LOCUS       XM_056985272            6459 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus endosome-lysosome associated apoptosis
            and autophagy regulator 1 (Elapor1), transcript variant X1, mRNA.
ACCESSION   XM_056985272
VERSION     XM_056985272.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 3, 2024 this sequence was replaced by
            NM_001427831.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6459
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6459
                     /gene="Elapor1"
                     /note="endosome-lysosome associated apoptosis and
                     autophagy regulator 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 42 ESTs, 14
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 41 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:362019"
                     /db_xref="RGD:1310209"
     CDS             748..3789
                     /gene="Elapor1"
                     /codon_start=1
                     /product="endosome/lysosome-associated apoptosis and
                     autophagy regulator 1 isoform X1"
                     /protein_id="XP_056841252.1"
                     /db_xref="GeneID:362019"
                     /db_xref="RGD:1310209"
                     /translation="MAEPGHNPQPSAREGGRTERRTSRLLWLLLWAGTTFQVTLGTGP
                     ELHACKESEYHFEYTACDSTGSRWRVAVPHSPGLCTSLPDPVKGTECSFSCNAGEFLD
                     MKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSANLEVDDSISESTENCTSSKWV
                     PRGDYIASNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDS
                     RWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWSKVSKPVLVRNIAITGVAYTSECF
                     PCKPGTYAAKQGSPFCKLCPANSYSNKGETSCHPCDADKYSEKGSSTCKVRPACTDKD
                     YFYTHTACDAQGETQLMYKWAMPKICGEDLEGAVKLPASGVKTRCPPCNPGFFKTNNS
                     TCEPCPYGSYSNGSGCTHCPAGTEPAVGFEYKWWNTLPSNMETTVLSGINFEYKGLTG
                     WEVAGDHIYTAVGASDNDFMILTLVVPGFRPPQSVMADTENKEVARITFVFETICSVN
                     CELYFMVGMNSRTNTPVETWKGTKGKQSYTYTIEENATVSFTWAFQRTTLHETGRKYT
                     NDVAKIYSINVTNVMGGVASYCRPCALEASDLGSSCTSCPAGHYINRDSGTCHLCPSN
                     TILKAHQPYGAQACVPCGPGTKNNKVHSLCYNDCTFSRNTPSRTFNYNFSALAGTVSL
                     AGAPSFTSKGLKYFHHFTLSLCGNQGKKMSVCTDNVTDLRIPEGEAGFSKSVTAYVCQ
                     VVIIPSEVMGYKAGVSSQPVSLADRLVGVSIDMALEGIVSPAELFHPETPGIPDVVFF
                     FRSNDVTQSCSSGRSTTIRLRCNPMKPTPGTLRLPSMCSDGTCDGCNFHFLWESVAAC
                     PLCSASDYHTFVSSCVAGIQKTTYMWREPKLCSGGISLPEQRVTICKTIDFWLKVGIS
                     AGTCTAILLTVLTCYFWKKNQKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDD
                     LIFTSKKSLFGKIKSFTSKRTPDGFDSVPLKTSSGGPDMDL"
ORIGIN      
        1 tcaaatcaat gagagtaaga gaatgtcaaa aaaaaaaaaa atcaaagatc tcacgtgtcc
       61 tagttggaaa attgtcgatt aggtcaccct cgctgtttaa ctatgcagac gtcagggttg
      121 ctcaccgaga cggctgtaaa aacgtgaatg gacttggcgg ggtggaagga tggaactaaa
      181 ttttgcagtt actgctgggg ccactctagg agacgatccc tggaagatga cgaagacctc
      241 tgtcttcccc caatcgtttt ataagccatg tttacaaaat aagagaagct tagaaatagc
      301 ctcccggccc ggaagagtaa taggtgcgaa atgagccgct gcagatgttt tgaaggttct
      361 tctactgcgt gctttacgta acgtaagcct attcggttac ttgcaaaccc tggcgcgtgc
      421 actcccatgc cgcgcgccag cggtggcggc tgccatggag accggcaggt gagcggcaca
      481 ggcgcgcgtg gtccttgccc cacccgcgct gagcgaagag gatgcggttg tcaaggcgac
      541 atggatagga ggaggagagg accgagggag gagggatggg cggccttggc gtagccgcag
      601 ggaggtgact gaagcgagtc cagccccttg catcctcctc tgtgtacctc cctcctcttt
      661 ttcttttttt tttttttcct ccttctgcca gcataagcag ctaccgcagc acctgagccg
