LOCUS       NM_001107557            5203 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus erythroid differentiation regulatory factor 1
            (Edrf1), mRNA.
ACCESSION   NM_001107557 XM_001054788 XM_219414
VERSION     NM_001107557.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5203)
  AUTHORS   Wang,D., Li,Y. and Shen,B.
  TITLE     A novel erythroid differentiation related gene EDRF1 upregulating
            globin gene expression in HEL cells
  JOURNAL   Chin Med J (Engl) 115 (11), 1701-1705 (2002)
   PUBMED   12609092
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001054788.1, XM_219414.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132279,
                              SAMD00132298 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..5203
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..5203
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /note="erythroid differentiation regulatory factor 1"
                     /db_xref="GeneID:309069"
                     /db_xref="RGD:1306820"
     exon            1..232
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..3748
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /codon_start=1
                     /product="erythroid differentiation-related factor 1"
                     /protein_id="NP_001101027.1"
                     /db_xref="GeneID:309069"
                     /db_xref="RGD:1306820"
                     /translation="MMGDPKEAGAEASPSGAAARGGLSLLSQTESEEPSAQGSALFLG
                     GNEVKSRAVVKYSSAPPRTAFARLEEKTDLKLPPANWLRESAKLGPAGTTILGNSKKS
                     KPFSSFGMAYDFIDSVGNDVDVVSDSENIKKLLKIPYSKSHVSMAVHRIGRTLLLDEL
                     DIQELFMRSSQTGDWTWLKEFYQRLIDQKWQRKKKSKEHWYQKAILSKFLYYSINGDG
                     AAQPVPSPAEQQESASSDQTHESEGASWPAPFEMPSSVSEDPSASSQGLKNDFVRNIL
                     WTFEDIHMLVGSNMPIFGGGRYPAVSLRLRDNNKPINVLTGIDYWLDNLICNVPELVM
                     CFHVNGIVQKYEMIKTEEIPNLENSNFSTKVIKDIAQNILSFLKSNCTKEGHTYWLFK
                     ASSSDIVKLYDLTTLCEETEDKYQNPFTMPVAILLYKVACNMMMKKNQNKKHYGTIRT
                     LLLNCVKLLDKSRHPQIIASANYMLSELFQLDEPKKEESSDSPLNENSDESYSEEEEE
                     EEMADSDENGSYGTSSDPADDNKAVAIIKSVGELSVPEKYKSIHQIRPSCAFPVCHDT
                     EERCRLVLSYVLEGLKSVDSSIKKESDLPAADPSTPIPLKYEDESTRGGPEGLEKQMA
                     LFLDKMGSLQKGNCSGQSGMTPGSWQHKMKLQLILKSSKAYYILSDAAMSLQKYGRAL
                     RYIKLALQSHDTYCCLCTNMLSEVLLFLSQYLTLCGDIQLMLAQNANNRAAHLEEFNY
                     QTKEDQEILHSLHRESSCQGFAWATDLSTDLESQLSVSCKCYEAANEILQFSDLKSQN
                     PEHYVQVLKRMGNIRNEIGVFYMNQAAALQGERVVSKSVSAAEQQLWKKSFSCFEKGI
                     HNFESIDDATNAALLLCNTGRLMRVCAQAHCGAEDEFKREFSPEEGLYYSKAVDYYLK
                     ALRSLGTRDMHPVVWDSVNWELSTTYFTMATLQQDYAPLSRKAQEQIEKEVSEAMMKS
                     LKHCDVDSATARQPLCQYRAATIHHRLASMYHSCLRNQVGDEHLRKQHRVLADLHYSK
                     AAKLFQLLKDAPCELLRVQLERVAFAEFQMSSQNSNVGKLKTLSGALDIMVRTEHAFQ
                     LIRKELVEECDQPKNDEATPAADSSPNLNREEVIKLLSIFESRLSFLLLQSIKLMSSS
                     KRKMSSNTEDDAALQTNKQIYSQLLRATANRNSTLLERIEVVICLLEQLASGSSGSSG
                     SAVP"
     exon            233..441
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            442..508
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            509..634
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            635..759
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            760..916
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1038
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1150
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1298
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1407
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1519
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            1520..1786
