LOCUS       NM_175838               1730 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus eukaryotic translation elongation factor 1 alpha
            1 (Eef1a1), mRNA.
ACCESSION   NM_175838 NM_033539 XM_215242
VERSION     NM_175838.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1730)
  AUTHORS   Boratko,A., Peter,M., Thalwieser,Z., Kovacs,E. and Csortos,C.
  TITLE     Elongation factor-1A1 is a novel substrate of the protein
            phosphatase 1-TIMAP complex
  JOURNAL   Int J Biochem Cell Biol 69, 105-113 (2015)
   PUBMED   26497934
REFERENCE   2  (bases 1 to 1730)
  AUTHORS   Achenbach,J. and Nierhaus,K.H.
  TITLE     The mechanics of ribosomal translocation
  JOURNAL   Biochimie 114, 80-89 (2015)
   PUBMED   25514765
  REMARK    Review article
REFERENCE   3  (bases 1 to 1730)
  AUTHORS   Xilouri,M. and Stefanis,L.
  TITLE     Chaperone mediated autophagy to the rescue: A new-fangled target
            for the treatment of neurodegenerative diseases
  JOURNAL   Mol Cell Neurosci 66 (Pt A), 29-36 (2015)
   PUBMED   25724482
  REMARK    Review article
REFERENCE   4  (bases 1 to 1730)
  AUTHORS   Parra-Torres,N.M., Cazares-Raga,F.E. and Kouri,J.B.
  TITLE     Proteomic analysis of rat cartilage: the identification of
            differentially expressed proteins in the early stages of
            osteoarthritis
  JOURNAL   Proteome Sci 12 (1), 55 (2014)
   PUBMED   25435813
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1730)
  AUTHORS   Cuervo,A.M. and Wong,E.
  TITLE     Chaperone-mediated autophagy: roles in disease and aging
  JOURNAL   Cell Res 24 (1), 92-104 (2014)
   PUBMED   24281265
  REMARK    Review article
REFERENCE   6  (bases 1 to 1730)
  AUTHORS   Lee,S., Ann,D.K. and Wang,E.
  TITLE     Cloning of human and mouse brain cDNAs coding for S1, the second
            member of the mammalian elongation factor-1 alpha gene family:
            analysis of a possible evolutionary pathway
  JOURNAL   Biochem Biophys Res Commun 203 (3), 1371-1377 (1994)
   PUBMED   7945283
REFERENCE   7  (bases 1 to 1730)
  AUTHORS   Shirasawa,T., Sakamoto,K., Akashi,T., Takahashi,H. and Kawashima,A.
  TITLE     Nucleotide sequence of rat elongation factor-1 alpha cDNA
  JOURNAL   Nucleic Acids Res 20 (4), 909 (1992)
   PUBMED   1542580
REFERENCE   8  (bases 1 to 1730)
  AUTHORS   Ann,D.K., Lin,H.H., Lee,S., Tu,Z.J. and Wang,E.
  TITLE     Characterization of the statin-like S1 and rat elongation factor 1
            alpha as two distinctly expressed messages in rat
  JOURNAL   J Biol Chem 267 (2), 699-702 (1992)
   PUBMED   1730661
REFERENCE   9  (bases 1 to 1730)
  AUTHORS   Taniguchi,S., Miyamoto,S., Sadano,H. and Kobayashi,H.
  TITLE     Rat elongation factor 1 alpha: sequence of cDNA from a highly
            metastatic fos-transferred cell line
  JOURNAL   Nucleic Acids Res 19 (24), 6949 (1991)
   PUBMED   1762922
REFERENCE   10 (bases 1 to 1730)
  AUTHORS   Ann,D.K., Moutsatsos,I.K., Nakamura,T., Lin,H.H., Mao,P.L.,
            Lee,M.J., Chin,S., Liem,R.K. and Wang,E.
