LOCUS       NM_001014095            3608 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DAZ interacting zinc finger protein 1-like
            (Dzip1l), mRNA.
ACCESSION   NM_001014095 XM_236602
VERSION     NM_001014095.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3608)
  AUTHORS   Wang,C., Li,J., Takemaru,K.I., Jiang,X., Xu,G. and Wang,B.
  TITLE     Centrosomal protein Dzip1l binds Cby, promotes ciliary bud
            formation, and acts redundantly with Bromi to regulate ciliogenesis
            in the mouse
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29487109
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3608)
  AUTHORS   Lu,H., Galeano,M.C.R., Ott,E., Kaeslin,G., Kausalya,P.J.,
            Kramer,C., Ortiz-Bruchle,N., Hilger,N., Metzis,V., Hiersche,M.,
            Tay,S.Y., Tunningley,R., Vij,S., Courtney,A.D., Whittle,B.,
            Wuhl,E., Vester,U., Hartleben,B., Neuber,S., Frank,V., Little,M.H.,
            Epting,D., Papathanasiou,P., Perkins,A.C., Wright,G.D.,
            Hunziker,W., Gee,H.Y., Otto,E.A., Zerres,K., Hildebrandt,F.,
            Roy,S., Wicking,C. and Bergmann,C.
  TITLE     Mutations in DZIP1L, which encodes a ciliary-transition-zone
            protein, cause autosomal recessive polycystic kidney disease
  JOURNAL   Nat Genet 49 (7), 1025-1034 (2017)
   PUBMED   28530676
REFERENCE   3  (bases 1 to 3608)
  AUTHORS   Glazer,A.M., Wilkinson,A.W., Backer,C.B., Lapan,S.W., Gutzman,J.H.,
            Cheeseman,I.M. and Reddien,P.W.
  TITLE     The Zn finger protein Iguana impacts Hedgehog signaling by
            promoting ciliogenesis
  JOURNAL   Dev Biol 337 (1), 148-156 (2010)
   PUBMED   19852954
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC083786.1.
            
            On Apr 20, 2005 this sequence version replaced XM_236602.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083786.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3608
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..3608
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /note="DAZ interacting zinc finger protein 1-like"
                     /db_xref="GeneID:315952"
                     /db_xref="RGD:1311430"
     exon            1..34
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            35..610
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..2440
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /note="zinc finger protein DZIP1L; DAZ-interacting protein
                     1-like protein; DAZ interacting protein 1-like"
                     /codon_start=1
                     /product="cilium assembly protein DZIP1L"
                     /protein_id="NP_001014117.1"
                     /db_xref="GeneID:315952"
                     /db_xref="RGD:1311430"
                     /translation="MQYSVATADGLSGPPSGAYTLPTFKFQPRRESIDWRRISAVDVD
                     RVARELDVATLQENIAGVTFCNLDREVCNHCRQPVDPVLLKVLRLAQLIIEYLLHCQD
                     CLSASVAQLEARLQASLGQQQRGQQELGRQADELKGVREESRRRRKMISTLQQLLLQT
                     GAHSYHTCHLCDKTFMNATFLRGHIQRRHAGMAEVGKQKQEQQLGEVLEELRAKLKWT
                     QGELEAQREAERQRQAQELEMIRQREIEAKKKFDEWKEKERSKLYGEIDKLKQLFWDE
