc
      361 cagtgcgagg ttagagcagg gctacgctgc ccaggtgctg gtgtatgacg atgagactta
      421 catgatgcag gatgtggcgg aagaacaaga agttgagacg gagaattcag aaacagtgga
      481 agcatcagtt cacagcagta atgcacactg tacggataag accattgaag ctgctgaagc
      541 cctgcttcat atggagtctc ctacctgctt gagggattca agaagtcccg tggaagtgtt
      601 tgtccctcct tgtatatcaa ctccagagtt tatccatgct gcgatgaggc cagatgtcat
      661 tacggagact gtagtggagg tgtcaacaga ggagtctgaa ccaatggatg cctcgcctat
      721 ccctacttca ccagacagcc acgaaccaat gaaaaagaag aaagttggcc gtaaaccaaa
      781 gacccagcag tcaccagttt ccaatgggtc tcctgagtta ggagtcaaga agaaagccag
      841 agaaggaaaa ggaaacacaa cctatctgtg ggagtttctt ttagatctgc ttcaagataa
      901 aaatacttgt cccaggtata ttaaatggac tcagagagaa aagggcatat tcaagctggt
      961 ggactcaaag gctgtctcga agctctgggg aaagcataag aacaaaccag acatgaacta
     1021 tgaaactatg gggcgagctc tgagatacta ctaccaaagg ggaattcttg caaaggttga
     1081 aggacagagg ctcgtatatc agttcaagga catgcccaaa aacatagtgg tcattgatga
     1141 tgacaaaagt gagacttgcc cggaagactt ggcagcagct gctgatgaca agtctttaga
     1201 acgagtgtca ctatctgcag aaagtctcct gaaggcagcg actgccgtcc gaggtgggaa
     1261 aaactcatct cctatgaact gctccagagc agagaagggt gtgactagag ttgtgaacat
     1321 cacttcccct gctcacgatg cttcatccag gtgtcctacc accacagcac ccgtgtcagc
     1381 agcagcagct ccaaggacag ttcgtgtggc aatgcaagtc cctgtggtaa tgacatcact
     1441 gggtcaaaag atttccactg tggcagttca gtcagtcaat gcaggcacac cattaataac
     1501 cagcaccagt ccagctacag ccagctctcc aaaagtagtc atccagacgg tcccgactgt
     1561 gatgccagcc tccgctgaga atggagacag aatcaccatg cagcctgcca agattatcac
     1621 catccccgct acccagcttg cacagtgtca gctgcagaca aagtcaaatc tgactgggtc
     1681 aggaagcatt agccttgttg gaacccccct ggctgtgaga gcgctcaccc ctgtttcaat
     1741 agcccacggt acacctgtga tgagactatc tgtgcccgct cagcaggctt ctggccagac
     1801 tcctcctcga gttatcagtg cggtcataaa agggccagag gttaaatcag aagccaaaaa
     1861 gcaggaacac gatgtgaaaa ctttgcagct ggtagaagaa aagggggcag acggaaataa
     1921 gacagtaacc catgtagtgg ttgtcagtgc gccctctgct atcgcccttc ctgtgactat
     1981 gaaaaccgaa gggctggtga cgtgtgagaa ataagcaagc tcccagggac ttcagactgt
     2041 tagtgttgta ctgacagaca tttgcaaggg aagtcatcgg gaaaaggcag aggaggactt
     2101 tcaaacaact gtgcatagaa gaaagcaatc agacttactg gaaataaatt acctatccca
     2161 tgtttcagtg ggaagtgaac tacacattga gatgctgaca gaaaactgcc tcttaaagta
     2221 agaacaactg aaccctcaat aagaaaaaag actgaaaggg accaagcagc tcactacaat
     2281 ctcccgttac actaagagtt ggaacactaa cacctgtaag aggttacata gttttcagag
     2341 gggcggggtt gggatgggtg atgtcattgt tacaaatagc attttttgat gcattttata
     2401 tgcataccag caattagcac tgggctctcg cagtgctcac ttaactggtg ctatgtgaag
     2461 actctgctaa tacaggtatt ctagaatgtg aactgagtga tccaaaagct tcacagagag
     2521 agaggatagc aagatctagt gcgcttttgt ttgtttgttt tgttttattt tttgattttg
     2581 aatatatata tatatatatc atagcttaag ctgttttaaa acaaaggcct tagactaatt
     2641 ttcagtttcc tttcttgaaa taagctaatg gcttgtgtaa agctttttta ttaaaagaaa
     2701 aattttaaaa atcttgtacc tagcacagta ttgttataga gtttccatgt aacattttct
     2761 atggtagttt aagtctgtcg gtttcttact tgtgaagaga ttaacagttg gctctggccc
     2821 ttgactgtac catccctgcg ccgctcaagt caccctgccg tccgtccgtc cgtccgtccg
     2881 tccttccgtc cgcagacaca ccggtatcag ttcttctgtc atttgacatt caggctcgca
     2941 tgaactcgcc aggtagctct gatacctggt gtttgtttcc tttctcattc tttttccttt
     3001 tctccctttt ttctcttttt cttttttagt tgacatttaa gagggaaagt accagtgttc
     3061 agatttgaac tataatagtt tgtatattca acatttgaag tatattctat tttgttgtac
     3121 tcttgtttca aagtgtattc aagtaggttt tgaaatatag aagtgaaatt taaaaaaaaa
     3181 aaaaaaaaaa aaaaaaaaa
//
