LOCUS       XM_006236770            6498 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dysferlin (Dysf), transcript variant
            X16, mRNA.
ACCESSION   XM_006236770
VERSION     XM_006236770.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006236770.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006236770.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6498
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6498
                     /gene="Dysf"
                     /note="dysferlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 25 ESTs, 1 long SRA read,
                     1 Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 29 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
     CDS             1..6273
                     /gene="Dysf"
                     /codon_start=1
                     /product="dysferlin isoform X16"
                     /protein_id="XP_006236832.1"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
                     /translation="MLCCLLARASNLPNVKKDRRSDPVASLIFRGVKKRTKVIKNSVN
                     PVWNEGFEWDLKGIPLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSLSASF
                     NAPLLDSKQQPTGASLVLQVSYTPPPGAAPLFPPPASLAPSPTLPDMDLVADTGGEED
                     TEDQGLTGDEAELFPDPSVAVGPGGPTTPKKPPSHPPPHYPGGKRKRSSAPPRKLLSD
                     KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIQKGNSPLFNETLFFNVFDS
                     PLELFDEPIFITVVDSRSLRTDALLGEFRMDVGTVYREPRHAYLRKWLLLSDPDDFSA
                     GARGYLKASLCVLGPGDEAPLDKKDPSEDKEDIEGNLLRPTGVALRGAHFCLKLFRAE
                     DLPQMDDAVMDNVKQIFGFDSNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNIT
                     LPAMFPSMCEKMRIRVMDWDRLTHNDTVATTYLGMSKISATGGEIEVDDNLGFLPTFG
                     PCYVNLYGSPREFTGFPDPYAELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPA
                     DDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDTTCLPLASTT
                     QYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRVETQNQLLRIADRLEANLEQVH
                     LALKAQCSSEDVDALVAQLTDELLADCSQPLCDIHEIPSATHLDQYLFRLRSRHLSQI
                     KEAALALKLGHSELSTALEQAEDWLLHLRALAEEPQNSLPDIIIWMLQGDKRVAYQRV
                     PAHEVLFSRRGPSYCGRNCGNLQTIFLKYPMEGMPGPRMPVQIRIKLWFGLSVDEKEF
                     NQFAEGKLSVFAETYENQTKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWA
                     WAGDWFVCPEKTLLHDADAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPK
                     DDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPDRKPKHWVPVEKMYYTHRRRR
                     WVRLRRRDLSQMEALKKHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRME
                     PLEKTGPAAVFALEGALGGMVDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCY
                     LYQARDLPAMDKDSFSDPYAIVSFLHQSQKTVVEKNTLNPTWDQTLIFYEIEIFGEPA
                     SVAERPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPAGELLAA
                     FELIQREKPAIHHIPGFEMHETSRILDETEDTDLPYPPPQREANIYMVPQNIKPALQR
                     TAIEILAWGLRNIKSYQMASVSSPSLVVECGGQTVQSCVIRNLRKNPNFDVCTLFMEV
