LOCUS       NM_001106557             685 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus endothelial differentiation-related factor 1
            (Edf1), mRNA.
ACCESSION   NM_001106557 XM_001077770 XM_215993
VERSION     NM_001106557.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 685)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 685)
  AUTHORS   Busk,P.K., Wulf-Andersen,L., Strom,C.C., Enevoldsen,M.,
            Thirstrup,K., Haunso,S. and Sheikh,S.P.
  TITLE     Multiprotein bridging factor 1 cooperates with c-Jun and is
            necessary for cardiac hypertrophy in vitro
  JOURNAL   Exp Cell Res 286 (1), 102-114 (2003)
   PUBMED   12729799
  REMARK    GeneRIF: data suggest that multiprotein bridging factor 1 is a
            transcriptional coactivator of c-Jun regulating hypertrophic gene
            expression [MBF1]
REFERENCE   4  (bases 1 to 685)
  AUTHORS   Brendel,C., Gelman,L. and Auwerx,J.
  TITLE     Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear
            receptors that regulate lipid metabolism
  JOURNAL   Mol Endocrinol 16 (6), 1367-1377 (2002)
   PUBMED   12040021
REFERENCE   5  (bases 1 to 685)
  AUTHORS   Kabe,Y., Goto,M., Shima,D., Imai,T., Wada,T., Morohashi,Ki.,
            Shirakawa,M., Hirose,S. and Handa,H.
  TITLE     The role of human MBF1 as a transcriptional coactivator
  JOURNAL   J Biol Chem 274 (48), 34196-34202 (1999)
   PUBMED   10567391
REFERENCE   6  (bases 1 to 685)
  AUTHORS   Smith,M.L., Johanson,R.A., Rogers,K.E., Coleman,P.D. and
            Slemmon,J.R.
  TITLE     Identification of a neuronal calmodulin-binding peptide, CAP-19,
            containing an IQ motif
  JOURNAL   Brain Res Mol Brain Res 62 (1), 12-24 (1998)
   PUBMED   9795107
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001077770.1, XM_215993.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158849.1, CO400850.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..685
                     /gene="Edf1"
                     /gene_synonym="CAP-19"
                     /note="endothelial differentiation-related factor 1"
                     /db_xref="GeneID:296570"
                     /db_xref="RGD:1308073"
     exon            1..146
                     /gene="Edf1"
                     /gene_synonym="CAP-19"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..515
                     /gene="Edf1"
                     /gene_synonym="CAP-19"
                     /note="calmodulin-associated peptide-19; MBF1; EDF-1;
                     multiprotein-bridging factor 1; endothelial
                     differentiation-related factor 1 homolog"
                     /codon_start=1
                     /product="endothelial differentiation-related factor 1"
                     /protein_id="NP_001100027.1"
                     /db_xref="GeneID:296570"
                     /db_xref="RGD:1308073"
                     /translation="MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKW
                     AAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEK
                     PQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK"
     exon            147..198
                     /gene="Edf1"
                     /gene_synonym="CAP-19"
                     /inference="alignment:Splign:2.1.0"
     exon            199..359
                     /gene="Edf1"
                     /gene_synonym="CAP-19"
                     /inference="alignment:Splign:2.1.0"
     exon            360..453
                     /gene="Edf1"
                     /gene_synonym="CAP-19"
                     /inference="alignment:Splign:2.1.0"
     exon            454..685
                     /gene="Edf1"
                     /gene_synonym="CAP-19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgcgtcgcc gcgccgggtc tcgagcagct gccagagccg ccggacagac cgccgccccc
       61 gccgcgtcat ggccgagagt gactgggaca ccgtgacggt gctgcgcaag aagggcccca
      121 cggccgcaca ggccaagtct aagcaggcca tcttagcagc tcagcgacga ggagaagatg
      181 tggagacatc caaaaaatgg gctgctggcc agaacaagca gcattccatc actaaaaaca
      241 cagccaagct agaccgggag acagaggagc tgcaccacga cagggtgacc ctggaggtgg
      301 gcaaagtgat ccagcggggc cggcagagca aaggcctgac gcagaaggac ctggccacga
      361 aaatcaatga aaagccgcaa gtcatcgcag actatgaaag tggacgggcc attccgaata
      421 accaggtttt gggcaaaatt gagagagcca tcggcctcaa gctccggggg aaggacatcg
      481 ggaagcctat cgagaagggg ccgaaggcga aatgaacaca aagcctcgaa gccagtggtt
      541 ccggctgagc tcttctggct ggtcccccag gaccaccagc actgccgtgg gtctcctcac
      601 atggtcaaac ggaacatggg ggtcaggcct gtgtgccccc tcaacccata actgctgtca
      661 aacaaagcaa aaccttggaa agtga
//
