LOCUS       NM_001007734            1888 bp    mRNA    linear   ROD 10-APR-2024
DEFINITION  Rattus norvegicus ethylmalonyl-CoA decarboxylase 1 (Echdc1),
            transcript variant 1, mRNA.
ACCESSION   NM_001007734 XM_341744
VERSION     NM_001007734.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Linster,C.L., Noel,G., Stroobant,V., Vertommen,D., Vincent,M.F.,
            Bommer,G.T., Veiga-da-Cunha,M. and Van Schaftingen,E.
  TITLE     Ethylmalonyl-CoA decarboxylase, a new enzyme involved in metabolite
            proofreading
  JOURNAL   J Biol Chem 286 (50), 42992-43003 (2011)
   PUBMED   22016388
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079052.1.
            
            On Nov 29, 2004 this sequence version replaced XM_341744.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079052.1, CK470945.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..1888
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /note="ethylmalonyl-CoA decarboxylase 1"
                     /db_xref="GeneID:361465"
                     /db_xref="RGD:1359654"
     exon            1..138
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /inference="alignment:Splign:2.1.0"
     exon            139..354
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..1040
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /EC_number="4.1.1.94"
                     /note="isoform 1 is encoded by transcript variant 1;
                     enoyl-CoA hydratase domain-containing protein 1; enoyl
                     Coenzyme A hydratase domain containing 1;
                     methylmalonyl-CoA decarboxylase; enoyl CoA hydratase
                     domain containing 1"
                     /codon_start=1
                     /product="ethylmalonyl-CoA decarboxylase isoform 1"
                     /protein_id="NP_001007735.1"
                     /db_xref="GeneID:361465"
                     /db_xref="RGD:1359654"
                     /translation="MAKSLLASSLSVRTKILQTGVSLYNTTHGFHEEEVKKILEQFPG
                     GSIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNT
                     FCSGSDLNAVKALSTPENGVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTA
                     CDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKLDSKEALRI
                     GLADEVLQPSDEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERD
                     VLETLWGGPANLEAIAKKGKHTK"
     exon            355..497
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /inference="alignment:Splign:2.1.0"
     exon            498..550
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /inference="alignment:Splign:2.1.0"
     exon            551..631
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /inference="alignment:Splign:2.1.0"
     exon            632..1866
                     /gene="Echdc1"
                     /gene_synonym="MMCD"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggtctct ggaggagctc tgaggcgtta cagagaaggt gggaaaatag ctgcgttggc
       61 gatttcaaag gatgaggagg tttggggtca actctaagct gatttctaaa tactttggag
      121 tctgttgtga gaattgagaa atggcaaaaa gtctcttggc ttcatctctg tctgtaagaa
      181 caaaaatctt acaaacagga gtgtcacttt ataatacgac tcatggcttc catgaggaag
      241 aagtgaagaa gatactggag cagtttcctg gtggatccat tgacctacag aagaagcaga
      301 atggtattgg cattctgacg cttaacaact caaataaaat gaatgctttc tcaggtgcca
      361 tgatgctaca acttttggaa agggtaattg aattagaaaa ttggacagaa gggaaaggcc
      421 tcattgttca tggagcgaaa aatacttttt gctcaggatc tgatctgaat gctgtgaagg
      481 cactctccac tccagagaat ggagtggccc tgtctatgtt catgcaaaac accttaacaa
      541 gatttatgag actaccatta ataagcgttg ctctggttca aggctgggca atgggtggag
      601 gagcagaact tactacagca tgtgatttca ggttgatgac tgaggaaagt gtgatcagat
      661 ttgtccacaa ggagatgggt atagttccaa gctggggtgg tgccagccgg ctggttgaaa
      721 tcattggcag cagacaagct ctcaaagtgt taagtgggac attcaaactg gattccaagg
      781 aagctttaag aataggtttg gctgatgagg tcttgcagcc ctcagacgaa gctacggctc
      841 tggaacaggc acaagagtgg ctggagcagt ttgtcagtgg acctgcacaa gtcataaggg
      901 gtttgaaaaa atctgtctgc tctggccggg aactgtatct agaggaggcg ttacagaacg
      961 aaagagatgt tttagaaaca ctgtggggtg gacctgcaaa tttagaggct attgctaaga
     1021 aaggaaaaca cactaaatag tgtttaaaat gtgagtgtac tccaagtgaa gctgcaggga
     1081 gagcgtgcgt ggaggtgaga tggtattaga aaggagcagc ggaagtcatt cgaaggggac
     1141 tgctaatctg cttacttggt ttgggtggca ttctctgtat ttcaattcag tgctcttttc
     1201 tgtcttgttt aacatttaac acttctgcca acttctacat tcctgtagta attcttatcc
     1261 tgagcttatg ttttataaca tacttattaa acttaaactt gctgttgtgc caagggtagt
     1321 catgactctc ctgccaccac ctcccaaacg ctcattaata ctgctgtttg tggctctttt
     1381 gttctttctt aagttgaagt aatttacaaa agcaaagtca agaacaaatt taaaagacct
     1441 tagcaaatct ttcatatgaa gttaaaagga gggagattag agaggcatat aagaaatatt
     1501 agggtttttt gtctgctcta gatattgagg ggaaatggtt cttcatttaa agaaaaataa
     1561 ggtgcatctt tgcctctgtt tttggagctt tttttggtct tttcaaccat ctgacttcta
     1621 atttaaaaga cctaaagagt gaaagccgtt ctactgagca ccaactggct atacaaagta
     1681 gcattgcgtt ggaattttca aggtaacagt aaaacagtag tagtgttgat agggttttta
     1741 aatctaaact attaaagatt catgaagtat ccttttcatt gttaccatat ttagttttga
     1801 ggaatgtcta actttttgtg tgactatgtt ttaataacta aattcaataa aaacacataa
     1861 cccaaaaaaa aaaaaaaaaa aaaaaaaa
//
