LOCUS       NM_172324               1597 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus ELAV like RNA binding protein 3 (Elavl3), mRNA.
ACCESSION   NM_172324
VERSION     NM_172324.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Bitel CL, Perrone-Bizzozero NI and Frederikse PH.
  TITLE     HuB/C/D, nPTB, REST4, and miR-124 regulators of neuronal cell
            identity are also utilized in the lens
  JOURNAL   Mol Vis 16, 2301-2316 (2010)
   PUBMED   21139978
  REMARK    GeneRIF: The predominant expression of REST4, HuB/C/D and nPTB in
            post-mitotic fiber cells, together with miR-124 expression in
            vertebrate lenses, was shown.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1597)
  AUTHORS   Fornaro M, Raimondo S, Lee JM and Giacobini-Robecchi MG.
  TITLE     Neuron-specific Hu proteins sub-cellular localization in primary
            sensory neurons
  JOURNAL   Ann Anat 189 (3), 223-228 (2007)
   PUBMED   17534028
  REMARK    GeneRIF: Part of a family of RNa-binding proteins found in sensory
            neurons.
REFERENCE   3  (bases 1 to 1597)
  AUTHORS   Inoue M, Muto Y, Sakamoto H and Yokoyama S.
  TITLE     NMR studies on functional structures of the AU-rich element-binding
            domains of Hu antigen C
  JOURNAL   Nucleic Acids Res 28 (8), 1743-1750 (2000)
   PUBMED   10734193
REFERENCE   4  (bases 1 to 1597)
  AUTHORS   King PH.
  TITLE     RNA-binding analyses of HuC and HuD with the VEGF and c-myc
            3'-untranslated regions using a novel ELISA-based assay
  JOURNAL   Nucleic Acids Res 28 (7), E20 (2000)
   PUBMED   10710437
REFERENCE   5  (bases 1 to 1597)
  AUTHORS   Abe R, Sakashita E, Yamamoto K and Sakamoto H.
  TITLE     Two different RNA binding activities for the AU-rich element and
            the poly(A) sequence of the mouse neuronal protein mHuC
  JOURNAL   Nucleic Acids Res 24 (24), 4895-4901 (1996)
   PUBMED   9016658
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000190.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by NM_172324.3.
            
            On Nov 27, 2020 this sequence version replaced NM_172324.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB097198.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN14984041 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                JACYVU010000190.1  5387146-5387193     c
            49-268              JACYVU010000190.1  5372598-5372817     c
            269-372             JACYVU010000190.1  5372287-5372390     c
            373-526             JACYVU010000190.1  5361720-5361873     c
            527-752             JACYVU010000190.1  5361396-5361621     c
            753-791             JACYVU010000190.1  5360132-5360170     c
            792-1597            JACYVU010000190.1  5354433-5355238     c
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..1597
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /note="ELAV like RNA binding protein 3"
                     /db_xref="GeneID:282824"
                     /db_xref="RGD:628892"
     exon            1..48
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1143
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /note="ELAV (embryonic lethal, abnormal vision,
                     Drosophila)-like 3 (Hu antigen C); ELAV like
                     neuron-specific RNA binding protein 3"
                     /codon_start=1
                     /product="ELAV-like protein 3"
                     /protein_id="NP_758827.1"
                     /db_xref="GeneID:282824"
                     /db_xref="RGD:628892"
                     /translation="MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVN
                     YLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNG
                     LKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQ
                     ATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHL
                     YQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLS
                     GGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTN
                     YDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA"
     exon            49..268
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /inference="alignment:Splign:2.1.0"
     exon            269..372
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /inference="alignment:Splign:2.1.0"
     exon            373..526
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /inference="alignment:Splign:2.1.0"
     exon            527..752
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /inference="alignment:Splign:2.1.0"
     exon            753..791
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /inference="alignment:Splign:2.1.0"
     exon            792..1597
                     /gene="Elavl3"
                     /gene_synonym="Huc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgccctcga tacggaccgc gcccgccggg cacacaagaa tggtcactca gatactgggg
       61 gccatggagt ctcaggttgg gggggggccg gccggcccgg ccctgcccaa cgggccactc
      121 cttgggacaa acggagccac tgacgacagc aagaccaacc tcatcgtcaa ctacctaccc
      181 cagaacatga cgcaggacga gttcaagagt ctcttcggca gcattgggga cattgaatcc
      241 tgcaagttgg ttcgggataa gatcacagga cagagcctag gctatgggtt tgtgaactac
      301 tctgacccca atgatgcaga caaagccatc aacactctca atggcctcaa actgcagacc
      361 aagaccatca aggtgtccta tgcacgtccc agttctgcct ctatccggga tgccaacctg
      421 tacgtcagtg gcctccccaa gaccatgagc cagaaggaga tggagcagct cttctcccag
      481 tacggccgga tcatcacttc cagaatcctg ctggaccagg ccacaggtgt ctctcggggt
      541 gtgggattca tccgctttga caagaggatc gaggcagaag aggctatcaa aggactgaat
      601 gggcagaagc cactgggtgc tgctgagcct atcacggtca agtttgcaaa caacccaagt
      661 cagaagacag ggcaggccct gctcacccac ctgtaccagt cctctgccag gcgctacgct
      721 ggtcccctgc atcatcagac acagcgcttc cggctggaca atttgctcaa catggcctac
      781 ggagtcaaga gtcccctgtc gctcatcgcc aggttctccc caatcgccat cgatggcatg
      841 agtggcctgg caggcgttgg cttgtctgga ggcgctgcag gcgctggctg gtgcatcttc
      901 gtgtacaacc tgtccccaga agcggatgag agtgtgctgt ggcagctttt cggacccttt
      961 ggggcagtca ccaatgtcaa ggtcatccga gatttcacca ccaacaagtg caagggtttc
     1021 ggcttcgtca ccatgaccaa ctacgatgag gccgccatgg ccatcgccag cctcaatggc
     1081 tatcgcctgg gcgagcgtgt gctgcaggtg tccttcaaga ccagcaagca gcacaaggcc
     1141 tgagcattac cgccctccct ccccgggcag cagagagaga gagagagaga gagagagaga
     1201 gagagagaga gagagagaga agagtgtgcg caaccgcaag agcaggcaga cccacacacc
     1261 tgcaaacaca ccacagggtg agcatccgga cggggagggt ctgcagggaa ttgagggaag
     1321 ggtgtcccca ccctgttctc cttgctttcc ccaccccagg ctggggcttg ttcactctct
     1381 cgtcttggtt tggttcatgg tgatggcttt tgtttctttt ttcggctaaa aacaaaaaga
     1441 agaaagcaga gaggagaccc ccatcccacc tcaccctcac caccctgcac aggatggctt
     1501 aggggacaca atggtgccct actcaggcct cccttgccca ggcctgtcct ataccgagag
     1561 aaaggggagg gaacaggttt aaaaatcccc aaaacag
//
