LOCUS       NP_001004283             548 aa            linear   ROD 03-APR-2024
DEFINITION  eukaryotic translation initiation factor 3 subunit D [Rattus
            norvegicus].
ACCESSION   NP_001004283 XP_343284
VERSION     NP_001004283.1
DBSOURCE    REFSEQ: accession NM_001004283.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 548)
  AUTHORS   Lee,A.S., Kranzusch,P.J., Doudna,J.A. and Cate,J.H.
  TITLE     eIF3d is an mRNA cap-binding protein that is required for
            specialized translation initiation
  JOURNAL   Nature 536 (7614), 96-99 (2016)
   PUBMED   27462815
REFERENCE   2  (residues 1 to 548)
  AUTHORS   Lee,A.S., Kranzusch,P.J. and Cate,J.H.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   3  (residues 1 to 548)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   4  (residues 1 to 548)
  AUTHORS   Villa,N., Do,A., Hershey,J.W. and Fraser,C.S.
  TITLE     Human eukaryotic initiation factor 4G (eIF4G) protein binds to
            eIF3c, -d, and -e to promote mRNA recruitment to the ribosome
  JOURNAL   J Biol Chem 288 (46), 32932-32940 (2013)
   PUBMED   24092755
REFERENCE   5  (residues 1 to 548)
  AUTHORS   Zeng,L., Wan,Y., Li,D., Wu,J., Shao,M., Chen,J., Hui,L., Ji,H. and
            Zhu,X.
  TITLE     The m subunit of murine translation initiation factor eIF3
            maintains the integrity of the eIF3 complex and is required for
            embryonic development, homeostasis, and organ size control
  JOURNAL   J Biol Chem 288 (42), 30087-30093 (2013)
   PUBMED   24003236
REFERENCE   6  (residues 1 to 548)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   7  (residues 1 to 548)
  AUTHORS   Zhou,M., Sandercock,A.M., Fraser,C.S., Ridlova,G., Stephens,E.,
            Schenauer,M.R., Yokoi-Fong,T., Barsky,D., Leary,J.A., Hershey,J.W.,
            Doudna,J.A. and Robinson,C.V.
  TITLE     Mass spectrometry reveals modularity and a complete subunit
            interaction map of the eukaryotic translation factor eIF3
  JOURNAL   Proc Natl Acad Sci U S A 105 (47), 18139-18144 (2008)
   PUBMED   18599441
REFERENCE   8  (residues 1 to 548)
  AUTHORS   Masutani,M., Sonenberg,N., Yokoyama,S. and Imataka,H.
  TITLE     Reconstitution reveals the functional core of mammalian eIF3
  JOURNAL   EMBO J 26 (14), 3373-3383 (2007)
   PUBMED   17581632
REFERENCE   9  (residues 1 to 548)
  AUTHORS   Damoc,E., Fraser,C.S., Zhou,M., Videler,H., Mayeur,G.L.,
            Hershey,J.W., Doudna,J.A., Robinson,C.V. and Leary,J.A.
  TITLE     Structural characterization of the human eukaryotic initiation
            factor 3 protein complex by mass spectrometry
  JOURNAL   Mol Cell Proteomics 6 (7), 1135-1146 (2007)
   PUBMED   17322308
REFERENCE   10 (residues 1 to 548)
  AUTHORS   Sizova,D.V., Kolupaeva,V.G., Pestova,T.V., Shatsky,I.N. and
            Hellen,C.U.
  TITLE     Specific interaction of eukaryotic translation initiation factor 3
            with the 5' nontranslated regions of hepatitis C virus and
            classical swine fever virus RNAs
  JOURNAL   J Virol 72 (6), 4775-4782 (1998)
   PUBMED   9573242
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079005.1.
            
            On Sep 10, 2004 this sequence version replaced XP_343284.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079005.1, SRR8487230.72996.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     Protein         1..548
                     /product="eukaryotic translation initiation factor 3
                     subunit D"
                     /note="eIF-3-zeta; eukaryotic translation initiation
                     factor 3, subunit 7 (zeta); eukaryotic translation
                     initiation factor 3 subunit 7"
                     /calculated_mol_wt=63858
     Region          4..521
                     /region_name="eIF-3_zeta"
                     /note="Eukaryotic translation initiation factor 3 subunit
                     7 (eIF-3); pfam05091"
                     /db_xref="CDD:461547"
     Site            53
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:O70194; propagated from
                     UniProtKB/Swiss-Prot (Q6AYK8.1)"
     Site            161
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O15371; propagated from
                     UniProtKB/Swiss-Prot (Q6AYK8.1)"
     Region          285..299
                     /region_name="RNA gate.
                     /evidence=ECO:0000250|UniProtKB:K7IM66"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AYK8.1)"
     Region          523..548
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6AYK8.1)"
     Site            528
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q6AYK8.1)"
     Site            529
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q6AYK8.1)"
     CDS             1..548
                     /gene="Eif3d"
                     /gene_synonym="Eif3s7"
                     /coded_by="NM_001004283.1:90..1736"
                     /db_xref="GeneID:362952"
                     /db_xref="RGD:1303255"
ORIGIN      
        1 makfmtpviq dnpsgwgpca vpeqfrdmpy qpfskgdrlg kvadwtgaty qdkrytnkys
       61 sqfgggsqya yfheedetsf qlvdtartqk tayqrnrmrf aqrnlrrdkd rrnmvqfnlq
      121 tlpksakqke rerirlqkkf qkqfgvrqkw dqksqkprds svevrsdwev keemdfpqlm
      181 kmrylevsep qdieccgale yydkafdrit trsekplrsi krifhtvttt ddpvirklak
      241 tqgnvfatda ilatlmsctr svyswdivvq rvgsklffdk rdnsdfdllt vsetaneppq
      301 degnsfnspr nlameatyin hnfsqqclrm grerynfpnp npfveddmdk neiasvayry
      361 rrwklgddid livrcehdgv mtgangevsf iniktlnewd srhcngvdwr qkldsqrgav
      421 iatelknnsy klarwtccal lagseylklg yvsryhvkds srhvilgtqq fkpnefasqi
      481 nlsvenawgi lrcvidicmk leegkylilk dpnkqvirvy slpdgtfsse edeedeeeee
      541 eeeeeeet
//
