LOCUS       NM_001008773            2818 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 1A
            (Eif1a), transcript variant 1, mRNA.
ACCESSION   NM_001008773 XM_228399
VERSION     NM_001008773.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2818)
  AUTHORS   Andreev,D.E., O'Connor,P.B., Zhdanov,A.V., Dmitriev,R.I.,
            Shatsky,I.N., Papkovsky,D.B. and Baranov,P.V.
  TITLE     Oxygen and glucose deprivation induces widespread alterations in
            mRNA translation within 20 minutes
  JOURNAL   Genome Biol 16 (1), 90 (2015)
   PUBMED   25943107
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2818)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   3  (bases 1 to 2818)
  AUTHORS   Wu,X., Liu,W.Y., Xu,L. and Li,M.
  TITLE     Topography of ribosomes and initiation complexes from rat liver as
            revealed by atomic force microscopy
  JOURNAL   Biol Chem 378 (5), 363-372 (1997)
   PUBMED   9191023
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On May 14, 2021 this sequence version replaced NM_001008773.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC093607.1, SRR26643288.59486.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               JAXUCZ010000018.1  41512298-41512485
            189-235             JAXUCZ010000018.1  41513334-41513380
            236-2818            JAXUCZ010000018.1  41522063-41524645
FEATURES             Location/Qualifiers
     source          1..2818
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q11"
     gene            1..2818
                     /gene="Eif1a"
                     /note="eukaryotic translation initiation factor 1A"
                     /db_xref="GeneID:317163"
                     /db_xref="RGD:1306331"
     exon            1..188
                     /gene="Eif1a"
                     /inference="alignment:Splign:2.1.0"
     exon            189..235
                     /gene="Eif1a"
                     /inference="alignment:Splign:2.1.0"
     exon            236..2818
                     /gene="Eif1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             417..851
                     /gene="Eif1a"
                     /note="Ab1-287; X-linked eukaryotic translation initiation
                     factor 1A; eIF-1A; eIF-4C; liver regeneration-related
                     protein LRRG048; eukaryotic translation initiation factor
                     4C"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 1A"
                     /protein_id="NP_001008773.3"
                     /db_xref="GeneID:317163"
                     /db_xref="RGD:1306331"
                     /translation="MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGN
                     GRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARS
                     LKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI"
ORIGIN      
        1 gcgttgtagt gaggacgtgg aagagcgtga ggcctcggcg ttgcgtgggc ggccctcctt
       61 gggcgagggg agggggcagt gcgggaactc gacgggaagg ggcgtggccg gccgttgcct
      121 aggaagggcg cgtggtctcg ctgctcgccg ggctgagacg gtagaggggt tctgctgcat
      181 ttgtcactac tgggaagact agaccttcct gagagccagg ccagaaattt tgtagctgtt
      241 agaagccagg actctggaac actgtttgct gcttgtggat cttctatact tacagtgtcg
      301 ctattcagtc acttcagatc tgccactatt aagagacttc ctgccaccca tcctagcagt
      361 cacagtcact gtcagcaggg actcctcacc caacccctgt ggttgccatc ttcatcatgc
      421 caaagaataa aggcaaagga ggcaaaaaca ggcgcagagg taaaaatgaa aatgaatctg
      481 agaagagaga gttagtgttt aaagaggatg ggcaagagta tgctcaggtg atcaaaatgc
      541 tgggaaacgg acggttggaa gcaatgtgct ttgacggtgt gcggaggctg tgccacataa
      601 gagggaagtt gagaaaaaag gtttggataa acacctcaga cattatactg attggtctac
      661 gagactacca agacaacaag gctgacgtaa tcttaaagta caatgcagac gaagcaagaa
      721 gtctgaaggc atatggagaa cttccagaac atgccaaaat caatgaaacg gacacatttg
      781 gtcctgggga tgacgatgaa atccagtttg atgatattgg agatgatgat gaagacattg
      841 atgatatcta acctgaccta agcacgttac atttcaagtt ctctgaagat agctctacac
      901 aattgggatc ttgacgttca gctgttaagt aaaacttcat ttggcatgtg tatgacttgt
      961 taatgcaaat tgatgaattt tattttttga agtattatat ttctttgaaa accaaagatg
     1021 ttgagttatc ttaagtgaca tgttaacact ttgtgcttct ggatgtaatt gaacttaggg
     1081 cacagcagtg tgcactgtta agagactgcc tttccatttg tgatgcttca tttctggcac
     1141 gtgagtgttt tgtgtcagca gttctgccgg gtgaccaccg taggctggag taagtcctgg
     1201 tccagcacac ctgctttaga cgctaattgt ccggctgcat ttgagacgtc tcaaagttag
     1261 acaggatatg gctatttttg tatttatgga gccatgccat tttatactta ctacgtgaag
     1321 ttccatacat tcattttacc ctataagttg ttgtcatcca taaaaaaaat cttacagtgc
     1381 aatttttaaa ttttatgggt agcaattttg agttttaaaa attagtcatt gcaaaaatta
     1441 aatacttaga ggagataatc cattatcttg actttacaaa taaagtagtt gacaatgttt
     1501 atatgtaatt ttacttttct aaggcatacc caaaaaatag gaaatgaaaa ttaaaagaga
     1561 agtaaatctg ttctgatact tgcatagaga aattttcaaa gaaggtagtt gttaatattt
     1621 tgtgttaagt cattttcaaa aagttagcta ctgtattgag gcttgcataa ttactatgta
     1681 ttgattaaag ttagttacat aattgtacga gggaagtttt ccttaaacta agcttaggtt
     1741 aaaggaaaag gagccacagc ttaatgaaac cgtggttcct attttctaaa tggaggagtc
     1801 tagaaacaaa caataaaaac atgttggtat aaaaacattt tttcttttta atatgttcat
     1861 tatatctctg gtatataaca aaaataaatg actggatgat ttctagtata tcatgagagg
     1921 cttttttttt ttttttaatt agacactggg atttaagata aacaactatt ttcccattta
     1981 agtaatgctg gtatcagggt tctgcagttt aactcttgct gcttaggaag taagtataac
     2041 cttgctatta gtcctcagat gccttttaaa agaatagttc ctttctcagg ctttgttcta
     2101 gataccttca aatggtgcct gagcatgaaa acaacagtat tcaccttcac ttttgttttt
     2161 tgttttccag ttagcccata ataatgtagc ttaaggaaat tacccagtca aaaagaaaga
     2221 aaagcaaata acagttttct tgatcattga ttggtgactc ttctagatgc tgatgtagat
     2281 ctttgtaaag gttaattttg taaaatgagc tagacatggt gccagattag agtcagatcc
     2341 cacctcccca gaaggacagt gtgtctttag aaagagaaca tcactggagc tttttattgc
     2401 tatacacagt gcatctgaat atactgttaa cctaagattt atcccattgc tgccgtacat
     2461 tttagtacag gaagaaaatt tgaccatggg ccagctagct tgatgcattc aacagcaaac
     2521 aagattatct caagttagga ggtgaggacc agtgcctgaa gatgtcctct cagtccacaa
     2581 catgtacaca acatatatgc atcagacatg tacaaagttg cacttgatga ggctatagta
     2641 tcatgtcttg gtcattgcaa actatcagag gcaaacactg aggtatttac attgcctgtt
     2701 taccaatatc taatttcaat cacattctag atgaaggaat gattctttta taacatgagt
     2761 gatttatgct gtaaatgttg acataagtgt tagaattaaa atgacttgta gtgaaata
//