  TITLE     Isolation and characterization of the rat chromosomal gene for a
            polypeptide (pS1) antigenically related to statin
  JOURNAL   J Biol Chem 266 (16), 10429-10437 (1991)
   PUBMED   1709933
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2020 this sequence version replaced NM_175838.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X61043.1, BC091297.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840105, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                JAXUCZ010000008.1  88225038-88225069   c
            33-210              JAXUCZ010000008.1  88223928-88224105   c
            211-390             JAXUCZ010000008.1  88223659-88223838   c
            391-687             JAXUCZ010000008.1  88223270-88223566   c
            688-838             JAXUCZ010000008.1  88223041-88223191   c
            839-1095            JAXUCZ010000008.1  88222673-88222929   c
            1096-1330           JAXUCZ010000008.1  88222349-88222583   c
            1331-1730           JAXUCZ010000008.1  88221847-88222246   c
FEATURES             Location/Qualifiers
     source          1..1730
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..1730
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /note="eukaryotic translation elongation factor 1 alpha 1"
                     /db_xref="GeneID:171361"
                     /db_xref="RGD:67387"
     exon            1..32
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
     exon            33..210
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1455
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /note="eukaryotic translation elongation factor 1 alpha 2
                     like 1; EF-1 alpha2; EF-Tu; eEF1A-1; EF-1-alpha-1;
                     elongation factor Tu; elongation factor 1 A-1; eukaryotic
                     elongation factor 1 A-1"
                     /codon_start=1
                     /product="elongation factor 1-alpha 1"
                     /protein_id="NP_787032.1"
                     /db_xref="GeneID:171361"
                     /db_xref="RGD:67387"
                     /translation="MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEK
                     EAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNM
                     ITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEP
                     PYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTR
                     KDGSASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGM
                     VVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPP
                     MEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPK
                     FLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGK
                     VTKSAQKAQKAK"
     exon            211..390
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
     exon            391..687
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
     exon            688..838
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
     exon            839..1095
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1330
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1730
                     /gene="Eef1a1"
                     /gene_synonym="EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; SI"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttttcgcaa cgggtttgcc gtcagaacgc aggtgttgtg aaagccaccg ctaattcaaa
       61 gcaaaaatgg gaaaggaaaa gactcacatc aacatcgtcg taattggaca cgtagattcc
      121 ggcaagtcca ccacaaccgg ccacctgatc tacaaatgtg gtggaatcga caaaagaacc
      181 attgaaaagt ttgagaagga ggctgcggag atgggaaaag gctccttcaa gtatgcctgg
      241 gtcctggaca aactgaaagc tgagcgtgag cgtggtatca ctattgacat ctccctgtgg
      301 aagtttgaga ccagcaagta ctatgtgact atcattgatg ccccaggaca cagagacttc
      361 atcaagaaca tgattacggg cacatctcag gctgactgcg ctgtcctgat tgttgctgct
      421 ggtgttgggg aatttgaagc tggtatctcc aagaacgggc agacccgtga gcatgctctt
      481 ctggcttaca ctttgggtgt gaaacagcta attgttggtg tcaacaaaat ggattccacc
      541 gagccaccat acagtcagaa gagatacgag gaaatcgtta aggaagtcag cacctacatt
      601 aagaaaattg gctacaaccc tgacacagta gcatttgtgc caatttctgg ttggaatggt
      661 gacaacatgc tggagccaag tgctaatatg ccgtggttca agggatggaa agtcacccgc
      721 aaagatggca gtgccagtgg caccacgctg ctggaagctt tggactgcat tctgccgcca
      781 actcgtccaa ctgacaagcc tctgcgactg cccctccagg atgtctataa aattggcggc
      841 attggcactg tccctgtggg ccgagtggaa actggtgttc tcaaacctgg tatggtggtt
      901 acctttgctc cagtcaatgt aacaactgaa gtcaagtctg tggaaatgca ccatgaagct
      961 ttgagtgaag ctctgcctgg ggacaatgta ggcttcaacg taaagaacgt gtctgtcaaa
     1021 gacgttagac gtggcaatgt tgctggggac agcaaaaatg acccaccaat ggaagcagct
     1081 ggcttcactg ctcaggtgat tatcctgaac catccaggcc agatcagtgc tggctatgcc
     1141 cctgttctgg actgccacac ggcccacata gcatgcaagt ttgccgagct taaagagaag
     1201 atcgatcgtc gttctggtaa gaagctggaa gatggcccca aattcttgaa gtctggtgat
     1261 gctgccattg ttgacatggt ccctggcaag cccatgtgtg ttgaaagctt ctctgactac
     1321 cctccacttg gtcgttttgc tgttcgtgac atgaggcaga cagttgctgt gggtgtcatc
     1381 aaagccgtgg acaagaaggc tgcaggagct ggcaaagtca ccaagtctgc ccagaaagct
     1441 cagaaggcta aatgaatatt atccctaaca cctgccaccc cagtcttaat cagtggtgga
     1501 agaacggtct cagaactgtt tgtctcaatt ggccatttaa gtttaatagt aaaagactgg
     1561 ttaatgataa caatgcatcg taaaaccttc agaaggaaag aatgttttgt ggaccatttt
     1621 tttttgtgtg tggcagtttt aagttattag ttttcaaaat cagtactttt taatggaaac
     1681 aacttgacca aaaatctgtc acagaatttt gagaccatta aaacaagttt
//
