LOCUS       NM_001159493            1961 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus glutamyl-tRNA synthetase 2, mitochondrial
            (Ears2), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001159493 XM_001079468 XM_341920
VERSION     NM_001159493.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1961)
  AUTHORS   Nagao,A., Suzuki,T., Katoh,T., Sakaguchi,Y. and Suzuki,T.
  TITLE     Biogenesis of glutaminyl-mt tRNAGln in human mitochondria
  JOURNAL   Proc Natl Acad Sci U S A 106 (38), 16209-16214 (2009)
   PUBMED   19805282
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Apr 19, 2009 this sequence version replaced
            XM_001079468.1, XM_341920.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.2178.1,
                                           SRR26643286.2847.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-182               JAXUCZ010000001.1  186056893-186057074 c
            183-338             JAXUCZ010000001.1  186052815-186052970 c
            339-528             JAXUCZ010000001.1  186046181-186046370 c
            529-1001            JAXUCZ010000001.1  186039721-186040193 c
            1002-1110           JAXUCZ010000001.1  186038124-186038232 c
            1111-1264           JAXUCZ010000001.1  186035615-186035768 c
            1265-1395           JAXUCZ010000001.1  186035403-186035533 c
            1396-1531           JAXUCZ010000001.1  186030215-186030350 c
            1532-1961           JAXUCZ010000001.1  186029236-186029665 c
FEATURES             Location/Qualifiers
     source          1..1961
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..1961
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /note="glutamyl-tRNA synthetase 2, mitochondrial"
                     /db_xref="GeneID:361641"
                     /db_xref="RGD:1307904"
     exon            1..182
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..1615
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /EC_number="6.1.1.17"
                     /note="probable glutamyl-tRNA synthetase, mitochondrial;
                     probable glutamate--tRNA ligase, mitochondrial;
                     glutamyl-tRNA synthetase 2 mitochondrial (putative)"
                     /codon_start=1
                     /product="nondiscriminating glutamyl-tRNA synthetase
                     EARS2, mitochondrial"
                     /protein_id="NP_001152965.1"
                     /db_xref="GeneID:361641"
                     /db_xref="RGD:1307904"
                     /translation="MAALRKSLLLAGPHVGALGHRVGRREASLGPDPGVTVRVRFAPS
                     PTGFLHLGGLRTALYNYIFAKKHQGSFILRLEDTDQSRLVPGAAENIEDMLEWAGIPP
                     DESPRQGGPAGPYYQSQRLALYAQATEALLKSGAAYPCFCSPQRLELLKKEALRSRQT
                     PRYDNRCRNLSQAQVAQKLATDPKPAIRFRLEEAVPAFQDLVYGWTQHEVASVEGDPV
                     ILKSDGFPTYHLACVVDDHHMSISHVLRGSEWLVSTSKHLLLYQALGWQPPQFAHLPL
                     LLNRDGSKLSKRQGDIFLEHFAATGFLPEALLDIITNCGSGFAENQMGRTLPELITQF
                     DLTRITCHSALLDLEKLPEFNRLHLRRLVSSETQRPHLVEKLQGLVKEAFGSELQDRD
                     VLDPAYMERILLLRQGHISRLQDLVSPVYSYLWTRPAVHRAELGASSEKLDVIAKHLL
                     GLLERPGLSLTQDVVNRELKKLSEGLEGTKHSSVMKLLRMALSGQLQGPPVAEMMVSL
                     GPEEVRERIQKVLSS"
     exon            183..338
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     exon            339..528
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     exon            529..1001
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1110
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1264
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1395
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1531
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
     exon            1532..1961
                     /gene="Ears2"
                     /gene_synonym="RGD1307904"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagtgacgt gcgaagaagc ccacgtgtgt gtttctattc cacatggcgg cgctccgcaa
       61 gagccttctg ctggccgggc ctcacgtggg ggccctcggg caccgcgtgg gtcggcgcga
      121 ggccagtctg ggcccagatc ccggggtcac ggtgcgagtg cgcttcgctc ccagccccac
      181 aggcttctta cacctgggtg gcctccgtac tgccctctac aactacatct ttgccaagaa
      241 gcaccaaggg agcttcattc tgaggctgga ggacactgat cagagccgcc tggtaccggg
      301 ggcagcagaa aacattgagg acatgctgga gtgggcaggc atcccacctg atgaaagtcc
      361 ccgccagggt ggtcctgcag ggccctacta tcagtcacag cggctagctc tgtatgccca
      421 ggccacagaa gcattgctga aatctggagc tgcctatccc tgtttctgtt caccacagcg
      481 gctggagctc ctgaagaagg aagcactgag gagccgtcag acacctcggt atgacaatcg
      541 atgccggaac ctgagccagg cacaggtggc ccagaagctg gccacagacc ccaagcctgc
      601 tatccgcttt cgcctagagg aagcagtacc agccttccaa gacctggtat atggctggac
      661 tcagcatgaa gtggccagtg tggaggggga cccagttatc ctgaaaagtg atggctttcc
      721 tacctaccac ctagcctgtg tggtagatga ccaccacatg agcatcagcc atgtacttcg
      781 gggctctgag tggctggtct ctacatccaa gcacttgctc ctctaccagg ccctgggttg
      841 gcagccacct caatttgctc atctgcccct gctcctcaac agggatggta gcaagctgtc
      901 taagaggcaa ggggacattt tcctggaaca tttcgctgcc accggttttc ttccagaagc
      961 cttgcttgac atcatcacca actgtggctc ggggtttgca gagaaccaaa tgggcaggac
     1021 cctgccggag ctgattacac agtttgacct gactcggatc acctgccact cagccctgct
     1081 ggacctagag aagctcccag aattcaacag gctgcacctc cgccggctgg tgagcagtga
     1141 gacccagagg ccccatttgg tggagaagtt gcagggcctg gtgaaggagg catttgggag
     1201 cgaactgcaa gacagggatg ttctggaccc agcatatatg gagaggatcc tcctgctgcg
     1261 acagggtcac atcagccgtc tgcaggatct ggtctcccca gtgtactcct acttatggac
     1321 ccgccctgct gtccatcgag cagagctggg cgccagctcg gaaaagttgg atgtgattgc
     1381 caaacacttg ctggggcttt tagaaagacc tggtttaagc ctaactcagg atgtggtgaa
     1441 cagagaactg aagaagttgt cagaaggcct ggaaggcacc aagcatagca gcgtgatgaa
     1501 gctcctccgg atggccctca gtggacagct gcaaggaccc cctgtggctg agatgatggt
     1561 gtccttgggc ccagaggaag tacgggaacg aatccagaag gtgctttcta gctagggaaa
     1621 ggatgcatag gacgatggag gtgaccctga gagcctctac acatggaaac tgaattctaa
     1681 ggagagcagg gcctggggcc tactaggacc ctttcagaat gaacagcagt agaaacaggc
     1741 tctctgacta ctctcagctg gcctctgggg agcctggctt gtttcacctt gttaactctg
     1801 ggaaggatga acttgaaccc ctgttgtgat tcttttctat ttttttttta aagattttat
     1861 ttttaaatgt atatgggtgt tttgcctcca tgtatgcctg tgtaacacat acatgcatat
     1921 atgcagaacc tgcaaaggcc aaaggggagc attggatcac c
//
