LOCUS       XM_006236769            6525 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dysferlin (Dysf), transcript variant
            X15, mRNA.
ACCESSION   XM_006236769
VERSION     XM_006236769.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006236769.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006236769.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6525
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6525
                     /gene="Dysf"
                     /note="dysferlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 27 ESTs, 1 long SRA read,
                     2 Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 31 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
     CDS             1..6300
                     /gene="Dysf"
                     /codon_start=1
                     /product="dysferlin isoform X15"
                     /protein_id="XP_006236831.1"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
                     /translation="MLRVFILFAENVHTPDSDISDAYCSAVFAGVKKRTKVIKNSVNP
                     VWNEGFEWDLKGIPLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSLSASFN
                     APLLDSKQQPTGASLVLQVSYTPPPGAAPLFPPPASLAPSPTLPDMDLVAGGGQSRAE
                     TWSLLSDSTMDTRYSGKKWPVPTDTGGEEDTEDQGLTGDEAELFPDPSVAVGPGGPTT
                     PKKPPSHPPPHYPGGKRKRSSAPPRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKV
                     TAAGQTKRTRIQKGNSPLFNETLFFNVFDSPLELFDEPIFITVVDSRSLRTDALLGEF
                     RMDVGTVYREPRHAYLRKWLLLSDPDDFSAGARGYLKASLCVLGPGDEAPLDKKDPSE
                     DKEDIEGNLLRPTGVALRGAHFCLKLFRAEDLPQMDDAVMDNVKQIFGFDSNKKNLVD
                     PFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRVMDWDRLTHNDTV
                     ATTYLGMSKISATGGEIEVDDNLGFLPTFGPCYVNLYGSPREFTGFPDPYAELNTGKG
                     EGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQ
                     DVDDAIQFEVSIGNYGNKFDTTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSS
                     YWEDISHRVETQNQLLRIADRLEANLEQVHLALKAQCSSEDVDALVAQLTDELLADCS
                     QPLCDIHEIPSATHLDQYLFRLRSRHLSQIKEAALALKLGHSELSTALEQAEDWLLHL
                     RALAEEPQNSLPDIIIWMLQGDKRVAYQRVPAHEVLFSRRGPSYCGRNCGNLQTIFLK
                     YPMEGMPGPRMPVQIRIKLWFGLSVDEKEFNQFAEGKLSVFAETYENQTKLALVGNWG
                     TTGLTYPKFSDVTGKIKLPKDSFRPSAGWAWAGDWFVCPEKTLLHDADAGHLSFVEEV
                     FENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQG
                     WEYSITIPPDRKPKHWVPVEKMYYTHRRRRWVRLRRRDLSQMEALKKHRQAEAEGEGW
                     EYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGMVDDKSEDS
                     MSVSTLSFGVNRPTISCIFDYGNRYHLRCYLYQARDLPAMDKDSFSDPYAIVSFLHQS
                     QKTVVEKNTLNPTWDQTLIFYEIEIFGEPASVAERPPSIVVELYDHDTYGADEFMGRC
                     ICQPSLERMPRLAWFPLTRGSQPAGELLAAFELIQREKPAIHHIPGFEMHETSRILDE
                     TEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNIKSYQMASVSSPSLVV
                     ECGGQTVQSCVIRNLRKNPNFDVCTLFMEVMLPREDLYCPPIVVKVIDNRQFGRRPVV
