LOCUS       NM_001107534            3621 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus elongation factor like GTPase 1 (Efl1), mRNA.
ACCESSION   NM_001107534 XM_001062690 XM_001062746 XM_218845
VERSION     NM_001107534.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3621)
  AUTHORS   Finch,A.J., Hilcenko,C., Basse,N., Drynan,L.F., Goyenechea,B.,
            Menne,T.F., Gonzalez Fernandez,A., Simpson,P., D'Santos,C.S.,
            Arends,M.J., Donadieu,J., Bellanne-Chantelot,C., Costanzo,M.,
            Boone,C., McKenzie,A.N., Freund,S.M. and Warren,A.J.
  TITLE     Uncoupling of GTP hydrolysis from eIF6 release on the ribosome
            causes Shwachman-Diamond syndrome
  JOURNAL   Genes Dev 25 (9), 917-929 (2011)
   PUBMED   21536732
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473980.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_218845.4, XM_001062690.1, XM_001062746.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132275,
                              SAMD00132291 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3621
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..3621
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /note="elongation factor like GTPase 1"
                     /db_xref="GeneID:308789"
                     /db_xref="RGD:1306521"
     exon            1..53
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            54..159
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..3452
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /note="elongation factor Tu GTP-binding domain-containing
                     protein 1; elongation factor Tu GTP binding domain
                     containing 1"
                     /codon_start=1
                     /product="elongation factor-like GTPase 1"
                     /protein_id="NP_001101004.1"
                     /db_xref="GeneID:308789"
                     /db_xref="RGD:1306521"
                     /translation="MVLSGLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNG
                     IISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAEGSEEYLINLIDSPGHVDFSSE
                     VSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQ
                     EAYSHLKNILGQINALTGTLFTSKVLEERAERETESQAKSHSEQGDQVYDWSTGLEDV
                     DDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMK
                     AKKIMKVDQAKGKKPLFVQLILENIWSLYDAVLKKDKEKVDKIVTSLGLKIGAREARH
                     SDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDMTSERVEKLMCTGSQTFESLPLET
                     QALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHA
                     EKLAAAQGQAPQGPTQDGGALETSPQEDEPRGEEPDMTSVSRQPAPQEESSQEAFIAF
                     ARVFSGVARRGKKIFVLGPKYSPVDFLQRVPQGFSAPLEDLPPVPHMACCTLENLYLL
                     MGRELEDLEEVPPGNVLGIGGLQDSVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEP
                     KHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLRERFAKIH
                     ISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGILVDSDGLI
                     TIPTPNKLATLSVRAIPLPEEVTRILEENSDLIRSMELLTSSLNEGRNTQAIHQKTQE
                     KIWEFKGKLEKHLTGRKWRNTVDQIWSFGPRKCGPNILVSRSEDFQSSVWSGPAGRES
                     KEASRFRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEPGASDKQSQG
                     QCDLTGEGQEKSKTCPVGDENQEQQDGYSEPFEETSQKGDSPVIDCYGPFSGQLIATM
                     KEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFI
                     IKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKA
                     DSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK"
     exon            160..227
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            228..312
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            313..446
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            447..584
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            585..799
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            800..923
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1000
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1137
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1260
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1261..1360
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1512
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1679
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1818
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1819..1950
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            1951..2098
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            2099..3078
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            3079..3263
