LOCUS       XM_006236768            6528 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dysferlin (Dysf), transcript variant
            X14, mRNA.
ACCESSION   XM_006236768
VERSION     XM_006236768.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006236768.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006236768.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6528
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6528
                     /gene="Dysf"
                     /note="dysferlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 27 ESTs, 1 long SRA read,
                     2 Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 44 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
     CDS             1..6303
                     /gene="Dysf"
                     /codon_start=1
                     /product="dysferlin isoform X14"
                     /protein_id="XP_006236830.1"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
                     /translation="MLCCLLARASNLPNVKKDRRSDPVASLIFRGVKKRTKVIKNSVN
                     PVWNEGFEWDLKGIPLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSLSASF
                     NAPLLDSKQQPTGASLVLQVSYTPPPGAAPLFPPPASLAPSPTLPDMDLVAGGGQSRA
                     ETWSLLSDSTMDTRYSGKKWPVPTDTGGEEDTEDQGLTGDEAELFPDPSVAVGPGGPT
                     TPKKPPSHPPPHYPGGKRKRSSAPPRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVK
                     VTAAGQTKRTRIQKGNSPLFNETLFFNVFDSPLELFDEPIFITVVDSRSLRTDALLGE
                     FRMDVGTVYREPRHAYLRKWLLLSDPDDFSAGARGYLKASLCVLGPGDEAPLDKKDPS
                     EDKEDIEGNLLRPTGVALRGAHFCLKLFRAEDLPQMDDAVMDNVKQIFGFDSNKKNLV
                     DPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRVMDWDRLTHNDT
                     VATTYLGMSKISATGGEIEVDDNLGFLPTFGPCYVNLYGSPREFTGFPDPYAELNTGK
                     GEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATML
                     QDVDDAIQFEVSIGNYGNKFDTTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLS
                     SYWEDISHRVETQNQLLRIADRLEANLEQVHLALKAQCSSEDVDALVAQLTDELLADC
                     SQPLCDIHEIPSATHLDQYLFRLRSRHLSQIKEAALALKLGHSELSTALEQAEDWLLH
                     LRALAEEPQNSLPDIIIWMLQGDKRVAYQRVPAHEVLFSRRGPSYCGRNCGNLQTIFL
                     KYPMEGMPGPRMPVQIRIKLWFGLSVDEKEFNQFAEGKLSVFAETYENQTKLALVGNW
                     GTTGLTYPKFSDVTGKIKLPKDSFRPSAGWAWAGDWFVCPEKTLLHDADAGHLSFVEE
                     VFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQ
                     GWEYSITIPPDRKPKHWVPVEKMYYTHRRRRWVRLRRRDLSQMEALKKHRQAEAEGEG
                     WEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGMVDDKSED
                     SMSVSTLSFGVNRPTISCIFDYGNRYHLRCYLYQARDLPAMDKDSFSDPYAIVSFLHQ
                     SQKTVVEKNTLNPTWDQTLIFYEIEIFGEPASVAERPPSIVVELYDHDTYGADEFMGR
                     CICQPSLERMPRLAWFPLTRGSQPAGELLAAFELIQREKPAIHHIPGFEMHETSRILD
                     ETEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNIKSYQMASVSSPSLV
                     VECGGQTVQSCVIRNLRKNPNFDVCTLFMEVMLPREDLYCPPIVVKVIDNRQFGRRPV
