LOCUS       XM_017592630            6716 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dysferlin (Dysf), transcript variant
            X2, mRNA.
ACCESSION   XM_017592630
VERSION     XM_017592630.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017592630.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017592630.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6716
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6716
                     /gene="Dysf"
                     /note="dysferlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 23 ESTs, 1 long SRA read,
                     1 Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 6 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
     CDS             48..6491
                     /gene="Dysf"
                     /codon_start=1
                     /product="dysferlin isoform X2"
                     /protein_id="XP_017448119.1"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
                     /translation="MLRVFILFAENVHTPDSDISDAYCSAVFAGVKKRTKVIKNSVNP
                     VWNEGFEWDLKGIPLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSLSASFN
                     APLLDSKQQPTGASLVLQVSYTPPPGAAPLFPPPASLAPSPTLPDMDLVAGGGQSRAE
                     TWSLLSDSTMDTRYSGKKWPVPTDTGGEEDTEDQGLTGDEAELFPDPSVAVGPGGPTT
                     PKKPPSHPPPHYPGGKRKRSSAPPRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKV
                     TAAGQTKRTRIQKGNSPLFNETLFFNVFDSPLELFDEPIFITVVDSRSLRTDALLGEF
                     RMDVGTVYREPRHAYLRKWLLLSDPDDFSAGARGYLKASLCVLGPGDEAPLDKKDPSE
                     DKEDIEGNLLRPTGVALRGAHFCLKLFRAEDLPQMDDAVMDNVKQIFGFDSNKKNLVD
                     PFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRVMDWDRLTHNDTV
                     ATTYLGMSKISATGGEIEEEPAGVLKSPATDLDDNLGFLPTFGPCYVNLYGSPREFTG
                     FPDPYAELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKY
                     SLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDTTCLPLASTTQYSRAVFDGCHYYYL
                     PWGNVKPVVVLSSYWEDISHRVETQNQLLRIADRLEANLEQVHLALKAQCSSEDVDAL
                     VAQLTDELLADCSQPLCDIHEIPSATHLDQYLFRLRSRHLSQIKEAALALKLGHSELS
                     TALEQAEDWLLHLRALAEEPQNSLPDIIIWMLQGDKRVAYQRVPAHEVLFSRRGPSYC
                     GRNCGNLQTIFLKYPMEGMPGPRMPVQIRIKLWFGLSVDEKEFNQFAEGKLSVFAETY
                     ENQTKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWAWAGDWFVCPEKTLLH
                     DADAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEE
                     WSTDLNRAVDEQGWEYSITIPPDRKPKHWVPVEKMYYTHRRRRWVRLRRRDLSQMEAL
                     KKHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEG
                     ALGGMVDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYLYQARDLPAMDKDSF
                     SDPYAIVSFLHQSQKTVVEKNTLNPTWDQTLIFYEIEIFGEPASVAERPPSIVVELYD
                     HDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPAGELLAAFELIQREKPAIHHIP
                     GFEMHETSRILDELCAPAFFLQGLLQTTEDTDLPYPPPQREANIYMVPQNIKPALQRT
                     AIEILAWGLRNIKSYQMASVSSPSLVVECGGQTVQSCVIRNLRKNPNFDVCTLFMEVM
                     LPREDLYCPPIVVKVIDNRQFGRRPVVGQCTIRSLENFLCDPYSAESPSPQGGPDDVS
