LOCUS       XM_006236760            6591 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus dysferlin (Dysf), transcript variant
            X6, mRNA.
ACCESSION   XM_006236760
VERSION     XM_006236760.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006236760.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006236760.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6591
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6591
                     /gene="Dysf"
                     /note="dysferlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 25 ESTs, 1 long SRA read,
                     1 Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 44 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
     CDS             1..6366
                     /gene="Dysf"
                     /codon_start=1
                     /product="dysferlin isoform X6"
                     /protein_id="XP_006236822.1"
                     /db_xref="GeneID:312492"
                     /db_xref="RGD:1311023"
                     /translation="MLCCLLARASNLPNVKKDRRSDPVASLIFRGVKKRTKVIKNSVN
                     PVWNEGFEWDLKGIPLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSLSASF
                     NAPLLDSKQQPTGASLVLQVSYTPPPGAAPLFPPPASLAPSPTLPDMDLVAGGGQSRA
                     ETWSLLSDSTMDTRYSGKKWPVPTDTGGEEDTEDQGLTGDEAELFPDPSVAVGPGGPT
                     TPKKPPSHPPPHYPGGKRKRSSAPPRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVK
                     VTAAGQTKRTRIQKGNSPLFNETLFFNVFDSPLELFDEPIFITVVDSRSLRTDALLGE
                     FRMDVGTVYREPRHAYLRKWLLLSDPDDFSAGARGYLKASLCVLGPGDEAPLDKKDPS
                     EDKEDIEGNLLRPTGVALRGAHFCLKLFRAEDLPQMDDAVMDNVKQIFGFDSNKKNLV
                     DPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRVMDWDRLTHNDT
                     VATTYLGMSKISATGGEIEVDDNLGFLPTFGPCYVNLYGSPREFTGFPDPYAELNTGK
                     GEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATML
                     QDVDDAIQFEVSIGNYGNKFDTTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLS
                     SYWEDISHRVETQNQLLRIADRLEANLEQVHLALKAQCSSEDVDALVAQLTDELLADC
                     SQPLCDIHEIPSATHLDQYLFRLRSRHLSQIKEAALALKLGHSELSTALEQAEDWLLH
                     LRALAEEPQNSLPDIIIWMLQGDKRVAYQRVPAHEVLFSRRGPSYCGRNCGNLQTIFL
                     KYPMEGMPGPRMPVQIRIKLWFGLSVDEKEFNQFAEGKLSVFAETYENQTKLALVGNW
                     GTTGLTYPKFSDVTGKIKLPKDSFRPSAGWAWAGDWFVCPEKTLLHDADAGHLSFVEE
                     VFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQ
                     GWEYSITIPPDRKPKHWVPVEKMYYTHRRRRWVRLRRRDLSQMEALKKHRQAEAEGEG
                     WEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGMVDDKSED
                     SMSVSTLSFGVNRPTISCIFDYGNRYHLRCYLYQARDLPAMDKDSFSDPYAIVSFLHQ
                     SQKTVVEKNTLNPTWDQTLIFYEIEIFGEPASVAERPPSIVVELYDHDTYGADEFMGR
                     CICQPSLERMPRLAWFPLTRGSQPAGELLAAFELIQREKPAIHHIPGFEMHETSRILD
                     ETEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNIKSYQMASVSSPSLV
                     VECGGQTVQSCVIRNLRKNPNFDVCTLFMEVMLPREDLYCPPIVVKVIDNRQFGRRPV