                     MLPREDLYCPPIVVKVIDNRQFGRRPVVGQCTIRSLENFLCDPYSAESPSPQGGPDDV
                     SLLSPGEDVLIDIDDKEPLIPVQLADGLSSLGPTNLMPSPSSPHEEEFIDWWSKFFAS
                     IGEREKCGSYLEKDFDTLKVYDTQLENVEAFGGLSDFCNTFKLYRGKTQEDTEDPSVI
                     GEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIIRAFGLQPKDPNGKCD
                     PYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
                     IGETVIDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY
                     RTDRVTFQDKEYTIQEIEAGRLPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPL
                     QPDIEQGKLQMWIDIFPKVLGRPGPPFNITPRKARRFFLRCIIWNTKDVILDDLSLTG
                     EKMSDIYVKGWMVGFEEHKQKTDVHYRSLGGEGNFNWRFVFPFDYLPAEQVCAVAKKD
                     AFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAEKCSLDQLD
                     DTFHPEWFVSLFEQKTVKGWWPCVTEEGAKKILAGKLEMTLEIVAESEHEERPAGQGR
                     DEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRCAIILFIILFILLLFLGVFV
                     YAFPNYAAMKLVKPFR"
ORIGIN      
        1 atgctctgct gcctgctggc aagggccagc aacctcccca atgtgaagaa ggaccggcgc
       61 agtgaccctg ttgccagcct gatttttcga ggggtaaaga agagaaccaa agtcatcaag
      121 aacagtgtga accccgtgtg gaatgagggc tttgagtggg acctcaaagg tattcctcta
      181 gaccagagct cagaacttct cgtggtggtc aaggaccatg agacgatggg gagaaacagg
      241 ttcctgggag aagccaagat cccactccag gaggtccttg ccacccccag cctatctgcc
      301 agcttcaacg cacctctgct ggactccaag cagcaaccca caggggcctc tctggtcctg
      361 caggtatcct acacaccgcc cccaggagct gcgcccttgt tcccaccacc cgcttccctg
      421 gcaccgtccc caacactgcc tgacatggac ctggtggctg acacaggagg agaggaagac
      481 acggaagacc agggcctgac tggagatgaa gctgagctct tcccagatcc gagtgttgct
      541 gtgggcccag ggggaccaac gacgcccaag aagccacctt cccatcctcc tccccactat
      601 ccagggggga aaaggaaaag aagctctgct ccacctagaa agctgctgtc agacaagcca
      661 caggacttcc agatcagagt ccaggtgatt gaggggcgtc agctgcctgg ggtgaacatc
      721 aagcctgtgg tcaaggtcac agctgctggg cagaccaagc ggactcgaat ccagaaggga
      781 aatagcccac ttttcaatga gactcttttc ttcaacgtat ttgactctcc cttggaactg
      841 tttgatgagc ccatcttcat cacggtggta gactcacgct ccctcaggac agatgccctc
      901 cttggcgagt tccggatgga tgtgggcacc gtgtacagag agccccgaca tgcttatctc
      961 cggaagtggc tgctgctctc cgatcccgat gacttctctg caggggccag aggctacctc
     1021 aaagccagcc tgtgtgtgct ggggcctggg gacgaagctc ccctagacaa gaaagaccct
     1081 tctgaagaca aagaggacat tgaaggcaac ctgcttaggc ccactggtgt ggcccttcgt
     1141 ggtgcccatt tttgcctgaa gctcttccgg gctgaggact taccacagat ggacgatgct
     1201 gtgatggaca acgtcaagca aatctttggc tttgatagca acaagaagaa cctggtggac
     1261 ccctttgtgg aagtcagctt tgctgggaaa atgctttgca gcaagatcct ggagaagact
     1321 gctaaccctc agtggaacca gaacatcaca ttgcctgcga tgtttccctc tatgtgtgaa
     1381 aaaatgagga ttcgtgtcat ggactgggac cgcctcactc acaatgacac tgtggctacc
     1441 acctacttgg gtatgtcgaa aatctctgcc actggaggag aaatagaagt ggatgacaac
     1501 ctgggcttcc tccccacttt tgggccctgc tatgtgaacc tctatggcag tccccgagag
     1561 ttcacgggct tcccagatcc ttatgcggag ctcaacacag gaaagggaga aggtgtggca