                     LLSPGEDVLIDIDDKEPLIPVQLADGLSSLGPTNLMPSPSSPHEEEFIDWWSKFFASI
                     GEREKCGSYLEKDFDTLKVYDTQLENVEAFGGLSDFCNTFKLYRGKTQEDTEDPSVIG
                     EFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIIRAFGLQPKDPNGKCDP
                     YIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI
                     GETVIDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYR
                     TDRVTFQDKEYTIQEIEAGRLPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQ
                     PDIEQGKLQMWIDIFPKVLGRPGPPFNITPRKARRFFLRCIIWNTKDVILDDLSLTGE
                     KMSDIYVKGWMVGFEEHKQKTDVHYRSLGGEGNFNWRFVFPFDYLPAEQVCAVAKKDA
                     FWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAEKCSLDQLDD
                     TFHPEWFVSLFEQKTVKGWWPCVTEEGAKKILAGKLEMTLEIVAESEHEERPAGQGRD
                     EPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRCAIILFIILFILLLFLGVFVY
                     AFPNYAAMKLVKPFR"
ORIGIN      
        1 agggggcccc tccgcctgcg ccttgaccct gcctctccag tttcgcgatg ctgcgagtct
       61 tcattctctt tgcggagaat gtccacaccc cggactccga catcagcgat gcttactgct
      121 ccgcggtgtt tgcaggggta aagaagagaa ccaaagtcat caagaacagt gtgaaccccg
      181 tgtggaatga gggctttgag tgggacctca aaggtattcc tctagaccag agctcagaac
      241 ttctcgtggt ggtcaaggac catgagacga tggggagaaa caggttcctg ggagaagcca
      301 agatcccact ccaggaggtc cttgccaccc ccagcctatc tgccagcttc aacgcacctc
      361 tgctggactc caagcagcaa cccacagggg cctctctggt cctgcaggta tcctacacac
      421 cgcccccagg agctgcgccc ttgttcccac cacccgcttc cctggcaccg tccccaacac
      481 tgcctgacat ggacctggtg gctggtgggg gacagagccg ggctgagact tggtccctgc
      541 tcagtgacag caccatggac acgagatatt ctgggaagaa gtggccagtc cccacggaca
      601 caggaggaga ggaagacacg gaagaccagg gcctgactgg agatgaagct gagctcttcc
      661 cagatccgag tgttgctgtg ggcccagggg gaccaacgac gcccaagaag ccaccttccc
      721 atcctcctcc ccactatcca ggggggaaaa ggaaaagaag ctctgctcca cctagaaagc
      781 tgctgtcaga caagccacag gacttccaga tcagagtcca ggtgattgag gggcgtcagc
      841 tgcctggggt gaacatcaag cctgtggtca aggtcacagc tgctgggcag accaagcgga
      901 ctcgaatcca gaagggaaat agcccacttt tcaatgagac tcttttcttc aacgtatttg
      961 actctccctt ggaactgttt gatgagccca tcttcatcac ggtggtagac tcacgctccc
     1021 tcaggacaga tgccctcctt ggcgagttcc ggatggatgt gggcaccgtg tacagagagc
     1081 cccgacatgc ttatctccgg aagtggctgc tgctctccga tcccgatgac ttctctgcag
     1141 gggccagagg ctacctcaaa gccagcctgt gtgtgctggg gcctggggac gaagctcccc
     1201 tagacaagaa agacccttct gaagacaaag aggacattga aggcaacctg cttaggccca
     1261 ctggtgtggc ccttcgtggt gcccattttt gcctgaagct cttccgggct gaggacttac
     1321 cacagatgga cgatgctgtg atggacaacg tcaagcaaat ctttggcttt gatagcaaca
     1381 agaagaacct ggtggacccc tttgtggaag tcagctttgc tgggaaaatg ctttgcagca
     1441 agatcctgga gaagactgct aaccctcagt ggaaccagaa catcacattg cctgcgatgt
     1501 ttccctctat gtgtgaaaaa atgaggattc gtgtcatgga ctgggaccgc ctcactcaca
     1561 atgacactgt ggctaccacc tacttgggta tgtcgaaaat ctctgccact ggaggagaaa
     1621 tagaagagga gcctgcaggt gtactcaaga gtccagccac tgacctggat gacaacctgg
