LOCUS       NM_001031640            2948 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 3,
            subunit B (Eif3b), mRNA.
ACCESSION   NM_001031640 XM_221957
VERSION     NM_001031640.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2948)
  AUTHORS   Lee,A.S., Kranzusch,P.J., Doudna,J.A. and Cate,J.H.
  TITLE     eIF3d is an mRNA cap-binding protein that is required for
            specialized translation initiation
  JOURNAL   Nature 536 (7614), 96-99 (2016)
   PUBMED   27462815
REFERENCE   2  (bases 1 to 2948)
  AUTHORS   Lee,A.S., Kranzusch,P.J. and Cate,J.H.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   3  (bases 1 to 2948)
  AUTHORS   Milochau,A., Lagree,V., Benassy,M.N., Chaignepain,S., Papin,J.,
            Garcia-Arcos,I., Lajoix,A., Monterrat,C., Coudert,L.,
            Schmitter,J.M., Ochoa,B. and Lang,J.
  TITLE     Synaptotagmin 11 interacts with components of the RNA-induced
            silencing complex RISC in clonal pancreatic beta-cells
  JOURNAL   FEBS Lett 588 (14), 2217-2222 (2014)
   PUBMED   24882364
REFERENCE   4  (bases 1 to 2948)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   5  (bases 1 to 2948)
  AUTHORS   Zeng,L., Wan,Y., Li,D., Wu,J., Shao,M., Chen,J., Hui,L., Ji,H. and
            Zhu,X.
  TITLE     The m subunit of murine translation initiation factor eIF3
            maintains the integrity of the eIF3 complex and is required for
            embryonic development, homeostasis, and organ size control
  JOURNAL   J Biol Chem 288 (42), 30087-30093 (2013)
   PUBMED   24003236
REFERENCE   6  (bases 1 to 2948)
  AUTHORS   Damoc,E., Fraser,C.S., Zhou,M., Videler,H., Mayeur,G.L.,
            Hershey,J.W., Doudna,J.A., Robinson,C.V. and Leary,J.A.
  TITLE     Structural characterization of the human eukaryotic initiation
            factor 3 protein complex by mass spectrometry
  JOURNAL   Mol Cell Proteomics 6 (7), 1135-1146 (2007)
   PUBMED   17322308
REFERENCE   7  (bases 1 to 2948)
  AUTHORS   Hoffert,J.D., Pisitkun,T., Wang,G., Shen,R.F. and Knepper,M.A.
  TITLE     Quantitative phosphoproteomics of vasopressin-sensitive renal
            cells: regulation of aquaporin-2 phosphorylation at two sites
  JOURNAL   Proc Natl Acad Sci U S A 103 (18), 7159-7164 (2006)
   PUBMED   16641100
REFERENCE   8  (bases 1 to 2948)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   9  (bases 1 to 2948)
  AUTHORS   Sizova,D.V., Kolupaeva,V.G., Pestova,T.V., Shatsky,I.N. and
            Hellen,C.U.
  TITLE     Specific interaction of eukaryotic translation initiation factor 3
            with the 5' nontranslated regions of hepatitis C virus and
            classical swine fever virus RNAs
  JOURNAL   J Virol 72 (6), 4775-4782 (1998)
   PUBMED   9573242
REFERENCE   10 (bases 1 to 2948)
  AUTHORS   Methot,N., Rom,E., Olsen,H. and Sonenberg,N.
  TITLE     The human homologue of the yeast Prt1 protein is an integral part
            of the eukaryotic initiation factor 3 complex and interacts with
            p170
  JOURNAL   J Biol Chem 272 (2), 1110-1116 (1997)
   PUBMED   8995410
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098728.1.
            
            On Aug 12, 2005 this sequence version replaced XM_221957.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098728.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2948
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..2948
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /note="eukaryotic translation initiation factor 3, subunit
                     B"
                     /db_xref="GeneID:288516"
                     /db_xref="RGD:1309018"
     exon            1..476
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..2422
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /note="eukaryotic translation initiation factor 3, subunit
                     9 (eta); eIF-3-eta; eukaryotic translation initiation
                     factor 3 subunit 9"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit B"
                     /protein_id="NP_001026810.1"
                     /db_xref="GeneID:288516"
                     /db_xref="RGD:1309018"
                     /translation="MQDAENVAAPEAAEERAEPARQQPVSESPPTDEAAGSGGSEVGR
                     TEDAEEDAEARPEPEVRAKPAAQSEEETAASPAASPTPQSAQEPSAPGKAEAGGEQAR
                     HPSARAEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRP
                     QEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPEEDGKTKGYIFL
                     EYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNL
                     RYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLAT
                     FHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDI
                     LTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGI
                     KDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDY
                     LCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGE
                     APRISVSFYHVKSNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTS
                     DCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRF
