LOCUS       NM_053520               2504 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus E74 like ETS transcription factor 1 (Elf1), mRNA.
ACCESSION   NM_053520
VERSION     NM_053520.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2504)
  AUTHORS   Song,H., Suehiro,J., Kanki,Y., Kawai,Y., Inoue,K., Daida,H.,
            Yano,K., Ohhashi,T., Oettgen,P., Aird,W.C., Kodama,T. and Minami,T.
  TITLE     Critical role for GATA3 in mediating Tie2 expression and function
            in large vessel endothelial cells
  JOURNAL   J Biol Chem 284 (42), 29109-29124 (2009)
   PUBMED   19674970
REFERENCE   2  (bases 1 to 2504)
  AUTHORS   Nishiyama,A., Xin,L., Sharov,A.A., Thomas,M., Mowrer,G., Meyers,E.,
            Piao,Y., Mehta,S., Yee,S., Nakatake,Y., Stagg,C., Sharova,L.,
            Correa-Cerro,L.S., Bassey,U., Hoang,H., Kim,E., Tapnio,R., Qian,Y.,
            Dudekula,D., Zalzman,M., Li,M., Falco,G., Yang,H.T., Lee,S.L.,
            Monti,M., Stanghellini,I., Islam,M.N., Nagaraja,R., Goldberg,I.,
            Wang,W., Longo,D.L., Schlessinger,D. and Ko,M.S.
  TITLE     Uncovering early response of gene regulatory networks in ESCs by
            systematic induction of transcription factors
  JOURNAL   Cell Stem Cell 5 (4), 420-433 (2009)
   PUBMED   19796622
REFERENCE   3  (bases 1 to 2504)
  AUTHORS   Geng,Y., Laslo,P., Barton,K. and Wang,C.R.
  TITLE     Transcriptional regulation of CD1D1 by Ets family transcription
            factors
  JOURNAL   J Immunol 175 (2), 1022-1029 (2005)
   PUBMED   16002702
REFERENCE   4  (bases 1 to 2504)
  AUTHORS   Cho,J.Y., Akbarali,Y., Zerbini,L.F., Gu,X., Boltax,J., Wang,Y.,
            Oettgen,P., Zhang,D.E. and Libermann,T.A.
  TITLE     Isoforms of the Ets transcription factor NERF/ELF-2 physically
            interact with AML1 and mediate opposing effects on AML1-mediated
            transcription of the B cell-specific blk gene
  JOURNAL   J Biol Chem 279 (19), 19512-19522 (2004)
   PUBMED   14970218
REFERENCE   5  (bases 1 to 2504)
  AUTHORS   Carpino,N., Turner,S., Mekala,D., Takahashi,Y., Zang,H.,
            Geiger,T.L., Doherty,P. and Ihle,J.N.
  TITLE     Regulation of ZAP-70 activation and TCR signaling by two related
            proteins, Sts-1 and Sts-2
  JOURNAL   Immunity 20 (1), 37-46 (2004)
   PUBMED   14738763
REFERENCE   6  (bases 1 to 2504)
  AUTHORS   Nishiyama,C., Takahashi,K., Nishiyama,M., Okumura,K., Ra,C.,
            Ohtake,Y. and Yokota,T.
  TITLE     Splice isoforms of transcription factor Elf-1 affecting its
            regulatory function in transcription-molecular cloning of rat Elf-1
  JOURNAL   Biosci Biotechnol Biochem 64 (12), 2601-2607 (2000)
   PUBMED   11210123
REFERENCE   7  (bases 1 to 2504)
  AUTHORS   Oettgen,P., Akbarali,Y., Boltax,J., Best,J., Kunsch,C. and
            Libermann,T.A.
  TITLE     Characterization of NERF, a novel transcription factor related to
            the Ets factor ELF-1
  JOURNAL   Mol Cell Biol 16 (9), 5091-5106 (1996)
   PUBMED   8756667
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB782606.1, AB030215.1 and AB030216.1.