     1681 gcttcctccc cacttttggg ccctgctatg tgaacctcta tggcagtccc cgagagttca
     1741 cgggcttccc agatccttat gcggagctca acacaggaaa gggagaaggt gtggcatata
     1801 ggggcaggct tctgttgtcc ctggagacca aactggtgga gcacagtgaa cagaaggtgg
     1861 aagaccttcc tgctgatgac atcttgagag tggagaagta cctgcggagg cgcaaatatt
     1921 ccctctttgc tgccttctac tcagccacaa tgctgcagga tgtggatgat gccatccagt
     1981 tcgaggtcag cattgggaac tacggaaaca agtttgacac cacctgcttg ccgttggcct
     2041 ctaccaccca atacagccgg gcagtctttg atggatgcca ctactattat ttgccctggg
     2101 gcaacgtgaa gcctgtggta gtactgtcct catactggga agacatcagc catcgagtcg
     2161 agactcagaa ccagctcctc aggatcgctg accgactgga agctaacctg gagcaagtcc
     2221 acctggctct gaaggcacag tgttcctctg aggatgtgga cgccctggtg gctcagttga
     2281 cagatgagct ccttgcagac tgcagccagc ccctgtgtga catccatgaa ataccttctg
     2341 ccacccacct tgatcagtac ctgttccgcc tccgctcccg tcacctgagc cagatcaaag
     2401 aagctgccct ggccttgaag cttggccaca gtgagctctc cactgccctg gagcaggccg
     2461 aggactggct tctgcatctc cgtgccctgg ctgaggagcc ccagaacagc ctgccagata
     2521 tcatcatctg gatgctgcag ggtgacaagc gtgtggccta ccaacgggtg cctgcccatg
     2581 aagtcctctt ctcccggcgg ggccccagct actgcggcag gaactgtggg aatctgcaga
     2641 ccatctttct gaaatatcct atggaaggca tgcctgggcc ccggatgccg gtgcagatcc
     2701 ggatcaagct ctggtttggg ctctcagtgg atgagaagga attcaatcag tttgcagagg
     2761 ggaagctctc tgtctttgct gaaacgtatg agaaccagac aaagctggcg ctggtcggga
     2821 actggggcac gacgggcctc acctacccca agttttctga cgtcacaggc aagatcaaac
     2881 taccgaagga tagcttccgc ccctcagctg gctgggcctg ggcaggagac tggttcgtgt
     2941 gtccagagaa gaccctgctc catgatgctg acgccggtca tctgagcttt gtggaggagg
     3001 tgtttgagaa ccagactcgg ctacctggag gccagtggat ctatatgagt gacaactaca
     3061 ccgacgtgaa tggggagaag gtgcttccaa aggacgatat tgaatgcccg ctgggttgga
     3121 agtgggaaga tgaagaatgg tccacagacc tcaatcgggc tgttgatgaa caaggctggg
     3181 agtacagcat caccataccc ccagaccgaa agcccaaaca ctgggtccct gttgagaaga
     3241 tgtattacac tcacaggcgt cgacgctggg tccgactgcg caggagggac ctcagccaga
     3301 tggaggcact gaagaagcac aggcaggcag aggctgaggg cgagggctgg gaatacgcct
     3361 ctctctttgg ctggaagttc cacctggagt accgcaagac agatgccttt cgccgccgcc
     3421 gctggcgccg ccgcatggag ccactggaga agacggggcc tgcagcggtg tttgcccttg
     3481 agggggccct gggcggcatg gtggatgaca agagcgaaga ttccatgtct gtgtctaccc
     3541 tgagctttgg cgttaacaga cccacaatct cctgcatctt tgactatggg aaccgctacc
     3601 atctgcgttg ctacctgtac caggcccggg acctgcccgc catggacaaa gactccttct
     3661 ctgatcccta tgccattgtc tccttcctgc atcaaagcca gaagacggtg gtggagaaga
     3721 acaccctgaa ccccacctgg gatcaaaccc tcatcttcta tgagatagag atctttggcg
     3781 agccggccag tgtcgccgag cggccaccca gcattgtggt ggagctgtat gaccatgaca
     3841 cctatggcgc tgacgagttc atgggccgct gtatttgtca gccaagcctg gaacggatgc
     3901 cccgcctggc ctggttccca ctgaccaggg gcagccagcc tgccggagag ctgctggcag
     3961 cgttcgagct tatccagaga gagaagccag ccatccatca catccctggc tttgagatgc
     4021 acgaaacttc aaggattttg gatgagctgt gcgctcctgc cttcttcctg cagggcctac
     4081 tccagacgac ggaggacaca gacttgcctt acccaccacc tcaaagggag gccaacatct
     4141 acatggttcc ccagaacatc aagccagctc tccagcgtac agccatcgag atcctggcct
