LOCUS       NM_198751               1260 bp    mRNA    linear   ROD 31-DEC-2022
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 3,
            subunit H (Eif3h), mRNA.
ACCESSION   NM_198751 XM_216919
VERSION     NM_198751.3
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1260)
  AUTHORS   Lee AS, Kranzusch PJ and Cate JH.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   2  (bases 1 to 1260)
  AUTHORS   Hinnebusch AG.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   3  (bases 1 to 1260)
  AUTHORS   Zeng L, Wan Y, Li D, Wu J, Shao M, Chen J, Hui L, Ji H and Zhu X.
  TITLE     The m subunit of murine translation initiation factor eIF3
            maintains the integrity of the eIF3 complex and is required for
            embryonic development, homeostasis, and organ size control
  JOURNAL   J Biol Chem 288 (42), 30087-30093 (2013)
   PUBMED   24003236
REFERENCE   4  (bases 1 to 1260)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1260)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 1260)
  AUTHORS   Damoc E, Fraser CS, Zhou M, Videler H, Mayeur GL, Hershey JW,
            Doudna JA, Robinson CV and Leary JA.
  TITLE     Structural characterization of the human eukaryotic initiation
            factor 3 protein complex by mass spectrometry
  JOURNAL   Mol Cell Proteomics 6 (7), 1135-1146 (2007)
   PUBMED   17322308
REFERENCE   7  (bases 1 to 1260)
  AUTHORS   Savinainen KJ, Linja MJ, Saramaki OR, Tammela TL, Chang GT,
            Brinkmann AO and Visakorpi T.
  TITLE     Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes
            in breast and prostate cancer
  JOURNAL   Br J Cancer 90 (5), 1041-1046 (2004)
   PUBMED   14997205
REFERENCE   8  (bases 1 to 1260)
  AUTHORS   Saramaki O, Willi N, Bratt O, Gasser TC, Koivisto P, Nupponen NN,
            Bubendorf L and Visakorpi T.
  TITLE     Amplification of EIF3S3 gene is associated with advanced stage in
            prostate cancer
  JOURNAL   Am J Pathol 159 (6), 2089-2094 (2001)
   PUBMED   11733359
REFERENCE   9  (bases 1 to 1260)
  AUTHORS   Nupponen NN, Porkka K, Kakkola L, Tanner M, Persson K, Borg A,
            Isola J and Visakorpi T.
  TITLE     Amplification and overexpression of p40 subunit of eukaryotic
            translation initiation factor 3 in breast and prostate cancer
  JOURNAL   Am J Pathol 154 (6), 1777-1783 (1999)
   PUBMED   10362802
REFERENCE   10 (bases 1 to 1260)
  AUTHORS   Behlke,J., Bommer,U.A., Lutsch,G., Henske,A. and Bielka,H.
  TITLE     Structure of initiation factor eIF-3 from rat liver. Hydrodynamic
            and electron microscopic investigations
  JOURNAL   Eur J Biochem 157 (3), 523-530 (1986)
   PUBMED   3720742
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000185.1.
            
            [WARNING] On Jun 26, 2023 this sequence was replaced by
            NM_198751.4.
            
            On Mar 18, 2021 this sequence version replaced NM_198751.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ216838.1, FQ228544.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               JACYVU010000185.1  65804660-65804831   c
            173-329             JACYVU010000185.1  65781852-65782008   c
            330-497             JACYVU010000185.1  65735228-65735395   c
            498-597             JACYVU010000185.1  65733646-65733745   c
            598-747             JACYVU010000185.1  65732437-65732586   c
            748-868             JACYVU010000185.1  65725843-65725963   c
            869-1001            JACYVU010000185.1  65723946-65724078   c
            1002-1260           JACYVU010000185.1  65721417-65721675   c
FEATURES             Location/Qualifiers
     source          1..1260
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7"
     gene            1..1260
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /note="eukaryotic translation initiation factor 3, subunit
                     H"
                     /db_xref="GeneID:299899"
                     /db_xref="RGD:735178"
     exon            1..172
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1099
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /note="eIF-3-gamma; eIF3 p40 subunit; eukaryotic
                     translation initiation factor 3, subunit 3 gamma, 40kDa;
                     eukaryotic translation initiation factor 3 subunit 3"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit H"
                     /protein_id="NP_942046.1"
                     /db_xref="GeneID:299899"
                     /db_xref="RGD:735178"
                     /translation="MASRKEGTGSTATSSSSTGGAVGKGKGKGGSGDSAVKQVQIDGL
                     VVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQME
                     MMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQG
                     SLSLKAYRLTPKLMEVCKEKDFSPEALKKANITFEHMFEEVPIVIKNSHLINVLMWEL
                     EKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIIKYNTYMRNSSKQQQQKHQ
                     YQQRRQQENMQRQSRGEPPLPEEDLSKLFKPHQAPARMDSLLIAGQINTYCQNIKEFT
                     AQNLGKLFMAQALQEYSN"
     exon            173..329
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
     exon            330..497
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
     exon            498..597
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
     exon            598..747
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
     exon            748..868
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1001
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1260
                     /gene="Eif3h"
                     /gene_synonym="Eif3s3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctcctcac gcttctcttt cttcctgtct ggctggaaac atggcgtcgc gcaaggaagg
       61 caccggttcc accgccacct cttccagctc tactggcggc gcggtgggga agggaaaagg
      121 gaaaggcggc tctggagatt cggccgtgaa gcaggtgcag attgacggcc tggtagtatt
      181 aaagataatc aaacattatc aagaagaagg acaaggaact gaggtcgttc agggagtgct
      241 cctgggcctg gttgtagaag accgactgga gattaccaac tgtttcccat tcccccagca
      301 cacagaggac gatgctgact ttgatgaagt gcagtatcag atggagatga tgcgcagcct
      361 tcgccacgtg aacatcgacc acctccacgt gggctggtac cagtccacgt attacggctc
      421 cttcgttacc cgggcgcttc tggattctca gttcagctac cagcacgcca ttgaagaatc
      481 tgtcgttctc atttacgatc ccataaaaac tgcccaagga tctctctcac tgaaggcata
      541 cagactgact cctaaactga tggaagtttg taaagagaag gacttttccc cggaagcatt
      601 gaaaaaggca aacatcacct ttgaacacat gtttgaagaa gtgccgattg taattaaaaa
      661 ctcacatttg atcaatgtcc tgatgtggga gcttgagaag aagtccgctg tggctgataa
      721 gcatgaattg ctcagtcttg ctagcagcaa tcacttgggg aagaatctgc agttgctgat
      781 ggaccgggtg gatgaaatga gtcaggacat aatcaaatac aacacataca tgaggaacag
      841 cagtaagcag cagcagcaga aacaccagta tcagcagcgt cgccagcagg agaatatgca
      901 gcggcagagt cgaggcgagc ccccgctccc tgaggaggac ctctccaaac tcttcaagcc
      961 ccaccaagcc cctgccagga tggactcgct gctcattgca ggccagatta acacttactg
     1021 ccagaacatc aaggagttca ctgcccaaaa cttaggcaaa ctcttcatgg ctcaggctct
     1081 tcaagaatac agtaactaag aaaaggaagc ttcctgcaaa gaagacagac tgttgagact
     1141 ccaccagagt gactcttgga aaatgtgttt ctgtactgca aagtggagag gcgcactgtg
     1201 ctcttagtgc tgtaatggct ttataaccaa taataaaaag ttacttggtt gttcagttgc
//