                     VGQCTIRSLENFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPVQEEEF
                     IDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFGGLSDFCNTFKLYRGKT
                     QEDTEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIIRAFGL
                     QPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
                     DYDLLSKDEKIGETVIDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFC
                     QQHRVKAPVYRTDRVTFQDKEYTIQEIEAGRLPNPHLGPVEERLALHVLQQQGLVPEH
                     VESRPLYSPLQPDIEQGKLQMWIDIFPKVLGRPGPPFNITPRKARRFFLRCIIWNTKD
                     VILDDLSLTGEKMSDIYVKGWMVGFEEHKQKTDVHYRSLGGEGNFNWRFVFPFDYLPA
                     EQVCAVAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKT
                     AEKCSLDQLDDTFHPEWFVSLFEQKTVKGWWPCVTEEGAKKILAGKLEMTLEIVAESE
                     HEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRCAIILFIILF
                     ILLLFLGVFVYAFPNYAAMKLVKPFR"
ORIGIN      
        1 atgctctgct gcctgctggc aagggccagc aacctcccca atgtgaagaa ggaccggcgc
       61 agtgaccctg ttgccagcct gatttttcga ggggtaaaga agagaaccaa agtcatcaag
      121 aacagtgtga accccgtgtg gaatgagggc tttgagtggg acctcaaagg tattcctcta
      181 gaccagagct cagaacttct cgtggtggtc aaggaccatg agacgatggg gagaaacagg
      241 ttcctgggag aagccaagat cccactccag gaggtccttg ccacccccag cctatctgcc
      301 agcttcaacg cacctctgct ggactccaag cagcaaccca caggggcctc tctggtcctg
      361 caggtatcct acacaccgcc cccaggagct gcgcccttgt tcccaccacc cgcttccctg
      421 gcaccgtccc caacactgcc tgacatggac ctggtggctg gtgggggaca gagccgggct
      481 gagacttggt ccctgctcag tgacagcacc atggacacga gatattctgg gaagaagtgg
      541 ccagtcccca cggacacagg aggagaggaa gacacggaag accagggcct gactggagat
      601 gaagctgagc tcttcccaga tccgagtgtt gctgtgggcc cagggggacc aacgacgccc
      661 aagaagccac cttcccatcc tcctccccac tatccagggg ggaaaaggaa aagaagctct
      721 gctccaccta gaaagctgct gtcagacaag ccacaggact tccagatcag agtccaggtg
      781 attgaggggc gtcagctgcc tggggtgaac atcaagcctg tggtcaaggt cacagctgct
      841 gggcagacca agcggactcg aatccagaag ggaaatagcc cacttttcaa tgagactctt
      901 ttcttcaacg tatttgactc tcccttggaa ctgtttgatg agcccatctt catcacggtg
      961 gtagactcac gctccctcag gacagatgcc ctccttggcg agttccggat ggatgtgggc
     1021 accgtgtaca gagagccccg acatgcttat ctccggaagt ggctgctgct ctccgatccc
     1081 gatgacttct ctgcaggggc cagaggctac ctcaaagcca gcctgtgtgt gctggggcct
     1141 ggggacgaag ctcccctaga caagaaagac ccttctgaag acaaagagga cattgaaggc
     1201 aacctgctta ggcccactgg tgtggccctt cgtggtgccc atttttgcct gaagctcttc
     1261 cgggctgagg acttaccaca gatggacgat gctgtgatgg acaacgtcaa gcaaatcttt
     1321 ggctttgata gcaacaagaa gaacctggtg gacccctttg tggaagtcag ctttgctggg
     1381 aaaatgcttt gcagcaagat cctggagaag actgctaacc ctcagtggaa ccagaacatc
     1441 acattgcctg cgatgtttcc ctctatgtgt gaaaaaatga ggattcgtgt catggactgg
     1501 gaccgcctca ctcacaatga cactgtggct accacctact tgggtatgtc gaaaatctct
     1561 gccactggag gagaaataga agtggatgac aacctgggct tcctccccac ttttgggccc
     1621 tgctatgtga acctctatgg cagtccccga gagttcacgg gcttcccaga tccttatgcg
