LOCUS       XM_006236767            6534 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dysferlin (Dysf), transcript variant
            X13, mRNA.
ACCESSION   XM_006236767
VERSION     XM_006236767.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006236767.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006236767.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6534
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6534
                     /gene="Dysf"
                     /note="dysferlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 25 ESTs, 1 long SRA read,
                     1 Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 19 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
     CDS             1..6309
                     /gene="Dysf"
                     /codon_start=1
                     /product="dysferlin isoform X13"
                     /protein_id="XP_006236829.1"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
                     /translation="MLRVFILFAENVHTPDSDISDAYCSAVFAGVKKRTKVIKNSVNP
                     VWNEGFEWDLKGIPLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSLSASFN
                     APLLDSKQQPTGASLVLQVSYTPPPGAAPLFPPPASLAPSPTLPDMDLVADTGGEEDT
                     EDQGLTGDEAELFPDPSVAVGPGGPTTPKKPPSHPPPHYPGGKRKRSSAPPRKLLSDK
                     PQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIQKGNSPLFNETLFFNVFDSP
                     LELFDEPIFITVVDSRSLRTDALLGEFRMDVGTVYREPRHAYLRKWLLLSDPDDFSAG
                     ARGYLKASLCVLGPGDEAPLDKKDPSEDKEDIEGNLLRPTGVALRGAHFCLKLFRAED
                     LPQMDDAVMDNVKQIFGFDSNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
                     PAMFPSMCEKMRIRVMDWDRLTHNDTVATTYLGMSKISATGGEIEEEPAGVLKSPATD
                     LDDNLGFLPTFGPCYVNLYGSPREFTGFPDPYAELNTGKGEGVAYRGRLLLSLETKLV
                     EHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNK
                     FDTTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRVETQNQLLRI
                     ADRLEANLEQVHLALKAQCSSEDVDALVAQLTDELLADCSQPLCDIHEIPSATHLDQY
                     LFRLRSRHLSQIKEAALALKLGHSELSTALEQAEDWLLHLRALAEEPQNSLPDIIIWM
                     LQGDKRVAYQRVPAHEVLFSRRGPSYCGRNCGNLQTIFLKYPMEGMPGPRMPVQIRIK
                     LWFGLSVDEKEFNQFAEGKLSVFAETYENQTKLALVGNWGTTGLTYPKFSDVTGKIKL
                     PKDSFRPSAGWAWAGDWFVCPEKTLLHDADAGHLSFVEEVFENQTRLPGGQWIYMSDN
                     YTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPDRKPKHWVP
                     VEKMYYTHRRRRWVRLRRRDLSQMEALKKHRQAEAEGEGWEYASLFGWKFHLEYRKTD
                     AFRRRRWRRRMEPLEKTGPAAVFALEGALGGMVDDKSEDSMSVSTLSFGVNRPTISCI
                     FDYGNRYHLRCYLYQARDLPAMDKDSFSDPYAIVSFLHQSQKTVVEKNTLNPTWDQTL
                     IFYEIEIFGEPASVAERPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPLT
                     RGSQPAGELLAAFELIQREKPAIHHIPGFEMHETSRILDETEDTDLPYPPPQREANIY
                     MVPQNIKPALQRTAIEILAWGLRNIKSYQMASVSSPSLVVECGGQTVQSCVIRNLRKN
                     PNFDVCTLFMEVMLPREDLYCPPIVVKVIDNRQFGRRPVVGQCTIRSLENFLCDPYSA
