LOCUS       NM_001402208            3228 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 4E
            family member 2 (Eif4e2), transcript variant 5, mRNA.
ACCESSION   NM_001402208
VERSION     NM_001402208.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3228)
  AUTHORS   Morita,M., Ler,L.W., Fabian,M.R., Siddiqui,N., Mullin,M.,
            Henderson,V.C., Alain,T., Fonseca,B.D., Karashchuk,G.,
            Bennett,C.F., Kabuta,T., Higashi,S., Larsson,O., Topisirovic,I.,
            Smith,R.J., Gingras,A.C. and Sonenberg,N.
  TITLE     A novel 4EHP-GIGYF2 translational repressor complex is essential
            for mammalian development
  JOURNAL   Mol Cell Biol 32 (17), 3585-3593 (2012)
   PUBMED   22751931
REFERENCE   2  (bases 1 to 3228)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 3228)
  AUTHORS   Rosettani,P., Knapp,S., Vismara,M.G., Rusconi,L. and Cameron,A.D.
  TITLE     Structures of the human eIF4E homologous protein, h4EHP, in its
            m7GTP-bound and unliganded forms
  JOURNAL   J Mol Biol 368 (3), 691-705 (2007)
   PUBMED   17368478
REFERENCE   4  (bases 1 to 3228)
  AUTHORS   Tan,N.G., Ardley,H.C., Scott,G.B., Rose,S.A., Markham,A.F. and
            Robinson,P.A.
  TITLE     Human homologue of ariadne promotes the ubiquitylation of
            translation initiation factor 4E homologous protein, 4EHP
  JOURNAL   FEBS Lett 554 (3), 501-504 (2003)
   PUBMED   14623119
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.40396.1,
                                           SRR26643284.12600.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               JAXUCZ010000009.1  95334386-95334557
            173-287             JAXUCZ010000009.1  95340226-95340340
            288-422             JAXUCZ010000009.1  95342394-95342528
            423-527             JAXUCZ010000009.1  95346559-95346663
            528-680             JAXUCZ010000009.1  95348205-95348357
            681-817             JAXUCZ010000009.1  95348450-95348586
            818-3228            JAXUCZ010000009.1  95359956-95362366
FEATURES             Location/Qualifiers
     source          1..3228
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q35"
     gene            1..3228
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /note="eukaryotic translation initiation factor 4E family
                     member 2"
                     /db_xref="GeneID:363275"
                     /db_xref="RGD:1307790"
     exon            1..172
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..857
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /note="isoform 5 is encoded by transcript variant 5;
                     eukaryotic translation initiation factor 4E like 3;
                     eukaryotic translation initiation factor 4E type 2;
                     eukaryotic translation initiation factor 4E member 2"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 4E type
                     2 isoform 5"
                     /protein_id="NP_001389137.1"
                     /db_xref="GeneID:363275"
                     /db_xref="RGD:1307790"
                     /translation="MSLKDDDSGDHDQNEENSTQKDGEKEKTDRDKSQSGGKRKAVVP
                     GPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWKFYSHMVRPGDL
                     TGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEE
                     ICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKD
                     NSSFRNTKITL"
     exon            173..287
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /inference="alignment:Splign:2.1.0"
     exon            288..422
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /inference="alignment:Splign:2.1.0"
     exon            423..527
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /inference="alignment:Splign:2.1.0"
     exon            528..680
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /inference="alignment:Splign:2.1.0"
     exon            681..817
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /inference="alignment:Splign:2.1.0"
     exon            818..3228
                     /gene="Eif4e2"