                     CQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDF
                     RQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE"
     exon            477..669
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            670..789
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            790..847
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            848..976
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1134
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1266
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1333
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1380
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1591
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..1664
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1787
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1866
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..2005
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2131
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2209
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            2210..2318
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            2319..2435
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
     exon            2436..2922
                     /gene="Eif3b"
                     /gene_synonym="Eif3s9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagccgggt gaggagcagc gcgggcccat gcaggacgct gagaacgtgg cggcgcccga
       61 ggcggccgag gagcgggccg agcccgcgag gcagcagccg gtctccgagt caccgccgac
      121 ggacgaggcg gcagggtctg gcgggtccga agtggggcgg acggaagacg ccgaggaaga
      181 cgccgaggcc agaccggagc ccgaggtgag ggccaagccg gcggcccaat ccgaagagga
      241 aacggcggcg agtccggccg cctcgcccac gccgcagtcg gcgcaggagc cctctgctcc
      301 cgggaaggcg gaggccggcg gagagcaggc caggcacccc tcggctagag cggaggagga
      361 gggcgggtcc gatgggagcg cggccgaggc ggagccgcgg gctctggaga acggagaggc
      421 agatgagccc tccttcagcg accccgagga tttcgtagac gacgtgagcg aggaagaact
      481 acttggtgat gtactcaaag atcggcctca ggaagcggat gggattgact cggtgattgt
      541 tgtagacaac gttcctcagg tgggacccga ccggcttgag aagctcaaaa atgtcatcca
      601 caagatcttc tccaagtttg ggaaaatcat aaatgactat taccctgaag aggatggaaa
      661 gacgaaaggg tacatctttc tggaatatgc ttctcccgcc catgctgtgg atgctgtgaa
      721 aaatgcagat ggatacaagc tggacaagca gcacacgttc cgggtcaacc tcttcactga
      781 ttttgataag tacatgacca tcagtgacga gtgggacatc ccagagaagc agcctttcaa
      841 agacctgggc aatctgcgct attggctgga agaggcagag tgtagagatc agtacagtgt
      901 gatttttgag agcggagacc ggacatccat cttctggaat gacgtcaagg acccagtctc
      961 aatcgaagaa agagcgagat ggacagagac atatgtgcgc tggtccccta agggcaccta
     1021 cctggccacc ttccatcagc ggggtatcgc cctctgggga ggggacaagt tcaagcagat
     1081 ccagaggttc agccaccaag gcgtgcagct catcgatttc tcaccttgtg aaagatacct
     1141 ggtgactttc agcccactga tggacactca ggatgaccct caggccatca ttatctggga
     1201 catcctcaca gggcataaga agagaggttt tcactgtgaa agctcagccc actggcccat
     1261 cttcaagtgg agccatgatg gcaaattctt tgcaagaatg accctggata cccttagcat
     1321 ctatgaaaca ccttccatgg gccttttgga caagaagagc ttgaagatct ctggaataaa
     1381 agacttttct tggtctccgg gtggtaacat cattgccttt tgggtgccag aagacaaaga
     1441 tattccagcc agggtgaccc tgatgcagct ccccaccaga caggagatcc gagtgaggaa
     1501 tttgttcaat gtggttgatt gcaagctgca ctggcagaaa aatggagatt acctgtgtgt
     1561 aaaagtggac aggactccaa aaggcacaca gggagttgtc acaaattttg aaatcttccg
     1621 aatgagggag aagcaggttc ctgttgacgt tgttgagatg aaagagacca tcatagcctt
     1681 tgcctgggaa cccaatggca gtaagtttgc tgtgcttcat ggtgaggccc ctcggatatc
     1741 tgtctccttc taccacgtga agagcaatgg gaagattgaa ctcatcaaga tgtttgacaa
     1801 gcagcaagcc aataccatct tctggagtcc ccaggggcag ttcgtggtac tggccgggct
     1861 gaggagcatg aatggcgcct tggcgtttgt cgacacttca gactgcaccg tcatgaacat
     1921 tgcagagcac tacatggcct ccgacgtcga atgggaccca actggccgct atgtggttac
     1981 ctctgtgtcg tggtggagcc ataaggtgga caatgcttat tggctgtgga ccttccaagg
     2041 tcgtcttctc cagaagaaca acaaggaccg cttctgccag ctgctctgga gaccaaggcc
     2101 cccaacactc ctcagtcagg atcagataaa gcaaattaaa aaggatctga agaaatactc
     2161 taagatcttt gagcagaagg atcgcttgag ccagtccaaa gcttcaaagg aactggtgga
     2221 aagaaggcgg accatgatgg aggacttcag gcaataccga aaaatggccc aggaactcta
     2281 tatgaagcag aagaacgagc gtctagagct acggggaggg gtggacactg acgagctgga
     2341 cagcaacgtg gatgactggg aggaagagac cattgagttt tttgtcactg aagaggtcat
     2401 tcctctggga agtcaggagt gacctcagca ctgtgtgtca ctgtgccgtg cccaagatcc
     2461 aaggccacac tcttcacaga gagcctcggg ctgggttctc acctgtgctt tcgtgctctg
     2521 gactgcgagt gcacccaggg ttcttccatc ccgacacagc tctgtgcctt cagccccggg
     2581 tcctcagcgg ggacactcga gcctctgctc tcacaatgcc ctgtttgggt ttttatcagc
     2641 cctgtctgca ttggagcctc actgcagtgt tcctggtggc tcctttaact cctgctgctg
     2701 cccatggggt ttccagagcc tccacttcca gctcagtggg atttccattc atggacttgc
     2761 tgttcctgtg tgggccagtg tcatgtggcc atcaggaagt ctgcacaccc aacacttact
     2821 gtgccagaaa ctctggaggc acccagcacc tcacagctgt tcaggttgtg gcagggcctc
     2881 tgctcaagtt ggatgtggaa ataaaagcaa ccctgtgtga aaaaaaaaaa aaaaaaaaaa
     2941 aaaaaaaa
//