                     ESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPVQLADGLSSLGPTNLMPSPSSPHEE
                     EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFGGLSDFCNTFKLYRG
                     KTQEDTEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIIRAF
                     GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKIT
                     LYDYDLLSKDEKIGETVIDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHL
                     FCQQHRVKAPVYRTDRVTFQDKEYTIQEIEAGRLPNPHLGPVEERLALHVLQQQGLVP
                     EHVESRPLYSPLQPDIEQGKLQMWIDIFPKVLGRPGPPFNITPRKARRFFLRCIIWNT
                     KDVILDDLSLTGEKMSDIYVKGWMVGFEEHKQKTDVHYRSLGGEGNFNWRFVFPFDYL
                     PAEQVCAVAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPA
                     KTAEKCSLDQLDDTFHPEWFVSLFEQKTVKGWWPCVTEEGAKKILAGKLEMTLEIVAE
                     SEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRCAIILFII
                     LFILLLFLGVFVYAFPNYAAMKLVKPFR"
ORIGIN      
        1 atgctgcgag tcttcattct ctttgcggag aatgtccaca ccccggactc cgacatcagc
       61 gatgcttact gctccgcggt gtttgcaggg gtaaagaaga gaaccaaagt catcaagaac
      121 agtgtgaacc ccgtgtggaa tgagggcttt gagtgggacc tcaaaggtat tcctctagac
      181 cagagctcag aacttctcgt ggtggtcaag gaccatgaga cgatggggag aaacaggttc
      241 ctgggagaag ccaagatccc actccaggag gtccttgcca cccccagcct atctgccagc
      301 ttcaacgcac ctctgctgga ctccaagcag caacccacag gggcctctct ggtcctgcag
      361 gtatcctaca caccgccccc aggagctgcg cccttgttcc caccacccgc ttccctggca
      421 ccgtccccaa cactgcctga catggacctg gtggctgaca caggaggaga ggaagacacg
      481 gaagaccagg gcctgactgg agatgaagct gagctcttcc cagatccgag tgttgctgtg
      541 ggcccagggg gaccaacgac gcccaagaag ccaccttccc atcctcctcc ccactatcca
      601 ggggggaaaa ggaaaagaag ctctgctcca cctagaaagc tgctgtcaga caagccacag
      661 gacttccaga tcagagtcca ggtgattgag gggcgtcagc tgcctggggt gaacatcaag
      721 cctgtggtca aggtcacagc tgctgggcag accaagcgga ctcgaatcca gaagggaaat
      781 agcccacttt tcaatgagac tcttttcttc aacgtatttg actctccctt ggaactgttt
      841 gatgagccca tcttcatcac ggtggtagac tcacgctccc tcaggacaga tgccctcctt
      901 ggcgagttcc ggatggatgt gggcaccgtg tacagagagc cccgacatgc ttatctccgg
      961 aagtggctgc tgctctccga tcccgatgac ttctctgcag gggccagagg ctacctcaaa
     1021 gccagcctgt gtgtgctggg gcctggggac gaagctcccc tagacaagaa agacccttct
     1081 gaagacaaag aggacattga aggcaacctg cttaggccca ctggtgtggc ccttcgtggt
     1141 gcccattttt gcctgaagct cttccgggct gaggacttac cacagatgga cgatgctgtg
     1201 atggacaacg tcaagcaaat ctttggcttt gatagcaaca agaagaacct ggtggacccc
     1261 tttgtggaag tcagctttgc tgggaaaatg ctttgcagca agatcctgga gaagactgct
     1321 aaccctcagt ggaaccagaa catcacattg cctgcgatgt ttccctctat gtgtgaaaaa
     1381 atgaggattc gtgtcatgga ctgggaccgc ctcactcaca atgacactgt ggctaccacc
     1441 tacttgggta tgtcgaaaat ctctgccact ggaggagaaa tagaagagga gcctgcaggt
     1501 gtactcaaga gtccagccac tgacctggat gacaacctgg gcttcctccc cacttttggg
     1561 ccctgctatg tgaacctcta tggcagtccc cgagagttca cgggcttccc agatccttat
     1621 gcggagctca acacaggaaa gggagaaggt gtggcatata ggggcaggct tctgttgtcc