                     VGQCTIRSLENFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPVQLADG
                     LSSLGPTNLMPSPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLEN
                     VEAFGGLSDFCNTFKLYRGKTQEDTEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQ
                     LAAQGPQECLVRIYIIRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
                     GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVIDLENRLLSKFGARCGLPQTYC
                     VSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVTFQDKEYTIQEIEAGRLPNPHL
                     GPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWIDIFPKVLGRPGPPF
                     NITPRKARRFFLRCIIWNTKDVILDDLSLTGEKMSDIYVKGWMVGFEEHKQKTDVHYR
                     SLGGEGNFNWRFVFPFDYLPAEQVCAVAKKDAFWRLDKTESKIPARVVFQIWDNDKFS
                     FDDFLGSLQLDLNRMPKPAKTAEKCSLDQLDDTFHPEWFVSLFEQKTVKGWWPCVTEE
                     GAKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYK
                     TMKFILWRRFRCAIILFIILFILLLFLGVFVYAFPNYAAMKLVKPFR"
ORIGIN      
        1 atgctctgct gcctgctggc aagggccagc aacctcccca atgtgaagaa ggaccggcgc
       61 agtgaccctg ttgccagcct gatttttcga ggggtaaaga agagaaccaa agtcatcaag
      121 aacagtgtga accccgtgtg gaatgagggc tttgagtggg acctcaaagg tattcctcta
      181 gaccagagct cagaacttct cgtggtggtc aaggaccatg agacgatggg gagaaacagg
      241 ttcctgggag aagccaagat cccactccag gaggtccttg ccacccccag cctatctgcc
      301 agcttcaacg cacctctgct ggactccaag cagcaaccca caggggcctc tctggtcctg
      361 caggtatcct acacaccgcc cccaggagct gcgcccttgt tcccaccacc cgcttccctg
      421 gcaccgtccc caacactgcc tgacatggac ctggtggctg gtgggggaca gagccgggct
      481 gagacttggt ccctgctcag tgacagcacc atggacacga gatattctgg gaagaagtgg
      541 ccagtcccca cggacacagg aggagaggaa gacacggaag accagggcct gactggagat
      601 gaagctgagc tcttcccaga tccgagtgtt gctgtgggcc cagggggacc aacgacgccc
      661 aagaagccac cttcccatcc tcctccccac tatccagggg ggaaaaggaa aagaagctct
      721 gctccaccta gaaagctgct gtcagacaag ccacaggact tccagatcag agtccaggtg
      781 attgaggggc gtcagctgcc tggggtgaac atcaagcctg tggtcaaggt cacagctgct
      841 gggcagacca agcggactcg aatccagaag ggaaatagcc cacttttcaa tgagactctt
      901 ttcttcaacg tatttgactc tcccttggaa ctgtttgatg agcccatctt catcacggtg
      961 gtagactcac gctccctcag gacagatgcc ctccttggcg agttccggat ggatgtgggc
     1021 accgtgtaca gagagccccg acatgcttat ctccggaagt ggctgctgct ctccgatccc
     1081 gatgacttct ctgcaggggc cagaggctac ctcaaagcca gcctgtgtgt gctggggcct
     1141 ggggacgaag ctcccctaga caagaaagac ccttctgaag acaaagagga cattgaaggc
     1201 aacctgctta ggcccactgg tgtggccctt cgtggtgccc atttttgcct gaagctcttc
     1261 cgggctgagg acttaccaca gatggacgat gctgtgatgg acaacgtcaa gcaaatcttt
     1321 ggctttgata gcaacaagaa gaacctggtg gacccctttg tggaagtcag ctttgctggg
     1381 aaaatgcttt gcagcaagat cctggagaag actgctaacc ctcagtggaa ccagaacatc
     1441 acattgcctg cgatgtttcc ctctatgtgt gaaaaaatga ggattcgtgt catggactgg
     1501 gaccgcctca ctcacaatga cactgtggct accacctact tgggtatgtc gaaaatctct
     1561 gccactggag gagaaataga agtggatgac aacctgggct tcctccccac ttttgggccc
