LOCUS       NM_001033068            4741 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus enhancer of mRNA decapping 4 (Edc4), mRNA.
ACCESSION   NM_001033068 XM_341679
VERSION     NM_001033068.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Jonas,S. and Izaurralde,E.
  TITLE     The role of disordered protein regions in the assembly of decapping
            complexes and RNP granules
  JOURNAL   Genes Dev 27 (24), 2628-2641 (2013)
   PUBMED   24352420
  REMARK    Review article
REFERENCE   2  (bases 1 to 4741)
  AUTHORS   Marnef,A., Maldonado,M., Bugaut,A., Balasubramanian,S., Kress,M.,
            Weil,D. and Standart,N.
  TITLE     Distinct functions of maternal and somatic Pat1 protein paralogs
  JOURNAL   RNA 16 (11), 2094-2107 (2010)
   PUBMED   20826699
REFERENCE   3  (bases 1 to 4741)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 4741)
  AUTHORS   Bloch,D.B., Rabkina,D., Quertermous,T. and Bloch,K.D.
  TITLE     The immunoreactive region in a novel autoantigen contains a nuclear
            localization sequence
  JOURNAL   Clin Immunol Immunopathol 72 (3), 380-389 (1994)
   PUBMED   7520377
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Sep 16, 2008 this sequence version replaced NM_001033068.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC103628.1, SRR26643296.38816.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-256               JAXUCZ010000019.1  50683924-50684179
            257-413             JAXUCZ010000019.1  50687469-50687625
            414-525             JAXUCZ010000019.1  50688006-50688117
            526-625             JAXUCZ010000019.1  50688391-50688490
            626-815             JAXUCZ010000019.1  50688692-50688881
            816-963             JAXUCZ010000019.1  50688989-50689136
            964-1068            JAXUCZ010000019.1  50689218-50689322
            1069-1178           JAXUCZ010000019.1  50689621-50689730
            1179-1262           JAXUCZ010000019.1  50689821-50689904
            1263-1358           JAXUCZ010000019.1  50689986-50690081
            1359-1461           JAXUCZ010000019.1  50690164-50690266
            1462-1642           JAXUCZ010000019.1  50690384-50690564
            1643-1715           JAXUCZ010000019.1  50690661-50690733
            1716-1807           JAXUCZ010000019.1  50690831-50690922
            1808-1995           JAXUCZ010000019.1  50690998-50691185
            1996-2129           JAXUCZ010000019.1  50691265-50691398
            2130-2286           JAXUCZ010000019.1  50691476-50691632
            2287-2723           JAXUCZ010000019.1  50691983-50692419
            2724-2828           JAXUCZ010000019.1  50692512-50692616
            2829-2981           JAXUCZ010000019.1  50692721-50692873
            2982-3018           JAXUCZ010000019.1  50692955-50692991
            3019-3196           JAXUCZ010000019.1  50693106-50693283
            3197-3352           JAXUCZ010000019.1  50693388-50693543
            3353-3468           JAXUCZ010000019.1  50693632-50693747
            3469-3634           JAXUCZ010000019.1  50693835-50694000
            3635-3821           JAXUCZ010000019.1  50694088-50694274
            3822-4041           JAXUCZ010000019.1  50694365-50694584
            4042-4205           JAXUCZ010000019.1  50694970-50695133
            4206-4741           JAXUCZ010000019.1  50695381-50695916
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..4741
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /note="enhancer of mRNA decapping 4"
                     /db_xref="GeneID:361399"
                     /db_xref="RGD:1562009"
     exon            1..256
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..4398
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /codon_start=1
                     /product="enhancer of mRNA-decapping protein 4"
                     /protein_id="NP_001028240.3"
                     /db_xref="GeneID:361399"
                     /db_xref="RGD:1562009"
                     /translation="MASCASIDIEDATQHLRDILKLDRPAGGSNVESQRPSSAYNGDL
                     NGLLVPDPLSSGDGNSTSKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVA
                     SSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVR
                     VISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGDLFVWRLALVKGKIQEEIL
                     VHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSH
                     STWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEP
                     RCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQ
                     TIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSI
                     SEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEESDSLGTESSHGAGTLESAAGVLIKL