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1858
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            1859..2009
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2198
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2399
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            2400..2618
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2842
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            2843..3001
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            3002..3151
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            3152..3305
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            3306..3421
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            3422..3573
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
     exon            3574..5203
                     /gene="Edrf1"
                     /gene_synonym="RGD1306820"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaagtgcg aggcgcagag cgtccgagtc tctcgctctg aggttctcct gcggctctgg
       61 gcccgcgttc ctgtcgccga ctccaggtct cgcgcgtctg gtctcctccc cagggtcgga
      121 aatgatgggg gaccccaagg aagcaggagc cgaggcttct ccatcagggg cggccgcccg
      181 aggagggctc agcctcctat cccagacgga atccgaggag ccttctgcac aggggtcagc
      241 cttatttctt ggaggcaatg aagtgaaaag ccgagctgtg gtgaaatact cttctgcccc
      301 tcctcgaaca gcatttgcac gtctcgaaga aaaaacagac ttgaaactcc cacctgccaa
      361 ctggttacga gagagtgcca aactagggcc ggcaggaact accattcttg gcaatagtaa
      421 gaaaagcaag ccgttttcga gtttcggcat ggcatatgac ttcattgact cggtgggaaa
      481 tgatgtggat gttgtctctg actcggaaaa cataaaaaag ctcctgaaga ttccctacag
      541 caagtctcat gtaagcatgg ctgtccaccg cataggaagg accctcttat tagatgaact
      601 ggatattcaa gaactcttta tgaggtcatc tcagactggt gattggacat ggttgaaaga
      661 gttctatcaa agactgattg atcagaagtg gcagaggaaa aagaaaagca aggagcactg
      721 gtatcagaag gctattcttt ccaagttctt gtactacagc atcaacggtg atggagctgc
      781 tcagcctgtt ccatctcctg cagaacaaca agagtcagct agttctgatc agacacatga
      841 gtctgaaggg gcttcctggc ctgctccctt tgaaatgccg tcgtcagttt ctgaagatcc
      901 cagtgcttcc agtcagggtc ttaaaaatga ttttgtccgg aatattctgt ggacttttga
      961 agatatccat atgctagttg gttctaacat gcctatattt ggtggaggca gatatccagc
     1021 agttagccta cgtctcaggg ataacaacaa accaattaat gtgttgactg gaattgacta
     1081 ttggttggac aacttgatat gcaatgtacc agaacttgtg atgtgcttcc atgtaaatgg
     1141 gattgtacag aaatatgaga tgataaagac agaagaaatc cccaatttgg aaaactctaa
     1201 tttttctact aaagttataa aagacattgc acagaatatt ttatcgtttc ttaaatctaa
     1261 ttgtaccaaa gaagggcata cctactggct ctttaaagca agcagcagtg atattgtgaa
     1321 gctctatgac ctcacgactc tgtgtgaaga aactgaagac aagtaccaga atccattcac
     1381 aatgccagtg gctatcctct tatacaaggt ggcttgtaac atgatgatga agaaaaatca
     1441 aaacaagaag cactatggaa ctattagaac attacttctc aactgtgtta agttgttgga
     1501 caaaagcaga catcctcaaa ttattgcttc agccaactac atgctttcag agcttttcca
     1561 gttggatgag cctaaaaagg aagaaagttc agactcccct ttaaatgaga attcagatga
     1621 aagctacagt gaggaggagg aggaggagga gatggcggac agtgatgaga atggctccta
     1681 cggtaccagc tctgacccag cagacgataa caaggcagtg gctataatta aatctgttgg
     1741 agaactgtca gtaccagaaa aatacaagtc aattcatcag atcagaccca gttgtgcatt
     1801 tcccgtttgc catgacacgg aagagcgctg tcgactcgta ctaagctatg tgttggaggg
     1861 tttaaaatct gtagatagta gcatcaaaaa agaaagtgac ctcccagcag ctgaccccag
     1921 cactcctatc cccttaaaat atgaagatga atccacaagg ggtggtcctg aggggctgga
     1981 gaagcagatg gccttgttcc tggacaaaat gggctccctt cagaagggca attgttctgg
     2041 gcagtctgga atgacccctg gttcttggca acataaaatg aaacttcagc taattctcaa
     2101 gtcatcaaaa gcctactaca ttttgtcaga tgctgccatg agtcttcaga agtatggaag
     2161 agcgttgaga tacattaagc tagctctgca gagccatgat acttactgct gcctctgcac