      721 ctactgccgc tggctcagga cagcgctatg gctgagcctg gtcacaaccc ccaaccttct
      781 gccagagaag gcggaagaac tgaaaggcgc acatcccggc ttctgtggct gttgctttgg
      841 gctgggacca ccttccaggt gaccctggga accggacccg agcttcacgc ctgcaaagag
      901 tcagagtacc attttgaata cacagcgtgt gacagcacag gttccaggtg gagggtcgcc
      961 gtgccacaca gcccgggctt gtgcaccagc ctcccagacc ccgtcaaggg caccgagtgc
     1021 tctttctctt gcaatgccgg ggaatttctg gacatgaagg accagtcctg caagccgtgt
     1081 gcggagggcc gctactccct cggcactggc atccgatttg acgagtggga tgagctgcct
     1141 cacggctttg ccagcctctc ggccaacttg gaagtcgatg acagcatctc agagtccacc
     1201 gagaactgca cttcgtccaa gtgggttccg aggggagact acatcgcctc caacacggat
     1261 gaatgcacag ccacactgat gtatgccgtc aacctaaagc agtccggcac agttaacttt
     1321 gagtactact acccggactc cagcatcatc tttgagtttt tcgtccagaa tgaccagtgc
     1381 cagcccaatg ctgatgactc cagatggatg aaaactacag agaaaggatg ggaattccac
     1441 agtgttgagc taaacagagg caataatgtc ctctattgga gaaccacggc gttctcagtg
     1501 tggtccaaag tgtccaaacc cgtgcttgtt agaaacatcg ccataacagg ggtagcttat
     1561 acctctgagt gtttcccctg caagcctggc acctatgccg ccaagcaggg ctcccctttc
     1621 tgcaagcttt gtccagccaa ctcttactca aacaaaggag aaacttcatg tcatccgtgt
     1681 gatgctgaca aatactcaga gaaaggatct tccacctgca aagtgcgccc ggcctgcaca
     1741 gacaaggatt acttctacac tcacacagcc tgcgacgctc agggagagac acagctcatg
     1801 tacaaatggg ccatgccaaa aatctgtggc gaggacctgg agggagccgt aaagcttccc
     1861 gcctccggcg tgaagacccg ctgccctccc tgtaacccag gcttcttcaa gaccaacaac
     1921 agcacctgtg aaccgtgccc atacggctcg tactccaatg gttccggttg tacccactgc
     1981 ccagcaggaa ctgagcctgc cgtgggattt gagtataaat ggtggaacac attgccctcc
     2041 aacatggaaa ctactgttct cagtgggatc aactttgaat acaagggctt gacaggctgg
     2101 gaggtggctg gtgaccacat ttatacggct gttggagcct cagacaatga cttcatgatt
     2161 ctcactctgg ttgtgccagg atttagacct ccccagtcag tgatggcaga cacagagaac
     2221 aaagaggtgg ccaggatcac atttgtcttc gagaccatct gctctgtgaa ctgtgagctg
     2281 tacttcatgg tgggcatgaa ttccaggacc aatactccag tggagacgtg gaaaggcacc
     2341 aaaggcaaac agtcctatac ctacaccatc gaggaaaatg ctactgtgag cttcacatgg
     2401 gccttccaga ggaccaccct tcacgaaaca ggcagaaagt atactaatga tgtcgccaag
     2461 atctactcga tcaatgtcac caacgtcatg gggggtgtgg cctcctactg ccgtccctgt
     2521 gccctagaag cctctgattt gggctcctcc tgcacctctt gtcctgctgg ccattatatc
     2581 aaccgggatt ctgggacctg ccacctctgt ccctctaaca ccatcctgaa agctcaccag
     2641 ccttatggtg cacaggcctg tgtgccctgt ggtccaggga ccaagaacaa caaggtccac
     2701 tctctctgct acaatgactg caccttctcc cggaacactc ccagcaggac tttcaactac
     2761 aacttctcag ctctggcagg cactgtctct ctggcaggcg cacccagctt cacttcaaag
     2821 gggttgaagt attttcatca tttcacgctg agtctctgtg gaaaccaggg aaaaaagatg
     2881 tctgtatgca cagacaatgt cactgacctc cggatccctg agggcgaggc cggtttctct
     2941 aagtccgtca cagcctatgt ctgccaggtg gtcatcatcc cctctgaggt gatgggctac
     3001 aaggctgggg tatcctcaca gccagtcagc cttgctgaca gacttgttgg agtgtcaata
     3061 gacatggctt tggaaggaat cgtctcccca gctgaacttt ttcacccaga gaccccaggg
     3121 atcccggacg tagtcttctt tttcagatcc aatgatgtga ctcagtcctg cagctctgga
     3181 agatcaacca ccattcgtct cagatgcaac cccatgaaac ctacacctgg tacccttcgg
     3241 ctacccagca tgtgctctga tgggacctgt gatggctgta acttccactt cctgtgggag
     3301 agtgtggctg cttgtccact ctgctcggcc tctgactacc acacttttgt cagcagctgt
     3361 gtggctggga tccagaagac tacttacatg tggcgagaac caaagttgtg ttctgggggc
     3421 atttccctgc ctgagcagag agtcaccatc tgcaaaacga tcgatttctg gttaaaagtg
     3481 ggcatctcgg ctggcacctg cactgccatc ctgctcactg tcctgacctg ctacttttgg
     3541 aagaagaatc aaaaattaga atacaaatac tccaagctgg taatgaatgc tactcttaaa