     1621 tgctatgtga acctctatgg cagtccccga gagttcacgg gcttcccaga tccttatgcg
     1681 gagctcaaca caggaaaggg agaaggtgtg gcatataggg gcaggcttct gttgtccctg
     1741 gagaccaaac tggtggagca cagtgaacag aaggtggaag accttcctgc tgatgacatc
     1801 ttgagagtgg agaagtacct gcggaggcgc aaatattccc tctttgctgc cttctactca
     1861 gccacaatgc tgcaggatgt ggatgatgcc atccagttcg aggtcagcat tgggaactac
     1921 ggaaacaagt ttgacaccac ctgcttgccg ttggcctcta ccacccaata cagccgggca
     1981 gtctttgatg gatgccacta ctattatttg ccctggggca acgtgaagcc tgtggtagta
     2041 ctgtcctcat actgggaaga catcagccat cgagtcgaga ctcagaacca gctcctcagg
     2101 atcgctgacc gactggaagc taacctggag caagtccacc tggctctgaa ggcacagtgt
     2161 tcctctgagg atgtggacgc cctggtggct cagttgacag atgagctcct tgcagactgc
     2221 agccagcccc tgtgtgacat ccatgaaata ccttctgcca cccaccttga tcagtacctg
     2281 ttccgcctcc gctcccgtca cctgagccag atcaaagaag ctgccctggc cttgaagctt
     2341 ggccacagtg agctctccac tgccctggag caggccgagg actggcttct gcatctccgt
     2401 gccctggctg aggagcccca gaacagcctg ccagatatca tcatctggat gctgcagggt
     2461 gacaagcgtg tggcctacca acgggtgcct gcccatgaag tcctcttctc ccggcggggc
     2521 cccagctact gcggcaggaa ctgtgggaat ctgcagacca tctttctgaa atatcctatg
     2581 gaaggcatgc ctgggccccg gatgccggtg cagatccgga tcaagctctg gtttgggctc
     2641 tcagtggatg agaaggaatt caatcagttt gcagagggga agctctctgt ctttgctgaa
     2701 acgtatgaga accagacaaa gctggcgctg gtcgggaact ggggcacgac gggcctcacc
     2761 taccccaagt tttctgacgt cacaggcaag atcaaactac cgaaggatag cttccgcccc
     2821 tcagctggct gggcctgggc aggagactgg ttcgtgtgtc cagagaagac cctgctccat
     2881 gatgctgacg ccggtcatct gagctttgtg gaggaggtgt ttgagaacca gactcggcta
     2941 cctggaggcc agtggatcta tatgagtgac aactacaccg acgtgaatgg ggagaaggtg
     3001 cttccaaagg acgatattga atgcccgctg ggttggaagt gggaagatga agaatggtcc
     3061 acagacctca atcgggctgt tgatgaacaa ggctgggagt acagcatcac cataccccca
     3121 gaccgaaagc ccaaacactg ggtccctgtt gagaagatgt attacactca caggcgtcga
     3181 cgctgggtcc gactgcgcag gagggacctc agccagatgg aggcactgaa gaagcacagg
     3241 caggcagagg ctgagggcga gggctgggaa tacgcctctc tctttggctg gaagttccac
     3301 ctggagtacc gcaagacaga tgcctttcgc cgccgccgct ggcgccgccg catggagcca
     3361 ctggagaaga cggggcctgc agcggtgttt gcccttgagg gggccctggg cggcatggtg
     3421 gatgacaaga gcgaagattc catgtctgtg tctaccctga gctttggcgt taacagaccc
     3481 acaatctcct gcatctttga ctatgggaac cgctaccatc tgcgttgcta cctgtaccag
     3541 gcccgggacc tgcccgccat ggacaaagac tccttctctg atccctatgc cattgtctcc
     3601 ttcctgcatc aaagccagaa gacggtggtg gagaagaaca ccctgaaccc cacctgggat
     3661 caaaccctca tcttctatga gatagagatc tttggcgagc cggccagtgt cgccgagcgg
     3721 ccacccagca ttgtggtgga gctgtatgac catgacacct atggcgctga cgagttcatg
     3781 ggccgctgta tttgtcagcc aagcctggaa cggatgcccc gcctggcctg gttcccactg
     3841 accaggggca gccagcctgc cggagagctg ctggcagcgt tcgagcttat ccagagagag
     3901 aagccagcca tccatcacat ccctggcttt gagatgcacg aaacttcaag gattttggat
     3961 gagacggagg acacagactt gccttaccca ccacctcaaa gggaggccaa catctacatg
     4021 gttccccaga acatcaagcc agctctccag cgtacagcca tcgagatcct ggcctggggc
     4081 cttcggaaca taaagagcta tcagatggcc agcgtgtctt cccccagcct cgtggtggag
