LOCUS       NM_001014088            2291 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus endonuclease/exonuclease/phosphatase family
            domain containing 1 (Eepd1), mRNA.
ACCESSION   NM_001014088 XM_235947
VERSION     NM_001014088.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2291)
  AUTHORS   Nelson,J.K., Koenis,D.S., Scheij,S., Cook,E.C., Moeton,M.,
            Santos,A., Lobaccaro,J.A., Baron,S. and Zelcer,N.
  TITLE     EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates
            ABCA1 Abundance and Cholesterol Efflux
  JOURNAL   Arterioscler Thromb Vasc Biol 37 (3), 423-432 (2017)
   PUBMED   28082258
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083816.1.
            
            [WARNING] On Apr 29, 2024 this sequence was replaced by
            NM_001014088.4.
            
            On Jun 3, 2007 this sequence version replaced NM_001014088.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083816.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2291
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..2291
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /note="endonuclease/exonuclease/phosphatase family domain
                     containing 1"
                     /db_xref="GeneID:315500"
                     /db_xref="RGD:1307401"
     exon            1..928
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..1760
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /codon_start=1
                     /product="endonuclease/exonuclease/phosphatase family
                     domain-containing protein 1"
                     /protein_id="NP_001014110.1"
                     /db_xref="GeneID:315500"
                     /db_xref="RGD:1307401"
                     /translation="MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINT
                     ATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSS
                     KGNSAQHSPSSLRRDLLAEQQPHHLATTVPLTPRVNINTATLAQLMSVRGLSEKMAVS
                     IVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPH
                     PSPTSLSLQSEDLDLPPGGPTQIISMRPSVEAFGGMRDGRPVFRLATWNLQGCSVEKA
                     NNPGVREVVCMTLLENSIKLLAVQELLDKEALEKFCTELNQPILPNIRKWKGPRGCWR
                     SIVAEKPSSQLQKGPCYSGFLWDTAANVELRDIPGQESSPSNGHAKTVGPSPFLARFK
                     VGSNDLTLVNLQLTALALPGVENSSKNHSDGHRLLNFALTLQETLKGEKDVVILGDFG
                     QGPDSSDYDILRREKFHHLIPAHTFTNISTRNPQGSKSVDNIWISKSLKKVFTGHWAV
                     VREGLTNPWIPDNWSWGGVASEHCPVLAELYMEKDWSKKEVPRNGNGVTLEPSEANVK
                     HER"
     exon            929..980
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1091
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1226
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1365
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1560
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..2258
                     /gene="Eepd1"
                     /gene_synonym="RGD1307401"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaggctcccg ggttccttct ctatccagaa ttgttttgtg gtggttggcc atggggagca
       61 ccctgggctg ccatcgctct atccccagag acccatcaga cctgtcacat agccgcaagt
      121 tcagcgctgc ctgcaacttc agcaacatcc tggtgaatca ggagcgacta aatatcaaca
      181 ctgccactga ggaggaactg atgaccctgc ctggggtgac acgtgcagtg gcccgaagca
      241 tcgtggagta ccgagaatat atcggcggct tcaagaaggt ggaagatcta gcacttgtca
      301 gtggtgtagg ggccactaaa ctagaacagg tcaagtttga gatctgtgtg agcagcaagg
      361 gtaactcagc acagcactct cccagttccc tgaggcggga tctgctggct gagcagcagc
      421 cccatcacct ggccaccact gtgcccctca ctccacgagt caatatcaac acagccaccc
      481 ttgctcagct catgagtgtc cggggcctca gtgagaagat ggccgtcagc atcgtggact
      541 accgccgcga acatggccct ttccgaagtg ttgaggactt ggtgaggatg gatggaatca
      601 atgcagcctt cctggacaga atacgacacc aggtgttcgc agagaggtcc aggcccccat
      661 ctacccacac caatgggggt cttaccttca ctgccaagcc tcatcccagt cccacgtctc
      721 tgagcctgca gagtgaggac ttggacctgc caccaggggg gcccacgcag attatctcta
      781 tgaggccctc ggtggaggcc tttggaggta tgagggatgg gcgacctgtg tttaggttgg
      841 ccacgtggaa cttacagggc tgctctgtgg agaaggccaa taacccaggg gtccgagagg
      901 tggtgtgcat gacgcttctg gaaaacagca tcaaacttct agctgtgcaa gaactgcttg
      961 acaaagaagc cctggaaaag ttctgtacag agctgaacca gccaatcctg cccaacatcc
     1021 gcaagtggaa gggcccccgg ggatgctgga ggtccattgt tgctgagaag ccttccagtc
     1081 agctccagaa gggcccctgc tactctggat tcctgtggga cacagcagcc aatgtggagc
     1141 tgagagacat ccccgggcag gagagctcac ccagcaacgg tcatgcgaag actgtgggtc
     1201 ccagcccgtt cctcgccagg ttcaaggtgg gaagtaatga cttgaccctg gttaacctcc
     1261 agctgacagc cctggccctc ccaggagttg agaattccag caagaatcac agcgatggcc
     1321 accgattatt gaattttgca ctaaccctcc aggaaaccct gaaaggagaa aaagatgttg
     1381 ttattttagg ggattttggc caagggccag atagcagtga ctatgatatc ctaaggagag
     1441 aaaaatttca ccacctgatc ccggctcata ccttcaccaa catcagcacc aggaatcctc
     1501 aaggctccaa atccgtggac aacatctgga tcagcaaaag cttaaagaaa gtgttcacgg
     1561 gtcactgggc tgttgtgaga gaaggcctca caaacccttg gattccagat aactggtcct
     1621 ggggtggagt cgcttccgaa cattgccctg tgcttgctga attgtacatg gaaaaggact
     1681 ggagcaagaa ggaagtcccc aggaatggca atggagtcac cttagagcca agcgaagcca
     1741 acgtcaaaca tgagcggtga tgacatcact ctttctggcc tctgactcag gagagcatag
     1801 gaaggagctg gcactacagg gtgggaagat ccagggcctg tgaagcatca ttctgaggac
     1861 ctacgtcttg gtccctgcac cactgtctac tttgtgaaca cttgagaacc tctcctgagg
     1921 ggagcccgtc aggcgctggc tctgttgggc atcacggcga agctggctgg gactgcaatg
     1981 tcttgacgct gtgtggctga gttcaggctt ggggcggggg ctatactgct ggccgagttg
     2041 tttagcagca tgagaacagt gacagagcag tgaagtggag atgggaaaga ggactcaggc
     2101 tggcgatcca cgccacggct ctcatttctg cctcaccacg atgtcatgtt ctgccgacaa
     2161 acttcaggaa gcttttaact gtgatgaatg cacttctcaa agatttttag ttttgttttg
     2221 aaaaaggaaa agaataataa acagattaat ctgcctggaa aaaaaaaaaa aaaaaaaaaa
     2281 aaaaaaaaaa a
//
