LOCUS       NM_001105837            1074 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus eukaryotic translation initiation factor 1
            (Eif1), mRNA.
ACCESSION   NM_001105837 XM_001081454 XM_213456
VERSION     NM_001105837.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Hinnebusch,A.G.
  TITLE     The scanning mechanism of eukaryotic translation initiation
  JOURNAL   Annu Rev Biochem 83, 779-812 (2014)
   PUBMED   24499181
  REMARK    Review article
REFERENCE   2  (bases 1 to 1074)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 1074)
  AUTHORS   Loughran,G., Sachs,M.S., Atkins,J.F. and Ivanov,I.P.
  TITLE     Stringency of start codon selection modulates autoregulation of
            translation initiation factor eIF5
  JOURNAL   Nucleic Acids Res 40 (7), 2898-2906 (2012)
   PUBMED   22156057
REFERENCE   4  (bases 1 to 1074)
  AUTHORS   Ciaudo,C., Bourdet,A., Cohen-Tannoudji,M., Dietz,H.C., Rougeulle,C.
            and Avner,P.
  TITLE     Nuclear mRNA degradation pathway(s) are implicated in Xist
            regulation and X chromosome inactivation
  JOURNAL   PLoS Genet 2 (6), e94 (2006)
   PUBMED   16789828
REFERENCE   5  (bases 1 to 1074)
  AUTHORS   Bohnsack,M.T., Regener,K., Schwappach,B., Saffrich,R.,
            Paraskeva,E., Hartmann,E. and Gorlich,D.
  TITLE     Exp5 exports eEF1A via tRNA from nuclei and synergizes with other
            transport pathways to confine translation to the cytoplasm
  JOURNAL   EMBO J 21 (22), 6205-6215 (2002)
   PUBMED   12426392
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_213456.4, XM_001081454.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212688.1, BC159406.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1074
                     /gene="Eif1"
                     /gene_synonym="Sui1-rs1"
                     /note="eukaryotic translation initiation factor 1"
                     /db_xref="GeneID:287703"
                     /db_xref="RGD:1306308"
     exon            1..178
                     /gene="Eif1"
                     /gene_synonym="Sui1-rs1"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..489
                     /gene="Eif1"
                     /gene_synonym="Sui1-rs1"
                     /note="suppressor of initiator codon mutations, related
                     sequence 1"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 1"
                     /protein_id="NP_001099307.1"
                     /db_xref="GeneID:287703"
                     /db_xref="RGD:1306308"
                     /translation="MSAIQNLHSFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTL
                     TTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGL
                     AKDDQLKVHGF"
     exon            179..342
                     /gene="Eif1"
                     /gene_synonym="Sui1-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            343..444
                     /gene="Eif1"
                     /gene_synonym="Sui1-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            445..1074
                     /gene="Eif1"
                     /gene_synonym="Sui1-rs1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccgccccag tcactgagcc gccgccgagg actcagctgc ctccccctcg agccccctcg
       61 cttcccgacg ctccgtcccc cccgcccgcc ttctcccgca gccgccttcc gcaggccgtt
      121 tccaccgagg aaaaggaatc gtatcgtatg tccgctatcc agaacctcca ctctttcgac
      181 ccctttgctg atgcaagtaa gggtgatgac ctgcttcctg ctggcactga ggattatatc
      241 catataagaa ttcaacagag aaacggcagg aagaccctta caactgtcca agggatcgct
      301 gatgattacg ataaaaagaa actagtgaag gcgtttaaga agaaatttgc ctgcaatggt
      361 actgtaattg agcatccaga atatggagaa gtaattcagc tacagggtga ccagcgcaag
      421 aacatatgcc agttcctgat agagattgga ctggctaagg acgatcagct gaaggttcat
      481 gggttttaag tgcttgtggc tctctgaagc ttaagtgagg atttccttgc aatgagtaga
      541 atttcccttc tgtcccttgt cacaagttta aaaacctcac agcttgtata atgtaatcat
      601 ttggggtccg cttttaactt ggactagtgt aactccttca tgcaataaac tgaaaagagc
      661 catgctgtgt agtcttgaag tccctcattt taaacaggtt aagcagtaag ccctgacagt
      721 ccaccctgga acaaagcaat aaataacagg atttcagcca agccaagaac ccccaaatca
      781 ctggaggcta tgtctgacca gaagttcctt gggactccct tgacacagtc cccagcccta
      841 gaagagtgtc accatttgaa cagcccaggt gactgagagt atgggtaact gccccagcta
      901 tatcattaga gttgagtctc tctggctgta aaaagaaccc ctggtgtctg accaggtagg
      961 cagaatccag aaagggctac ctttccagag aagtcatgga cattagctca ccaccagggc
     1021 agtctttttt aggcagatct ctcctagcca agggatgttg aaacatgaag ggta
//