                     /gene_synonym="Eif4el3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcgcttcgg gtgtttccgc agccttgctg ccttctctct gaaagcggct tccctcccgc
       61 actcgctctg cgtcctggga aggtcacctc tcccttccga acctcggttt tgtcttctgc
      121 aagcggggac ggtaacagag cccgtgtcct agagttgggc agctgcgatg agcttaaaag
      181 atgatgacag tggagaccat gatcagaatg aagaaaacag cacacagaaa gatggtgaga
      241 aggaaaaaac agaccgagat aagagccaga gtggtggcaa gaggaaggct gttgtccctg
      301 gaccagcaga acatcccctg cagtacaact acaccttttg gtactctagg agaacccctg
      361 gccgtcccac cagttcacag agctatgagc agaacatcaa gcagattggc acctttgcct
      421 ctgtggaaca gttctggaag ttttacagcc acatggtccg tcccggggac ctgacaggcc
      481 acagtgactt tcatctcttt aaagaaggaa tcaaacctat gtgggaggat gatgcaaata
      541 aaaatggggg caagtggatc attcgactcc ggaagggctt agcttcccgc tgctgggaga
      601 atctcatcct ggccatgctc ggggaacagt tcatggttgg ggaggagatc tgcggggctg
      661 tggtctctgt ccgcttccag gaggacatta tttctatatg gaataagact gccagcgacc
      721 aagcaaccac agcccgaatc cgggacactc ttcggcgcgt gcttaaccta cctcccaaca
      781 ccattatgga atacaaaact cacaccgaca gcatcaagga caattcaagc tttcgaaata
      841 caaaaatcac attgtgaaag cgcacaagtt ggcagtattc tttttctgtt tgtgtgtttg
      901 tctgacttgg atgcgaggct caggcagttc tctgtctgtt cactgaaggg gtgtacctaa
      961 accatgtgct ccccttctgc actcgttcct ggaagaagga cagactctgc tagacacctt
     1021 ccagcaatgc tgaccgtata cagcgggaag aatgggaaaa tgtgactgtg taacagacaa
     1081 acacttttca gtggggttct gtgtggagtg cagctgtctt cttgctgtgt actatccaga
     1141 tgcctcttgg catcctgctg tactctcctg ctgtgcaaag gacttgatgg ccgaggacat
     1201 gtgtgtgccc ggtgtgggtc tgagctgagc gttatcagta ttatgaatgc ttgcacatcc
     1261 aggaacagcc tctgcttaga gttgaagaga actaaatgcc tcttctagct ctactgttaa
     1321 gttattgtgt gttcctcttc cctaagccca ccactttgaa catgtgttaa gatatgatga
     1381 cagctaggat aatgtatcct ttgcgcctta cacctccaat gggactcttc ttcttaggca
     1441 ctgcagcact tcaatcgtga ttctgggcag cacaggtttt actgaggaaa cctaaggcat
     1501 ctgccctgta agacaagctg gagaagaatg cagttcagtc agaagccaga ttatagtgca
     1561 ggtcccacac atggggttgg ggctgaagcc agtgactgaa accagcctcc cctgtgagca
     1621 ggacttgtgt gctgagcatg ctctgtgggg gttgcatgtc tgccatggag gaggaagcca
     1681 cagctggtag tgccacatta aaaccgtgta gctcccacag tgctggaatg ggtgactgaa
     1741 gaaatggcag ccttgctgga tgctttcatt tgatggctgt gtctgtcagc tgtgattgga
     1801 aaagactttg gtccttgaca cctggatgta atcaactcgt ccagacccct cgatgcccag
     1861 aaggctccta caggcatgtc ttcagcaaag aagctgactt tgggagcctg aggccagagg
     1921 tcgaaagagt acccaagatc aaggaagaaa tgggcagctg cagctgcttc aagtgctctg
     1981 tactgggctc ttgtgagcca agatggcagt accttaaatt aaggcctctt tttaaagcct
     2041 atccctgagg cctgggcggg gctcctcggc cacaggtctc aggaattctg aaggtaacag
     2101 catctccttg tacccatcct acttttccgg ctttccaacc cttgcccctc agtctctgct
     2161 gtctgggggg ccttccctga aagaacacta gaggggccaa ggggaaggtt tctgctgtgg
     2221 gtgaagccat ctgagaagaa agtccaaccg ggattgaagc tccaggaatc tgaagaatgc
     2281 attctgggtg gttgctaagg gctcagcaac accagaacat ccttggctgt caaggaggcg
     2341 aaggctgcct caggaggctc gactcaggag gcctccacat ggcctatgct catgtcgcct
     2401 ccgaaattcc aaagagcaga catttggact tgccttcctt tgggcatctc tctggtgtgt
     2461 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt acaatgtgtt
     2521 tatgaatgag gaggcctgtg tcaggtctag aggttagatg ttttgtttgc ctttttaatc
     2581 tcatttgttc agacatttga atctcttgtg ttttctagag ctccttgtct ttccccgtcc
     2641 tcttggtcat agtatttgac agttggtttt tttccctccc atccaaagtg tgctcattag
     2701 aggggttctc actgtcaggc agcagcttaa ccccatgttc ttccaggtgc tctgcctaac
     2761 agcgtaaggg gaaattgaac actcagttta cccaaaccac ccactttttt caagctaact
     2821 ggagaagtct ctccatttat tttgaatcca caggcctctg gtaggccgag ataccaccta
     2881 gttatgctgt atctgttttc caaacaggag gtagaggccc ttggagccaa ggcgaccagc
     2941 acaataggtt gctgctagac cgggggaatg atgtttgtgc tgttctccct tctggcccac
     3001 tcctctcaag agcctttctc tttgttcttt tgttcatgtc tgtgtatttt ccctgtggca
     3061 ctggcagtgg ggtacttttt catccagaga aaaacttgtc agtgctccca agaatgaatt
     3121 tccagggatt tgtgggaagg gaaggagcag gggctgtggc agcatgtcct agtgttgcac
     3181 tttgagagga ttgtctactg cagtaataaa cggaaagtat cagcaaga
//