     4141 tgtggtgggc agacagtgca gtcctgtgtc atcagaaacc ttcggaagaa ccccaacttt
     4201 gacgtctgta ctctgttcat ggaagtgatg ttacccagag aggacctcta ctgtccccct
     4261 attgtggtca aggtcattga taatcgccag tttggccgca ggccagttgt gggtcagtgc
     4321 accattcgct ccctggagaa cttcctgtgt gacccgtact cagcagagag tccatccccg
     4381 caaggtggcc cagatgacgt gagcttactc agccctgggg aagacgtgct cattgacatt
     4441 gatgacaagg agcctctcat ccctgtccag cttgcagatg ggctgtcaag cttgggcccc
     4501 actaacctga tgccttctcc gtccagtcct catgaggagg agttcattga ctggtggagc
     4561 aaattctttg cttctatcgg ggagagggaa aagtgtggtt cctacctgga gaaggatttt
     4621 gacaccctga aggtctatga cacacagctg gagaatgtgg aggcctttgg aggcctgtcc
     4681 gacttttgta ataccttcaa gctctaccgg ggcaagactc aggaggacac agaagatcca
     4741 tctgtcatcg gagaatttaa gggtctcttc aaaatttatc ccctcccaga agatccagcc
     4801 atccctatgc ccccgagaca attccatcag ctggctgctc agggtcccca ggaatgcttg
     4861 gtccggattt acatcatccg agcatttggc ttacagccca aggaccccaa tggcaagtgc
     4921 gacccttaca tcaagatctc tatagggaag aaatcagtga gtgaccagga taactacatc
     4981 ccttgtaccc tggagcctgt atttggaaag atgtttgaac tcacctgcac tctacctctg
     5041 gagaaggact tgaagatcac actctatgac tatgacctgc tctccaagga tgagaagatt
     5101 ggggagacag tcattgatct ggagaatagg ctgctgtcca agtttggggc tcgctgtggc
     5161 cttccacaga cctactgtgt ctctggacca aatcagtgga gagatcaact ccgcccttcc
     5221 cagctcctcc acctcttctg ccagcagcac agggtcaagg cccccgtgta ccggacagac
     5281 cgagtgacgt ttcaggataa ggaatacacc attcaggaga tagaggctgg cagactccca
     5341 aacccacacc tgggcccggt ggaggaacgc ttagccctgc atgtccttca acaacaaggc
     5401 ttggtccctg agcatgtgga gtctcggcct ctgtacagtc ctctgcagcc agatattgag
     5461 caggggaagc tacagatgtg gattgacata tttccaaagg tgctgggccg gcctggacct
     5521 cccttcaaca tcaccccacg gaaagctcga aggttttttc tgcgttgtat tatttggaac
     5581 acaaaagatg tgatcttgga tgacctcagc ctcacggggg agaagatgag tgacatctat
     5641 gtgaaaggct ggatggtggg attcgaagaa cacaaacaga agacagatgt gcactaccgt
     5701 tccctgggcg gggagggcaa tttcaactgg aggttcgtgt ttcccttcga ctatctgccc
     5761 gctgagcaag tctgtgctgt tgccaagaag gatgctttct ggagactcga caagacagag
     5821 agcaagatcc cagcacgtgt ggtcttccag atttgggaca atgacaagtt ctcctttgat
     5881 gactttctgg gctccctgca gctggatctc aaccgaatgc ccaagccagc caagacggct
     5941 gagaagtgct ccttggacca gctggatgac accttccacc cagaatggtt tgtgtccctt
     6001 tttgagcaga agacagtgaa aggatggtgg ccttgtgtga cagaggaggg cgcgaagaag
     6061 atcctggcgg ggaagctgga aatgaccttg gagatcgttg cagaaagtga acatgaggag
     6121 cggcctgctg gccagggtcg ggatgaaccc aacatgaatc caaagctaga agatcccagg
     6181 cgccctgaca cctctttcct gtggttcacc tcaccataca agaccatgaa gttcatcttg
     6241 tggcgacgat tccggtgtgc catcatcctc ttcatcatcc tcttcatcct cctgctcttc
     6301 ctgggtgtct ttgtctacgc cttcccgaac tatgctgcca tgaagctggt gaagcccttt
     6361 agatgaagac atctgctgtg gagaaggggg cgcaggctgc ctcctggccc aggactagct
     6421 gctcctccat tgctctgggg cctggtggtc ttgcgcatgt ccacggagtt cttgggatca
     6481 caccgttttc atcttctctt tctcccctaa cccaactctc ctctggataa actcttgact
     6541 atctcagtat aaagcagaca gaacctgaga atatatcact atgtgtctcc a
//
