LOCUS       NM_001100697            4871 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 5A2
            (Eif5a2), mRNA.
ACCESSION   NM_001100697 XM_001063995 XM_226974
VERSION     NM_001100697.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4871)
  AUTHORS   Chen,M., Huang,J.D., Deng,H.K., Dong,S., Deng,W., Tsang,S.L.,
            Huen,M.S., Chen,L., Zan,T., Zhu,G.X. and Guan,X.Y.
  TITLE     Overexpression of eIF-5A2 in mice causes accelerated organismal
            aging by increasing chromosome instability
  JOURNAL   BMC Cancer 11, 199 (2011)
   PUBMED   21612665
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4871)
  AUTHORS   Clement,P.M., Henderson,C.A., Jenkins,Z.A., Smit-McBride,Z.,
            Wolff,E.C., Hershey,J.W., Park,M.H. and Johansson,H.E.
  TITLE     Identification and characterization of eukaryotic initiation factor
            5A-2
  JOURNAL   Eur J Biochem 270 (21), 4254-4263 (2003)
   PUBMED   14622290
REFERENCE   3  (bases 1 to 4871)
  AUTHORS   Jenkins,Z.A., Haag,P.G. and Johansson,H.E.
  TITLE     Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved
            vertebrate variant of eukaryotic translation initiation factor 5A
            with tissue-specific expression
  JOURNAL   Genomics 71 (1), 101-109 (2001)
   PUBMED   11161802
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001100697.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2429754.1,
                                           SRR26643291.6056.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                JAXUCZ010000002.1  113657834-113657916
            84-284              JAXUCZ010000002.1  113658515-113658715
            285-389             JAXUCZ010000002.1  113659220-113659324
            390-521             JAXUCZ010000002.1  113669566-113669697
            522-4871            JAXUCZ010000002.1  113670249-113674598
FEATURES             Location/Qualifiers
     source          1..4871
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q24"
     gene            1..4871
                     /gene="Eif5a2"
                     /gene_synonym="eIF5AII"
                     /note="eukaryotic translation initiation factor 5A2"
                     /db_xref="GeneID:310261"
                     /db_xref="RGD:1306196"
     exon            1..83
                     /gene="Eif5a2"
                     /gene_synonym="eIF5AII"
                     /inference="alignment:Splign:2.1.0"
     exon            84..284
                     /gene="Eif5a2"
                     /gene_synonym="eIF5AII"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..581
                     /gene="Eif5a2"
                     /gene_synonym="eIF5AII"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 5A-2"
                     /protein_id="NP_001094167.1"
                     /db_xref="GeneID:310261"
                     /db_xref="RGD:1306196"
                     /translation="MADEIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMS
                     TSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDGYLSLL
                     TETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK"
     exon            285..389
                     /gene="Eif5a2"
                     /gene_synonym="eIF5AII"