                     FCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAPHGSQ
                     PDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPTASLQQISASPSSSSSSSSSSSS
                     SSSSSSSSSLTAVSAVSSSSAMDPSLPSRPPEELTLSPKLQLDGSLTISSSSSLQASP
                     RSLLPGLLPGPADKLIPKGPGQVSSGTSALSLDLQEVEPLGLPQASPSRTRSPDVISS
                     ASTALSQDIPEIASEALSRGFGSSVPEGLIEPDSMASAASALHLLSPRPRQGPELSSQ
                     LGLDGGPGDGDRHSTPSLLEAALTQEVATSDSQVWPTAPDITRETCSTLTESPRNGLQ
                     EKHKSLAFHRPPYHLLQQHDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPAKD
                     WKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVVEPPEDWPALIWQQQRELAELWH
                     NQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLT
                     QQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMK
                     ENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDS
                     FRLGTQEYLQQLDSHMKSRKAREQEAREPVLAQLRGLVSTLQNATEQMAATVSSSVRA
                     EVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPS
                     AHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLS
                     QPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQF
                     LQADPHNSLGKAARRLSLMLHGLVTPSLP"
     exon            257..413
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            414..525
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            526..625
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            626..815
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            816..963
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1068
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1178
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1262
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1358
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1461
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1642
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1715
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1807
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1995
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            1996..2129
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2286
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2723
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2828
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            2829..2981
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            2982..3018
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            3019..3196
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            3197..3352
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            3353..3468
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            3469..3634
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            3635..3821
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            3822..4041
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            4042..4205
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
     exon            4206..4741
                     /gene="Edc4"
                     /gene_synonym="LRRG00115; Nrn1l; RGD1309136"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttggcagg gctcacggac gcagtccggg cggcggtttg gggattgcgg gtaggttttg
       61 tgtagtgctc tgtcgtctcc tgctctctaa cggggtcgtg gctgggcgaa attggacact
      121 ttttggaggt agaggaacta acgtccggcg agcaggactc tcgtggctgg gcccatggcc
      181 tcctgcgcga gcatcgacat tgaggacgcc acgcagcatc tgcgggacat cctcaaactg
      241 gaccggcccg ccggaggctc caatgtcgaa agccaaaggc catccagtgc ctacaatgga
      301 gacctcaatg ggctcctggt cccagatccg ctcagttcag gagatggtaa ctcgacaagc
      361 aaacctggta tacggaccat gccacccatt aatctgcagg aaaagcaggt catttgcctc
      421 tctggagatg acagctccac gtgcattggg attttggcca aggaggtaga aattgtggcc
      481 agcagtgatt ctagcatttc cagcaaggcg cgagggagca acaaggtgaa aatccagcct
      541 gtagccaagt atgactggga gcagaaatac tactatggca acctgattgc agtgtctaac
      601 tccttcttgg catacgccat cagggctgcc aacaatggct cagccatggt ccgagtgatc
      661 agtgtgagca cttcggagcg gaccctgctc aagggcttca caggcagtgt ggctgacctt
      721 gcatttgcac acctcaactc tccacagctt gcctgcctgg acgaggccgg cgatctcttt
      781 gtgtggcgac tggctctggt taagggcaaa attcaagaag agatcttagt ccatatccgg
      841 caaccagagg gcacaccact gaaccacttc cgaaggatca tctggtgccc tttcatccct
      901 gaggaaagcg aggactgttg tgaggagagt agcccaacgg tggccctgct gcatgaagac
      961 cgggctgagg tgtgggactt ggatatgctt cgctccagcc acagcacatg gcctgtggat