            
            On Feb 14, 2005 this sequence version replaced NM_053520.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB046531.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132264, SAMD00132266
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                CB782606.1         56-80
            26-737              AB030215.1         2-713
            738-2079            AB030216.1         399-1740
            2080-2504           AB030215.1         2056-2480
FEATURES             Location/Qualifiers
     source          1..2504
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q12"
     gene            1..2504
                     /gene="Elf1"
                     /note="E74 like ETS transcription factor 1"
                     /db_xref="GeneID:85424"
                     /db_xref="RGD:620697"
     exon            1..303
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             232..2079
                     /gene="Elf1"
                     /note="E74-like factor 1 (ets domain transcription
                     factor)"
                     /codon_start=1
                     /product="ETS-related transcription factor Elf-1"
                     /protein_id="NP_445972.2"
                     /db_xref="GeneID:85424"
                     /db_xref="RGD:620697"
                     /translation="MAAVVQQNDLVFDFASNVMEDEQQLGDPAIFPAVIVEHVPGADI
                     LNGYAGLACVEEPNDMITESSLDVAEEEIIEDDDDDITLTVEASCHNGDETIETIGAA
                     EALLNMDSPGPVLDEKRINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQESNA
                     DSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKSKDGKGNTIYLWEFLLALLQ
                     DKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGIL
                     AKVEGQRLVYQFKEMPKDLIYIDDEGPSSSTESSDQSLSSTTTSSRNQANRTRMSSSP
                     GIKGGATTILKPGNPKVAKPKDTVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQ
                     AIPEEATITSTMQEEAAGSSVQGIRTIQASTQVPVVVSPGNQQLHTVTLQTVPLTTVI
                     ASTDPSSGAGPQKFILQAIPSSQPMTVLKENVLLQSQKPGSPPSIVFSPTPVQQVLTG
                     SVQSLGNGAVSMASPPNFSATAPVVTFSRSSQLAAHPPGTVITSVIKAQETKTPKAEV
                     EKKAEGHLNGDPEEIEQQPQPYVMVVSSSNGFSSQVAITQNELLEPSSF"
     exon            304..484
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
     exon            485..592
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
     exon            593..757
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
     exon            758..841
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
     exon            842..1034
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1481
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..2504
                     /gene="Elf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcagggacaa gaagacctag tgaatgattt cagaaaaagt gcctgtttgc ttaggatgtc
       61 agtgcaccaa gcaaatctga agcactcctt tcgctgagga gcgtcctgtc tgcaataact
      121 tcacagacct gccccagagg ctttcctcga attcccttgc gccttaccta ctgctccaga
      181 ctggaagctg cttgggactt tttcacgtgg atctaagggg aatgctttac tatggctgct
      241 gttgtccaac agaacgacct agtgtttgac tttgcaagca acgtcatgga ggatgaacag
      301 cagcttggcg accctgccat atttcctgct gtcattgtgg aacatgttcc tggtgctgat
      361 attctcaatg gttatgccgg gctagcctgt gtggaagaac ccaatgacat gattactgag
      421 agctctctgg atgttgctga agaagaaatc atagaggatg acgatgacga catcaccctt
      481 acagtcgagg cctcttgtca caatggagat gagaccattg agaccattgg ggctgctgag
      541 gcgctcctca atatggactc tcctggccct gtactggatg aaaagcgaat caataataat
      601 atatttagct cttctgaaga tgacatcgtt gccccaatca cccacgtgtc tgtcacactg
      661 gatgggattc ctgaggtgat ggaaacccag caagtgcaag agtccaatgc agactcccct
      721 ggagcctcct ccccagagca gcccaagaga aagaagggaa gaaaaacaaa accaccacga
      781 ccagattccc cggccactac accaaatata tctgtgaaaa agaaaagtaa agacgggaag
      841 ggaaacacaa tttacctttg ggagttttta ctggctctgc ttcaggacaa agctacctgt
      901 cctaagtaca tcaaatggac acagcgagaa aaaggcattt ttaagttggt cgactctaaa
      961 gctgtgtcca gattatgggg gaagcacaaa aacaaacctg acatgaacta tgagaccatg
     1021 gggcgagcac tcaggtacta ttaccaaaga ggtattcttg caaaagtgga aggtcagcgc
     1081 ttggtgtatc agtttaaaga aatgccaaaa gaccttatct acatagacga tgagggtcca
     1141 agttccagca cagagtcttc agatcagtcc ttatcttcaa cgaccacttc tagtcggaat
     1201 caagcaaacc gaacaagaat gtcttcaagt ccaggaataa aaggaggggc cactacaatt
     1261 ctaaaaccag ggaatcctaa agttgcaaaa cccaaagaca ccgtggaagt tgggcagcct
     1321 tcagaagttt tgaggacagt gcagccctca caggctccct atcctaccca gctcttccgg
     1381 actgtccatg tggtacagcc agtacaagcc atccccgaag aagcaaccat aaccagcacc
     1441 atgcaggagg aagctgcagg ttcttcagtt cagggcatta ggacgataca ggcttcaacc
     1501 caggttccag tagtcgtgtc tcctggcaac caacagctac atacagtaac actccagaca
     1561 gtgccactca caacggttat agccagcaca gacccgtcat caggtgcagg gccgcagaaa
     1621 tttattttac aagccattcc atcatcacag cccatgacag tactgaaaga aaacgtcctg
     1681 ctacagtcac agaagccggg ctctcctcct tcaatcgtct tcagccctac cccagtacag
     1741 caggtcctta cgggcagcgt tcagtccctt ggcaatggag ctgtcagtat ggcttcacct
     1801 ccaaacttca gtgctaccgc acctgtggtg actttctctc ggagctcaca gctggctgca
     1861 cacccaccag gcaccgtgat cacgtctgtt atcaaagctc aggaaacaaa aactcctaaa
     1921 gcagaggtgg agaaaaaggc tgaaggtcat ttgaatggag accctgagga aattgaacag
     1981 cagccccagc cttatgtgat ggtggtgtcc agttcaaatg ggttttcctc tcaggtagcc
     2041 atcacacaga atgaactgct agagcccagc tctttttaat tactacacca aaggaattat
     2101 gggtggttat tttttttaat tgaactcatt tttggttgtc tgaccataac atgatttttt
     2161 tctaagataa atccacagaa gatcttaatt ttgtaattgt taaaaacagt gacctttgcc
     2221 tttgctagat aaggaggaaa acccatgtat gtctcctctc taaatgtttc agaactgagt
     2281 tgtgaaggag caggaatttt atacgatgaa gaaattcttg aaattttttt cagttgctat
     2341 atcataagta tttttaaagt ttcttttcta gcttgacact gtattagctt cctgaattgt
     2401 tcgaaaatac tacttaaata tacgtcaaga ggaaatttat ataggaaaca ttttcattcc
     2461 acttgtataa tttaagtctt gactcttttc agatgcaaga aact
//
