LOCUS       NM_001107692            1199 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus ephrin A4 (Efna4), mRNA.
ACCESSION   NM_001107692 XM_001074474 XM_227416
VERSION     NM_001107692.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1199)
  AUTHORS   Xu LJ, Gao F, Cheng S, Zhou ZX, Li F, Miao Y, Niu WR, Yuan F, Sun
            XH and Wang Z.
  TITLE     Activated ephrinA3/EphA4 forward signaling induces retinal ganglion
            cell apoptosis in experimental glaucoma
  JOURNAL   Neuropharmacology 178, 108228 (2020)
   PUBMED   32745487
  REMARK    GeneRIF: Activated ephrinA3/EphA4 forward signaling induces retinal
            ganglion cell apoptosis in experimental glaucoma.
REFERENCE   2  (bases 1 to 1199)
  AUTHORS   Liu XM, Kang HY, Xu JW and Sun DH.
  TITLE     [Inhibitory effect of chondroitinase ABC on ephrin A4 expression
            after spinal cord injury in rats]
  JOURNAL   Sheng Li Xue Bao 63 (6), 498-504 (2011)
   PUBMED   22193443
  REMARK    GeneRIF: Chondroitinase ABC can decrease the expression level of
            EphA4 and reduce the number of astrocytes after spinal cord injury.
REFERENCE   3  (bases 1 to 1199)
  AUTHORS   Aasheim HC, Patzke S, Hjorthaug HS and Finne EF.
  TITLE     Characterization of a novel Eph receptor tyrosine kinase, EphA10,
            expressed in testis
  JOURNAL   Biochim Biophys Acta 1723 (1-3), 1-7 (2005)
   PUBMED   15777695
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473976.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_227416.2, XM_001074474.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV770262.1, SRR8487226.86745.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840109 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1199
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1199
                     /gene="Efna4"
                     /note="ephrin A4"
                     /db_xref="GeneID:310643"
                     /db_xref="RGD:1307808"
     exon            1..174
                     /gene="Efna4"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..676
                     /gene="Efna4"
                     /codon_start=1
                     /product="ephrin-A4 precursor"
                     /protein_id="NP_001101162.1"
                     /db_xref="GeneID:310643"
                     /db_xref="RGD:1307808"
                     /translation="MRLLPLLRTVLWAALLGSRLRGCSSLRHSIYWNSTNPRLLRGDA
                     VVELGLNDYLDIFCPHYESPGPPEGPETFALYIVDWSGYEACKAEGANAFQRWNCTLP
                     FAPFVPVRFSEKIQRFTPFPLGFEFLPGETYYYISVPTPESPGQCLRLQVSVCCKEDR
                     SESAHPVGSPGESGTSGWRGGHAPSPLSLLLLLLLPILRLLRVL"
     exon            175..470
                     /gene="Efna4"
                     /inference="alignment:Splign:2.1.0"
     exon            471..539
                     /gene="Efna4"
                     /inference="alignment:Splign:2.1.0"
     exon            540..1199
                     /gene="Efna4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccgggaca gagaagtggg ccgggaccag ccgggccaga ccagactgga ccccaggggc
       61 gatgcggctg ttgcccctgc tgcggactgt gctctgggcc gcgctgctcg gctcgcgcct
      121 gcgggggtgc tccagcctcc gccactctat ctactggaac tccactaacc ccaggttgct
      181 tcgaggagat gccgtggtgg agctgggcct caacgattac ctagacatct tctgcccaca
      241 ttatgagagc ccagggcccc cagagggccc ggaaacgttt gcattataca tagtggactg
      301 gtcaggctac gaggcctgca aggcagaggg ggcaaatgcc ttccagcgct ggaattgcac
      361 gctacctttt gcgccttttg tccctgttcg attctccgaa aagattcagc gcttcacacc
      421 gttcccgctg ggcttcgagt tcttgcctgg agagacttac tactacatct cggtgccaac
      481 tccggagagt cctggccagt gcctgagact ccaggtgtct gtctgctgca aggaggacag
      541 atccgagtca gctcatcctg tcgggagccc tggagaaagt ggcacatctg ggtggcgggg
      601 aggacacgcc cccagccctc tgtctctcct gctgttgctg ctgctcccaa tactccgtct
      661 tctgcgagtt ctgtgagcca agtacacctt cccagtcacc ccaaggagcc agagcccttc
      721 ccaggatcct ctgttgaagg ggttcctgcc accgtacagg cgatgccaag ccaggcagac
      781 atgatgaagc tttgatgtgc aaagtcggag gatctgaggt gacccttgta ggtgactgct
      841 ccctcactac aggctgaaga ggaactgcaa ggaagctgca gacagtcggg cacccagaag
      901 catagctgct ttgatggtct tgtctcctcc ccctggaaga ctgggatttc aggggatcaa
      961 atccttgaga cactgggggc caaagccaaa gacctgggaa ccggtgggtt cctggccaag
     1021 agcagagaag ccacggtctc tgtggcctcc aggcctcttc ccaggagcaa ttgttgcccc
     1081 ttccagggag ccactctctt gtcttctgtg aagacggact tgccatgagg ttgaatttca
     1141 tgctggtttg tattttttat aaagtgtttg gaccaaacct tcaataaatc acccgttct
//