                     /inference="alignment:Splign:2.1.0"
     exon            390..521
                     /gene="Eif5a2"
                     /gene_synonym="eIF5AII"
                     /inference="alignment:Splign:2.1.0"
     exon            522..4871
                     /gene="Eif5a2"
                     /gene_synonym="eIF5AII"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctggaccag ccgcggccgc cagcgccgcc gcagccgcag ggaccgggcg gacgcagcaa
       61 aggcttgcgg tgcgggccgg aagttccctc agaaaaacca cacatctccc cagcccacca
      121 tggcagacga aattgatttc actactggag atgcaggggc ttccagcact tatcctatgc
      181 agtgctcagc cctgcgcaaa aacggcttcg tggtgctcaa agggcgtcca tgcaaaatcg
      241 tggagatgtc aacttccaag actgggaagc atggtcatgc caaggtacac cttgttggaa
      301 ttgacatttt cactggcaaa aaatatgaag atatttgtcc ttccactcac aacatggatg
      361 ttccaaacat taagagaaat gattatcaac tcatatgcat tcaggatggt tacctttccc
      421 tgctgacaga aactggcgaa gtccgtgagg atctcaagct gccagaaggt gaactgggca
      481 aagaaatcga agggaagtac aatgcaggtg aagatgtgca ggtgtccgtc atgtgcgcca
      541 tgagtgaaga atacgctgta gccataaagc cctgcaaata ggcagggccc tgagcacaag
      601 catgtccact gggtctggat ctagttgtcc caaagctatg gccttcataa gcaacctcat
      661 gtttgttttt gttatgtttt tattgtttta aaaatgtgct ggcttaggtt tgcaggcagt
      721 tagtaagtct aaatgaatat accaagatgt ataattttat aagtatcttt cctataacac
      781 tcctgtggtt ttcatcatgt gaccataaga cacaaataca acagcttcag taatgtcact
      841 tgtctgagca aatcactcct gaacttaagt ggttaacaaa ccagggttta aagtcagcaa
      901 tgtagcagct agtggaatgg aagtgccatg cttttcagcc aaattgcttt gtgctgattt
      961 cagacttaat atccagagtc atagattata aaatggtctg tgtgacaaac atacatcttg
     1021 aaacaactct ttttatcatt ctcttggtgg ccaggtgccc catgtattcc cttcatcatg
     1081 tttttctgtg ccaggttggt gatgacagac atacagggaa catggaggga acagaactgc
     1141 tgagtaagtc tgagcaagtt caccaagtgg agaagaagac cagggtagag gcaaagcagg
     1201 ggttaacgct gtagctttta ttgaagacct tttaatcagc acacaaagtg aaggagctct
     1261 ggttgtattt ttgcttttgg ctatgtccca gcctctgcct cagcacagca gtgacctttg
     1321 cagagacact cactacttcc agccataatg cctaagtggt catggtgttg gtaacccagc
     1381 ccttccagca attttttaag taattcgttt ttaacattag actgaaatta ggaattttta
     1441 agttgatttg gaattcctga ctttgatttg ttaaatatgt gcacacttct ctaaagtgat
     1501 aggtgtgaac catggaagaa agattacctt atgtgaaaac tagcttaagt gtgtgcatac
     1561 cttatatctc ttgggacttg gttctttact gatgtgaaat ataagtagga aagggttctg
     1621 tgacctggat tgttttgctg cgttgtaggt aatgcccctc cattctgttt agacttttgg
     1681 atcgtgtgta aattgtgtct aaaattgtag acatagttgt aggcttgtga ggaacagaca
     1741 aaatcacaat catggcattg gagcacaact tagagcaaaa gtcctctgaa caacacctca
     1801 aatctctgag gctggctctc ctctcaggtc cctttctcat gtctggactc tttgttccca
     1861 tctagaaaaa atgtgtgaca aggtaactca tctaatgagc aacttgaaat agcattacaa
     1921 atggaagatc ccaagatttt agttgcttaa tttgtatgca gttttaaatc ttgtcttggc
     1981 ctccacaaac caatccagag aagaagcaag atacagtacg agacgtgcca ggaagaggtg
     2041 tctaaagcac aagaacattg aagttgccgc cagttgactt tagtgtgacc ctttagcttt
     2101 tgcacgtgca aagcacaatt aggaattagg ctgaattctt cccaggtatc tgctctgtgc
     2161 tgctttagat ttctgctgtt aggatgtgtt cctggcagtg cctcttgacg gggtacgtag
     2221 gaattgcaga aagttatttc tctctgctct tctctggtca ttggctggct agtaagtagc