     1681 gagctcaaca caggaaaggg agaaggtgtg gcatataggg gcaggcttct gttgtccctg
     1741 gagaccaaac tggtggagca cagtgaacag aaggtggaag accttcctgc tgatgacatc
     1801 ttgagagtgg agaagtacct gcggaggcgc aaatattccc tctttgctgc cttctactca
     1861 gccacaatgc tgcaggatgt ggatgatgcc atccagttcg aggtcagcat tgggaactac
     1921 ggaaacaagt ttgacaccac ctgcttgccg ttggcctcta ccacccaata cagccgggca
     1981 gtctttgatg gatgccacta ctattatttg ccctggggca acgtgaagcc tgtggtagta
     2041 ctgtcctcat actgggaaga catcagccat cgagtcgaga ctcagaacca gctcctcagg
     2101 atcgctgacc gactggaagc taacctggag caagtccacc tggctctgaa ggcacagtgt
     2161 tcctctgagg atgtggacgc cctggtggct cagttgacag atgagctcct tgcagactgc
     2221 agccagcccc tgtgtgacat ccatgaaata ccttctgcca cccaccttga tcagtacctg
     2281 ttccgcctcc gctcccgtca cctgagccag atcaaagaag ctgccctggc cttgaagctt
     2341 ggccacagtg agctctccac tgccctggag caggccgagg actggcttct gcatctccgt
     2401 gccctggctg aggagcccca gaacagcctg ccagatatca tcatctggat gctgcagggt
     2461 gacaagcgtg tggcctacca acgggtgcct gcccatgaag tcctcttctc ccggcggggc
     2521 cccagctact gcggcaggaa ctgtgggaat ctgcagacca tctttctgaa atatcctatg
     2581 gaaggcatgc ctgggccccg gatgccggtg cagatccgga tcaagctctg gtttgggctc
     2641 tcagtggatg agaaggaatt caatcagttt gcagagggga agctctctgt ctttgctgaa
     2701 acgtatgaga accagacaaa gctggcgctg gtcgggaact ggggcacgac gggcctcacc
     2761 taccccaagt tttctgacgt cacaggcaag atcaaactac cgaaggatag cttccgcccc
     2821 tcagctggct gggcctgggc aggagactgg ttcgtgtgtc cagagaagac cctgctccat
     2881 gatgctgacg ccggtcatct gagctttgtg gaggaggtgt ttgagaacca gactcggcta
     2941 cctggaggcc agtggatcta tatgagtgac aactacaccg acgtgaatgg ggagaaggtg
     3001 cttccaaagg acgatattga atgcccgctg ggttggaagt gggaagatga agaatggtcc
     3061 acagacctca atcgggctgt tgatgaacaa ggctgggagt acagcatcac cataccccca
     3121 gaccgaaagc ccaaacactg ggtccctgtt gagaagatgt attacactca caggcgtcga
     3181 cgctgggtcc gactgcgcag gagggacctc agccagatgg aggcactgaa gaagcacagg
     3241 caggcagagg ctgagggcga gggctgggaa tacgcctctc tctttggctg gaagttccac
     3301 ctggagtacc gcaagacaga tgcctttcgc cgccgccgct ggcgccgccg catggagcca
     3361 ctggagaaga cggggcctgc agcggtgttt gcccttgagg gggccctggg cggcatggtg
     3421 gatgacaaga gcgaagattc catgtctgtg tctaccctga gctttggcgt taacagaccc
     3481 acaatctcct gcatctttga ctatgggaac cgctaccatc tgcgttgcta cctgtaccag
     3541 gcccgggacc tgcccgccat ggacaaagac tccttctctg atccctatgc cattgtctcc
     3601 ttcctgcatc aaagccagaa gacggtggtg gagaagaaca ccctgaaccc cacctgggat
     3661 caaaccctca tcttctatga gatagagatc tttggcgagc cggccagtgt cgccgagcgg
     3721 ccacccagca ttgtggtgga gctgtatgac catgacacct atggcgctga cgagttcatg
     3781 ggccgctgta tttgtcagcc aagcctggaa cggatgcccc gcctggcctg gttcccactg
     3841 accaggggca gccagcctgc cggagagctg ctggcagcgt tcgagcttat ccagagagag
     3901 aagccagcca tccatcacat ccctggcttt gagatgcacg aaacttcaag gattttggat
     3961 gagacggagg acacagactt gccttaccca ccacctcaaa gggaggccaa catctacatg
     4021 gttccccaga acatcaagcc agctctccag cgtacagcca tcgagatcct ggcctggggc