     1621 tataggggca ggcttctgtt gtccctggag accaaactgg tggagcacag tgaacagaag
     1681 gtggaagacc ttcctgctga tgacatcttg agagtggaga agtacctgcg gaggcgcaaa
     1741 tattccctct ttgctgcctt ctactcagcc acaatgctgc aggatgtgga tgatgccatc
     1801 cagttcgagg tcagcattgg gaactacgga aacaagtttg acaccacctg cttgccgttg
     1861 gcctctacca cccaatacag ccgggcagtc tttgatggat gccactacta ttatttgccc
     1921 tggggcaacg tgaagcctgt ggtagtactg tcctcatact gggaagacat cagccatcga
     1981 gtcgagactc agaaccagct cctcaggatc gctgaccgac tggaagctaa cctggagcaa
     2041 gtccacctgg ctctgaaggc acagtgttcc tctgaggatg tggacgccct ggtggctcag
     2101 ttgacagatg agctccttgc agactgcagc cagcccctgt gtgacatcca tgaaatacct
     2161 tctgccaccc accttgatca gtacctgttc cgcctccgct cccgtcacct gagccagatc
     2221 aaagaagctg ccctggcctt gaagcttggc cacagtgagc tctccactgc cctggagcag
     2281 gccgaggact ggcttctgca tctccgtgcc ctggctgagg agccccagaa cagcctgcca
     2341 gatatcatca tctggatgct gcagggtgac aagcgtgtgg cctaccaacg ggtgcctgcc
     2401 catgaagtcc tcttctcccg gcggggcccc agctactgcg gcaggaactg tgggaatctg
     2461 cagaccatct ttctgaaata tcctatggaa ggcatgcctg ggccccggat gccggtgcag
     2521 atccggatca agctctggtt tgggctctca gtggatgaga aggaattcaa tcagtttgca
     2581 gaggggaagc tctctgtctt tgctgaaacg tatgagaacc agacaaagct ggcgctggtc
     2641 gggaactggg gcacgacggg cctcacctac cccaagtttt ctgacgtcac aggcaagatc
     2701 aaactaccga aggatagctt ccgcccctca gctggctggg cctgggcagg agactggttc
     2761 gtgtgtccag agaagaccct gctccatgat gctgacgccg gtcatctgag ctttgtggag
     2821 gaggtgtttg agaaccagac tcggctacct ggaggccagt ggatctatat gagtgacaac
     2881 tacaccgacg tgaatgggga gaaggtgctt ccaaaggacg atattgaatg cccgctgggt
     2941 tggaagtggg aagatgaaga atggtccaca gacctcaatc gggctgttga tgaacaaggc
     3001 tgggagtaca gcatcaccat acccccagac cgaaagccca aacactgggt ccctgttgag
     3061 aagatgtatt acactcacag gcgtcgacgc tgggtccgac tgcgcaggag ggacctcagc
     3121 cagatggagg cactgaagaa gcacaggcag gcagaggctg agggcgaggg ctgggaatac
     3181 gcctctctct ttggctggaa gttccacctg gagtaccgca agacagatgc ctttcgccgc
     3241 cgccgctggc gccgccgcat ggagccactg gagaagacgg ggcctgcagc ggtgtttgcc
     3301 cttgaggggg ccctgggcgg catggtggat gacaagagcg aagattccat gtctgtgtct
     3361 accctgagct ttggcgttaa cagacccaca atctcctgca tctttgacta tgggaaccgc
     3421 taccatctgc gttgctacct gtaccaggcc cgggacctgc ccgccatgga caaagactcc
     3481 ttctctgatc cctatgccat tgtctccttc ctgcatcaaa gccagaagac ggtggtggag
     3541 aagaacaccc tgaaccccac ctgggatcaa accctcatct tctatgagat agagatcttt
     3601 ggcgagccgg ccagtgtcgc cgagcggcca cccagcattg tggtggagct gtatgaccat
     3661 gacacctatg gcgctgacga gttcatgggc cgctgtattt gtcagccaag cctggaacgg
     3721 atgccccgcc tggcctggtt cccactgacc aggggcagcc agcctgccgg agagctgctg
     3781 gcagcgttcg agcttatcca gagagagaag ccagccatcc atcacatccc tggctttgag
     3841 atgcacgaaa cttcaaggat tttggatgag acggaggaca cagacttgcc ttacccacca
     3901 cctcaaaggg aggccaacat ctacatggtt ccccagaaca tcaagccagc tctccagcgt
     3961 acagccatcg agatcctggc ctggggcctt cggaacataa agagctatca gatggccagc
     4021 gtgtcttccc ccagcctcgt ggtggagtgt ggtgggcaga cagtgcagtc ctgtgtcatc
