LOCUS       NM_001013095            1070 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 3,
            subunit G (Eif3g), mRNA.
ACCESSION   NM_001013095 XM_216611
VERSION     NM_001013095.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Lee,A.S., Kranzusch,P.J., Doudna,J.A. and Cate,J.H.
  TITLE     eIF3d is an mRNA cap-binding protein that is required for
            specialized translation initiation
  JOURNAL   Nature 536 (7614), 96-99 (2016)
   PUBMED   27462815
REFERENCE   2  (bases 1 to 1070)
  AUTHORS   Lee,A.S., Kranzusch,P.J. and Cate,J.H.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   3  (bases 1 to 1070)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   4  (bases 1 to 1070)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 1070)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 1070)
  AUTHORS   Powell,M.L., Leigh,K.E., Poyry,T.A., Jackson,R.J., Brown,T.D. and
            Brierley,I.
  TITLE     Further characterisation of the translational
            termination-reinitiation signal of the influenza B virus segment 7
            RNA
  JOURNAL   PLoS One 6 (2), e16822 (2011)
   PUBMED   21347434
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1070)
  AUTHORS   Zhou,M., Sandercock,A.M., Fraser,C.S., Ridlova,G., Stephens,E.,
            Schenauer,M.R., Yokoi-Fong,T., Barsky,D., Leary,J.A., Hershey,J.W.,
            Doudna,J.A. and Robinson,C.V.
  TITLE     Mass spectrometry reveals modularity and a complete subunit
            interaction map of the eukaryotic translation factor eIF3
  JOURNAL   Proc Natl Acad Sci U S A 105 (47), 18139-18144 (2008)
   PUBMED   18599441
REFERENCE   8  (bases 1 to 1070)
  AUTHORS   Masutani,M., Sonenberg,N., Yokoyama,S. and Imataka,H.
  TITLE     Reconstitution reveals the functional core of mammalian eIF3
  JOURNAL   EMBO J 26 (14), 3373-3383 (2007)
   PUBMED   17581632
REFERENCE   9  (bases 1 to 1070)
  AUTHORS   Damoc,E., Fraser,C.S., Zhou,M., Videler,H., Mayeur,G.L.,
            Hershey,J.W., Doudna,J.A., Robinson,C.V. and Leary,J.A.
  TITLE     Structural characterization of the human eukaryotic initiation
            factor 3 protein complex by mass spectrometry
  JOURNAL   Mol Cell Proteomics 6 (7), 1135-1146 (2007)
   PUBMED   17322308
REFERENCE   10 (bases 1 to 1070)
  AUTHORS   Bohnsack,M.T., Regener,K., Schwappach,B., Saffrich,R.,
            Paraskeva,E., Hartmann,E. and Gorlich,D.
  TITLE     Exp5 exports eEF1A via tRNA from nuclei and synergizes with other
            transport pathways to confine translation to the cytoplasm
  JOURNAL   EMBO J 21 (22), 6205-6215 (2002)
   PUBMED   12426392
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086383.1.
            
            On Apr 20, 2005 this sequence version replaced XM_216611.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086383.1, FQ232661.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..1070
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /note="eukaryotic translation initiation factor 3, subunit
                     G"
                     /db_xref="GeneID:298700"
                     /db_xref="RGD:1307191"
     exon            1..30
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..973
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /note="eukaryotic translation initiation factor 3, subunit
                     4 (delta); eIF-3 RNA-binding subunit; eukaryotic
                     translation initiation factor 3 subunit 4; eukaryotic
                     translation initiation factor 3 RNA-binding subunit;
                     eIF-3-delta"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit G"
                     /protein_id="NP_001013113.1"
                     /db_xref="GeneID:298700"
                     /db_xref="RGD:1307191"
                     /translation="MPTGDFDSKPSWADQVEEEGEDDKCVTSELLKGIPLPTGDTSPE
                     PELLPGDPLPPPKEVINGNIKTVTEYKVEEDGKKFKIVRTFRIETRKASKAVARRKNW
                     KKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQEEEDPMNKLKGQKIVSCRIC
                     KGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQAAQNKTGKYVPPSL
                     RDGASRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTT
                     GQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN"
     exon            31..77
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            78..161
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            162..250
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            251..310
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            311..415
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            416..605
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            606..713
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            714..850
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            851..957
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1047
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggacttcgag atgccgactg gcgactttga ctcgaagccc agctgggccg accaggtgga
       61 agaggaggga gaggacgaca agtgtgtcac cagcgagctc ctgaaaggaa tccctctgcc
      121 caccggtgac accagtccag agccggagtt acttcctgga gacccactgc cacctcccaa
      181 ggaagtcatc aatgggaaca taaagacggt gactgagtac aaggtagagg aagatgggaa
      241 gaagttcaag attgtcagaa ccttcagaat tgagacccgg aaggcatcaa aggctgtggc
      301 caggaggaag aattggaaga agtttggcaa ctcagagttt gacccgccag ggcccaatgt
      361 agccactacc acagtcagtg atgacgtctc catgacattc atcactagca aagaggacct
      421 gaactgccag gaggaggagg acccaatgaa caagctcaag ggccagaaga tcgtgtcctg
      481 ccgcatttgc aagggcgacc attggaccac ccgctgcccc tacaaggaca cactaggacc
      541 catgcagaag gagctggctg agcagctggg cctgtctacc ggggagaagg agaaattgcc
      601 aggagaactg gagcctgtgc aggccgccca gaacaagaca gggaagtatg tgcctcctag
      661 tctccgggac ggggcaagcc gccgtgggga gtctatgcag ccaaaccgca gagctgatga
      721 caatgccacc atccgtgtca ctaatctgtc tgaggacact cgtgagactg acttacagga
      781 actcttccgg ccttttggct ccatctcccg aatctacttg gccaaggaca agaccactgg
      841 gcagtccaag ggttttgcct ttatcagctt tcaccgccgg gaggatgctg cgcgtgccat
      901 tgcaggggtg tctggctttg gctacgacca tcttatcctc aatgtcgagt gggccaagcc
      961 ttcaacgaat taataagaca tctgctgcct gctgctgttg tccagatcct cagggacaga
     1021 aagcttccag taaacagact ccaaataaaa aaaaaaaaaa aaaaaaaaaa
//
