LOCUS       NM_001034134            1514 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 3,
            subunit L (Eif3l), mRNA.
ACCESSION   NM_001034134
VERSION     NM_001034134.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1514)
  AUTHORS   Lee,A.S., Kranzusch,P.J. and Cate,J.H.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   2  (bases 1 to 1514)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   3  (bases 1 to 1514)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1514)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1514)
  AUTHORS   Powell,M.L., Leigh,K.E., Poyry,T.A., Jackson,R.J., Brown,T.D. and
            Brierley,I.
  TITLE     Further characterisation of the translational
            termination-reinitiation signal of the influenza B virus segment 7
            RNA
  JOURNAL   PLoS One 6 (2), e16822 (2011)
   PUBMED   21347434
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1514)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   7  (bases 1 to 1514)
  AUTHORS   Zhou,M., Sandercock,A.M., Fraser,C.S., Ridlova,G., Stephens,E.,
            Schenauer,M.R., Yokoi-Fong,T., Barsky,D., Leary,J.A., Hershey,J.W.,
            Doudna,J.A. and Robinson,C.V.
  TITLE     Mass spectrometry reveals modularity and a complete subunit
            interaction map of the eukaryotic translation factor eIF3
  JOURNAL   Proc Natl Acad Sci U S A 105 (47), 18139-18144 (2008)
   PUBMED   18599441
REFERENCE   8  (bases 1 to 1514)
  AUTHORS   Masutani,M., Sonenberg,N., Yokoyama,S. and Imataka,H.
  TITLE     Reconstitution reveals the functional core of mammalian eIF3
  JOURNAL   EMBO J 26 (14), 3373-3383 (2007)
   PUBMED   17581632
REFERENCE   9  (bases 1 to 1514)
  AUTHORS   Damoc,E., Fraser,C.S., Zhou,M., Videler,H., Mayeur,G.L.,
            Hershey,J.W., Doudna,J.A., Robinson,C.V. and Leary,J.A.
  TITLE     Structural characterization of the human eukaryotic initiation
            factor 3 protein complex by mass spectrometry
  JOURNAL   Mol Cell Proteomics 6 (7), 1135-1146 (2007)
   PUBMED   17322308
REFERENCE   10 (bases 1 to 1514)
  AUTHORS   Seither,P., Iben,S., Thiry,M. and Grummt,I.
  TITLE     PAF67, a novel protein that is associated with the
            initiation-competent form of RNA polymerase I
  JOURNAL   Biol Chem 382 (8), 1163-1170 (2001)
   PUBMED   11592397
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100264.1.
            
            [WARNING] On Apr 10, 2024 this sequence was replaced by
            NM_001034134.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100264.1, SRR8487227.129484.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1514
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1514
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /note="eukaryotic translation initiation factor 3, subunit
                     L"
                     /db_xref="GeneID:300069"
                     /db_xref="RGD:1308230"
     exon            1..323
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1267
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /note="eukaryotic translation initiation factor 3, subunit
                     6 interacting protein"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit L"
                     /protein_id="NP_001029306.1"
                     /db_xref="GeneID:300069"
                     /db_xref="RGD:1308230"
                     /translation="MPLPHCFLLQQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHS
                     VLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLL
                     GDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLY
                     IQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLR
                     MQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLS
                     TIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSA
                     SEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP"
     exon            324..478
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /inference="alignment:Splign:2.1.0"
     exon            479..649
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /inference="alignment:Splign:2.1.0"
     exon            650..1147
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1228
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1428
                     /gene="Eif3l"
                     /gene_synonym="Eif3s6ip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggatgtgt ggaagtttga ggccacctga gccagatagc tttgctattt ccacctctga
       61 aaagtttaat gaaagcccgt gtcacatcat tctccgcatg tgactgtcac ttggatttat
      121 gcccctgcca cattgtttcc ttctgcaaca gttccagtca ttcagtcagt atcgctgcaa
      181 gacggccaag aagtcagagg aagagatcga cttcctgaga tccaacccta agatctggaa
      241 cgtgcacagc gtcctcaacg tgctgcattc tctggtggac aaatccaaca tcaaccggca
      301 gctggaggtg tacaccagtg gaggtgaccc cgaaagtgtg gctggggaat atggacgaca
      361 ctccctctac aagatgcttg gctacttcag cctggtgggg cttctgcgcc tacattctct
      421 actgggggat tactaccagg ctatcaaggt gctggagaat attgagctaa acaagaaaag
      481 catgtattcc cgtgtgcctg agtgccaggt caccacctac tattatgttg gttttgcata
      541 tttaatgatg cgtcgatacc aggatgctat ccgcgtcttt gccaacatcc tcctgtacat
      601 ccagaggacc aagagtatgt tccagaggac cacatacaag tatgaaatga ttaacaagca
      661 gaatgagcag atgcatgctc tgttggccat tgctctcacc atgtacccca tgaggattga
      721 tgagagcata cacctccagc tgcgggagaa atatggcgac aagatgctgc gcatgcagaa
      781 gggcgacccc caggtctatg aggaactttt cagctatgcc tgccccaagt tcctgtcgcc
      841 tgtggtgcct aactacgaca acgtgcatcc taactaccac aaagagccct tcctgcagca
      901 gctgaaggtg ttttctgatg aagtgcagca gcaggcccag ctctccacca tccgcagctt
      961 cctcaagctc tacaccacca tgcctgtggc caagctggct ggcttcctgg acctcacaga
     1021 gcaggagttc cgcatccaac tgcttgtctt caagcacaag atgaagaacc tggtgtggac
     1081 cagtggcatt tctgccctag atggcgaatt ccagtcggcc tcggaggtgg acttctacat
     1141 tgataaggac atgatccaca tcgcagacac caaagttgcc cgacgctatg gggatttctt
     1201 catccggcag atccacaagt ttgaagagct taatcgaacc ctgaagaaga tgggacagag
     1261 gccctgaaga tgctcataca caagtcaaga acctattttg atattataga tgggaagtat
     1321 tcttgtcacc aagaagcctt acctaagtca gccagcagct gaattgaaac ttgttcaaat
     1381 caaggactgg atgttttaag acgctctcag taaagggtct ctgtcggaaa aaaaaaaaaa
     1441 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1501 aaaaaaaaaa aaaa
//