                     FKTVANQNSTLEEKLKVLQSYSMTESHLGSLRDEESEERLKHAQELQALREKMDIQKT
                     EWKRKMKALHEERAAERRQLQEENERLHVTLSQDQKKAAAQSQRHINALRAQLQEQAR
                     LIESQEETIQTLSFRRMEEVQEVPKAVVTEEDSSEEELEASLEEQQEQRKVLAALRNN
                     PAWLKQFRPILEDTLEEKLEGMGIKRGTKGISAQTVRRLEPLLRTQREQTARSFREFL
                     SLREKLNQEVSSRAKKRWEGTAVVPQPDGQPPVKSQRTTLATREVRPKTRTLTVALPS
                     KPAEPSTSTPRGHSSHGPGLTQVSTPIPRPRVHGPSSTPVSPGPGLSTPPFSSEEEPE
                     GDVVQRVSLQPPKVLPRSAPQPEDNWGWSDSETSEESAQSPGKGSDGLASSATLVQSM
                     VKNLEKQLETPAKKPSGGVNMFLRPNTALQRSSTPARKTQLSEDESDLEISSLEDLSH
                     DLGPKGKPTPLSHSKLPEKFDASPWSSGSRPRIPGW"
     exon            611..695
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            696..814
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            815..976
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1105
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1168
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1309
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1340
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1394
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1395..1537
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1730
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1731..1947
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2135
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            2136..2275
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
     exon            2276..3580
                     /gene="Dzip1l"
                     /gene_synonym="RGD1311430"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctggcggtga ggctgcagcc tggagctaag catggtcctc tttcagctcc ttggccagtg
       61 gccttggtgg cattctactc ccgtggtcag cccagagcct ctcctgccca tgcagtactc
      121 agtagccact gctgacggcc ttagcggccc gccgtccggg gcctacacac ttcccacctt
      181 caagttccag cctcgccgtg agagcataga ctggaggcgc atcagtgctg tggacgtgga
      241 ccgtgtggcc cgggagctgg acgtggccac tctgcaggag aacattgctg gcgtcacctt
      301 ctgtaacttg gaccgagagg tgtgcaacca ctgtaggcag cctgtggacc cagttctgct
      361 caaggtgctg cgcttggcgc agctcatcat cgagtacctg ctgcactgcc aggactgcct
      421 gagtgccagt gtggcccagc tggaagcacg gctgcaggcc agcctgggcc agcagcagcg
      481 tggccagcag gagctgggtc gccaggctga tgagctcaag ggtgttcggg aggagagccg
      541 gcgcaggcga aagatgatca gtaccctgca gcagctgctt ctgcagacag gcgcccacag
      601 ctaccacacg tgccatttgt gtgacaagac gttcatgaat gccacctttc tccggggcca
      661 catccagcgc aggcatgcag gcatggcgga agtcgggaag cagaagcagg aacagcagct
      721 gggggaggtg ctggaggagc ttcgggccaa gctcaagtgg acccaagggg agctggaagc
      781 ccagagggag gctgagcggc agcggcaggc ccaggaatta gagatgattc gtcagaggga
      841 aatagaagct aaaaagaagt tcgatgaatg gaaagaaaaa gaacggagca agctttatgg
      901 ggaaatagac aagctgaaac agctcttttg ggatgaattt aaaactgttg ccaaccagaa
      961 ctctacatta gaagagaagc tgaaggtgct gcagtcctac agtatgactg agtctcacct
     1021 cgggtctctg cgggatgaag agtcagagga gagactcaag catgcccagg agctccaggc
     1081 ccttcgagaa aagatggaca ttcagaaaac tgagtggaag agaaaaatga aggccctgca
