LOCUS       NM_001004283            1870 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 3,
            subunit D (Eif3d), mRNA.
ACCESSION   NM_001004283 XM_343283
VERSION     NM_001004283.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Lee,A.S., Kranzusch,P.J., Doudna,J.A. and Cate,J.H.
  TITLE     eIF3d is an mRNA cap-binding protein that is required for
            specialized translation initiation
  JOURNAL   Nature 536 (7614), 96-99 (2016)
   PUBMED   27462815
REFERENCE   2  (bases 1 to 1870)
  AUTHORS   Lee,A.S., Kranzusch,P.J. and Cate,J.H.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   3  (bases 1 to 1870)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   4  (bases 1 to 1870)
  AUTHORS   Villa,N., Do,A., Hershey,J.W. and Fraser,C.S.
  TITLE     Human eukaryotic initiation factor 4G (eIF4G) protein binds to
            eIF3c, -d, and -e to promote mRNA recruitment to the ribosome
  JOURNAL   J Biol Chem 288 (46), 32932-32940 (2013)
   PUBMED   24092755
REFERENCE   5  (bases 1 to 1870)
  AUTHORS   Zeng,L., Wan,Y., Li,D., Wu,J., Shao,M., Chen,J., Hui,L., Ji,H. and
            Zhu,X.
  TITLE     The m subunit of murine translation initiation factor eIF3
            maintains the integrity of the eIF3 complex and is required for
            embryonic development, homeostasis, and organ size control
  JOURNAL   J Biol Chem 288 (42), 30087-30093 (2013)
   PUBMED   24003236
REFERENCE   6  (bases 1 to 1870)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   7  (bases 1 to 1870)
  AUTHORS   Zhou,M., Sandercock,A.M., Fraser,C.S., Ridlova,G., Stephens,E.,
            Schenauer,M.R., Yokoi-Fong,T., Barsky,D., Leary,J.A., Hershey,J.W.,
            Doudna,J.A. and Robinson,C.V.
  TITLE     Mass spectrometry reveals modularity and a complete subunit
            interaction map of the eukaryotic translation factor eIF3
  JOURNAL   Proc Natl Acad Sci U S A 105 (47), 18139-18144 (2008)
   PUBMED   18599441
REFERENCE   8  (bases 1 to 1870)
  AUTHORS   Masutani,M., Sonenberg,N., Yokoyama,S. and Imataka,H.
  TITLE     Reconstitution reveals the functional core of mammalian eIF3
  JOURNAL   EMBO J 26 (14), 3373-3383 (2007)
   PUBMED   17581632
REFERENCE   9  (bases 1 to 1870)
  AUTHORS   Damoc,E., Fraser,C.S., Zhou,M., Videler,H., Mayeur,G.L.,
            Hershey,J.W., Doudna,J.A., Robinson,C.V. and Leary,J.A.
  TITLE     Structural characterization of the human eukaryotic initiation
            factor 3 protein complex by mass spectrometry
  JOURNAL   Mol Cell Proteomics 6 (7), 1135-1146 (2007)
   PUBMED   17322308
REFERENCE   10 (bases 1 to 1870)
  AUTHORS   Sizova,D.V., Kolupaeva,V.G., Pestova,T.V., Shatsky,I.N. and
            Hellen,C.U.
  TITLE     Specific interaction of eukaryotic translation initiation factor 3
            with the 5' nontranslated regions of hepatitis C virus and
            classical swine fever virus RNAs
  JOURNAL   J Virol 72 (6), 4775-4782 (1998)
   PUBMED   9573242
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079005.1.
