LOCUS       NP_001013113             320 aa            linear   ROD 03-APR-2024
DEFINITION  eukaryotic translation initiation factor 3 subunit G [Rattus
            norvegicus].
ACCESSION   NP_001013113 XP_216611
VERSION     NP_001013113.1
DBSOURCE    REFSEQ: accession NM_001013095.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 320)
  AUTHORS   Lee,A.S., Kranzusch,P.J., Doudna,J.A. and Cate,J.H.
  TITLE     eIF3d is an mRNA cap-binding protein that is required for
            specialized translation initiation
  JOURNAL   Nature 536 (7614), 96-99 (2016)
   PUBMED   27462815
REFERENCE   2  (residues 1 to 320)
  AUTHORS   Lee,A.S., Kranzusch,P.J. and Cate,J.H.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   3  (residues 1 to 320)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   4  (residues 1 to 320)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (residues 1 to 320)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (residues 1 to 320)
  AUTHORS   Powell,M.L., Leigh,K.E., Poyry,T.A., Jackson,R.J., Brown,T.D. and
            Brierley,I.
  TITLE     Further characterisation of the translational
            termination-reinitiation signal of the influenza B virus segment 7
            RNA
  JOURNAL   PLoS One 6 (2), e16822 (2011)
   PUBMED   21347434
  REMARK    Publication Status: Online-Only
REFERENCE   7  (residues 1 to 320)
  AUTHORS   Zhou,M., Sandercock,A.M., Fraser,C.S., Ridlova,G., Stephens,E.,
            Schenauer,M.R., Yokoi-Fong,T., Barsky,D., Leary,J.A., Hershey,J.W.,
            Doudna,J.A. and Robinson,C.V.
  TITLE     Mass spectrometry reveals modularity and a complete subunit
            interaction map of the eukaryotic translation factor eIF3
  JOURNAL   Proc Natl Acad Sci U S A 105 (47), 18139-18144 (2008)
   PUBMED   18599441
REFERENCE   8  (residues 1 to 320)
  AUTHORS   Masutani,M., Sonenberg,N., Yokoyama,S. and Imataka,H.
  TITLE     Reconstitution reveals the functional core of mammalian eIF3
  JOURNAL   EMBO J 26 (14), 3373-3383 (2007)
   PUBMED   17581632
REFERENCE   9  (residues 1 to 320)
  AUTHORS   Damoc,E., Fraser,C.S., Zhou,M., Videler,H., Mayeur,G.L.,
            Hershey,J.W., Doudna,J.A., Robinson,C.V. and Leary,J.A.
  TITLE     Structural characterization of the human eukaryotic initiation
            factor 3 protein complex by mass spectrometry
  JOURNAL   Mol Cell Proteomics 6 (7), 1135-1146 (2007)
   PUBMED   17322308
REFERENCE   10 (residues 1 to 320)
  AUTHORS   Bohnsack,M.T., Regener,K., Schwappach,B., Saffrich,R.,
            Paraskeva,E., Hartmann,E. and Gorlich,D.
  TITLE     Exp5 exports eEF1A via tRNA from nuclei and synergizes with other
            transport pathways to confine translation to the cytoplasm
  JOURNAL   EMBO J 21 (22), 6205-6215 (2002)
   PUBMED   12426392
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086383.1.
            
            On Apr 20, 2005 this sequence version replaced XP_216611.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086383.1, FQ232661.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     Protein         1..320
                     /product="eukaryotic translation initiation factor 3
                     subunit G"
                     /note="eukaryotic translation initiation factor 3, subunit
                     4 (delta); eIF-3 RNA-binding subunit; eukaryotic
                     translation initiation factor 3 subunit 4; eukaryotic
                     translation initiation factor 3 RNA-binding subunit;
                     eIF-3-delta"
                     /calculated_mol_wt=35520
     Region          1..60
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5RK09.1)"
     Site            8
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O75821; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     Site            11
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O75821; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     Site            38
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:O75821,
                     ECO:0000255|HAMAP-Rule:MF_03006; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     Site            41
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     Site            42
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     Region          62..173
                     /region_name="eIF3G"
                     /note="eIF3G domain found in eukaryotic translation
                     initiation factor 3 subunit G (eIF-3G) and similar
                     proteins; cd12933"
                     /db_xref="CDD:240597"
     Site            189
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O75821; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     Region          205..233
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5RK09.1)"
     Site            223
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O75821; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     Region          240..315
                     /region_name="RRM_eIF3G_like"
                     /note="RNA recognition motif (RRM) found in eukaryotic
                     translation initiation factor 3 subunit G (eIF-3G) and
                     similar proteins; cd12408"
                     /db_xref="CDD:409842"
     Site            264
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O75821; propagated from
                     UniProtKB/Swiss-Prot (Q5RK09.1)"
     CDS             1..320
                     /gene="Eif3g"
                     /gene_synonym="eIF3 p42; eIF3 p44; Eif3s4"
                     /coded_by="NM_001013095.1:11..973"
                     /db_xref="GeneID:298700"
                     /db_xref="RGD:1307191"
ORIGIN      
        1 mptgdfdskp swadqveeeg eddkcvtsel lkgiplptgd tspepellpg dplpppkevi
       61 ngniktvtey kveedgkkfk ivrtfrietr kaskavarrk nwkkfgnsef dppgpnvatt
      121 tvsddvsmtf itskedlncq eeedpmnklk gqkivscric kgdhwttrcp ykdtlgpmqk
      181 elaeqlglst gekeklpgel epvqaaqnkt gkyvppslrd gasrrgesmq pnrraddnat
      241 irvtnlsedt retdlqelfr pfgsisriyl akdkttgqsk gfafisfhrr edaaraiagv
      301 sgfgydhlil nvewakpstn
//