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
     exon            3264..3621
                     /gene="Efl1"
                     /gene_synonym="Eftud1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgagctac tcctgagcct tagaagcata agtgaggtgc ggcgtggagc cggtcacagg
       61 aaataaccat ggtgctcagt ggtcttgata agatgattca acttcagaag aacactgcca
      121 acattaggaa tatctgtgtt ttggctcatg ttgaccacgg aaaaactacc cttgctgatt
      181 gtcttatatc cagtaatgga atcatctcca gccgtctggc aggcaagtta aggtacatgg
      241 acagcagaga agatgaacag gtcagaggga tcaccatgaa gtccagcgcc atttcactac
      301 attatgcaga aggtagtgag gagtacctga ttaatctgat agactctcct ggacatgtgg
      361 acttctcctc agaagtctcg accgcggttc gcatttgtga cggatgcatt atagtggtgg
      421 atgctgtgga gggcgtctgt ccacagacac aggcagttct tcgacaagcc tggcttgaaa
      481 acatccgccc tgttttagtg attaataaga tagaccgcct gatagtggaa ctgaaattca
      541 ccccacaaga ggcctattct cacctcaaga atattttagg acagattaac gcacttacag
      601 gaactctttt tacttctaaa gtcctagaag aaagagcaga gagagagaca gaatcccagg
      661 cgaagtcaca ttctgaacaa ggagatcaag tgtacgactg gagcacaggc ttggaggatg
      721 tggacgactc tcagctgtac ttctccccag agcagggcaa tgtggtgttc accagtgcaa
      781 tagatggctg gggctttgga attgagcact tcgccagaat ctatagtcaa aaaattggca
      841 tcaagaagga agttcttttg aaaaccttgt ggggagatta ttacataaat atgaaggcta
      901 aaaagattat gaaagttgat caggccaaag gaaagaaacc tttatttgta cagttgatcc
      961 tggaaaatat atggagtttg tatgacgcgg tcttgaaaaa agacaaagaa aaagttgata
     1021 aaattgtgac ttctttggga ttaaaaattg gagcccggga ggcacgacat tcagacccta
     1081 aagtccagat caatgccatt tgcagccagt ggcttcccat ctcccacgcg gtcctcgcta
     1141 tggtgtgtca gaaactgccc agtccccttg acatgacatc tgagcgagtg gagaaactga
     1201 tgtgcacagg atcacagacg tttgagtctc tccccctgga aacccaagcc ctgaaagcag
     1261 cttttatgaa atgtggaagt gaggatactg ctccggttat tatcttcgtt tccaaaatgt
     1321 ttgcagttga tgtgaaagcc ttgcctcaga ataagccaag gcctctcact caagaagaaa
     1381 tggcccagag acgtgaacgt gcaagacaaa ggcatgcaga aaagcttgca gcagcacagg
     1441 ggcaagcacc ccagggaccc acccaggatg gaggtgccct tgaaacaagt ccccaggaag
     1501 atgagccaag aggtgaggaa ccagatatga caagtgtaag ccgtcaacct gcaccccagg
     1561 aagagagcag ccaagaggcc tttattgcat ttgctcgtgt gttcagtggt gtagctcgaa
     1621 gaggaaagaa aattttcgtc ttgggaccta agtacagtcc tgttgatttt ttacagcggg
     1681 ttccacaagg cttctcagct ccactagagg acctccctcc tgtgccccac atggcatgct
     1741 gtactttgga gaacctgtat cttctgatgg gaagggagct ggaagatttg gaggaagtcc
     1801 ccccaggaaa cgtgctggga attggaggcc tccaggactc tgtgttgaaa tctgcgactc
     1861 tgtgcagcct gccctcttgc ccgccgttca tccccctcaa cttcgaagcc acccctattg
     1921 tgagagttgc tgttgaacca aaacatccaa gtgaaatgcc tcagctcgtg aaaggaatga
     1981 agctgctaaa ccaagctgat ccctgtgtcc agattttaat tcaagaaaca ggagagcatg
     2041 ttttggtcac agccggggag gtccaccttc agcgatgttt ggatgactta agagaaaggt
     2101 ttgcaaagat tcacatcagt gtatctgaac ccattattcc tttcagagag acgatcacaa
     2161 aacctcccaa agttgacatg gtcaatgaag aaataggcag gcaacaaaaa gttgctgtca
     2221 tacaccaaac aaaagaagag caaagcaaaa tcccagaggg gatcctcgtg gactctgatg
     2281 ggcttatcac cataccaaca cccaataaac tggccacact cagcgtccgt gccataccac
     2341 ttccagaaga agtcactcgg attctggaag aaaacagcga cttgattcgt tccatggagc
     2401 ttttaacatc ctccttgaat gagggtagaa atactcaggc cattcatcag aagacccaag
     2461 agaaaatctg ggaattcaaa ggaaaactag agaaacactt aacagggagg aaatggagga
     2521 acactgttga ccaaatctgg tcatttggcc ccagaaaatg tggacccaac atcctagtca
     2581 gtagaagtga agatttccag agctccgtgt ggtctggccc agctggcaga gaatcaaaag
     2641 aagccagtag attccgagac ttcggcaata gcattgtgag cggcttccag ctagcgactc
     2701 tctctggccc catgtgtgag gagcccctca tgggtgtctg tttcgtccta gaaaagtggg
     2761 agctaaataa atgtgcagaa ccaggagcaa gtgataaaca gagccaaggt cagtgtgatc
     2821 tgacaggaga gggacaggag aaaagtaaaa cctgtcccgt tggagatgaa aaccaagagc
     2881 aacaagatgg ctactcagag ccctttgaag agacttccca gaaaggagac tctccagtca
     2941 tagactgcta tggacccttc tctgggcagc taattgccac catgaaagaa gcatgccgct
     3001 atgctctgca ggtgaagcct caacggctga tggcagcgat gtacacatgt gatatcatgg
     3061 ccaccagtga cgtcctcggc cgagtctatg ccgtgctatc aaagcgagaa ggccgagtgc
     3121 ttcaggaaga aatgaaggag gggacggaca tgttcatcat caaggctgtg ctgcctgtgg
     3181 cggagagctt cggcttcgcg gatgaaatca ggaagaggac cagcgggctg gctagccccc
     3241 agcttgtatt cagccactgg gaggtcattc ccagtgaccc attctgggtg ccaaccactg
     3301 aggaggagta cctgcacttt ggggagaagg cagattctga gaaccaggcc cgaaagtaca
     3361 tgaatgcagt gcggaagcgg aagggcctct atgtggaaga aaagatcgtg gaacatgcag
     3421 aaaagcagag aaccctcagc aaaaacaagt agctaagagg aagcagctac tgctagtggt
     3481 ggggcctttt ctaatgaatt aacaagtatt atcaagggtc taatctggga aaatctcatt
     3541 ttggtaaatt atctgtgtgg attcactttc aataataaat atggtctata tattttaaag
     3601 atgtcagaga acatactttc a
//