     1681 ctggagacca aactggtgga gcacagtgaa cagaaggtgg aagaccttcc tgctgatgac
     1741 atcttgagag tggagaagta cctgcggagg cgcaaatatt ccctctttgc tgccttctac
     1801 tcagccacaa tgctgcagga tgtggatgat gccatccagt tcgaggtcag cattgggaac
     1861 tacggaaaca agtttgacac cacctgcttg ccgttggcct ctaccaccca atacagccgg
     1921 gcagtctttg atggatgcca ctactattat ttgccctggg gcaacgtgaa gcctgtggta
     1981 gtactgtcct catactggga agacatcagc catcgagtcg agactcagaa ccagctcctc
     2041 aggatcgctg accgactgga agctaacctg gagcaagtcc acctggctct gaaggcacag
     2101 tgttcctctg aggatgtgga cgccctggtg gctcagttga cagatgagct ccttgcagac
     2161 tgcagccagc ccctgtgtga catccatgaa ataccttctg ccacccacct tgatcagtac
     2221 ctgttccgcc tccgctcccg tcacctgagc cagatcaaag aagctgccct ggccttgaag
     2281 cttggccaca gtgagctctc cactgccctg gagcaggccg aggactggct tctgcatctc
     2341 cgtgccctgg ctgaggagcc ccagaacagc ctgccagata tcatcatctg gatgctgcag
     2401 ggtgacaagc gtgtggccta ccaacgggtg cctgcccatg aagtcctctt ctcccggcgg
     2461 ggccccagct actgcggcag gaactgtggg aatctgcaga ccatctttct gaaatatcct
     2521 atggaaggca tgcctgggcc ccggatgccg gtgcagatcc ggatcaagct ctggtttggg
     2581 ctctcagtgg atgagaagga attcaatcag tttgcagagg ggaagctctc tgtctttgct
     2641 gaaacgtatg agaaccagac aaagctggcg ctggtcggga actggggcac gacgggcctc
     2701 acctacccca agttttctga cgtcacaggc aagatcaaac taccgaagga tagcttccgc
     2761 ccctcagctg gctgggcctg ggcaggagac tggttcgtgt gtccagagaa gaccctgctc
     2821 catgatgctg acgccggtca tctgagcttt gtggaggagg tgtttgagaa ccagactcgg
     2881 ctacctggag gccagtggat ctatatgagt gacaactaca ccgacgtgaa tggggagaag
     2941 gtgcttccaa aggacgatat tgaatgcccg ctgggttgga agtgggaaga tgaagaatgg
     3001 tccacagacc tcaatcgggc tgttgatgaa caaggctggg agtacagcat caccataccc
     3061 ccagaccgaa agcccaaaca ctgggtccct gttgagaaga tgtattacac tcacaggcgt
     3121 cgacgctggg tccgactgcg caggagggac ctcagccaga tggaggcact gaagaagcac
     3181 aggcaggcag aggctgaggg cgagggctgg gaatacgcct ctctctttgg ctggaagttc
     3241 cacctggagt accgcaagac agatgccttt cgccgccgcc gctggcgccg ccgcatggag
     3301 ccactggaga agacggggcc tgcagcggtg tttgcccttg agggggccct gggcggcatg
     3361 gtggatgaca agagcgaaga ttccatgtct gtgtctaccc tgagctttgg cgttaacaga
     3421 cccacaatct cctgcatctt tgactatggg aaccgctacc atctgcgttg ctacctgtac
     3481 caggcccggg acctgcccgc catggacaaa gactccttct ctgatcccta tgccattgtc
     3541 tccttcctgc atcaaagcca gaagacggtg gtggagaaga acaccctgaa ccccacctgg
     3601 gatcaaaccc tcatcttcta tgagatagag atctttggcg agccggccag tgtcgccgag
     3661 cggccaccca gcattgtggt ggagctgtat gaccatgaca cctatggcgc tgacgagttc
     3721 atgggccgct gtatttgtca gccaagcctg gaacggatgc cccgcctggc ctggttccca
     3781 ctgaccaggg gcagccagcc tgccggagag ctgctggcag cgttcgagct tatccagaga
     3841 gagaagccag ccatccatca catccctggc tttgagatgc acgaaacttc aaggattttg
     3901 gatgagacgg aggacacaga cttgccttac ccaccacctc aaagggaggc caacatctac
     3961 atggttcccc agaacatcaa gccagctctc cagcgtacag ccatcgagat cctggcctgg
     4021 ggccttcgga acataaagag ctatcagatg gccagcgtgt cttcccccag cctcgtggtg