     4201 ggggccttcg gaacataaag agctatcaga tggccagcgt gtcttccccc agcctcgtgg
     4261 tggagtgtgg tgggcagaca gtgcagtcct gtgtcatcag aaaccttcgg aagaacccca
     4321 actttgacgt ctgtactctg ttcatggaag tgatgttacc cagagaggac ctctactgtc
     4381 cccctattgt ggtcaaggtc attgataatc gccagtttgg ccgcaggcca gttgtgggtc
     4441 agtgcaccat tcgctccctg gagaacttcc tgtgtgaccc gtactcagca gagagtccat
     4501 ccccgcaagg tggcccagat gacgtgagct tactcagccc tggggaagac gtgctcattg
     4561 acattgatga caaggagcct ctcatccctg tccagcttgc agatgggctg tcaagcttgg
     4621 gccccactaa cctgatgcct tctccgtcca gtcctcatga ggaggagttc attgactggt
     4681 ggagcaaatt ctttgcttct atcggggaga gggaaaagtg tggttcctac ctggagaagg
     4741 attttgacac cctgaaggtc tatgacacac agctggagaa tgtggaggcc tttggaggcc
     4801 tgtccgactt ttgtaatacc ttcaagctct accggggcaa gactcaggag gacacagaag
     4861 atccatctgt catcggagaa tttaagggtc tcttcaaaat ttatcccctc ccagaagatc
     4921 cagccatccc tatgcccccg agacaattcc atcagctggc tgctcagggt ccccaggaat
     4981 gcttggtccg gatttacatc atccgagcat ttggcttaca gcccaaggac cccaatggca
     5041 agtgcgaccc ttacatcaag atctctatag ggaagaaatc agtgagtgac caggataact
     5101 acatcccttg taccctggag cctgtatttg gaaagatgtt tgaactcacc tgcactctac
     5161 ctctggagaa ggacttgaag atcacactct atgactatga cctgctctcc aaggatgaga
     5221 agattgggga gacagtcatt gatctggaga ataggctgct gtccaagttt ggggctcgct
     5281 gtggccttcc acagacctac tgtgtctctg gaccaaatca gtggagagat caactccgcc
     5341 cttcccagct cctccacctc ttctgccagc agcacagggt caaggccccc gtgtaccgga
     5401 cagaccgagt gacgtttcag gataaggaat acaccattca ggagatagag gctggcagac
     5461 tcccaaaccc acacctgggc ccggtggagg aacgcttagc cctgcatgtc cttcaacaac
     5521 aaggcttggt ccctgagcat gtggagtctc ggcctctgta cagtcctctg cagccagata
     5581 ttgagcaggg gaagctacag atgtggattg acatatttcc aaaggtgctg ggccggcctg
     5641 gacctccctt caacatcacc ccacggaaag ctcgaaggtt ttttctgcgt tgtattattt
     5701 ggaacacaaa agatgtgatc ttggatgacc tcagcctcac gggggagaag atgagtgaca
     5761 tctatgtgaa aggctggatg gtgggattcg aagaacacaa acagaagaca gatgtgcact
     5821 accgttccct gggcggggag ggcaatttca actggaggtt cgtgtttccc ttcgactatc
     5881 tgcccgctga gcaagtctgt gctgttgcca agaaggatgc tttctggaga ctcgacaaga
     5941 cagagagcaa gatcccagca cgtgtggtct tccagatttg ggacaatgac aagttctcct
     6001 ttgatgactt tctgggctcc ctgcagctgg atctcaaccg aatgcccaag ccagccaaga
     6061 cggctgagaa gtgctccttg gaccagctgg atgacacctt ccacccagaa tggtttgtgt
     6121 ccctttttga gcagaagaca gtgaaaggat ggtggccttg tgtgacagag gagggcgcga
     6181 agaagatcct ggcggggaag ctggaaatga ccttggagat cgttgcagaa agtgaacatg
     6241 aggagcggcc tgctggccag ggtcgggatg aacccaacat gaatccaaag ctagaagatc
     6301 ccaggcgccc tgacacctct ttcctgtggt tcacctcacc atacaagacc atgaagttca
     6361 tcttgtggcg acgattccgg tgtgccatca tcctcttcat catcctcttc atcctcctgc
     6421 tcttcctggg tgtctttgtc tacgccttcc cgaactatgc tgccatgaag ctggtgaagc
     6481 cctttagatg aagacatctg ctgtggagaa gggggcgcag gctgcctcct ggcccaggac
     6541 tagctgctcc tccattgctc tggggcctgg tggtcttgcg catgtccacg gagttcttgg
     6601 gatcacaccg ttttcatctt ctctttctcc cctaacccaa ctctcctctg gataaactct
     6661 tgactatctc agtataaagc agacagaacc tgagaatata tcactatgtg tctcca
//