     4081 agaaaccttc ggaagaaccc caactttgac gtctgtactc tgttcatgga agtgatgtta
     4141 cccagagagg acctctactg tccccctatt gtggtcaagg tcattgataa tcgccagttt
     4201 ggccgcaggc cagttgtggg tcagtgcacc attcgctccc tggagaactt cctgtgtgac
     4261 ccgtactcag cagagagtcc atccccgcaa ggtggcccag atgacgtgag cttactcagc
     4321 cctggggaag acgtgctcat tgacattgat gacaaggagc ctctcatccc tgtccagctt
     4381 gcagatgggc tgtcaagctt gggccccact aacctgatgc cttctccgtc cagtcctcat
     4441 gaggaggagt tcattgactg gtggagcaaa ttctttgctt ctatcgggga gagggaaaag
     4501 tgtggttcct acctggagaa ggattttgac accctgaagg tctatgacac acagctggag
     4561 aatgtggagg cctttggagg cctgtccgac ttttgtaata ccttcaagct ctaccggggc
     4621 aagactcagg aggacacaga agatccatct gtcatcggag aatttaaggg tctcttcaaa
     4681 atttatcccc tcccagaaga tccagccatc cctatgcccc cgagacaatt ccatcagctg
     4741 gctgctcagg gtccccagga atgcttggtc cggatttaca tcatccgagc atttggctta
     4801 cagcccaagg accccaatgg caagtgcgac ccttacatca agatctctat agggaagaaa
     4861 tcagtgagtg accaggataa ctacatccct tgtaccctgg agcctgtatt tggaaagatg
     4921 tttgaactca cctgcactct acctctggag aaggacttga agatcacact ctatgactat
     4981 gacctgctct ccaaggatga gaagattggg gagacagtca ttgatctgga gaataggctg
     5041 ctgtccaagt ttggggctcg ctgtggcctt ccacagacct actgtgtctc tggaccaaat
     5101 cagtggagag atcaactccg cccttcccag ctcctccacc tcttctgcca gcagcacagg
     5161 gtcaaggccc ccgtgtaccg gacagaccga gtgacgtttc aggataagga atacaccatt
     5221 caggagatag aggctggcag actcccaaac ccacacctgg gcccggtgga ggaacgctta
     5281 gccctgcatg tccttcaaca acaaggcttg gtccctgagc atgtggagtc tcggcctctg
     5341 tacagtcctc tgcagccaga tattgagcag gggaagctac agatgtggat tgacatattt
     5401 ccaaaggtgc tgggccggcc tggacctccc ttcaacatca ccccacggaa agctcgaagg
     5461 ttttttctgc gttgtattat ttggaacaca aaagatgtga tcttggatga cctcagcctc
     5521 acgggggaga agatgagtga catctatgtg aaaggctgga tggtgggatt cgaagaacac
     5581 aaacagaaga cagatgtgca ctaccgttcc ctgggcgggg agggcaattt caactggagg
     5641 ttcgtgtttc ccttcgacta tctgcccgct gagcaagtct gtgctgttgc caagaaggat
     5701 gctttctgga gactcgacaa gacagagagc aagatcccag cacgtgtggt cttccagatt
     5761 tgggacaatg acaagttctc ctttgatgac tttctgggct ccctgcagct ggatctcaac
     5821 cgaatgccca agccagccaa gacggctgag aagtgctcct tggaccagct ggatgacacc
     5881 ttccacccag aatggtttgt gtcccttttt gagcagaaga cagtgaaagg atggtggcct
     5941 tgtgtgacag aggagggcgc gaagaagatc ctggcgggga agctggaaat gaccttggag
     6001 atcgttgcag aaagtgaaca tgaggagcgg cctgctggcc agggtcggga tgaacccaac
     6061 atgaatccaa agctagaaga tcccaggcgc cctgacacct ctttcctgtg gttcacctca
     6121 ccatacaaga ccatgaagtt catcttgtgg cgacgattcc ggtgtgccat catcctcttc
     6181 atcatcctct tcatcctcct gctcttcctg ggtgtctttg tctacgcctt cccgaactat
     6241 gctgccatga agctggtgaa gccctttaga tgaagacatc tgctgtggag aagggggcgc
     6301 aggctgcctc ctggcccagg actagctgct cctccattgc tctggggcct ggtggtcttg
     6361 cgcatgtcca cggagttctt gggatcacac cgttttcatc ttctctttct cccctaaccc
     6421 aactctcctc tggataaact cttgactatc tcagtataaa gcagacagaa cctgagaata
     6481 tatcactatg tgtctcca
//
