LOCUS       NM_001109054             883 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus dynein light chain Tctex-type 2B (Dynlt2b), mRNA.
ACCESSION   NM_001109054 XM_001072977 XM_573301
VERSION     NM_001109054.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 883)
  AUTHORS   Schmidts,M., Hou,Y., Cortes,C.R., Mans,D.A., Huber,C., Boldt,K.,
            Patel,M., van Reeuwijk,J., Plaza,J.M., van Beersum,S.E., Yap,Z.M.,
            Letteboer,S.J., Taylor,S.P., Herridge,W., Johnson,C.A.,
            Scambler,P.J., Ueffing,M., Kayserili,H., Krakow,D., King,S.M.,
            Beales,P.L., Al-Gazali,L., Wicking,C., Cormier-Daire,V.,
            Roepman,R., Mitchison,H.M. and Witman,G.B.
  CONSRTM   UK10K
  TITLE     TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy
            with impaired retrograde intraflagellar transport
  JOURNAL   Nat Commun 6, 7074 (2015)
   PUBMED   26044572
  REMARK    Erratum:[Nat Commun. 2016;7:11270. PMID: 27021811]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 883)
  AUTHORS   Gholkar,A.A., Senese,S., Lo,Y.C., Capri,J., Deardorff,W.J.,
            Dharmarajan,H., Contreras,E., Hodara,E., Whitelegge,J.P.,
            Jackson,P.K. and Torres,J.Z.
  TITLE     Tctex1d2 associates with short-rib polydactyly syndrome proteins
            and is required for ciliogenesis
  JOURNAL   Cell Cycle 14 (7), 1116-1125 (2015)
   PUBMED   25830415
REFERENCE   3  (bases 1 to 883)
  AUTHORS   Asante,D., Stevenson,N.L. and Stephens,D.J.
  TITLE     Subunit composition of the human cytoplasmic dynein-2 complex
  JOURNAL   J Cell Sci 127 (Pt 21), 4774-4787 (2014)
   PUBMED   25205765
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473967.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_573301.2, XM_001072977.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..883
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..883
                     /gene="Dynlt2b"
                     /gene_synonym="RGD1563597; Tctex1d2"
                     /note="dynein light chain Tctex-type 2B"
                     /db_xref="GeneID:498095"
                     /db_xref="RGD:1563597"
     exon            1..154
                     /gene="Dynlt2b"
                     /gene_synonym="RGD1563597; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..470
                     /gene="Dynlt2b"
                     /gene_synonym="RGD1563597; Tctex1d2"
                     /note="tctex1 domain-containing protein 2; Tctex1 domain
                     containing 2"
                     /codon_start=1
                     /product="dynein light chain Tctex-type protein 2B"
                     /protein_id="NP_001102524.1"
                     /db_xref="GeneID:498095"
                     /db_xref="RGD:1563597"
                     /translation="MAVSVRGQSLTAGASEGLSEADKTSGEPENTYILRPIFQQRFRP
                     SVVKDCIHTVLKEELTGAEYSPEEMPQLTKRLSEMIKDKLKELGYDRYKMVVQVVIGE
                     QRGEGVFMAARCFWDADTDNYTHDVFMNDSLFCVVAAFGCFYY"
     exon            155..288
                     /gene="Dynlt2b"
                     /gene_synonym="RGD1563597; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     exon            289..358
                     /gene="Dynlt2b"
                     /gene_synonym="RGD1563597; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     exon            359..422
                     /gene="Dynlt2b"
                     /gene_synonym="RGD1563597; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
     exon            423..883
                     /gene="Dynlt2b"
                     /gene_synonym="RGD1563597; Tctex1d2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcttgagacc tgctggatcc agacacagag atatggctgt gtccgtccga ggccagtcct
       61 taacggctgg cgcctccgag ggcctgtccg aggccgacaa gacctcaggg gagcctgaga
      121 acacctatat tctgaggccc attttccagc aaaggtttag accctctgtg gttaaagact
      181 gcatccatac tgtgctcaag gaagaactga caggtgctga atattctcca gaagaaatgc
      241 ctcaactcac aaaacgtcta tcagaaatga ttaaagataa gctaaaagaa ttgggatatg
      301 accggtataa aatggtggtg caggtggtga ttggagaaca gaggggtgaa ggagtattca
      361 tggctgctcg ctgtttctgg gatgcagaca cagacaacta cactcatgat gttttcatga
      421 atgacagctt attctgtgtt gtggcagcat ttggctgttt ctactactga atctttggaa
      481 agtgactgtg acttcgagga aaccttaact ttttttttct ttattctttt tttcggagct
      541 ggcgacggaa cccaggacct tgcgcttgct aggcaagcgc tctaccactg agctaaatcc
      601 ccaaccccaa accttaactt ttttatattg ttagatttcc tgaccaaata aaaaagctgg
      661 cactttggta cctaaaatct gttaagtttt atatgtttaa atggtttgat tttattttcc
      721 tatctgtgtc ctttctacat ttggaaaaag tagagaaaag ggaggggaaa attcattttc
      781 atatttcagg tgactagata cttgggtata ttttttattt attgttcctt ataagatgta
      841 aaaaaaaatc atatataaaa taaattgtgt gtcttcaccc ctt
//