                     GQCTIRSLENFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPVQEEEFI
                     DWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFGGLSDFCNTFKLYRGKTQ
                     EDTEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIIRAFGLQ
                     PKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD
                     YDLLSKDEKIGETVIDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQ
                     QHRVKAPVYRTDRVTFQDKEYTIQEIEAGRLPNPHLGPVEERLALHVLQQQGLVPEHV
                     ESRPLYSPLQPDIEQGKLQMWIDIFPKVLGRPGPPFNITPRKARRFFLRCIIWNTKDV
                     ILDDLSLTGEKMSDIYVKGWMVGFEEHKQKTDVHYRSLGGEGNFNWRFVFPFDYLPAE
                     QVCAVAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA
                     EKCSLDQLDDTFHPEWFVSLFEQKTVKGWWPCVTEEGAKKILAGKLEMTLEIVAESEH
                     EERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRCAIILFIILFI
                     LLLFLGVFVYAFPNYAAMKLVKPFR"
ORIGIN      
        1 atgctgcgag tcttcattct ctttgcggag aatgtccaca ccccggactc cgacatcagc
       61 gatgcttact gctccgcggt gtttgcaggg gtaaagaaga gaaccaaagt catcaagaac
      121 agtgtgaacc ccgtgtggaa tgagggcttt gagtgggacc tcaaaggtat tcctctagac
      181 cagagctcag aacttctcgt ggtggtcaag gaccatgaga cgatggggag aaacaggttc
      241 ctgggagaag ccaagatccc actccaggag gtccttgcca cccccagcct atctgccagc
      301 ttcaacgcac ctctgctgga ctccaagcag caacccacag gggcctctct ggtcctgcag
      361 gtatcctaca caccgccccc aggagctgcg cccttgttcc caccacccgc ttccctggca
      421 ccgtccccaa cactgcctga catggacctg gtggctggtg ggggacagag ccgggctgag
      481 acttggtccc tgctcagtga cagcaccatg gacacgagat attctgggaa gaagtggcca
      541 gtccccacgg acacaggagg agaggaagac acggaagacc agggcctgac tggagatgaa
      601 gctgagctct tcccagatcc gagtgttgct gtgggcccag ggggaccaac gacgcccaag
      661 aagccacctt cccatcctcc tccccactat ccagggggga aaaggaaaag aagctctgct
      721 ccacctagaa agctgctgtc agacaagcca caggacttcc agatcagagt ccaggtgatt
      781 gaggggcgtc agctgcctgg ggtgaacatc aagcctgtgg tcaaggtcac agctgctggg
      841 cagaccaagc ggactcgaat ccagaaggga aatagcccac ttttcaatga gactcttttc
      901 ttcaacgtat ttgactctcc cttggaactg tttgatgagc ccatcttcat cacggtggta
      961 gactcacgct ccctcaggac agatgccctc cttggcgagt tccggatgga tgtgggcacc
     1021 gtgtacagag agccccgaca tgcttatctc cggaagtggc tgctgctctc cgatcccgat
     1081 gacttctctg caggggccag aggctacctc aaagccagcc tgtgtgtgct ggggcctggg
     1141 gacgaagctc ccctagacaa gaaagaccct tctgaagaca aagaggacat tgaaggcaac
     1201 ctgcttaggc ccactggtgt ggcccttcgt ggtgcccatt tttgcctgaa gctcttccgg
     1261 gctgaggact taccacagat ggacgatgct gtgatggaca acgtcaagca aatctttggc
     1321 tttgatagca acaagaagaa cctggtggac ccctttgtgg aagtcagctt tgctgggaaa
     1381 atgctttgca gcaagatcct ggagaagact gctaaccctc agtggaacca gaacatcaca
     1441 ttgcctgcga tgtttccctc tatgtgtgaa aaaatgagga ttcgtgtcat ggactgggac
     1501 cgcctcactc acaatgacac tgtggctacc acctacttgg gtatgtcgaa aatctctgcc
     1561 actggaggag aaatagaagt ggatgacaac ctgggcttcc tccccacttt tgggccctgc
     1621 tatgtgaacc tctatggcag tccccgagag ttcacgggct tcccagatcc ttatgcggag