            
            On Sep 10, 2004 this sequence version replaced XM_343283.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079005.1, SRR8487230.72996.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1870
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /note="eukaryotic translation initiation factor 3, subunit
                     D"
                     /db_xref="GeneID:362952"
                     /db_xref="RGD:1303255"
     exon            1..79
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            80..212
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..1736
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /note="eIF-3-zeta; eukaryotic translation initiation
                     factor 3, subunit 7 (zeta); eukaryotic translation
                     initiation factor 3 subunit 7"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit D"
                     /protein_id="NP_001004283.1"
                     /db_xref="GeneID:362952"
                     /db_xref="RGD:1303255"
                     /translation="MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVAD
                     WTGATYQDKRYTNKYSSQFGGGSQYAYFHEEDETSFQLVDTARTQKTAYQRNRMRFAQ
                     RNLRRDKDRRNMVQFNLQTLPKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDS
                     SVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLR
                     SIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSKL
                     FFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGRER
                     YNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFIN
                     IKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLG
                     YVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLI
                     LKDPNKQVIRVYSLPDGTFSSEEDEEDEEEEEEEEEEEET"
     exon            213..258
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            259..395
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            396..481
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            482..554
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            555..667
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            668..800
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            801..948
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1079
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1165
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1295
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1438
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..1722
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1845
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccctgcga gtatcgaggc tatcgcagtt tcttacccgg gctatctgtc gccatccggg
       61 cccgcggagg ccgttgcagg ttttagaaga tggcgaagtt tatgacacct gtgatccagg
      121 acaacccctc aggctggggt ccctgtgccg ttcctgagca gtttcgggat atgccctacc
      181 agccattcag caaaggagat cggctgggga aggttgcaga ctggacaggg gccacgtacc
      241 aggacaagag gtacacaaac aagtattcct ctcagttcgg tgggggaagt cagtatgcat
      301 atttccacga ggaggatgag acgagcttcc agctagtgga cacagcgcgt acacagaaga
      361 cggcctacca gcggaaccgg atgagattcg cacagcggaa cctccgcaga gacaaagacc
      421 ggcggaacat ggtgcagttc aacctacaga cactgcccaa aagtgccaag cagaaagaga
      481 gagaacgaat tcgcttacag aaaaaattcc agaagcaatt tggagtgagg caaaaatggg
      541 accagaagtc acagaaaccc cgagactcct cggttgaagt tcgcagtgac tgggaggtga
      601 aggaggagat ggacttccct cagctgatga agatgcgcta cttggaggtg tcagagcctc
      661 aagacatcga gtgctgtgga gcactggagt actatgacaa agccttcgac cgcatcacca
      721 cgaggagtga gaagcctctg cggagcatca agcgcatctt ccacactgtc accaccacag
      781 acgaccctgt catccggaag ctggcaaaaa cgcagggcaa tgtgtttgcc acagatgcca
      841 tcctggccac actgatgagc tgcacccgct ccgtgtactc ctgggacatt gttgtccaga
      901 gggtcggatc taaactcttc tttgacaaga gggacaattc tgactttgac ctcctgactg
      961 tgagtgagac ggctaacgag ccccctcaag atgaaggcaa ttccttcaac tcaccccgga
     1021 acctggccat ggaggccacc tacatcaacc acaacttctc ccagcagtgc ctgagaatgg
     1081 ggagagagag atacaatttc cccaacccaa acccatttgt ggaggatgac atggataaga
     1141 atgagatcgc ctccgtggct taccgttacc ggaggtggaa gcttggagat gacattgacc
     1201 ttattgttcg ctgtgaacat gatggcgtca tgactggggc caacggggaa gtgtccttca
     1261 tcaacatcaa gacactcaat gaatgggact ccaggcattg taatggcgtt gactggcgtc
     1321 agaagctgga ctctcagcgt ggggctgtca tcgccactga gttgaagaac aacagctaca
     1381 agttggcgcg atggacgtgc tgtgctttgc tggctggctc tgagtacttg aagctcgggt
     1441 atgtgtcccg gtaccatgta aaggactcct cgcgccacgt catcctgggc acccagcagt
     1501 ttaagcccaa tgagtttgcc agccaaatca acctgagtgt ggagaatgcc tggggcatcc
     1561 tgcgctgtgt cattgatatc tgcatgaagc tggaggaggg caaatacctc atcctcaagg
     1621 accccaacaa gcaggtcatc cgagtctaca gcttgcctga tggcaccttc agctctgagg
     1681 aggacgaaga ggatgaggag gaagaggagg aagaagaaga agaggaagaa acttaagtga
     1741 gttggcctgg tgcctgcgtg tgttagcacc tagctgtgcc tgggcagcgt gtgtccagct
     1801 cctgttctct agcagaagaa ataaaattta agtccttttg gtttcaaaaa aaaaaaaaaa
     1861 aaaaaaaaaa
//