     3601 gactgcgacc tgccagcagc agacagctgt gccatcatgg aaggggagga tgtggaagac
     3661 gacctcatct ttaccagcaa gaagtccctc ttcgggaaga tcaaatcctt tacctccaag
     3721 aggactcctg atggatttga ctcggtgcca ctgaagacat cttcaggagg cccagacatg
     3781 gacctgtgag aggtgttcat cctgcctcgc ctgcctcctc acctgggcat attaccctgc
     3841 aggcctgtgg caatttaggt gccagcatcc tgcgctcccc actgctggga atctcttcat
     3901 tgtggcctta tcagaagttt ggatttcaga cccttctttt ttatagagta cccaaacttt
     3961 cttctctgct tgcctcaaac ctaccaaata tacccacact tcgtgtattg tttccttgct
     4021 tacatcttgt tttctaagat agcctaccca cggggccaga ccctcatctg cccagaattc
     4081 ttagagtctt tgagtgaaag caattatttt ttaagtgtga aattgacttc tggccttctg
     4141 tttgaggaca ggagcagctg ggaggttttc tggtccaata caggctttca actcttgatg
     4201 tctttagaag ggaggccgtg gcctgagtga ggggcagtct tcctggcaac ctccatttat
     4261 ttctcctggg taatgagttt gagtagggag cagtggccaa tctgagggca aggtgggtga
     4321 agcctgtgta agaagagact ggaaaaacac aaagaaaggc aaacaagaaa ggggggttca
     4381 ttctgtttta taaccaggta cctaatttcc ttctctttaa atgataaata ttctcactaa
     4441 aggcaaagga agttatttat aaagaacttg cctaaagtcc taatagagct attcgccatg
     4501 attgttttag tcaaatctct cttccatctc tttataacat tagaaagaac caggtaagtc
     4561 tagctataat cctccactgg ctttgctgga agggagtaaa cacttgccag tgaggaacac
     4621 tcccatctgt gagtgcctca gttctagagt cctagagcat tatgggatgg agcatcttat
     4681 ttagaaagaa ctcagggggc tagggattta atggggtaat attaggatcc agcccactgt
     4741 ggcatggacc agctatggtc atgatatcgg tttctgactt tatcttactt gctacatcac
     4801 aaaattataa acttctagat tgaccagaag gagacgaatg tcaggcagat acaaactaat
     4861 cttcagggaa gaaaagtaga gatgtctcac aaggcctgca cccagctggg gcatttgtta
     4921 cccctaagcc tctgccctgg ctctggccta ttctcatttc atttgtgcac taaacatcta
     4981 aaagactcct ggccctcatt tctgataaca ctcctctgaa aggtagatta ggtacgaact
     5041 cacaagtaga gtgggattcc tcttcccatt tctcttttac tccagatcca attggtgaaa
     5101 aacccagaat agaaacacaa gagaacaatt tccagttaac gttttttccc ctactactgg
     5161 gaatggaacc tctttcattc catgccagaa tggccatctc ttggtcaatc ctgagttacc
     5221 cagggtcttc acctgtgccc tttccccagg gacaggtggt tggtatagga cagagaggca
     5281 tttctgagtg gtttgtcagc cacgaaatga cttgcccatc tggtgatggt atatctaaga
     5341 gtcagaaaga agtgaagcta tgccatgact tttgaccatg aaaggcatca gtaatagcta
     5401 gccaaaccta gaagctcttc tttgggcttc caagctgtcc ctcattttgt ggctctcaga
     5461 accttgacta tactggaata ttcttgcgta gatatgcaca cccaggccat gagctcgcag
     5521 ccagtctcct tcagcttcct gggtgcctgc ttcccgtgga gtaactgctt tctgtgaaga
     5581 agaccacagg agatacttag actgttctgg agctatgggg aaatgttcat ctctttggac
     5641 ttcttcagtc tgacatcgtg gaattgagtg cccctcctct ctagcatcct caaacagcac
     5701 tgattcaatg aaagaacctt tttggatctc taccctactc tttactggga tgtttccaaa
     5761 agggaagagg gtcacctgtt gcttctttag catctcaaca acttcagata atttcaggag
     5821 ctctactgac agataattca catactgcac aagtcaccct ttcagagcat acagttctgt
     5881 gactttgggt atatacattt tagttttctg tgctgaagat gaaacctggt tttctcacat
     5941 gctaagcaaa gtgttctacc actgagctac atcattgacc atgaatatat agttcagaac
     6001 acacacacta ggtctgccag ggagaacagc ttcagtcttt gagccaggac tattgtagct
     6061 tacacaaact tcagggccag agagttggct caggagatca tgtttaatct ccatatggat
     6121 gtatagagtc ctagaataca taattccacc ctgtagttag ctgtcacctg tttttggctg
     6181 ggaatacata tgaagattat ggtatatcca aggcccaggg gatttcttat gccatcaaac
     6241 cttttttttt tgttggtcca actatattaa agataaaact gactatattt atacaacaga
     6301 agctttgtaa aagatttttc agctttgtgg aaatcacatt tatgtctcat caagacgggt
     6361 tggattccct ttttattctg tatttcaagc atttagtttg ttagggatgg gtgttgcatg
     6421 tctttttttc ccccccgaaa taaaaaccat atcttttga
//