     2221 caacatgctc tctgaagtgc tgctgtttct ctctcaatac ctgaccctct gtggtgacat
     2281 ccagctcatg ctggcccaga acgcaaacaa cagagcagca caccttgagg aatttaatta
     2341 ccaaacaaaa gaagaccagg agatcctcca cagtctccac agagagtcca gctgccaggg
     2401 atttgcatgg gcaacagatc tatctacaga cttagaaagt caactttcag ttagttgtaa
     2461 atgttatgag gctgctaatg aaatcttgca atttagtgac ttaaaaagtc agaatccaga
     2521 gcactacgta caagtgttga agagaatggg aaacattaga aatgaaatcg gtgtattcta
     2581 catgaatcag gctgctgcgc tgcagggtga gcgagtagtg agcaaatctg tgtctgctgc
     2641 agagcaacaa ttgtggaaaa aaagcttttc ttgttttgaa aaggggattc acaactttga
     2701 gtcgattgat gatgctacaa atgctgccct cctgctgtgc aacacaggaa gactcatgcg
     2761 ggtctgtgca caggcgcact gtggtgcaga ggatgagttc aaacgggagt tctccccaga
     2821 agagggcttg tattacagca aggccgttga ttactatttg aaggctctga ggtcgctggg
     2881 aacgagagac atgcacccag ttgtttggga ttctgtgaac tgggaattgt cgactacata
     2941 cttcaccatg gcgactctac agcaagatta tgctccatta tccagaaaag ctcaggagca
     3001 gattgagaaa gaagtcagtg aggctatgat gaagtccctg aagcactgcg atgttgactc
     3061 agcaactgct cggcagcccc tctgtcagta ccgcgctgca accatccatc acaggctggc
     3121 ttccatgtac cacagctgtc tgaggaacca ggttggtgat gagcatctta ggaagcagca
     3181 ccgagtgctg gcagatctcc actacagcaa agctgcaaag ctctttcaac ttctcaaaga
     3241 tgctccttgt gaactgctta gagtgcagtt agaaagggtg gcatttgcag aatttcagat
     3301 gagcagtcag aatagcaatg ttggaaagtt aaaaacatta tctggggcac ttgatatcat
     3361 ggtgagaact gagcatgctt tccagctcat tcggaaggag cttgtagagg aatgtgacca
     3421 gcctaagaat gatgaagcta caccggctgc tgattcttca cctaatctta atcgagaaga
     3481 agtgatcaaa ctccttagta tatttgaatc tcgcctgtca ttccttctcc ttcaatccat
     3541 caaactgatg tcatcatcta aaaggaaaat gagcagtaac acggaagatg atgcagccct
     3601 ccagaccaac aagcagattt actcccagct tttgagagca actgccaaca gaaactccac
     3661 tctgttggag agaattgaag ttgtcatctg tctgctggag cagcttgcat ctggtagcag
     3721 tggatcgagt ggcagtgctg tcccctgacc tgaagttgtc tcggaggact gtcttgtcag
     3781 tgccttccca tcctggagct gttctgtcca ctcggtgctg agacttatta aatataagga
     3841 gatgccattt aatcaggtcc acagtgggta ctcgcttccc gtggcaggca gaggatgtgg
     3901 ggtggtttgg tttcttcctg taaaggtgag aaaccataat ggaatcaaaa gctttctgaa
     3961 tgtatttcct cgagaagtac ttggttcctt agtgataaca gacctcctgt gatgtgctta
     4021 gacttggaga tattcttgaa ggatattaaa acacttggac ataagatgag attattttag
     4081 ataaaatgtt actctggcca agagaactct tattcaagtg atttcacgtt caaatggcgt
     4141 gtagaaacag tacacatctg tgtttccttg tgagtgacag aagtgtaccc tttccaaact
     4201 gttgcacagg aggtttcgaa gactgaaagt tgtgcaggtc tcctttcagt gcatgttctg
     4261 aaaggcctca cttttctttg actgtatgtg acattgataa agactaggta ctatcacttt
     4321 ctcattttaa acttgaaact gtgaataagg taagagaact attttgaata aataagctat
     4381 ttatttaaaa taccttggta gttcccactt gcattcttca cactgctgtg atttgatctg
     4441 cttgcttatg atttcaaaac tttacaaagt acatagatcc taatgttcag ggcaaaggtc
     4501 tctcacacat tcatgctcct tgaacattct gctgtgcctt gctgctctgg agatcttgtc
     4561 caaagcctac tgcatgtggg gctgtaaggc tgtaactaat agtttgaagg aggtgcagca
     4621 tttgcatcag gcagactctt ctgcttgggt gatactctgg tgtctggcca ctattgcatc
     4681 ccctcccgca ccagccccat ttgcaggcgt ttctgtcact ggagcaagca ggtctccatt
     4741 gtagcaaggc agattctctc actatttgtc tagttccttg tttggtttac actgtcattg
     4801 gagcaaattt gcatctgttt acaagaatta atcattgcag cccttaaagc tttggttaaa
     4861 ctgcaaagct ttgagcctgc tcatcagtcc catttcagga ctgctgtgtc ctttgccttg
     4921 catcgagtgt acacagtaac agccctttct ccacgggaga accctctggc tgcttccact
     4981 gaaacatagt acctctggag cagatgagct caacaggatt tcccctgctt ccctagaaac
     5041 aagctggggt gttaagacta cttgtcttca agcccctccc cttagctgaa tggtggaaaa
     5101 tggattttaa gcaaggaagt agaaatccta gctctttccc ttgtcatagc aataacatga
     5161 aaatttctgc aggagaaata aaagatactt ttcaaatgtg ttg
//