     1681 ctcaacacag gaaagggaga aggtgtggca tataggggca ggcttctgtt gtccctggag
     1741 accaaactgg tggagcacag tgaacagaag gtggaagacc ttcctgctga tgacatcttg
     1801 agagtggaga agtacctgcg gaggcgcaaa tattccctct ttgctgcctt ctactcagcc
     1861 acaatgctgc aggatgtgga tgatgccatc cagttcgagg tcagcattgg gaactacgga
     1921 aacaagtttg acaccacctg cttgccgttg gcctctacca cccaatacag ccgggcagtc
     1981 tttgatggat gccactacta ttatttgccc tggggcaacg tgaagcctgt ggtagtactg
     2041 tcctcatact gggaagacat cagccatcga gtcgagactc agaaccagct cctcaggatc
     2101 gctgaccgac tggaagctaa cctggagcaa gtccacctgg ctctgaaggc acagtgttcc
     2161 tctgaggatg tggacgccct ggtggctcag ttgacagatg agctccttgc agactgcagc
     2221 cagcccctgt gtgacatcca tgaaatacct tctgccaccc accttgatca gtacctgttc
     2281 cgcctccgct cccgtcacct gagccagatc aaagaagctg ccctggcctt gaagcttggc
     2341 cacagtgagc tctccactgc cctggagcag gccgaggact ggcttctgca tctccgtgcc
     2401 ctggctgagg agccccagaa cagcctgcca gatatcatca tctggatgct gcagggtgac
     2461 aagcgtgtgg cctaccaacg ggtgcctgcc catgaagtcc tcttctcccg gcggggcccc
     2521 agctactgcg gcaggaactg tgggaatctg cagaccatct ttctgaaata tcctatggaa
     2581 ggcatgcctg ggccccggat gccggtgcag atccggatca agctctggtt tgggctctca
     2641 gtggatgaga aggaattcaa tcagtttgca gaggggaagc tctctgtctt tgctgaaacg
     2701 tatgagaacc agacaaagct ggcgctggtc gggaactggg gcacgacggg cctcacctac
     2761 cccaagtttt ctgacgtcac aggcaagatc aaactaccga aggatagctt ccgcccctca
     2821 gctggctggg cctgggcagg agactggttc gtgtgtccag agaagaccct gctccatgat
     2881 gctgacgccg gtcatctgag ctttgtggag gaggtgtttg agaaccagac tcggctacct
     2941 ggaggccagt ggatctatat gagtgacaac tacaccgacg tgaatgggga gaaggtgctt
     3001 ccaaaggacg atattgaatg cccgctgggt tggaagtggg aagatgaaga atggtccaca
     3061 gacctcaatc gggctgttga tgaacaaggc tgggagtaca gcatcaccat acccccagac
     3121 cgaaagccca aacactgggt ccctgttgag aagatgtatt acactcacag gcgtcgacgc
     3181 tgggtccgac tgcgcaggag ggacctcagc cagatggagg cactgaagaa gcacaggcag
     3241 gcagaggctg agggcgaggg ctgggaatac gcctctctct ttggctggaa gttccacctg
     3301 gagtaccgca agacagatgc ctttcgccgc cgccgctggc gccgccgcat ggagccactg
     3361 gagaagacgg ggcctgcagc ggtgtttgcc cttgaggggg ccctgggcgg catggtggat
     3421 gacaagagcg aagattccat gtctgtgtct accctgagct ttggcgttaa cagacccaca
     3481 atctcctgca tctttgacta tgggaaccgc taccatctgc gttgctacct gtaccaggcc
     3541 cgggacctgc ccgccatgga caaagactcc ttctctgatc cctatgccat tgtctccttc
     3601 ctgcatcaaa gccagaagac ggtggtggag aagaacaccc tgaaccccac ctgggatcaa
     3661 accctcatct tctatgagat agagatcttt ggcgagccgg ccagtgtcgc cgagcggcca
     3721 cccagcattg tggtggagct gtatgaccat gacacctatg gcgctgacga gttcatgggc
     3781 cgctgtattt gtcagccaag cctggaacgg atgccccgcc tggcctggtt cccactgacc
     3841 aggggcagcc agcctgccgg agagctgctg gcagcgttcg agcttatcca gagagagaag
     3901 ccagccatcc atcacatccc tggctttgag atgcacgaaa cttcaaggat tttggatgag
     3961 acggaggaca cagacttgcc ttacccacca cctcaaaggg aggccaacat ctacatggtt
     4021 ccccagaaca tcaagccagc tctccagcgt acagccatcg agatcctggc ctggggcctt