     4081 cttcggaaca taaagagcta tcagatggcc agcgtgtctt cccccagcct cgtggtggag
     4141 tgtggtgggc agacagtgca gtcctgtgtc atcagaaacc ttcggaagaa ccccaacttt
     4201 gacgtctgta ctctgttcat ggaagtgatg ttacccagag aggacctcta ctgtccccct
     4261 attgtggtca aggtcattga taatcgccag tttggccgca ggccagttgt gggtcagtgc
     4321 accattcgct ccctggagaa cttcctgtgt gacccgtact cagcagagag tccatccccg
     4381 caaggtggcc cagatgacgt gagcttactc agccctgggg aagacgtgct cattgacatt
     4441 gatgacaagg agcctctcat ccctgtccag gaggaggagt tcattgactg gtggagcaaa
     4501 ttctttgctt ctatcgggga gagggaaaag tgtggttcct acctggagaa ggattttgac
     4561 accctgaagg tctatgacac acagctggag aatgtggagg cctttggagg cctgtccgac
     4621 ttttgtaata ccttcaagct ctaccggggc aagactcagg aggacacaga agatccatct
     4681 gtcatcggag aatttaaggg tctcttcaaa atttatcccc tcccagaaga tccagccatc
     4741 cctatgcccc cgagacaatt ccatcagctg gctgctcagg gtccccagga atgcttggtc
     4801 cggatttaca tcatccgagc atttggctta cagcccaagg accccaatgg caagtgcgac
     4861 ccttacatca agatctctat agggaagaaa tcagtgagtg accaggataa ctacatccct
     4921 tgtaccctgg agcctgtatt tggaaagatg tttgaactca cctgcactct acctctggag
     4981 aaggacttga agatcacact ctatgactat gacctgctct ccaaggatga gaagattggg
     5041 gagacagtca ttgatctgga gaataggctg ctgtccaagt ttggggctcg ctgtggcctt
     5101 ccacagacct actgtgtctc tggaccaaat cagtggagag atcaactccg cccttcccag
     5161 ctcctccacc tcttctgcca gcagcacagg gtcaaggccc ccgtgtaccg gacagaccga
     5221 gtgacgtttc aggataagga atacaccatt caggagatag aggctggcag actcccaaac
     5281 ccacacctgg gcccggtgga ggaacgctta gccctgcatg tccttcaaca acaaggcttg
     5341 gtccctgagc atgtggagtc tcggcctctg tacagtcctc tgcagccaga tattgagcag
     5401 gggaagctac agatgtggat tgacatattt ccaaaggtgc tgggccggcc tggacctccc
     5461 ttcaacatca ccccacggaa agctcgaagg ttttttctgc gttgtattat ttggaacaca
     5521 aaagatgtga tcttggatga cctcagcctc acgggggaga agatgagtga catctatgtg
     5581 aaaggctgga tggtgggatt cgaagaacac aaacagaaga cagatgtgca ctaccgttcc
     5641 ctgggcgggg agggcaattt caactggagg ttcgtgtttc ccttcgacta tctgcccgct
     5701 gagcaagtct gtgctgttgc caagaaggat gctttctgga gactcgacaa gacagagagc
     5761 aagatcccag cacgtgtggt cttccagatt tgggacaatg acaagttctc ctttgatgac
     5821 tttctgggct ccctgcagct ggatctcaac cgaatgccca agccagccaa gacggctgag
     5881 aagtgctcct tggaccagct ggatgacacc ttccacccag aatggtttgt gtcccttttt
     5941 gagcagaaga cagtgaaagg atggtggcct tgtgtgacag aggagggcgc gaagaagatc
     6001 ctggcgggga agctggaaat gaccttggag atcgttgcag aaagtgaaca tgaggagcgg
     6061 cctgctggcc agggtcggga tgaacccaac atgaatccaa agctagaaga tcccaggcgc
     6121 cctgacacct ctttcctgtg gttcacctca ccatacaaga ccatgaagtt catcttgtgg
     6181 cgacgattcc ggtgtgccat catcctcttc atcatcctct tcatcctcct gctcttcctg
     6241 ggtgtctttg tctacgcctt cccgaactat gctgccatga agctggtgaa gccctttaga
     6301 tgaagacatc tgctgtggag aagggggcgc aggctgcctc ctggcccagg actagctgct
     6361 cctccattgc tctggggcct ggtggtcttg cgcatgtcca cggagttctt gggatcacac
     6421 cgttttcatc ttctctttct cccctaaccc aactctcctc tggataaact cttgactatc
     6481 tcagtataaa gcagacagaa cctgagaata tatcactatg tgtctcca
//