     2281 cacactggtg ttttgatttc atattctcca ggagtagcat gccctttttc ttcctaactt
     2341 atcaaactcc acatgcacct ctatttttca ttgtagtata catataaatt agagcaatgt
     2401 acctctagct ccatgccttg aatggcaaaa gctacttagg cctaagtatt taattttaaa
     2461 tactatataa gtgtacatac tccaacatgt aactatagat tttaaagata caggactgtt
     2521 tattttcaca taagtcagta gatgtttctc ttaaagcata atatttcatt tagtaaagct
     2581 ttataaatta tattaaaggg aagcaggaaa catgtatttt ttaacagaaa ttgcttcttt
     2641 tgacatcaga aaaatgctaa gagttgattc caagtatttg ttgtactcgt agcagatctc
     2701 cagtttccca ggcaccatgt tgagaacgga gttcattcag acgtcaccac atgtctgtgt
     2761 ctgtacacat gtgtttcttt ctttgccatg tagacagtat taacaggttg agcatttttg
     2821 ttctagaata acagcttaat ttccaccatg aagactttgc cacactggta caattgtgtg
     2881 ccctctgaca taggtcagac ctttttggct ttgacttggt ctttgcatcc ttcatgcctc
     2941 ctgggggctg ccagtctctt gaagtggtaa ccaagctctt gactctgttc cccttcatag
     3001 tacagatgtc tataccagtg cttgatatca gtgaccaaaa ctctcgcagc cagacgtgat
     3061 atctttaaga acacgctgca tgcgatgttt agaaaatctg gggatacatg cttttcacta
     3121 gtgcacagtg tgtgtgtata aatacacata gctttgttca tttctcaaag tccttccaac
     3181 tattaaatgt actgtagtct ggtagtgcct caaatgttgg tttgattttt gtgttttttt
     3241 aatttataag ttttccagaa tttgttcttg acttttaagg ctactcgact agattgtttc
     3301 tagttgagct gaaattcaaa tgcattgttc tcagggctgt ttgtgctagg agctgaagtg
     3361 tcattattta aagatagctg cctacaaata tattgcaagt ttttcccacg tcatgatact
     3421 gtaatacata caaataaaaa ttcttagtaa aacatttaag ctgtctggta agcatttttt
     3481 ttaaatgtct gggagcatta gtagcagctg tactggaatc ttgctgtagc ttttactcta
     3541 gagtagaatc ccaggggtct ttccactgga gccctgttct tagtgatgta tctgagcgct
     3601 tctggcatgg acgccaaaga gagctttgga cctagacatt gaatctgtgt tctcagacac
     3661 attcaagagc agacaggaaa ttccatactg ttttgggtat ctgaaaatgt ttacatgctg
     3721 aatccacact tgctatgaga aaatatggat gtctagtata agatcaaagc tatcaaggcg
     3781 tatttccaca gacagtatac tatactgaca tgaactttta aatcttctaa tatttaagta
     3841 gaatatttca tagttcttaa gccctttttc tgttaacatt tcgatgaata agaggcaaca
     3901 aagacttttt ttaaactatg gtagacaaat cttaaaattg aatctattaa cttaaatctg
     3961 tgaaatgcat tctctgaatt ggacaaacaa cattattatt tgattgtaga gggaacattg
     4021 ggtcttagct tacggagcac agatgttctg tggaaacagg gtttgaagtc actatgtaat
     4081 ttaatttttc cattaaccca aacactgact taactaccaa gtgagatcac atacctgaaa
     4141 agagctgtag atatctaata aatatgtttt cttcatgtgg aggacgcatt gtagggcagt
     4201 gtgcaaaagg ccatcacctg ctataaacat aatcattgcc aaacttttcc atcactgctc
     4261 ttcacactta aaccaggcct gggcctattt atagtaacaa gggagattct tttctgtaga
     4321 tgaagttttt agaaaccatt tccagatgct ggcgggattt cgtcatctta gtttgaaact
     4381 gtacttttaa aaacactgga tacagaacta ttgagcaatg tctgaagagc ctctgagaga
     4441 tggtggctgt gctctcttaa gctgattctt tatcgtggtt attctactac aagtaagcgg
     4501 tcatcgttat tacaaggact gcttcacatt actatctcta aaccacgata aacaaatgac
     4561 tgtttcccta ttctcatgta ctcttccccc tccctagagg aaaacagatc aaaggacatt
     4621 gtctaatcca ttggcacttt gttaggatta ttttttgtct taaatatagg atacttattg
     4681 aatttacttg caaatgtttt gttaaaactt taaaattata ataagttctg aatattataa
     4741 ttgtacgttt tacatttcag aagtaacttt gaatgttaaa tctccagcta tactaatttg
     4801 ttaccttaaa atatgtctgt taacttcatg ttatattaaa tgaaaataaa cttaacagtg
     4861 cacaattctt a
//