     1021 gtcagccaaa tcaagcaggg ctttatcgtg gtaaaaggcc atagcacgtg cctaagtgaa
     1081 ggagcccttt cccctgatgg gactgtgctg gccaccgcaa gccatgatgg ctttgtcaag
     1141 ttctggcaga tctatattga aggtcaggat gagccaaggt gtctgcatga atggaaacct
     1201 catgatgggc ggcctctttc ttgcctcctg ttctgtgata accataagaa acaggatcct
     1261 gaggtcccat tctggaggtt cctcattact ggcgctgacc agaatcgaga gctgaagatg
     1321 tggtgcacag tgtcctggac ctgcctgcaa accattcgct tctccccaga tatcttcagt
     1381 tcagtgagtg tgcctcccag tctcaaagtt tgcttggacc tctcagcaga atatttgatt
     1441 cttagtgatg tgcaacgaaa ggtcctctat gtgatggagc tgctgcagaa ccaggacgag
     1501 ggccgtgctt gcttcagttc catctctgag ttcctgctca cccaccctgt gctgagcttt
     1561 ggcatccagg ttgtgagtcg ctgccggctg cggcacactg aggtgctgcc tgctgaggag
     1621 gagagtgaca gtctggggac tgagagttcc catggagctg gtaccttgga atctgcagct
     1681 ggtgtgctta tcaagctctt ttgtgtgcac actaaggcac tccaagatgt gcagatccgc
     1741 ttccagccac agctgaaccc tgatgtggtg gccccactct ctacccacac tgctcatgag
     1801 gacttcacat ttggagagtc tcgacctgaa ctaggctctg aggggctagc ttcagctcct
     1861 catggttccc agcctgacct ccgacgcatt gtggagctgc ctgcacctgc agacttcctc
     1921 agtctgagca gtgagaccaa gcctaagttg atgacacctg atgctttcat gacacctacc
     1981 gcctccctgc agcagatctc tgcatcccct agtagtagca gcagcagtag cagcagcagc
     2041 agtagcagca gcagcagtag cagcagcagc tctctaacag ctgtgtctgc tgtgagcagc
     2101 tcctcagcca tggacccctc cttgcccagt aggccacccg aggaactgac cttgagcccc
     2161 aaactgcagc tagatggcag cctgactata agcagcagca gcagcctgca ggcaagccct
     2221 cggagccttc ttccgggcct gctcccaggc ccagctgaca aactaattcc caagggacct
     2281 ggtcaggtat cttctggtac ttctgcacta tccttggatt tgcaggaagt ggaaccatta
     2341 gggctacccc aggcctcccc aagtcgcaca cgttctcctg atgtgatctc ctcagcatcc
     2401 actgccctgt cccaggacat ccctgaaatt gcatctgagg ccctgtcccg tggctttggc
     2461 tcctctgtac ctgagggcct cattgagcca gacagcatgg cctcagctgc ctcagcacta
     2521 cacctactgt ctcctcggcc caggcaaggc cctgagctta gttctcagct tggtctagat
     2581 ggaggccctg gggatgggga taggcatagt accccttccc tactggaagc agccttgacc
     2641 caggaagttg caacctctga cagtcaagtc tggcctacag cacctgacat tactcgtgag
     2701 acctgtagca cactaacaga aagccccagg aatggcctcc aggaaaagca caaaagcctg
     2761 gccttccaca ggccacctta tcacctgctg cagcaacatg acagtcagga cacaagtgct
     2821 gagcaaagtg accatgacga tgaggttgcc agccttgcct ctgcttcagg aggttttggc
     2881 agcaaaattc ctactccacg gctgcctgcc aaggattgga aaaccaaggg atcccctagg
     2941 acttcaccta agctcaagag gaaaagcaag aaggatgatg gggattcagc tgtgggatct
     3001 cggctcaccg agcaccaggt ggtagagccc cctgaagact ggccagcact aatttggcag
     3061 cagcaaagag agctggcaga actatggcac aaccaagaag agctgctaca gcgtctttgt
     3121 gcccaacttg aaggtcttca gagcactgtc acagaccatg tagaacgtgc cctggagaca
     3181 cggcatgagc aagagcaacg gcgactggag cgggcactgg ctgaggggca gcaacggggt
     3241 gggcagctac aggagcagct gacacagcag ctatcccagg ctttgtcttc agctgtggct
     3301 gggcggctag agcgcagcat aagggatgaa atcaagaaaa cagttcctcc atgtgtctcc
     3361 agaagtctgg agcctgtggc aggccaacta agcaactcag tggctaccaa gcttacagct
     3421 gtggaaggca gcatgaaaga gaatatctct aagctactca agtccaagaa cttaacagat
     3481 gccattgccc gcgcagctgc agatacgcta cagggaccaa tgcaggctgc ctaccgagaa
     3541 gccttccaga gtgtggtgct gccggctttt gagaagagtt gtcaggctat gttccagcaa
     3601 atcaatgaca gcttcaggct gggcactcag gaatatttgc agcagctgga cagtcacatg
     3661 aagagccgaa aggcacgtga acaagaagct agggagcctg tgttggccca gcttcggggc
     3721 ctggtcagca cactgcagaa tgccactgag cagatggcag ccactgtgtc tagcagtgtt
     3781 cgggccgagg tgcaacacca gctgcatgtg gctgtgggca gcttgcagga atcaatctta
     3841 gcacaagtac aacgcattgt caagggtgaa gtgagtgtgg cactgaagga gcagcaggcc
     3901 actgtcactt ccagcatcat gcaggctatg cgctcagctg ctggcacacc tgtcccctct
     3961 gcccaccttg actgccaggc ccaacaagcc catatcttgc agttactgca gcagggccac
     4021 ctcaatcagg ccttccagca ggctctgact gctgctgatc tcaacctggt gctgtatgtg
     4081 tgtgaaactg tggacccagc ccaggttttt gggcagccgc cctgtccact gtcccagccc
     4141 gttctccttt ccctaatcca gcagctagca tctgaccttg gaactagaag tgacctcaag
     4201 ctcagctact tggaagaggc tgtgatgcac ctggaccaca gcgatcccat cactcgagac
     4261 cacatgggct ctgtcatggc tcaggtgcgc cagaagctct tccagttcct gcaggctgat
     4321 ccacacaact cacttggcaa agctgcccgc cgcctcagcc taatgttaca cggccttgtg
     4381 acccctagcc tcccttagcc atttaaacag ggatggggtg acactgaagg ccagttggca
     4441 ggtttaggtc aaggcagggc cgtgtctgct gttttcctgc tcaggccttc atctctggtg
     4501 tttggaggga ggtaagcagc cgggcacact ggcagtggtc tactgattgt ggtaaccagc
     4561 agggttaggc tgggcccagg gcaggtattg tgccttcttg ggtcctgcca tgcctgaagc
     4621 atgaccccaa gatcgtgaca ccacttgagt tgaattttcc atgttccttt ttacctctaa
     4681 tttggatctt tttgtttttg aaaaacattg agaaattcaa ttaaaggctt ttggaataaa
     4741 a
//