     1141 tgaagagcgg gcagctgaga ggagacagct gcaggaggag aacgagaggc ttcatgtcac
     1201 gctgtctcag gatcagaaga aagcggcagc ccagtcccag cgccacatca atgcccttcg
     1261 tgcccagctg caggaacaag ccaggcttat tgagtcacag gaggagacga tccagacttt
     1321 gtccttcagg aggatggagg aagtccaaga ggtgccaaag gctgtggtca cagaggagga
     1381 ctcttctgag gaagagctgg aggcctccct cgaggagcag caggagcaaa ggaaggtgtt
     1441 agcagctctc aggaacaacc ctgcttggct gaagcagttc cggcccatcc tggaggacac
     1501 cctggaagag aagctggagg gcatggggat aaagaggggc acaaagggaa tttcagccca
     1561 gactgtccga cgcctggagc ccctgctgag aacacaaagg gagcagacag cccgaagctt
     1621 ccgagaattt ctcagtctga gggaaaaact caaccaggaa gtgagcagca gggcgaagaa
     1681 gagatgggag ggtacggctg tggtgcccca gccagatggc cagcctccag tcaaaagcca
     1741 gcggaccaca ctggccacaa gggaggtccg gccaaagacc aggaccctga ctgtggcact
     1801 gccatccaag ccggcagagc cttctacatc aacccctcga ggccacagca gccatggccc
     1861 cggcctcacc caggtgtcca cccccattcc acgccccaga gtgcatggac cctccagtac
     1921 ccccgtttcc cctgggcccg ggctgagcac cccacctttc agttctgaag aagagccaga
     1981 gggagacgtc gtacaacgtg tgtctcttca gcctcctaaa gttctcccta ggtcagcacc
     2041 ccagcctgag gacaactggg gctggtctga ttctgagacc tcagaggaga gtgcccaatc
     2101 ccctgggaag ggctcagatg ggctggcttc ctcagcaaca ctggtacagt cgatggtcaa
     2161 aaacctggag aaacagcttg aaaccccagc aaagaagcct tctggagggg tcaatatgtt
     2221 cttaagaccc aacactgccc ttcagaggtc ttctacacca gcaaggaaga ctcagctttc
     2281 agaagatgaa agtgacttgg agatctcgtc tttggaagat ctctcccatg acctgggccc
     2341 aaaaggaaag ccaacacctt tgtcccactc gaagctccca gaaaagtttg atgccagccc
     2401 ttggagctct gggtcacgac ccaggattcc tggctggtga ttctgccaga gggcttagcc
     2461 ttgtttcttg gctggtcttc cccaaatgga agaaactgtc aggcctccca ctctcactag
     2521 cagccaagaa gtctttccct tgaagacaaa cagagcagga gacagatggg acctctatcc
     2581 attccctgac ggtcacccca aaaggctgcg tcctgatgct gtgtcttgtt taaacgtgag
     2641 gattataaca ggacttccaa gtgtttcttc catgatccca gcccagactg aaagtagtta
     2701 ttgtttctaa gtttttgtca tctgcaggtc actgtggcgt tgggtcctga gttaggtagt
     2761 ctatggtgga ctctctagct tttcactaca gagttggggt gcagacagag gtaggaggtg
     2821 caaagtgcct gctgccaggg ctaggcatag taatcaaatg ctaggcatca gagtgttatg
     2881 ggctgccagg gccaggcata gtaatcgagt gctatgcatc agagtgttat acgggcatgg
     2941 gagaggctgg ctgccctact ttcgtttctg ttgctgtgat aaacactcta accaaaagca
     3001 ccttagagac tttgttgatc tatgactgtg agaggtgaag gctggaatgt taaggtaggt
     3061 ttgcacacag cactacctct gaccaaggaa ttcactctat agccaaagaa acactaggaa
     3121 ccatagagga tactgcttgc tggctgcagc tgtacgtact cagctagctt ttttatacag
     3181 ctcagcaccg cctgcctagg gatggtactg cccacagtag gctgggttct tctgtgtgtg
     3241 tgaacaatct agacaatccc tcacagacat tgccctcaaa gcacttcctc tatggaggct
     3301 ctcagctgtg gtgaagggat atgcaaaact aaccaggaca ccattccacc ctgccccgga
     3361 tgacccatag aaccacaaat ttaatttttg agatcatttc tgactgagtt ttttatatat
     3421 tgactgtatt tttggttgga gagggtttgg gttttgagac agggtttctc tgtgtagccc
     3481 tggctgtcct ggaactcttt ctacagacca ggccgccctt gaactcagag atctgcctgc
     3541 ttctgcctcc tgagcgctga gattaaaggt gtgcatggtg aaaaaaaaaa aaaaaaaaaa
     3601 aaaaaaaa
//