     4081 cggaacataa agagctatca gatggccagc gtgtcttccc ccagcctcgt ggtggagtgt
     4141 ggtgggcaga cagtgcagtc ctgtgtcatc agaaaccttc ggaagaaccc caactttgac
     4201 gtctgtactc tgttcatgga agtgatgtta cccagagagg acctctactg tccccctatt
     4261 gtggtcaagg tcattgataa tcgccagttt ggccgcaggc cagttgtggg tcagtgcacc
     4321 attcgctccc tggagaactt cctgtgtgac ccgtactcag cagagagtcc atccccgcaa
     4381 ggtggcccag atgacgtgag cttactcagc cctggggaag acgtgctcat tgacattgat
     4441 gacaaggagc ctctcatccc tgtccaggag gaggagttca ttgactggtg gagcaaattc
     4501 tttgcttcta tcggggagag ggaaaagtgt ggttcctacc tggagaagga ttttgacacc
     4561 ctgaaggtct atgacacaca gctggagaat gtggaggcct ttggaggcct gtccgacttt
     4621 tgtaatacct tcaagctcta ccggggcaag actcaggagg acacagaaga tccatctgtc
     4681 atcggagaat ttaagggtct cttcaaaatt tatcccctcc cagaagatcc agccatccct
     4741 atgcccccga gacaattcca tcagctggct gctcagggtc cccaggaatg cttggtccgg
     4801 atttacatca tccgagcatt tggcttacag cccaaggacc ccaatggcaa gtgcgaccct
     4861 tacatcaaga tctctatagg gaagaaatca gtgagtgacc aggataacta catcccttgt
     4921 accctggagc ctgtatttgg aaagatgttt gaactcacct gcactctacc tctggagaag
     4981 gacttgaaga tcacactcta tgactatgac ctgctctcca aggatgagaa gattggggag
     5041 acagtcattg atctggagaa taggctgctg tccaagtttg gggctcgctg tggccttcca
     5101 cagacctact gtgtctctgg accaaatcag tggagagatc aactccgccc ttcccagctc
     5161 ctccacctct tctgccagca gcacagggtc aaggcccccg tgtaccggac agaccgagtg
     5221 acgtttcagg ataaggaata caccattcag gagatagagg ctggcagact cccaaaccca
     5281 cacctgggcc cggtggagga acgcttagcc ctgcatgtcc ttcaacaaca aggcttggtc
     5341 cctgagcatg tggagtctcg gcctctgtac agtcctctgc agccagatat tgagcagggg
     5401 aagctacaga tgtggattga catatttcca aaggtgctgg gccggcctgg acctcccttc
     5461 aacatcaccc cacggaaagc tcgaaggttt tttctgcgtt gtattatttg gaacacaaaa
     5521 gatgtgatct tggatgacct cagcctcacg ggggagaaga tgagtgacat ctatgtgaaa
     5581 ggctggatgg tgggattcga agaacacaaa cagaagacag atgtgcacta ccgttccctg
     5641 ggcggggagg gcaatttcaa ctggaggttc gtgtttccct tcgactatct gcccgctgag
     5701 caagtctgtg ctgttgccaa gaaggatgct ttctggagac tcgacaagac agagagcaag
     5761 atcccagcac gtgtggtctt ccagatttgg gacaatgaca agttctcctt tgatgacttt
     5821 ctgggctccc tgcagctgga tctcaaccga atgcccaagc cagccaagac ggctgagaag
     5881 tgctccttgg accagctgga tgacaccttc cacccagaat ggtttgtgtc cctttttgag
     5941 cagaagacag tgaaaggatg gtggccttgt gtgacagagg agggcgcgaa gaagatcctg
     6001 gcggggaagc tggaaatgac cttggagatc gttgcagaaa gtgaacatga ggagcggcct
     6061 gctggccagg gtcgggatga acccaacatg aatccaaagc tagaagatcc caggcgccct
     6121 gacacctctt tcctgtggtt cacctcacca tacaagacca tgaagttcat cttgtggcga
     6181 cgattccggt gtgccatcat cctcttcatc atcctcttca tcctcctgct cttcctgggt
     6241 gtctttgtct acgccttccc gaactatgct gccatgaagc tggtgaagcc ctttagatga
     6301 agacatctgc tgtggagaag ggggcgcagg ctgcctcctg gcccaggact agctgctcct
     6361 ccattgctct ggggcctggt ggtcttgcgc atgtccacgg agttcttggg atcacaccgt
     6421 tttcatcttc tctttctccc ctaacccaac tctcctctgg ataaactctt gactatctca
     6481 gtataaagca gacagaacct gagaatatat cactatgtgt ctcca
//
