LOCUS       XM_039088566            1999 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus endothelin-converting enzyme 2 (Ece2),
            transcript variant X4, mRNA.
ACCESSION   XM_039088566
VERSION     XM_039088566.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051346.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039088566.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1999
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1999
                     /gene="Ece2"
                     /note="endothelin-converting enzyme 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 ESTs, 2 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     63 samples with support for all annotated introns"
                     /db_xref="GeneID:408243"
                     /db_xref="RGD:1303039"
     CDS             202..1860
                     /gene="Ece2"
                     /codon_start=1
                     /product="endothelin-converting enzyme 2 isoform X4"
                     /protein_id="XP_038944494.1"
                     /db_xref="GeneID:408243"
                     /db_xref="RGD:1303039"
                     /translation="MNVALQELGSGGSMVEYKRAKLQDEELPEVTVEGRAIQDSLEVG
                     SQKRTRQLFGSHTQLELVLAGLILVLAALLLGCLVALWVQYHRDPVHSTCITEACIRV
                     AGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPSGRSRWNTFNSLWDQNQAILKHLLE
                     NSTFNSSSEAERKTRSFYLSCLHLERIEKLGAKPLQDLIDKIGGWNITGPWDEDNFME
                     VLKAVAGTYRAAPFFTVYVGADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLAA
                     YLDYMVELGMLLGGQPTSTRAQMQQVLELEIQLATITVPQDQRRDEEKIYHKMSISEL
                     QTLAPSMDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWN
                     LVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKAT
                     FDRQSKEIAEGMISEIRAAFEETLENLVWMDEKTRLAAKEKADAIYDMIGFPDFILEP
                     RELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQ"
ORIGIN      
        1 ccccctcgct cccacccccg ggcgcgccgc tgggtggggg agacccgaga aagcgggggc
       61 cgcggctgcc aagccagggg ctgcagccgt ggctgtgatg gagggccgcg gcggggttca
      121 gcagttggcc tgggccgtag ttcctgggcg ggtcaacctc gcccagccct aaggcgcggc
      181 ccagccctgc tccactccac catgaacgtc gcgctgcagg agctgggtag cggaggcagt
      241 atggtggagt acaaacgagc taagcttcag gatgaagaat taccagaggt gacagtagaa
      301 ggcagggcca tccaggactc actggaggtg ggatcccaga agaggacaag acaactcttt
      361 ggctcacaca cacagttgga gctggtcttg gcaggcctca ttctagtgtt ggctgccctt
      421 cttttgggct gcctcgtggc tctgtgggtc cagtaccaca gagacccagt ccacagcacc
      481 tgcatcacag aagcctgcat tcgagtggct ggaaaaatcc tggagtcttt agaccgtggg
      541 gtgagcccct gtcaggactt ttaccagttc tcctgtggag gctggattcg aagaaaccct
      601 ctacccagtg gacgttctcg ctggaacacc ttcaacagcc tttgggacca gaatcaggcc
      661 atactgaagc acctacttga gaatagcact ttcaattcca gcagtgaagc cgagcggaag
      721 actcggagtt tctacctgtc ctgcctgcac ctggagcgca tcgagaagct aggagccaag
      781 ccacttcaag acctcattga caagatcggt ggttggaaca tcacggggcc ctgggatgag
      841 gacaacttca tggaagtgct aaaggcagta gcagggacct atagagccgc cccattcttc
      901 actgtctatg tcggtgctga ttcgaagagt tctaacagca acatcatcca ggtggaccag
      961 tctgggcttt ttctaccctc tcgtgattac tacctaaata gaactgccaa tgagaaagtt
     1021 ctcgctgcct acctggacta catggtggag ctgggaatgc tgctgggtgg acagccgacc
     1081 tccacccggg cgcagatgca gcaggtgctg gaactggaga tacaactggc taccatcact
     1141 gtgccccagg accagcggcg tgatgaggag aagatctatc acaagatgag catctcagag
     1201 ctgcagactc tagcaccctc catggactgg ctggagttcc tttctttctt gttgtcgcca
     1261 cttgagttgg gcgattctga gcctgtggtg gtgtatggga ctgagtattt acagcaggtg
     1321 tcggagctca ttaaccgtac ggaaccaagc atcctgaaca attacctaat ttggaacctg
     1381 gtgcagaaga caacctcgag cctcgaccag cgctttgaga ctgcacagga gaagctactg
     1441 gagaccctct acggtaccaa gaagtcctgc accccgaggt ggcagacctg catctccaat
     1501 acagatgatg cccttggctt cgctctgggc tcgctctttg tgaaggccac atttgaccga
     1561 caaagcaagg aaattgccga ggggatgatc agtgaaatcc gtgctgcttt tgaggagact
     1621 ctggaaaact tggtttggat ggacgagaag acccggctgg cagccaagga gaaagcagat
     1681 gccatctatg atatgattgg tttccctgat ttcatcttgg agcccagaga actggatgat
     1741 gtttatgatg ggtatgaagt ctctgaagat tcttttttcc aaaacatgct gaacctatac
     1801 aacttctcag ctaaggtgat ggctgaccag ctccgcaaac ctcccagccg agaccagtga
     1861 gaatgagcgg gcagacatag ggcagccaga gaggtggagc atgacgcctc agactgtgaa
     1921 cgcttactac cttccaacca agaatgaaat cgtcttccct gctggcatct tgcaggcccc
     1981 cttctatgct cacaaccac
//