     4081 gagtgtggtg ggcagacagt gcagtcctgt gtcatcagaa accttcggaa gaaccccaac
     4141 tttgacgtct gtactctgtt catggaagtg atgttaccca gagaggacct ctactgtccc
     4201 cctattgtgg tcaaggtcat tgataatcgc cagtttggcc gcaggccagt tgtgggtcag
     4261 tgcaccattc gctccctgga gaacttcctg tgtgacccgt actcagcaga gagtccatcc
     4321 ccgcaaggtg gcccagatga cgtgagctta ctcagccctg gggaagacgt gctcattgac
     4381 attgatgaca aggagcctct catccctgtc cagcttgcag atgggctgtc aagcttgggc
     4441 cccactaacc tgatgccttc tccgtccagt cctcatgagg aggagttcat tgactggtgg
     4501 agcaaattct ttgcttctat cggggagagg gaaaagtgtg gttcctacct ggagaaggat
     4561 tttgacaccc tgaaggtcta tgacacacag ctggagaatg tggaggcctt tggaggcctg
     4621 tccgactttt gtaatacctt caagctctac cggggcaaga ctcaggagga cacagaagat
     4681 ccatctgtca tcggagaatt taagggtctc ttcaaaattt atcccctccc agaagatcca
     4741 gccatcccta tgcccccgag acaattccat cagctggctg ctcagggtcc ccaggaatgc
     4801 ttggtccgga tttacatcat ccgagcattt ggcttacagc ccaaggaccc caatggcaag
     4861 tgcgaccctt acatcaagat ctctataggg aagaaatcag tgagtgacca ggataactac
     4921 atcccttgta ccctggagcc tgtatttgga aagatgtttg aactcacctg cactctacct
     4981 ctggagaagg acttgaagat cacactctat gactatgacc tgctctccaa ggatgagaag
     5041 attggggaga cagtcattga tctggagaat aggctgctgt ccaagtttgg ggctcgctgt
     5101 ggccttccac agacctactg tgtctctgga ccaaatcagt ggagagatca actccgccct
     5161 tcccagctcc tccacctctt ctgccagcag cacagggtca aggcccccgt gtaccggaca
     5221 gaccgagtga cgtttcagga taaggaatac accattcagg agatagaggc tggcagactc
     5281 ccaaacccac acctgggccc ggtggaggaa cgcttagccc tgcatgtcct tcaacaacaa
     5341 ggcttggtcc ctgagcatgt ggagtctcgg cctctgtaca gtcctctgca gccagatatt
     5401 gagcagggga agctacagat gtggattgac atatttccaa aggtgctggg ccggcctgga
     5461 cctcccttca acatcacccc acggaaagct cgaaggtttt ttctgcgttg tattatttgg
     5521 aacacaaaag atgtgatctt ggatgacctc agcctcacgg gggagaagat gagtgacatc
     5581 tatgtgaaag gctggatggt gggattcgaa gaacacaaac agaagacaga tgtgcactac
     5641 cgttccctgg gcggggaggg caatttcaac tggaggttcg tgtttccctt cgactatctg
     5701 cccgctgagc aagtctgtgc tgttgccaag aaggatgctt tctggagact cgacaagaca
     5761 gagagcaaga tcccagcacg tgtggtcttc cagatttggg acaatgacaa gttctccttt
     5821 gatgactttc tgggctccct gcagctggat ctcaaccgaa tgcccaagcc agccaagacg
     5881 gctgagaagt gctccttgga ccagctggat gacaccttcc acccagaatg gtttgtgtcc
     5941 ctttttgagc agaagacagt gaaaggatgg tggccttgtg tgacagagga gggcgcgaag
     6001 aagatcctgg cggggaagct ggaaatgacc ttggagatcg ttgcagaaag tgaacatgag
     6061 gagcggcctg ctggccaggg tcgggatgaa cccaacatga atccaaagct agaagatccc
     6121 aggcgccctg acacctcttt cctgtggttc acctcaccat acaagaccat gaagttcatc
     6181 ttgtggcgac gattccggtg tgccatcatc ctcttcatca tcctcttcat cctcctgctc
     6241 ttcctgggtg tctttgtcta cgccttcccg aactatgctg ccatgaagct ggtgaagccc
     6301 tttagatgaa gacatctgct gtggagaagg gggcgcaggc tgcctcctgg cccaggacta
     6361 gctgctcctc cattgctctg gggcctggtg gtcttgcgca tgtccacgga gttcttggga
     6421 tcacaccgtt ttcatcttct ctttctcccc taacccaact ctcctctgga taaactcttg
     6481 actatctcag tataaagcag acagaacctg agaatatatc actatgtgtc tcca
//
